cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Yan Hendrika
Contact Email
yan.hendrika@univrab.ac.id
Phone
-
Journal Mail Official
jops@univrab.ac.id
Editorial Address
Jl. Riau Ujung No. 73 Pekanbaru Riau Telp.(0761) 38762
Location
Kota pekanbaru,
Riau
INDONESIA
JOPS (Journal Of Pharmacy and Science)
Published by Universitas Abdurrab
ISSN : 26229919     EISSN : 26151006     DOI : https://doi.org/10.36341/jops
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
JOPS is Journal Of Pharmacy and Science with Scopes of Science : 1) Pharmacy 2) Food Chemistry 3) Biotechnology 4) Pharmacology 5) Microbiology 6) Food Analysis JOPS adalah Jurnal Farmasi dan Sains dengan Ruang Lingkup keilmuan : 1) Farmasi 2) Kimia makanan 3) Bioteknologi 4) Farmakologi 5) Mikrobiologi 6) Analisa Makanan
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 130 Documents
 6   7   8   9   10 
Ultra-High Performance Liquid Chromatography (UHPLC) untuk Kuantifikasi Gabapentin dalam Granul dan Kapsul rahmayati rusnedy
JURNAL FARMASI DAN MAKANAN Vol 6 No 1 (2022): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v6i1.3013

Abstract

Ultra-High Performance Liquid Chromatography (UHPLC) has become the modern standard HPLC platform in recent years. UHPLC as an ideal separation tool for the analysis of complex mixtures with a shorter analysis time is very suitable to be used as a fast and precise method. This study aims to determine the quantitative determination of gabapentin in the form of intermediate products, namely granules and finished products, namely capsules from 1 production batch using the UHPLC method. The results of the quantitative examination of the average content (% recovery) of gabapentin in granule and capsule samples quantified by the UHPLC method met the compendial requirements and internal specifications compared to the standard gabapentin recovery values. The % recovery obtained is 98.254% for gabapentin granules and 97.784% for gabapentin capsules, which means it is still in the 95%-105% range. While the %RSD value is 0.735 for granules and 0.839 for capsules, which means it has an RSD value of <2%. % precision of gabapentin granules was 99.558% with %RSD 0.407, and % intermediate precision gabapentin capsules was obtained 98.845% with %RSD 0.678. In conclusion, based on the quantitative results obtained meet the expected specifications, so it can be considered for use for routine analysis and quality control of medicinal ingredients, in the inspection of intermediate products and other finished drug products in the pharmaceutical industry quickly and accurately.
Penetapan Kadar Total Flavonoid Ekstrak Kulit Buah Limpasu (Baccaurea lanceolata) dengan Metode Spektrofotometri Uv-Vis Risa Ahdyani
JURNAL FARMASI DAN MAKANAN Vol 6 No 1 (2022): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v6i1.3014

Abstract

Limpasu (Baccaurea lanceolata) is a native plant of Borneo which is used empirically to protect the skin from sun exposure. Limpasu contains flavonoid compounds which generally act as antioxidants. This study aims to determine the total flavonoid content of limpasu pericarp extract by using UV-Vis spectrophotometry method. Limpasu pericarp was extracted by using the stratification maceration method. This extraction was carried out by immersing the simplicia into three types of solvents with different polarities, respectively, namely n-hexane (nonpolar), ethyl acetate (semi-polar), and methanol (polar). The concentration of n-hexane, ethyl acetate, and methanol extracts was determined using a UV-Vis spectrophotometer at a maximum wavelength of 510 nm with quercetin as standard. Based on the test, it was found that the total flavonoid content of pericarp extracts, hexane, ethyl acetate, and methanol, respectively, was 44.1552 g/ml; 155.8506 g/ml; and 25.8506 g/ml. The highest total flavonoid content was found in the ethyl acetate extract.
Uji Aktivitas Antioksidan dari Formulasi Spray Gel Kombinasi Fraksi Etil Asetat Rimpang Kunyit dan Kolagen dari Ikan Patin Denia Pratiwi; Yan Hendrika
JURNAL FARMASI DAN MAKANAN Vol 6 No 1 (2022): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v6i1.3015

Abstract

Premature aging is the process of aging skin that it faster than time because there is oxidative damage caused by free radicals. This study aims to determine the antioxidant activity of the cosmeceuticals spray gel combination of turmeric rhizome fraction with catfish skin collagen. Curcumin compounds in turmeric are known to have high antioxidant activity to inhibit free radicals and the addition of collagen is intended to be able to provide intake in improving skin structure due to premature aging. The preparations are made into 8 formulas with various concentration. The preparations formed will be evaluated and tested for their antioxidant activity. The result obtained were the extraction of catfish skin collagen the yield of 12.466% collagen. Examination of the ash content, moisture content, fat and protein contain were obtained respectively 0.0105; 0.0525; 5.98; 85.76%. In the evaluation of spray gel preparations, it was found that the preparations F1-F8 met quality standards on the test of spreadability, adhesion resistance, dry time, pH, spray conditions, except for the viscosity value at F4 and F5. The highest % inhibition value was obtained at F8 (0.5% ethyl acetate fractions of turmeric rhizome and 2% collagen of catfish skin) amounted to 48.82%. In statistical t-test showed sig 0.001, indicates there are significant differences in each formula.
Luaran Klinik Terapi Antivirus pada Pasien Komorbid dan non-Komorbid T2-DM COVID-19 di RSUD Rasidin Muslim Suardi
JURNAL FARMASI DAN MAKANAN Vol 6 No 1 (2022): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v6i1.3016

Abstract

Patients with comorbidity is vulnerable to being attacked by COVID-19. Diabetes mellitus comorbid patients have experience of higher severity viral infections than those without diabetes mellitus. The objective of the research was to evaluate the impact of Type 2 Diabetes Mellitus (T2-DM) comorbidity and antiviral therapy on the clinical outcome of COVID-19 patients. The study was performed following a cross sectional design from April 2020 to March 2021 at Hospital dr Rasidin Padang. Data were collected retrospectively from the patient's medical record. Treatment and clinical outcomes of patients were analyzed using the Kruskal Wallis, Mann-Withney U Test, Repeated Measured ANOVA, and Friedman Test. Results showed that the respiratory rate on T2-DM comorbid and non-comorbid patients were 20.58±0.25 and 20.15±0.08 times/minutes, respectively (p<0.05). While, oxygen saturation was 97.95±0.16 and 98.38±0.06%, respectively (p<0.05). Patient’s length of stay after the treatment of oseltamivir and favipiravir on non-comorbid COVID-19 patients were 14.76±0.861 and 9.96±0.488 days, respectively (p<0.01). While on comorbid patients were 16.00 ±3.17 and 10.47±0.77, respectively (p<0.01). Comorbidity had a significantly impacted on the patient's respiratory rate and oxygen saturation. The use of oseltamivir and favipiravir had a highly significant different on the LOS of comorbid and non-comorbid patients.
Formulasi dan Uji Efek Lilin Aromaterapi Minyak Atsiri Daun Pandan Wangi (Pandanus amaryllifolius Roxb.) terhadap Immobility time Mencit (Mus musculus) Jantan yang Dibuat Stres Chikita Inaku; Muhammad Yusuf; Sinar Praktisi
JOPS (Journal Of Pharmacy and Science) Vol 6 No 2 (2023): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v6i2.3363

Abstract

Fragrant Pandan is a plant that has been used in traditional medicine, this leaf contains linalool compounds which are efficacious as a sedative so that it can increase a sense of comfort, and suppress aggression and anxiety. This study aimed to determine the physical stability of the aromatherapy wax formula of fragrant pandan leaf essential oil (Pandanus amaryllifolius Roxb.) and its antistress effect on male mice (Mus musculus). The design of this study was a post-test only control group design, using 25 male mice divided into 5 groups, each group consisting of 5 animals exposed to the aromatherapy wax formula of pandan leaves essential oil for 1 hour with various concentratioins of essential oils, where the group I have given 1%, group II was given 2%, group III was given 3%, group IV was given negative control, and group V was given positive control. The results of the research on the physical stability test of the aroma therapy wax formula of pandan fragrant leaf essential oil showed that the formula was organoleptically stable with white color and characteristic odor, the melting point test was stable at temperatures of FI 54O, FII 53OC, and FIII 52OC, time test FI burning shows 4 hours 28 minutes, FII 2 hours 52 minutes and FIII 3 hours 34 minutes, the preference test before and aftrer burning shows the higher the concentration of essential oils the panelists prefer. The results of the antistress effect test showed that the immobility time of mice at KI at 291 seconds, KII at 182 seconds, KIII at 88 seconds, and KIV as a negative control was higher at 334 seconds, which means that at concentrations of 1%, 2%, 3% had an antistress effect with sig analysis values Post-Hoc Tukey Statistics FIII 1,00, F IV 0,00, and FV 1,00
Analisis Senyawa Kafein pada Bubuk Kopi Jenis Arabika di Kota Takengon Menggunakan Analisis Kualitatif dan Kuatitatif Ernoviya Ernoviya; Afriadi Afriadi; Hesti Nadila Silfania
JOPS (Journal Of Pharmacy and Science) Vol 6 No 2 (2023): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v6i2.3371

Abstract

Latar belakang:Kopi merupakan jenis tumbuhan yang mengandung kafein dan dapat diolah minuman lezat. Saat ini kopi menjadi minuman paling disukai masyarakat dunia setelah air dan teh. Tujuan penelitian ini untuk mengetahui kadar kafein pada kopi bubuk arabika yang beredar di pasaran kota takengon tersebut sesuai standar nasional Indonesia (SNI 01-7152-2006). Jenis penelitian ini eksperimental dengan mengambil sampel secara purposive.Metode penelitian yang dilakukan adalah skrining fitokimia, analisa kualitatif, dan spektrofotometri ultraviolet pada panjang gelombang 273 nm. Parameter validasi yang ditentukan yaitu Presisi, lineritas, LOD dan LOQ.Hasil dari skrining fitokimia sampel A pada perlakuan uji meyer mendapatkan hasil negatif tetapi yang lainnya positif. Dan pada sampel B semua pengujian mendapatkan hasil positif. Pada ketiga pengujian analisa kualitatif pada sampel A dan B mendapatkan hasil yang positif. Hasil rata-rata analisa kuantitatif pada sampel A sekali minum 11,632 mg dan kadar sehari 34,897 mg. sedangkan pada sampel B kadar sekali minum 6,663 mg dan sehari minum 19,989 mg. Hasil uji Validasi diperoleh linearitas r2 = 0,998, LOD dan LOQ yaitu 0,882 µg/ml dan 2,94 µg/ml, nilai RSD yaitu 1,11%. Berdasarkan kesimpulan, sampel A dan sampel B memenuhi syarat menurut SNI tahun 2006 (50 mg sekali dan 150 mg sehari) dan juga memenuhi syarat menurut farmakope edisi III yaitu dosis maksimum sekali 500 mg dan sehari 1,5 g. kepada peneliti selanjutnya agar melakukan penetapan kadar selain kafein yang terdapat pada kopi arabika yang berada di kota Takengon
Pengaruh Booklet Terhadap Pengetahuan Pasien Hipertensi di Puskesmas Rasimah Ahmad Kota Bukittinggi Rizqa Hasanah; Yelly Oktavia Sari; Fatma Sri Wahyuni; Miming Andika
JOPS (Journal Of Pharmacy and Science) Vol 6 No 2 (2023): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v6i2.3384

Abstract

Hipertensi merupakan penyakit kronis yang membutuhkan terapi jangka panjang. Prevalensi hipertensi setiap tahunnya terus mengalami peningkatan, tetapi pengetahuan pasien terhadap pengobatan tergolong masih rendah. Pengetahuan yang lebih baik akan meningkatkan kepatuhan pasien dalam pengobatan sehingga tekanan darah lebih terkontrol dan terhindar dari resiko komplikasi. Penelitian ini bertujuan untuk mengetahui pengaruh booklet terhadap pengetahuan pasien hipertensi prolanis di Puskesmas Rasimah Ahmad Kota Bukittinggi. Jenis penelitian yang digunakan adalah experimental pretest–posttest control group design dengan subjek penelitian 40 responden yang dibagi secara acak menjadi dua kelompok (kontrol dan intervensi). Media intervensi yang digunakan dalam penelitian ini adalah booklet. Instrumen yang digunakan adalah kuisioner HK-LS untuk menilai pengetahuan. Hasil penelitian menunjukkan adanya peningkatan pengetahuan pasien hipertensi. Analisis statistik yang digunakan adalah uji Wilcoxon Signed Ranks, untuk mengetahui pengaruh pemberian intervensi terhadap tingkat pengetahuan pasien. Dari hasil penelitian, menunjukkan bahwa pemberian booklet memperoleh nilai signifikan (p-value = 0,000), sehingga dapat disimpulkan bahwa, pemberian booklet
Efektivitas Penggunaan Analgetik dan Antibiotik pada Pasien Pasca Operasi Fraktur Tertutup di Instalasi Rawat Inap Bedah RSUD Arifin Achmad Provinsi Riau Fridelly Mairani Apt; Fatma Sri Wahyuni; Hansen Nasif
JOPS (Journal Of Pharmacy and Science) Vol 6 No 2 (2023): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v6i2.3393

Abstract

Penelitian bertujuan untuk mengkaji gambaran sosiodemografi, nilai visual analogue scale (VAS) sebelum dan sesudah pemberian analgetik, efektivitas penggunaan analgetik dan antibiotik. Penelitian menggunakan metode analisis deskriptif dengan rancangan prospective cross sectional. Pengambilan data dilakukan secara prospektif dengan observasi langsung mengenai nyeri yang dirasa pasien menggunakan kartu VAS pada jam ke-24 pasca operasi dan setelah pemberian analgetik. Dilakukan pengamatan pada luka operasi pasien pada hari ke 3-7 sampai 30 hari pasca operasi untuk mengamati ada tidaknya ILO. Dari 40 pasien yang diteliti berdasarkan umur terbanyak adalah usia 26 tahun sampai 35 tahun (27,77%), yang paling sedikit adalah usia 45 tahun sampai 55 tahun (11,11%) dan usia 56 tahun sampai 65 tahun (11,11%). Berdasarkan jenis kelamin sebanyak 27 orang (67,50%) laki-laki dan 13 orang (32,50%) perempuan. Dari 40 pasien Sebanyak 39 pasien (97,5%) tidak terjadi ILO dan 1 pasien ( 2,5%) terjadi ILO. Sebelum pemberian analgetik seluruh pasien mengalami nyeri. Setelah pemberian parasetamol infus sebanyak 8 pasien, ketorolak injeksi sebanyak 31 pasien, dan tramadol injeksi sebanyak 1 pasien terjadi penurunan skala nyeri. Analisa data menggunakan uji wilcoxon menunjukkan adanya efektivitas penggunaan analgetik terhadap perubahan skala nyeri pada pasien (p<0,05) dan analisa secara deskriptif menunjukkan terdapat efektivitas penggunaan antibiotik pada pasien pasca operasi fraktur tertutup
Aktivitas Antibakteri dari Kulit Buah Mundar (Garcinia forbesii) Hayatun Izma; Muhammad Ikhwan Rizki; Khoerul Anwar; Dyah Anggraeni; Satrio Wibowo Rahmatullah; Aditya Maulana Perdana Putra; Dita Ayulia Dwi Sandi
JOPS (Journal Of Pharmacy and Science) Vol 6 No 2 (2023): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v6i2.3417

Abstract

Garcinia forbesii is traditionally used as medicine and cosmetics. The aimed was to determine antibacterial activity of ethanolic extract and fraction of Garcinia forbesii pericarp against Staphylococcus aureus and Propionibacterium acne based on the diameter of inhibition zone, the minimum inhibitory concentration (MIC) and the minimum killing concentration (MBC). The results showed that the largest inhibition zone diameter against Staphylococcus aureus and Propionibacterium acne was indicated by ethyl acetate fraction of 5.08±1.020 mm and 14.33±3.326 mm. The MIC value of ethanol extract against Staphylococcus aureus and Propionibacterium acne bacteria was >1.5%, n-hexane and ethyl acetate fraction had the same results, namely against Staphylococcus aureus >1.5% and Propionibacterium acne at 1.5%. The MBC value was only obtained for fraction samples of Propionibacterium acne at concentration of 1.5%. It was concluded that ethyl acetate had strong antibacterial activity against Propionibacterium acne based on the value of inhibition zone diameter, MIC, and MBC.
Gambaran Kejadian Berpotensi Medication Errors Fase Prescribing Resep Pasien Rawat Jalan RSUD Arifin Achmad Riau Wardatul Jannah; Septi Muharni
JOPS (Journal Of Pharmacy and Science) Vol 6 No 2 (2023): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v6i2.3425

Abstract

Penelitian ini bertujuan untuk melihat persentase gambaran kejadian yang berpotensi medication errors fase prescribing pada resep pasien rawat jalan di Rumah Sakit Umum Daerah Arifin Achmad provinsi Riau. Penelitian ini merupakan penelitian observasional/survei yang bersifat deskriptif. Pengambilan sampel dilakukan dengan cara accidental sampling, sampel yang didapat dalam penelitian ini sebanyak 300 lembar resep pasien rawat jalan yang masuk pada saat penelitian dilakukan di RSUD Arifin Achmad. Hasil penelitian menunjukkan bahwa persentase tertinggi kejadian yang berpotensi medication errors fase prescribing resep pasien rawat jalan RSUD Arifin Achmad berdasarkan status pembayaran adalah persentase tertinggi pada resep pasien umum yaitu sebesar 27,78%. Berdasarkan asal dokter penulis resep persentase yang didapat adalah dokter umum yaitu sebesar 26,32% . Berdasarkan jumlah obat dalam resep persentase kejadian tertinggi adalah jumlah obat ≥5 yaitu sebesar 29,44%. Berdasarkan kelengkapan resep berat badan pasien 96,67%, tinggi badan pasien96,67% dan pada penelitian ini tidak ditemukan resep dokter yang tidak dapat dibaca, serta tidak terdapat singkatan nama obat yang tidak lazim. Hasil tersebut menunjukkan, bahwa medication errors fase prescribing pada resep pasien rawat jalan di RSUD Arifin Achmad masih tinggi.

Page 8 of 13 | Total Record : 130

 6   7   8   9   10 

Filter by Year

2017 2024


Reset
Filter By Issues
All Issue Vol 7 No 2 (2024): Journal of Pharmacy and Science Vol 7 No 1 (2023): Journal of Pharmacy and Science Vol 6 No 2 (2023): Journal of Pharmacy and Science Vol 6 No 1 (2022): Journal of Pharmacy and Science Vol 5 No 2 (2022): Journal Of Pharmacy and Science Vol 5 No 1 (2021): Journal Of Pharmacy and Science Vol 4 No 2 (2021): Journal Of Pharmacy and Science Vol 4 No 1 (2020): Journal Of Pharmacy and Science Vol 3 No 2 (2020): Journal Of Pharmacy and Science Vol 3 No 1 (2019): Journal Of Pharmacy and Science Vol 2 No 2 (2019): Journal Of Pharmacy and Science Vol 2 No 1 (2018): Journal Of Pharmacy and Science Vol 1 No 2 (2018): Journal Of Pharmacy and Science Vol 1 No 1 (2017): Journal Of Pharmacy and Science More Issue