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Yan Hendrika
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JOPS (Journal Of Pharmacy and Science)
Published by Universitas Abdurrab
ISSN : 26229919     EISSN : 26151006     DOI : https://doi.org/10.36341/jops
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
JOPS is Journal Of Pharmacy and Science with Scopes of Science : 1) Pharmacy 2) Food Chemistry 3) Biotechnology 4) Pharmacology 5) Microbiology 6) Food Analysis JOPS adalah Jurnal Farmasi dan Sains dengan Ruang Lingkup keilmuan : 1) Farmasi 2) Kimia makanan 3) Bioteknologi 4) Farmakologi 5) Mikrobiologi 6) Analisa Makanan
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 220 Documents
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Profil Pengetahuan dan Persepsi Orang Tua terhadap Penggunaan Antibiotik pada Anak di Apotek Bangkalan: Knowledge Profile and Parent's Perception of Antibiotic Usage in Children at Bangkalan Pharmacy April Nuraini; M. Shofwan Haris; Dianita Rahayu Rahayu; Ratri Rokhani
JURNAL FARMASI DAN MAKANAN Vol 6 No 2 (2023): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v6i2.3426

Abstract

Antibiotics is a major therapy in infectious diseases caused by bacteria. The use of antibiotics in children often causes problems because of abuse. The purpose of this study was to determine the profile knowledge and belief about use of antibiotics based on the theory ofHealth Belief Model. The study was conducted on the parents of pediatric patients who gets antibiotic perscription in Apotek Bamara Medika Bangkalan. This research is a cross sectional research using questionnaire tools. The analysis was done descriptively. A total of 96 respondents involved in this study, as many as 24% of male respondents and 76% of female respondents. In general knowledge of the respondents are in the category quite tend to be high. Percentage is quite 36,5% and high 31,3%. Topics of knowledge with the highest score is on the topics of rules of use and understanding of antibiotics but low on the topic of resistance. Respondents 'beliefs were derived from the perceived 4 perceived values, perceived benefit, perceived barrier, perceived threat and perceived self-efficacy. The results of the respondents' perceptions show the sufficient category with the percentage of perceived benefit 41.7%, perceived barrier 39.6%, perceived threat 66.7% and perceived self-efficacy 40.7%.
Pengaruh Waktu Penggorengan dan Perebusan Daging Sapi Terhadap Kadar Protein: The Effect of Frying and Boiling Time Beef on Protein Levels Ersalina Nidianti; Dea Ayu Rahmawati
JURNAL FARMASI DAN MAKANAN Vol 6 No 2 (2023): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v6i2.3476

Abstract

Protein merupakan salah satu makromolekul yang berperan penting bagi kesehatan. Protein terdiri dari 2 jenis yaitu protein nabati dan protein hewani. Salah satu jenis protein hewani yaitu daging sapi. Sampel yang digunakan dalam penelitian ini adalah daging sapi yang mengandung zat gizi seperti protein. Penelitian ini bertujuan untuk mengetahui pengaruh waktu penggorengan dan perebusan daging sapi terhadap kadar protein dengan menggunakan metode Kjeldahl dan Spektrofotometri UV-Vis. Sampel daging sapi dilakukan penggorengan dan perebusan pada suhu 100 ℃ dengan variasi waktu 10, 15 dan 20 menit. Kemudian dilakukan metode Kjeldahl (melalui tahapan destruksi, destilasi dan titrasi) kemudian kadar protein dihitung dan dibandingkan dengan metode Spektrofotometri UV-Vis. Hasil penelitian menunjukkan kadar protein yang dilakukan metode Kjeldahl pada penggorengan kontrol (6%), sampel selama 10 menit sebesar (5%), 15 menit sebesar (4%) dan 20 menit sebesar (2%). Sedangkan hasil kadar protein yang dilakukan perebusan kontrol (7%), sampel 10 menit sebesar (6%), 15 menit sebesar (5%) dan 20 menit sebesar (2%). Sedangkan hasil kadar protein dengan metode Spektrofotometri UV-Vis pada penggorengan kontrol (8%), sampel selama 10 menit sebesar (8%), 15 menit sebesar (7%) dan 20 menit sebesar (5%). Sedangkan hasil kadar protein yang dilakukan perebusan kontrol (7%), sampel 10 menit sebesar (9%), 15 menit sebesar (8%) dan 20 menit sebesar (6%). Kesimpulan bahwa lama penggorengan dan perebusan 100 ℃ selama 10, 15 dan 20 menit tidak berpengaruh terhadap kadar protein pada daging sapi. Kata kunci : Kadar Protein Daging Sapi, Penggorengan, Perebusan, Metode Kjeldahl, Spektrofotometer UV-Vis
Gambaran Pengetahuan dan Pola Swamedikasi pada Mahasiswa Kesehatan di Dua Perguruan Tinggi di Kota Medan: Description of Knowledge and Self-Medication Pattern in Health Students at Two Higher Educations in Medan City Faiza Adinda; Wahyudi Wahyudi; Mawaddah Sri Rezeki Dalimunthe; Amalia Rahmi Nasution; Nurly Fadhila; Shelly Febrina
JURNAL FARMASI DAN MAKANAN Vol 6 No 2 (2023): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v6i2.3479

Abstract

Self-medication is a healing practice carried out independently by diagnosing symptoms, determining drugs and using drugs that are consumed without a doctor's prescription. The purpose of this study was to describe the knowledge and patterns of self-medication of health students at two tertiary institutions in the city of Medan. The research method is descriptive quantitative with a survey design. The data collection is the distribution of questionnaires viagoogle forms.Processing data using techniquesprobability samplingthat issimple random sampling.The results of the research are that self-medication knowledge in the good category is owned by PT(A) 57.7% and 63.5% PT(B), very good 38.5% PT(A) and 30.8% PT(B), not good 3.8% PT(A) and 3.8% PT(B), and not good at PT(B) at 1.9%. In terms of selfmedication patterns/efforts, 71.2% PT(A) and 51.9% PT(B) were in good category, very good 26.9% PT(A) and 44.2% PT(B). not good 1.9% PT(A) and 1.9% PT(B), and not good 2% on PT(B). The conclusion of this study shows that health students from both PTs have knowledge in the good category, but PT(A) is slightly better regarding knowledge (96.2%) and self-medication patterns (98.1%) than knowledge (96.3%) and self-medication pattern (96.1%) PT(B).
Preparasi dan Karakterisasi Sifat Fisikokimia Multikomponen Ketoprofen dengan Koformer Proline: Preparation and Characterization Physicochemical Properties of Ketoprofen with Proline Coformers Helen Sonita; Salman Umar; Erizal Zaini
JURNAL FARMASI DAN MAKANAN Vol 6 No 2 (2023): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v6i2.3485

Abstract

Ketoprofen is a non-steroidal anti-inflammatory compound (NSAID) which has low solubility in water. The aim of this study was to increase the dissolution rate of ketoprofen by forming multicomponent ketoprofen-Proline with ratio of 1:1, 1:2, and 2:1 by using solid state grinding method. Samples were characterized by Powder X-Ray Diffractometry (PXRD), Differential Scanning Calorimetry (DSC), Fourier Transform Infrared (FTIR) Spectroscopy, scanning electron microscope (SEM) analysis, solubility test, dissolution rate profile, and stability test. The results indicates the formation of a eutectic mixture of ketoprofen-Proline. From the study of the ketoprofen–proline eutectic mixture, the eutectic point in ratio 2:1 was obtained 54,763℃. The PXRD spectra did not form new crystal habit, the highest solubility test of the eutectic mixture of ketoprofen-proline showed an increase respectively 2,671 times in ratio 1:2. Stability test showed that ketoprofen-proline was not stable at 75% relative humidity (RH) 40℃ degree during 6 months storage because it deformed the solid phase into the liquid phase.
Korelasi Tingkat Kepatuhan Pengobatan terhadap Kadar Glukosa Darah pada Pasien Geriatri Diabetes Melitus Tipe 2 di Puskesmas Kota Padang: Correlation of Medication Adherence to Blood Glucose Levels among Geriatric Patients with Type 2 DM at Health Center in Padang widya kardela; Endang Agustina; Rangti A. Harartasyahrani; Rezlie Bellatasie
JURNAL FARMASI DAN MAKANAN Vol 6 No 2 (2023): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v6i2.3504

Abstract

Uncontrolled blood glucose levels in DM patients can cause various microvascular and macrovascular complications. One of the main problems causing uncontrolled blood glucose in type 2 DM patients is non-adherence to medication therapy, especially in geriatric patients. This study aims to assess the rate of medication adherence and blood glucose levels, then to analyze the relationship between the rate of medication adherence and blood glucose levels among geriatric patients with type 2 DM at the Nanggalo Health Center, Padang. Medication adherence was assessed using the ARMS-D questionnaire which had been tested for validity and reliability. Prospective data collection using a cross-sectional quantitative design with purposive sampling technique, data were analyzed by fisher's exact test. The results showed that of the 45 patients, most were classified as suboptimal adherence patients (82.2%), and the majority of patients had uncontrolled blood glucose levels (62.2%). Based on the results of the correlation test, the value of p = 0.003 (p <0.05). Hence, there is a significant relationship between the rate of medication adherence and blood glucose levels among geriatric patients with type 2 DM at the Nanggalo Health Center, Padang.
Uji Efektivitas Mukolitik Ramuan Buah Adas (Foeniculum vulgare Mill.) Secara In Vitro pada Putih Telur Bebek: Mucolytic Effectiveness Test of Fennel Fruit Concoction (Foeniculum vulgare Mill.) in Vitro on Duck Egg White Desy Aryanti Pardilla Vitri; Rismiyati Rismiyati; Julia Eka Putri Ananda; Muhammad Syach; Nindia Oktaviani Adira; Siti Rahmatul Aini
JURNAL FARMASI DAN MAKANAN Vol 6 No 2 (2023): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v6i2.3507

Abstract

Fennel (Foeniculum vulgare) empirically has been widely used by the community as a cough medicine with added honey. This study aims to determine the mucolytic activity of fennel herb in vitro on duck egg white with a concentration of 10% and 20%. A Fennel fruit concoction is obtained by brewing it with hot water and adding a teaspoon of honey. Concoctions of 10% and 20% fennel fruit were added with tween 80 and a mixture of duck egg white and phosphate buffer solution pH 7. Ambroxol HCl 3% was used as a positive control while mucus without boiling fennel was used as a negative control. The sample was tested using an Ostwald viscometer and its density was measured with a pycnometer. The data obtained is then processed to obtain the viscosity value. The results were analyzed by a one-way ANOVA statistical test and continued with the LSD test. The result showed that there was a significant difference between the negative control and the positive control, with concentrations of 10% and 20% (p < 0.05) and there was no significant difference between the positive controls with concentrations of 10% and 20% (p > 0.05). From this study, it can be concluded that the decoction of fennel fruit with added honey is proven to have mucolytic activity at concentrations of 10% and 20%.
Formulasi dan Uji Aktifitas Antikutu Kepala (Pediculus humanus capitis) Sediaan Sampo Minyak Sereh Wangi (Citronella oil): Formulation and Test of Anti-Head Lice Activity (Pediculus humanus capitis) Citronella Oil Shampoo Preparation (Citronella oil) nesa agistia; Nofriyanti Nofriyanti; Ratna Sari Dewi
JURNAL FARMASI DAN MAKANAN Vol 6 No 2 (2023): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v6i2.3578

Abstract

One of the problems that reduce a person's confidence is pediculosis. Natural ingredients used as anti-lice are citronella oil (Citronella oil), citronella oil contains citronellal compounds. This study aims to obtain a shampoo preparation that has anti-head lice activity. Citronella oil is formulated in several concentrations, namely 5% (FI), 7.5% (FII) and 10% (FIII). Evaluation of shampoo preparations included organoleptic examination, pH, homogeneity, foam height, irritation, cleaning power, freeze and thaw and anti-lice activity. Data analysis used the One Way ANOVA statistical test to see the comparison formula against the time of tick death. Based on the evaluation of the preparations, it was found that the shampoo had a thick liquid consistency, white in color, had a distinctive smell of citronella oil and no phase separation, pH 5.62-5.69, homogeneous, good cleaning power test, non-irritating, stable, anti-lice activity test FI = 6.24 minutes, FII = 5.38 minutes, FIII = 3.68 minutes, there was a significant difference (p<0.05) between the formulas on the time of tick death.
Uji Efektivitas Ekstrak Etanol Biji Mahoni (Swietenia Mahagoni (L.) Jacq) Sebagai Antihipertensi terhadap Tikus Putih Jantan Galur Wistar: Effectiveness Test of Mahogany (Swietenia Mahagoni (L.) Jacq) Seed Ethanol Extract as Antihypertensive Against Wistar Strain Male White Rats Miming Andika; Charissa Novita; Harry Ade Saputra; Rizqa Hasanah
JURNAL FARMASI DAN MAKANAN Vol 6 No 2 (2023): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v6i2.3585

Abstract

Hypertension or high blood pressure is a condition where a person's blood pressure is above the normal limit, which is indicated by a systolic pressure above 140 mmHg and a diastolic pressure above 90 mmHg. This study aimed to determine the effectiveness of ethanol extract of mahogany seeds as an antihypertensive against male galur wistar white rats strain. The research was True Experimental with Pre-Test Post-Test Control Group Design, using male white rats as test animals divided into 6 groups, namely negative control group, positive control group, dose group (100, 200 and 400 mg/kgbw) and comparison group (Captopril 25 mg). The inducer used was 8% NaCl for 30 days. Blood pressure measurements were carried out using a CODA Non-Invasive Blood Pressure (NIBP) device. Data analysis using one-way ANOVA followed by the Bonferroni test showed that administration of mahogany seed ethanol extract had an effect on decreasing systolic, diastolic, mean arterial blood pressure and heart rate significantly (p<0.05). It can be concluded that the most effective dose of mahogany seed ethanol extract in lowering blood pressure (systolic, mean arterial and heart rate) was a dose of 200 mg/kgbw and for diastolic blood pressure the most effective was the comparison drug.
Skrining Fitokimia Dan Perbandingan Kadar Vitamin C Pada Buah Apel Impor Dan Buah Apel Lokal Yang Dijual Di Pasar Buah 88 Pekanbaru Menggunakan Metode Spektrofotometer UV-Vis: Phytochemical Screening and Comparison of Vitamin C Levels in Imported and Local Apples Sold at Pekanbaru 88 Fruit Market Using the UV-Vis Spectrophotometer Method Lovera Anggraini; Nia Oktavia
JURNAL FARMASI DAN MAKANAN Vol 6 No 2 (2023): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v6i2.3586

Abstract

Apple is a fruit that contains a lot of fiber to maintain intestinal health and smooth digestion. Apples also contain lots of low-calorie protein and high vitamin C. Vitamin C is a compound that is important for health and beauty because of its antioxidant properties. Vitamin C levels in apples vary depending on the type of environment and where they grow. The aims of this study were to determine secondary metabolites and to compare the levels of vitamin C in imported apples and local apples sold at 88 Fruit Market, Pekanbaru City. Phytochemical screening in the form of reaction tests color to determine the secondary metabolites of imported apples and local apples. Imported and local apples contain secondary metabolites in the form of flavonoids,alkaloids and tannins. Comparison of vitamin C levels using the UV-Vis Spectrophotometry method. The maximum wavelength of vitamin C obtained was 264 nm with an absorbance of 0.491. The linear regression equation is y=0.0794x- 0.0048. The results of a comparison of the levels of vitamin C in imported apples and local apples, imported apples 56.13 mg/100g and local apples 69.32 mg 100g.
Efektivitas Anthipertensi Calsium Channel Blocker Dibandingkan Angiostensin Reseptor Blocker Pada Pasien Hipertensi Gangguan Ginjal. Ekanita Desiani; Siti Fatimatul Azahro
JURNAL FARMASI DAN MAKANAN Vol 7 No 1 (2023): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v7i1.3548

Abstract

Hypertension can cause damage to blood vessels in the kidneys so that the kidneys cannot filter blood properly. Appropriate and effective management of hypertension complicated by kidney disorders is needed in patients with kidney disorders to control blood pressure and slow down the occurrence of cardiovascular disease. The use of combination Calcium Channel Blocker antihypertensive drugs compared to combination Angiostensin Receptor Blockers has a therapeutic effect on lowering blood pressure in hypertensive patients with renal impairment. This study aims to determine the effectiveness of the use of antihypertensive Calcium Channel Blockers (CCB) combination compared to Angiotensin Receptor Blocker (ARB) combination in hypertensive patients with renal impairment outpatients at RSUD Kraton Pekalongan. This study is a non-experimental observational study with retrospective data on hypertensive patients with renal impairment from January to December 2022. The samples in this study were medical records of outpatients with hypertension and renal impairment who were given antihypertensive drugs of the CCB and ARB combination groups at the Public Hospital. Kraton that met the patient inclusion criteria. The results showed that the highest percentage of patients were over 60 years of age with 25 people (48%), male sex with 32 people (62%), use of antihypertensive drugs class ARB + diuretics with 16 people (30.7%) and use of antihypertensive group ARB + CCB + diuretic in 16 people (30.7%), the use of combined ARB and CCB drugs resulted in no increase in GFR in 29 people (55.7%) with the result p value = 0.570 p , the effect of drug use The combined ARB and combined CCB resulted in a decrease in blood pressure in 42 people (80.6%) with a p value = 0.178 p. Based on the results of the study, it can be concluded that the most patients are patients aged over 60 years with the sex of male patients, and there is no difference in the effectiveness of using antihypertensive groups CCB and ARB in hypertensive patients with kidney disorders in outpatient care at Kraton Pekalongan Hospital

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