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ISM (Intisari Sains Medis) : Jurnal Kedokteran

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Published by Universitas Udayana

ISSN : 25033638 EISSN : - DOI : -

Core Subject : Health, Science,

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

Intisari Sains Medis is published by Medical Scientific Community, Indonesia. Intisari Sains Medis is an international, multidisciplinary, peer-reviewed, open access journal accepts papers for publication in all aspects of Science Digest, Medical Research Development, Research Medical Field and Theory. We also publish cases from third world country, that is considered very rare and special cases.

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Articles 1,063 Documents

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Korelasi antara persentase lemak tubuh dan rasio lingkar pinggang-lingkar pinggul dengan kebugaran fisik pada mahasiswa Fakultas Kedokteran Universitas Mataram Ida Ayu Eka Widiastuti; Seto Priyambodo; Gede Wira Buanayuda
Intisari Sains Medis Vol. 11 No. 2 (2020): (Available online: 1 August 2020)
Publisher : DiscoverSys Inc.

Background: Body composition, is one of the factors that play a role in physical fitness. Body composition can be measured by calculating body fat percentage and waist-hip circumference ratio. Excessive body fat, usually will have a negative effect on physical fitness. The purpose of this study was to determine the correlation between body fat percentage and waist-hip circumference ratio with physical fitness.Methods: This study is a descriptive analytic study with a cross sectional design. The subjects were 82 medical students of Universitas Mataram who met the research criteria. Body fat percentage was measured by body composition monitor and physical fitness obtained from maximal oxygen uptake values (VO2max) that were calculated from the results of the Queen College Step Test. Data were analyzed by using the Pearson correlation test.Results: The results showed that the mean of body fat percentage, waist-hip circumference ratio, and VO2max were 28.3 kg/m2, 0.87 cm, and 37.7 ml/kg/minute, respectively. There was a significant correlation between body fat percentage and physical fitness (p = 0.02; r = -0.256) while there was no significant correlation between the waist-hip circumference ratio and physical fitness (p â‰¥ 0.05).Conclusion: The higher the body fat percentage, the lower the level of physical fitness.Â Latar belakang: Komposisi tubuh, merupakan salah satu faktor yang berperan dalam kebugaran fisik. Komposisi tubuh dapat diukur dengan menghitung persentase lemak tubuh dan rasio lingkar pinggang-lingkar pinggul. Seseorang yang memiliki kadar lemak tubuh yang berlebih, hampir selalu akan memberikan efek negatif terhadap kebugaran fisik. Tujuan penelitian ini adalah mengetahui korelasi antara persentase lemak tubuh dan rasio lingkar pinggang-lingkar pinggul dengan kebugaran fisik.Metode: Penelitian ini merupakan penelitian analitik deskriptif dengan desain cross sectional. Subjek penelitian adalah 82 mahasiswi Fakultas Kedokteran Universitas Mataram yang memenuhi kriteria penelitian. Dilakukan pengukuran persentase lemak tubuh dengan body composition monitor, pengukuran lingkar pinggang dan pinggul, dan nilai kebugaran fisik diperoleh dari nilai ambilan oksigen maksimal (VO2max) yang dihitung dari hasil Queen College Step Test. Data dianalisis dengan menggunakan uji korelasi Pearson.Hasil: Hasil penelitian menunjukkan bahwa rerata persentase lemak tubuh, rasio lingkar pinggang-lingkar pinggul, dan VO2max subjek masing-masing adalah 28,3 kg/m2, 0,87 cm, dan 37,7 ml/kg/menit. Terdapat korelasi bermakna antara persentase lemak tubuh dengan kebugaran fisik (p = 0,02; r = -0,256) sementara tidak terdapat korelasi bermakna antara rasio lingkar pinggang-lingkar pinggul dengan kebugaran fisik.Simpulan: Semakin tinggi persentase lemak tubuh maka semakin rendah tingkat kebugaran fisiknya.

Weightlifting-related injuries Jonathan David Rajaratnam Peter; I Putu Adiartha Griadhi
Intisari Sains Medis Vol. 11 No. 3 (2020): (Available online: 1 December 2020)
Publisher : DiscoverSys Inc.

Background: Each year, more and more athletes partake in weightlifting, aiming to outperform their predecessors and achieve new records of feats of strength. However, even despite the newer knowledge of biomechanics, and the safety precautions taken to prevent injury, such events still do take place.Aim: The study aims to determine the sources of these injuries, as well as the more frequent parts of the body that get injured, those more prone to it.Conclusion: The numerous injuries that can be sustained during weightlifting has been noted including its causes, as well as its effect on an individual and the incidence rate of the occurrence in professional weightlifters.

Ginjal tapal kuda dengan hidronefrosis unilateral sekunder akibat atresia ureter: laporan kasus Putu Kurnia Darma Pratama; Gede Wirya Kusuma Duarsa; Gusti Ayu Putu Nilawati; Pande Putu Yuli Anandasari
Intisari Sains Medis Vol. 10 No. 2 (2019): (Available online: 1 August 2019)
Publisher : DiscoverSys Inc.

Background: Total prevalence of multiple congenital anomalies (MCA) was 15.8 per 10,000 births. Genitourinary anomalies were associated with MCA cases about 43.8% of the cases. The horseshoe kidney is one example of genitourinary anomalies related to the high incidence of MCA and up to one third also had hydronephrosis thought to be secondary to ureteric atresia.Case: A 10-month-old boy presented with a 5-month history of abdominal distention. On physical examination, there was a large non-tender cystic mass in the right upper abdomen extending down to the right lower abdomen. The other congenital anomalies on this patient were hydrocephalus, hypospadias, and bilateral undescended testis. Abdominal CT showed a significant right hydronephrosis with megaureter and mesenteric cyst. The horseshoe kidney was unclear. The surgical approach to the kidney was via a transverse upper abdominal transperitoneal incision. Exploration revealed a horseshoe kidney with cystic mass situated retroperitoneally on the right side, massive dilatation of renal pelvis and proximal ureter 3 cm from UPJ. The distal ureter was markedly atresia. It was decided to perform nephroureterectomy on the right side considering its thin renal cortex. The postoperative average urine production is 25 ml/hour, no bleeding from surgical wound, BUN 10.7 mg/dL, and serum creatinine 0.37 mg/dL.Conclusion: The horseshoe kidney is one example of genitourinary anomalies related to the high incidence of MCA. Up to one third with horseshoe kidney had hydronephrosis secondary to ureteric atresia, which can be managed by reconstruction surgery or nephroureterectomy considering the function of the affected side of kidney.Â

Kesulitan diagnosis pada kasus fraktur kondilus lateral humerus pada anak di bawah umur dua tahun: laporan kasus Surya Adisthanaya; Anak Agung Ngurah Ronny Kesuma
Intisari Sains Medis Vol. 11 No. 3 (2020): (Available online: 1 December 2020)
Publisher : DiscoverSys Inc.

Background: The lateral humeral condylus fracture in a child can be difficult to diagnose because the bones of a child not ossification yet. This resulted the fracture is difficult to see or even pass in viewing. In management, the lateral humeral condylus fracture in children has controversy, between non-operative and operative (especially in fracture with minimal displace). This case report discusses the case of the humeral lateral condyle fracture in a two-year-old child and discusses its treatment.Case: A two-years-old boy was delivered by his parents to the Emergency Room (ER) in the Wangaya Regional General Hospital Denpasar with complaints of pain in the left elbow since a day ago. Complaints appear after the patient falls on the floor in his home while playing with his brother. On physical examination of the upper extremity, the left elbow is swollen at the elbow with minimal deformity without an open wound. In manage it, open reduction surgery is performed by apply Kirschner-wire and then backslab is placed on the left arm with supination and 30o flexion positions.Conclusions: Difficulties in diagnosing humeral lateral condylus fractures in children are due to the fact that there are still many condyle plates that have not ossification yet, so that it is difficult for radiological examination to see the fracture line. The operative actions that can be taken are open reduction with the installation of Kirschner-wire. Latar Belakang: Fraktur kondilus lateral humerus pada anak dapat sulit terdiagnosis akibat tulang anak yang belum terosifikasi. Hal ini mengakibatkan gambaran fraktur sulit terlihat atau bahkan terlewati. Dalam penatalaksanaanya, fraktur kondilus lateral humerus pada anak memiliki kontroversi, antara non-operatif dan operatif (terutama pada fraktur dengan pergeseran minimal). Laporan kasus ini bertujuan untuk membahas kasus fraktur kondilus lateral humerus pada anak umur dua tahun dan membahas tatalaksananya.Kasus: Seorang anak laki-laki berumur dua tahun diantar oleh orangtuanya ke Unit Gawat Darurat (UGD) Rumah Sakit Umum Daerah Wangaya Denpasar dengan keluhan nyeri pada siku kiri sejak satu hari yang lalu. Keluhan muncul setelah pasien terjatuh di lantai rumah saat sedang bermain dengan saudaranya. Pada pemeriksaan fisik ekstremitas atas, pada siku kiri didapatkan bengkak pada siku dengan deformitas minimal tanpa disertai luka terbuka. Dalam penanganannya, dilakukan tindakan operasi reduksi terbuka dengan pemasangan Kirschner-wire kemudian dipasang backslab pada lengan kiri dengan posisi supinasi dan fleksi 30o.Simpulan: Dalam mendiagnosis fraktur kondilus lateral humerus pada anak diakibatkan masih banyak lempeng kondilus yang masih belum terosifikasi, sehingga pada pemeriksaan radiologis sulit melihat garis frakturnya. Tindakan operatif yang dapat dilakukan berupa reduksi terbuka dengan pemasangan Kirschner-wire.

Hubungan kadar hemoglobin dengan kejang demam pada anak usia balita di RSUD Wangaya Komang Tria Anggareni; I Wayan Bikin Suryawan
Intisari Sains Medis Vol. 11 No. 2 (2020): (Available online: 1 August 2020)
Publisher : DiscoverSys Inc.

Latar Belakang: Sekitar 2-4% anak berumur 6 bulan hingga 5 tahun mengalami kejang demam dengan puncak insiden pada usia 18 bulan. Begitu pula halnya anemia, anak usia 6 hingga 30 bulan memiliki kadar hemoglobin terendah. Tujuan dari penelitian ini adalah untuk mengidentifikasi hubungan antara kadar hemoglobin dengan kejang demam.Metode: Penelitian ini merupakan penelitian analitik observasional dengan rancangan penelitian potong lintang (cross-sectional) dilakukan di Ruang Kaswari RSUD Wangaya pada Bulan Agustus 2019. Pasien anak usia 6 bulan hingga 5 tahun dengan demam >38oC dengan kejang atau tanpa kejang yang dirawat inap yang memenuhi kriteria inklusi dan eksklusi dimasukan ke dalam sampel dengan teknik consecutive sampling. Analisis bivariate dilakukan dengan uji Chi-square.Hasil: Dari 46 sampel yang didapat 20 pasien (43%) merupakan kejang demam, dan 26 pasien (57%) demam tanpa kejang. Pada kedua kelompok memiliki proporsi jumlah sampel laki-laki yang tidak jauh berbeda 60% dan 69% begitu pula dengan sampel perempuan. Kelompok usia terbanyak adalah kelompok usia 1-2 tahun yang mendominasi sekitar 37% dari sampel. Sebagian besar infeksi yang mendasari adalah infeksi saluran napas yaitu sekitar 35%. Hasil dari analisis uji Chi-square didapatkan hubungan yang signifikan antara kadar hemoglobin dan kejang demam (p<0,05).Simpulan: Ditemukan hubungan yang signifikan antara kadar hemoglobin yang rendah dengan kejang demam. Penelitian dengan rancangan prospektif perlu dilakukan untuk memastikan kadar hemoglobin sebagai faktor resiko kejang demam.

Analysis of serum albumin levels in pre and post hemodialysis among Chronic Renal Failure (CRF) patients at Dr. Wahidin Sudirohusodo Hospital, Makassar, Indonesia Marini Kala Tanan; Fitriani Mangarengi; Mutmainnah Mutmainnah
Intisari Sains Medis Vol. 11 No. 2 (2020): (Available online: 1 August 2020)
Publisher : DiscoverSys Inc.

Background: Chronic renal failure (CRF) is a clinical syndrome caused by a chronic decrease and gradual progression in kidney function. One of the complications of CRF can cause hypoalbuminemia. Hemodialysis can also cause hypoalbuminemia associated with inflammation and malnutrition due to loss of protein during dialysis. This study aims to analyze the albumin levels in pre and post hemodialysis CRF patients in Dr. Wahidin Sudirohusodo Hospital, Makassar.Methods: A retrospective study with cross sectional study design using secondary data obtained from the medical record was conducted among 50 patients at Dr. Wahidin Sudirohusodo Hospital, Makassar. Pre and post hemodialysis serum albumin levels of CRF patients from the Medical Record Installation were collected during September 2017 â€“ 2018 period. Variables assessed in this study were gender, age, albumin levels, and the comparison of albumin levels based on gender. Data were analyzed using SPSS version 22 for Windows.Results: There were 52.0% male and 48.0% of female patients in this study. Most of the respondents were age 40-49 years old interval (30.0%). There was no significant difference in albumin levels between pre (3.07Â±0.63 g/dL) and post (3.05Â±0.54 g/dL) HD patients (p=0.665). Also, There was no significant difference in albumin levels in pre and post HD patients between male (p=0.434) and female (p=0.778).Conclusion: There were no significant differences between serum albumin levels pre and post hemodialysis in patients with CRF as well as based on gender.

The characteristic of anxiety and depression among medical students at the Faculty of Medicine, Universitas Udayana, Bali in 2016 Tharsani Devi Srinivasagam; Bagus Komang Satriyasa
Intisari Sains Medis Vol. 11 No. 2 (2020): (Available online: 1 August 2020)
Publisher : DiscoverSys Inc.

Background: Anxiety and depression are some of the most prevalent mental health problems, especially among medical students. This study aims to evaluate the severity of anxiety and depression and also the prevalence of anxiety and depression faced by the students of the Medical Faculty, Universitas Udayana, Bali, IndonesiaMethods: A retrospective cross-sectional study was conducted among 95 medical students from the Faculty of Medicine, Universitas Udayana, Bali, Indonesia, during January-December 2016. The variables assessed in this study were gender, nationality, the severity of anxiety and depression, frequency, causes, symptoms, and medication usage in this study. Data were analyzed using SPSS version 20 for Windows.Results: The characteristic of anxiety and depression among medical students was predominant in female (55.8%), Indonesian students (57.9%), mild severity (89.5%), once in two weeks of frequency (52.6%), and exam as the primary causes (91.6%). Besides, most symptoms of anxiety and depression were headache (100.0%) following by paracetamol usage (94.7%) as medication.Conclusion: Several characteristics of anxiety and depression found among medical students were primarily related to the female Gender, Indonesian students, exam as the primary causes, headache symptoms, and paracetamol as the main medication uses to relieve the symptoms.

The effect of castration towards the microstructure of Hippocampus in Wistar rats Presanavathy P. Tharmalingam; Nyoman Mangku Karmaya; I Nyoman Gede Wardana
Intisari Sains Medis Vol. 11 No. 2 (2020): (Available online: 1 August 2020)
Publisher : DiscoverSys Inc.

Background: Male ageing is mostly referred to as the declining of the capacity of a man due to age. Even though the physical changes cause by ageing are noticeable, there are several effects of ageing in a male that are concealed by the physical appearance, such as a lower level of testosterone. This study aims to determine the effect of lower testosterone towards the neuron, neuroglia and vasculature of Hippocampus.Methods: An analytic observational study with two-group posttest-only randomized experiment with treatment was conducted among 10 Wistar rats (Rattus norvegicus). Variables assessed in this study were the number of neurons, neuroglia and vasculature of Hippocampus. Data were analyzed using SPSS version 17 for Windows.Results: The average number of neuron cells of Hippocampus was significantly lower in the treatment group compared with control (p=0.007). The significantly lower in the number of neuroglia and vasculature of Hippocampus was also found in the treatment group compared with the control group (p=0.014 and 0.004, respectively) following castration.Conclusion: Hence, we can conclude that the castration has a significant effect in lowering the level of testosterone, number of neurons, neuroglia and vasculature in the Hippocampus of Wistar rats.

Prevalensi dan hubungan faktor terkait tajam penglihatan pada masyarakat Desa Ngis, Karangasem, Bali tahun 2017 Haikal Hamas Putra Iqra; Kadek Tresna Yuwana; Agung Bagus Sista Satyarsa; Ni Made Ari Suryathi
Intisari Sains Medis Vol. 11 No. 2 (2020): (Available online: 1 August 2020)
Publisher : DiscoverSys Inc.

Background: Visual impairment is affected by multiple factors which consists of internal factor and environmental factor especially near work activity and outdoor activity. The role of its factor depends on geographical situation, economical condition and local culture.Aim: This study aims to determine the prevalence of visual acuity reduction and associated factors towards visual acuity of local civilians in Ngis village, Manggis sub-district, Karangasem district, Bali province in 2017.Method: This study was a cross-sectional descriptive study with a sample of 63 people aged 12-70 years old (27 male; 38 female) in Ngis village. The data was obtained through a 6 meter Snellen chart examination and an interview with a questionnaire guide.Results: The results showed a sharp reduction in vision of the local civilians was 37 people (58.7%) which varying from mild impairment untill NLP. A significant relationship (p<0,05) between outdoor activity toward reduction of visual acuity (PR=3.008 [95% CI: 1,039-8,714]). And another factor such as watching television, usage of smartphone and reading in the room (PR=0,659 [IK 95%: 0,221-1,962]; PR=0,579 [IK 95%:0,464-0,722]; PR=0,5 [IK 95%:0,092-2,706]) showed inconsistent relationship.Conclusion: There are some local civilians in Ngis Village that experienced undiagnosed sharp reduction in visual acuity which affected by multiple factorial.Â Latar Belakang: Banyak faktor yang mempengaruhi dari gangguan penglihatan yang berhubungan dengan tajam penglihatan salah satunya aktivitas jarak dekat dan aktivitas di luar ruangan. Hubungan dari faktor-faktor tersebut bervariasi bergantung pada kondisi geografis, ekonomi dan budaya dari masyarakat setempat.Tujuan: untuk mengetahui prevalensi penurunan tajam penglihatan dan hubungan faktor terkait terhadap tajam penglihatan pada masyarakat di desa Ngis, kecamatan Manggis, kabupaten Karangasem, provinsi Bali tahun 2017.Metode: Penelitian ini merupakan studi deskriptif cross-sectional dengan sampel masyarakat umur 12-70 tahun desa Ngis yang berjumlah 63 orang (27 laki-laki; 38 perempuan). Data didapatkan melalui pemeriksaan Snellen chart 6 meter serta wawancara dengan panduan kuisioner.Hasil: prevalensi penurunan tajam penglihatan penduduk desa Ngis adalah 37 orang (58,7%) dengan penurunan tajam penglihatan yang bervarisi dari penurunan ringan hingga NLP. Dari beberapa faktor terkait yang diteliti diperoleh hasil yang signifikan (p<0,05) pada faktor bekerja di luar ruangan (PR=3.008 [IK 95%: 1,039-8,714]). Beberapa faktor lainnya seperti kebiasaan menonton televisi (PR=0,659 [IK 95%: 0,221-1,962); penggunaan smartphone (PR=0,579 [IK 95%:0,464-0,722); membaca dalam ruangan (PR=0,5 [IK 95%:0,092-2,706) dan aktivitas di luar ruangan tidak menunjukkan korelasi yang signifikan.Kesimpulan: Terjadi penurunan tajam penglihatan pada penduduk Desa Ngis yang tidak diketahui sebelumnya, hal ini disebabkan oleh berbagai faktor dalam hal ini faktor lingkungan.

The short-term disadvantageous of tension-suture and spica cast application in exstrophy-epispadias complex reconstruction: a case report Ida Bagus Putra Pramana; Anak Agung Gde Oka; Gede Wirya Kusuma Duarsa; Kadek Budi Santosa; I Wayan Yudiana; Pande Made Wisnu Tirtayasa
Intisari Sains Medis Vol. 10 No. 3 (2019): (Available online: 1 December 2019)
Publisher : DiscoverSys Inc.

Background: Exstrophy-epispadias complex (EEC) represents a spectrum of genitourinary malformations and associated with another congenital anomaly. EEC is a rare congenital disability. EEC affects the genitourinary system, anterior abdominal wall, musculoskeletal system, spine and anus. The surgical outcome has a lot of potential complications in patient with EEC. The decision to first approach is important for the next step. Herein, we reported a case of EEC with several anomalies. Case Description: A new-born male was born with section cesarean at 38 weeks of gestation from 34-year-old mother, and this is from the second pregnancy. The weight was 3300 grams, and the height was 48 centimetres. There was an abdominal wall defect with an exposed evaginated bladder plate with urine draining from the defect. A complete dorsally opened urethral plate was seen from the bladder neck down to the glandular grove. The patient was diagnosed with Exstrophy-epispadias complex (EEC). A 2 stage repair was conducted in this patient. After 10 days post-operation, the wound became dehiscence and got sepsis postoperatively as well as lead to die in the day 20.Conclusion: Wound dehiscence following reconstruction is very critical inpatient with EEC. Tension suture and spica cast application can be disadvantageous inpatient with EEC.

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