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The Indonesian Journal of Infectious Diseases
Published by RSPI Prof. Dr. Sulianti Saroso
ISSN : 23546077     EISSN : 25991698     DOI : https://doi.org/10.32667/ijid.v10i1
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
The Indonesian Journal of Infectious Diseases aims to disseminate and facilitate discussions on scientific papers related to health, particularly focusing on infectious diseases including emerging diseases, new emerging disease issues, and tropical medicine. The journal serves as a communication medium for various stakeholders interested in health research, including researchers, educators, students, healthcare practitioners, the Department of Health, Public Health Service, and the general public with an interest in this field. It endeavors to address the increasing demand for studying infectious diseases.
Arjuna Subject : Imunologi dan Mikrobiologi (semua kategori) - Imunologi dan Mikrobiologi (Lain-Lain)
Articles 159 Documents
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Faktor-faktor Berhubungan dengan Kejadian Malaria di Provinsi Nusa Tenggara Timur Tahun 2018 Marisa, Amelia; Wahyono, Tri Yunis Miko; Nasution, Helmi Suryani; Sitanggang, Hendra Dhermawan
The Indonesian Journal of Infectious Diseases Vol. 10 No. 2 (2024): The Indonesian Journal of Infectious Diseases
Publisher : Rumah Sakit Penyakit Infeksi Prof Dr. Sulianti Saroso

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32667/ijid.v10i2.294

Abstract

Latar belakang: Provinsi Nusa Tenggara Timur, Indonesia termasuk daerah endemik infeksi malaria. Provinsi tersebut memiliki angka API yang tinggi secara nasional. Tujuan: untuk mengetahui faktor-faktor yang berhubungan dengan kejadian malaria di Provinsi Nusa Tenggara Timur Tahun 2018. Metode: penelitian ini merupakan penelitian kuantitatif analitik dengan desain studi Cross Sectional dengan menggunakan sebagian data Riset Kesehatan Dasar Tahun 2018. Populasi yaitu seluruh masyarakat yang tinggal di Provinsi Nusa Tenggara Timur. Jumlah sampel sebanyak 3.746 responden. Variabel antara lain kejadian malaria, jenis kelamin, umur, pendidikan, pekerjaan, jumlah anggota rumah, tempat tinggal, ventilasi rumah dipasang kasa nyamuk, pemakaian kelambu, dan pemakaian obat nyamuk. Hasil: variabel yang bermakna memiliki korelasi dengan kejadian malaria yaitu variabel jenis kelamin (nilai p=0,004; PR=1,23), umur (nilai p=0,031; PR=1,45), pekerjaan (nilai p=0,002; PR=1,32) dan ventilasi rumah dipasang kasa nyamuk (nilai p=0,008; PR=2,31). Kesimpulan: Penelitian ini menunjukkan faktor risiko yang berpengaruh terhadap kejadian malaria adalah jenis kelamin, pekerjaan dan ventilasi rumah dipasang kasa nyamuk. Faktor yang paling berpengaruh terhadap risiko kejadian malaria adalah ventilasi rumah dipasang kasa nyamuk, sehingga diharapkan adanya perilaku pencegahan malaria berupa penggunaan kasa nyamuk pada jendela atau ventilasi rumah.
Pengaruh Rebusan Daun Ubi Jalar Ungu Terhadap Peningkatan Trombosit pada Pasien Demam Berdarah Dengue Kambu, Yowel; Samaran, Elisabeth
The Indonesian Journal of Infectious Diseases Vol. 10 No. 2 (2024): The Indonesian Journal of Infectious Diseases
Publisher : Rumah Sakit Penyakit Infeksi Prof Dr. Sulianti Saroso

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32667/ijid.v10i2.296

Abstract

Latar belakang: Demam Berdarah Dengue (DBD) adalah penyakit infeksi akut endemik dengan etiologi virus dengue melalui gigitan vektor aedes aegypti betina yang dapat menyebabkan trombositopenia dan peningkatan hematokrit yang berakibat pada peningkatan permeabilitas kapiler dan pendarahan dengan risiko kematian yang tinggi. Tujuan:  untuk menentukan efek dekoksi daun ubi ungu dalam meningkatkan kadar trombosit pada pasien DBD. Metode: Pre-posttest eksperimen semu dengan pendekatan kelompok kontrol menggunakan teknik pengambilan sampel kecelakaan dengan menggunakan uji t berpasangan untuk melihat perbedaan nilai rata-rata antara kelompok yang dipasangkan dan uji t independen untuk melihat perbedaan nilai rata-rata antara kelompok kontrol dan intervensi. Hasil: DBD lebih banyak menginfeksi pria daripada wanita dan kelompok usia terbanyak adalah 11-40 tahun. Kesimpulan: Hasil statistik menunjukkan bahwa ada efek (p=0,00) dekoksi daun ubi ungu dalam meningkatkan kadar trombosit pada pasien DBD di Sorong. Saran perlu dilakukan edukasi pemberdayaan masyarakat yang inovatif dalam penggunaan sumber daya alam lokal untuk mencegah DBD.  
Ko-Infeksi TB-HIV terhadap Kegagalan Pengobatan Pasien Tuberkulosis Resistan Obat di Indonesia Laili, Fitrianur; Ronoatmodjo, Sudarto; Murtiani, Farida
The Indonesian Journal of Infectious Diseases Vol. 10 No. 2 (2024): The Indonesian Journal of Infectious Diseases
Publisher : Rumah Sakit Penyakit Infeksi Prof Dr. Sulianti Saroso

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32667/ijid.v10i2.309

Abstract

Latar belakang: Tuberkulosis merupakan infeksi oportunistik utama di antara orang dengan infeksi HIV. Berdasarkan data Kemenkes RI bahwa prevalensi ko-infeksi TB-HIV pada pasien Tuberkulosis Resisten Obat (TB RO) di Indonesia tahun 2021-2022 sebanyak 3,1%. Sedangkan angka kegagalan pengobatan TB RO berkisar 50–55% (target 20%) di Indonesia. Tujuan: Menganalisis ko-infeksi TB-HIV terhadap kegagalan pengobatan pasien TB RO di Indonesia. Metode: Desain studi penelitian ini menggunakan kohort retrospektif dengan data Sistem Informasi Tuberkulosis (SITB) tahun 2022-2023 di Indonesia dengan total sampling sebanyak 4.261 subyek. Analisis data dilakukan dengan uji chi-square, uji stratifikasi dan regresi logistik berganda dengan metode backward. Hasil: Sebanyak 68,0% pasien TB RO dengan ko-infeksi TB-HIV mengalami kegagalan pengobatan di Indonesia pada tahun 2022-2023. Pasien ko-infeksi TB-HIV memiliki risiko 2,3 kali lebih besar (95% CI: 1,6 – 3,2) untuk mengalami kegagalan pengobatan TB RO dibandingkan pasien tanpa ko-infeksi TB-HIV setelah dikontrol variabel usia. Kesimpulan: Pasien ko-infeksi TB-HIV memiliki risiko lebih tinggi terhadap terjadinya kegagalan pengobatan TB RO di Indonesia.
The Effect of Zinc Supplementation on Reducing Dengue-Related Morbidity in Pediatric Patients in Jakarta Digambiro, Reza Aditya; Setyaningrum, Dyah Ayu Woro; Dewi, Intan Keumala; Ananingsih, Pangisti Dwi
The Indonesian Journal of Infectious Diseases Vol. 11 No. 1 (2025): The Indonesian Journal of Infectious Diseases
Publisher : Rumah Sakit Penyakit Infeksi Prof Dr. Sulianti Saroso

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32667/ijid.v11i1.268

Abstract

Background: Dengue hemorrhagic fever is an endemic disease that causes significant morbidity, particularly in Jakarta. Based on previous studies, zinc has immunomodulatory properties that can function to improve the immune response to infections, including dengue. This study aims to evaluate the effectiveness of zinc supplementation in reducing morbidity and improving clinical conditions in pediatric patients with dengue hemorrhagic fever. Methods: This study utilized a prospective cohort method with a sample of 200 pediatric patients suffering from dengue hemorrhagic fever. The sample was divided into two groups: the intervention group (given zinc supplementation) and the control group (standard care without zinc supplementation). Laboratory assessments included serum zinc levels, severity of clinical symptoms, and hematological examination results. Results: The analysis showed a significant increase in serum zinc levels in the group given zinc supplementation, with the mean increasing from 100.34 ± 27.69 µg/dL to 104.28 ± 28.65 µg/dL on day 14 (p < 0.05). The number of patients whose clinical symptoms gradually became milder increased from 40% to 55% in the intervention group, whereas in the control group, there was a decrease in the number of patients with gradually milder symptoms, from 40% to 36%. Conclusion: Zinc supplementation is quite effective in reducing morbidity and improving clinical conditions in pediatric patients with dengue hemorrhagic fever.
The Relationship Between Climate Factors and Vector Density with the Incidence of Dengue Hemorrhagic Fever in East Jakarta Juwita, Disma; Maemun, Siti; Wibowo, Agus Ari; Suprono; Windiyaningsih, Cicilia
The Indonesian Journal of Infectious Diseases Vol. 11 No. 1 (2025): The Indonesian Journal of Infectious Diseases
Publisher : Rumah Sakit Penyakit Infeksi Prof Dr. Sulianti Saroso

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32667/ijid.v11i1.270

Abstract

Background: Dengue fever is a vector-borne disease. The high incidence of DHF in an area is influenced by living things (vector density) and non-living things (air temperature, climate, humidity, and rainfall). The purpose of the study was to determine the relationship between air temperature, climate, vector density, rainfall, humidity, and the incidence of DHF in East Jakarta in 2022. Methods: This research was an observational ecological study. This research was conducted in Cakung and Pasar Rebo sub-districts, East Jakarta. Secondary data sources were from the VBPP laboratory, BBTKL PP Jakarta, and BMKG Indonesia. Results: The results showed that the container index (CI) correlated with the incidence of DHF (r = 0.118, p = 0.001), as well as the number of ownership-positive containers for larvae correlated with the incidence of DHF (r = 0.113, p = 0.001). Meanwhile, the variables of temperature, humidity, and the free number of larvae did not correlate with the incidence of DHF. Conclusion: It is expected that the community actively drains regularly and closes water storage containers at home.  
Digital Medication Reminders to Improve Antiretroviral Therapy Adherence in Children Living with HIV: Literature Review Rahmawani, Atika; Islamia, Ina; Ningsih, Risna
The Indonesian Journal of Infectious Diseases Vol. 11 No. 1 (2025): The Indonesian Journal of Infectious Diseases
Publisher : Rumah Sakit Penyakit Infeksi Prof Dr. Sulianti Saroso

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32667/ijid.v11i1.275

Abstract

Background: Antiretroviral treatment is the treatment for people infected with human immunodeficiency virus (HIV) using anti-HIV combinations that are used for life. The main factors determining the success of ARV treatment are sustained and optimal adherence to therapy. Adherence to ARV treatment can be challenging for children and especially adolescents with HIV because ARVs must be taken for life. There are several ways to improve adherence to ARV medication directly, namely through comprehensive educational pressure, other ways can be done by utilizing technology that uses medication reminder applications such as the use of smartphones, android-based application development, electronic monitoring, Short Message Service (SMS), social media-based support, and mass media campaigns. This paper reviews the scientific evidence on technology-based ARV treatment adherence. Methods: This article is based on scientific journal searches conducted through online databases, namely Scopus, Proquest, PubMed, and Scholar, published in 2019-2023. Results: showed that using technology as a reminder to take medication can improve adherence of children with HIV in taking ARV drugs. Conclusion: The use of technology can improve adherence in children with HIV, can also reduce viral load rates, and increase CD4 levels
Analysis of Risk Factors for Pulmonary Tuberculosis in Cirascas District, East Jakarta, 2022 Sopiani, Pina; Maemun, Siti; Azijah, Izzatul; Pratiwi, Tiara Zakiyah; Saputra, Rahmat
The Indonesian Journal of Infectious Diseases Vol. 11 No. 1 (2025): The Indonesian Journal of Infectious Diseases
Publisher : Rumah Sakit Penyakit Infeksi Prof Dr. Sulianti Saroso

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32667/ijid.v11i1.276

Abstract

Background: Tuberculosis (TB) is a global public health problem, with Indonesia ranked second in the world in 2022. In East Jakarta, TB cases continue to increase, including in the Ciracas sub-district. This study aims to identify risk factors for pulmonary TB cases in the Ciracas sub-district in 2022. Methods: The method of this study was quantitative with a case-control design, involving 115 samples (23 cases and 92 controls) selected by purposive sampling technique. Results: The results showed that there was a relationship between contact history and TB patients (p=0.004; OR=6.27; 95% CI=1.86 – 21.11) and occupancy density (p=0.000; OR=29.52; 95%CI: 8.99 – 96.89) with Pulmonary TB infection. However, there was no significant relationship between gender, age, education, occupation, marital status, family income, and knowledge of patients with Pulmonary TB infection. Conclusion: In conclusion, contact with TB patients and housing density increases the risk of pulmonary TB infection. Therefore, it is recommended that isolation of TB patients to a place from the surrounding environment needs to be done to prevent transmission and airborne contamination
Spatial Mapping of Infectious Diseases Cases for Puskesmas Surveillance Officers in the Work Area of the Depok City Health Office Saputra, Rahmat; Devita, Yeni; Maemun, Siti; Fitri, Rahmi Pramulia; Zakiah, Zakiah
The Indonesian Journal of Infectious Diseases Vol. 11 No. 1 (2025): The Indonesian Journal of Infectious Diseases
Publisher : Rumah Sakit Penyakit Infeksi Prof Dr. Sulianti Saroso

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32667/ijid.v11i1.305

Abstract

Background: Reflecting on the previous Covid-19 pandemic obtained from the results of the situation analysis, the author concludes that the  Depok City Health Office must be able to conduct data analysis spatially, thus causing a lack of information about the spread of cases based on specific places such as villages and  coordinate points (GPS), this data is useful for measuring how much disease spreads in an area and can support policy making and intervention quickly and appropriately. In addition, unlucky spa data is also useful for seeing the density of vectors in an area. Methods: The research method was Quasi Experimental using the One Group Pre-Test and Post-Test research design, with  a sample size of 40 people. The data collection technique uses pre-test and post-test questions,  spatial mapping practice exercises and  data  analysis and interpretation exercises. The training will be held from 19 to 20 November 2021 at the Depok City Health Office hall. The data analysis test used the Paired T-Test, because the data was not normally distributed, it was continued using Wilcoxon analysis. Results: The results of the study obtained a Z value of -5.581 with an Asymp value. Sig. (2-tailed) by 0.000. Because this value is < alpha (0.05), it can be concluded that there is a significant increase in knowledge by 5.6 times after receiving training. Conclusion: To improve the performance of officers in terms of spatial mapping of infectious diseases, it is expected to conduct evaluations every 3-6 months and transfer knowledge from old officers to new officers if there is a change of officers
Detection of Tuberculosis Cases Among Correctional Facility Inmates in Indonesia Karlinda, Amelia Yuri; Syarif, Syahrizal
The Indonesian Journal of Infectious Diseases Vol. 11 No. 1 (2025): The Indonesian Journal of Infectious Diseases
Publisher : Rumah Sakit Penyakit Infeksi Prof Dr. Sulianti Saroso

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32667/ijid.v11i1.404

Abstract

Background: Tuberculosis (TB) remains a major health burden in correctional facilities, with incidence rates significantly higher than in the general population due to confined and overcrowded environments. Systematic screening is an essential approach to detecting TB cases early; however, national data on the effectiveness of systematic screening in Indonesian correctional facilities remains limited. Methods: This cross-sectional study utilized data from TB screening of 206,337 inmates across 376 correctional facilities in Indonesia conducted between July and December 2023. Screening included symptom assessment and chest X-ray (CXR) examination, followed by rapid molecular testing (TCM) for suspected cases. Analysis was performed to evaluate the proportion of TB case detection and the association between screening results and TB diagnosis. Results: A total of 4,881 TB cases were identified, with a detection proportion of 2.37% and a prevalence rate of 2,369 per 100,000 inmates. Systematic use of CXR successfully identified TB cases, including among asymptomatic inmates, with 25.99% of inmates showing abnormal CXR findings confirmed to have TB. There was a statistically significant association between CXR results and TB case detection (p < 0.001). Conclusion: Systematic screening combining symptom assessment, CXR, and TCM is effective in enhancing early TB case detection in correctional facilities. These findings reinforce the need for widespread implementation of comprehensive screening strategies, strengthening of healthcare services, and infection control measures to reduce the TB burden in Indonesian correctional settings.

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