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Jurnal Respirasi (JR)
Published by Universitas Airlangga
ISSN : 24070831     EISSN : 26218372     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
Jurnal Respirasi is a National journal in accreditation process managed by Department of Pulmonology & Respiratory Medicine Faculty of Medicine Airlangga University - Dr. Soetomo General Hospital, Surabaya. Publish every January, May, September every year with each of 5 (five) complete texts in Indonesian.
Arjuna Subject : -
Articles 321 Documents
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Holistic Management of Pediatric Patients with Asthma through the Family Medicine Approach: A Case Series Azwin Mengindra Putera; Dinda Sella Octaviana; Fanny Gunawan; Manika Putri Kunigara; Junjungan Nimasratu Rahmatsani; Lavenia Kurniawati; Ferrel Bramasta; Istianah Istianah; Jihan Nabila Pranjasdhina; Gerald Sebastian Davis; Ashfa Diniyya Assabella; Akbar Rizky Ramadhan; Veronika Intan Krismaningrum; Wigaviola Socha Purnamaasri Harmadha
Jurnal Respirasi Vol. 9 No. 3 (2023): September 2023
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v9-I.3.2023.229-236

Abstract

Introduction: Asthma is a global problem, with around 100-150 million people estimated to suffer from this disease. Based on data from the Centers for Disease Control and Prevention (CDC), around 8.4% of people in the United States suffer from asthma. Asthma requires holistic treatment, one of which is family medicine. However, there is a lack of data or research discussing this matter. Hence, this case report aims to provide an overview of family medicine in asthma, especially in children. Case: This study is a case series report involving four pediatric patients with asthma. Data collection was performed by conducting home visits and hetero-anamnesis. Many things affect asthma treatment apart from pharmacology, including family medicine. In this case series, the role of the family proved significant in the patient's healing and daily functioning. Conclusion: Family medicine is a type of holistic management critical in various diseases, especially asthma. Support from the patient's family and environment has an essential role in the success of asthma therapy in children.
The Impact of Particulate Matter on the Respiratory System Yolanda Edith Pratiwi; Feni Fitriani Taufik; Januar Habibi; Adityo Wibowo
Jurnal Respirasi Vol. 9 No. 3 (2023): September 2023
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v9-I.3.2023.237-245

Abstract

Nowadays, around 50% of the world's population lives in cities and urban areas and is exposed to increasingly higher levels of air pollutants including gaseous pollutants and particulate matter (PM). The latter is a key indicator of air pollution transported into the air by a variety of natural processes and human activities. The particles' size has been directly related to their potential impact on health problems. Particles of concern include small particles with diameters of 2.5 to 10 μm (coarse particles) and smaller than 2.5 μm (fine particles). Exposure to air pollutants over a long period of time not only decompensates pre-existing diseases but also leads to pulmonary and respiratory health problems such as asthma, chronic obstructive pulmonary disease (COPD), and lung cancer even in rural areas. A thorough analysis has to be provided to address the implications for policymakers. Hence, more stringent strategies can be implemented to control air pollution and prevent its health effects.
Pulmonary Aspergilloma Co-Existing with Pulmonary Tuberculosis: A Case Report in Type 1 Diabetes Mellitus (T1DM) Patient Kirana, Widya Tria; Faisal, Hana Khairina Putri; Kitagawa, Hiroki; Setiawan, Gigih; Yunus, Faisal
Jurnal Respirasi Vol. 9 No. 3 (2023): September 2023
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v9-I.3.2023.213-219

Abstract

Introduction: Pulmonary aspergilloma is a disease frequently found in immunocompromised patients. In Indonesia, around 18% of diabetes mellitus (DM) patients suffer from chronic pulmonary aspergilloma. However, data on type 1 DM (T1DM) are still limited. Case: We presented the case of a 22-year-old male admitted to the emergency room due to hemoptysis of approximately 200 ml within six hours before admission, nonspecific chest pain during cough, fever, night sweats, and weight loss of 3 kg over the last months. The patient had a history of T1DM and no prior history of respiratory diseases. Physical examination showed tachycardia, tachypnoea, subfebrile, normal body mass index, and rhonchi on the left thorax. Routine laboratory tests revealed increased blood sugar level (503 mg/dL) and HbA1c 16.4%. Chest X-ray and high-resolution computed tomography (HRCT) showed a cavity with an opaque lesion, crescent sign, consolidation, and reticulonodular infiltrate on the left lung. Rapid molecular tests, tuberculosis (TB), and serum galactomannan (GM) were negative. The patient was diagnosed with pulmonary aspergilloma, T1DM, and clinical TB. He was treated with fluconazole, insulin, and a fixed-dose combination of anti-TB. The patient refused the surgery procedure. Immediately, the hemoptysis stopped, blood glucose level was normal, and concomitant with weight gain. Conclusion: Due to innate and acquired immunity impairment, T1DM is a risk factor for pulmonary infections, including TB and pulmonary aspergilloma. Chest HRCT may help diagnose fungal balls. Though the patient refused to undergo surgery, administering antifungal, anti-TB drugs, and glucose control as initial treatment presented a good prognosis in the patient.
The Impact of COVID-19 on Birth Weight during Pregnancy Arien Dwi Ajeng Adhe Safitri; Isnin Anang Marhana; Budi Prasetyo; Dominicus Husada; Erni Rosita Dewi
Jurnal Respirasi Vol. 9 No. 3 (2023): September 2023
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v9-I.3.2023.176-181

Abstract

Introduction: Coronavirus is a viral pathogen that can be transmitted through respiratory droplets, leading to severe infectious diseases. This study aimed to ascertain the influence of the COVID-19 pandemic on birth weight during pregnancy. Methods: This study used secondary data and a retrospective case-control approach for observational analysis. The case and control groups each had 153 samples. The case group was further separated into symptomatic and asymptomatic categories. Statistical analyses were performed to determine how COVID-19 infection in pregnant women affected birth weight. Fisher's exact test was used to evaluate data for the subgroups of asymptomatic and symptomatic individuals, while the Mann-Whitney test was used to compare the infection's impact. Results: Most participants were 21–35 years old (78.2%). The findings showed that 85% of pregnant COVID-19 patients were in their third trimester. Mothers diagnosed with COVID-19 had infants with birth weights of >4,000 grams (3.3%), 2,500–4,000 grams (43.1%), and <2,500 grams (53.6%). Birth weight distribution in women unaffected by COVID-19 was >4,000 grams (14.4%), 2,500–4,000 grams (67.3%), and <2,500 grams (18.3%). The Mann-Whitney statistical test was performed using SPSS. It yielded a p-value of 0.001, less than the significance level of 0.05, indicating a correlation between confirmed COVID-19 infection in pregnant women and birth weight. Conclusion: This study found that the presence of COVID-19 infection during pregnancy significantly affects infants' birth weight.
Omega-6 and Omega-3 Intake Ratio in Pulmonary Tuberculosis Patients and Its Correlation with Depression Score Nabila Fawzia; Wiji Lestari; Fariz Nurwidya; Heidy Agustin; Ammar Abdurrahman Hasyim
Jurnal Respirasi Vol. 9 No. 3 (2023): September 2023
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v9-I.3.2023.194-199

Abstract

Introduction: Depression affects 45.19% of pulmonary tuberculosis (TB) patients' adherence to treatment, resulting in increased morbidity and death, medication resistance, and continued disease transmission. This study aimed to examine the relationship between omega-6/omega-3 (êž·-6/êž·-3) polyunsaturated fatty acids (PUFA) intake ratio and depression score in patients with pulmonary TB at Persahabatan National Respiratory Referral Hospital, Jakarta. Methods: This was a cross-sectional study of 99 subjects with pulmonary TB. Data were collected using the Semi-Quantitative Food Frequency Questionnaire (SQ-FFQ), anthropometric measurements, and the Beck Depression Inventory-II (BDI-II). Results: Correlation analysis used the Spearman test and revealed the ratio of êž·-6/êž·-3 PUFAs intake of 7.78 ± 1.13, the median value of depression score was 9 (10-36). There was no correlation between êž·-6/êž·-3 PUFA intake and depression score (r = 0.063; p = 0.534). Conclusion: There was no correlation between êž·-6/êž·-3 PUFAs intake ratio and depression scores in pulmonary TB patients. This is the first study to examine the correlation between êž·-6/êž·-3 PUFA intake ratio and depression score in pulmonary TB patients.
Effects of E-Cigarette Vapor Smoke on Pulmonary Alveoli in Rattus norvegicus Lungs Edward Pandu Wiriansya; Dewi Rahman; Muhammad Naufal Zuhair; Syamsu Rijal; Dzul Ikram; Utomo Andi Pangnguriseng
Jurnal Respirasi Vol. 9 No. 3 (2023): September 2023
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v9-I.3.2023.200-205

Abstract

Introduction: Vapor is considered a safer alternative to tobacco cigarettes because the high nicotine content is less. However, vapor still contains substances that are classified as toxic to humans. Short-term exposure to vapors from liquids can induce an inflammatory response in the lungs and cause oxidative stress. This study aimed to determine the effects of e-cigarette vapor smoke on pulmonary alveoli in Rattus norvegicus lungs. Methods: This was an experimental study on 32 adult male Rattus norvegicus rats. They were divided into two groups exposed to nicotine-containing vapor smoke two times a day for one and three months, respectively, and one group as control. After vapor exposure, the lung tissues of the rats were taken and then subjected to histopathological examination under a microscope. Results: After exposure for one month, epithelial and endothelial cells degenerated, characterized by a decrease in collagen and elastin fibers in the extracellular matrix. For three months, there were changes, the alveolar membrane had no nucleus, the surrounding endothelial cells were not visible due to damage to the extracellular matrix, the alveolar lumen had widened, causing edema in the lumen of the alveoli, and the alveoli wall was destroyed. Therefore, the connection between the alveoli was stretched. Conclusion: This study found that short-term exposure to nicotine vapor causes damage to the alveoli membrane.
The Degree of COVID-19 and Preeclampsia at Dr. Soebandi Hospital, Jember Sisca Puji Rahayu; Angga Mardro Raharjo; Dita Diana Parti; Yuli Hermansyah; Pipiet Wulandari; Nurul Istinaroh
Jurnal Respirasi Vol. 9 No. 3 (2023): September 2023
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v9-I.3.2023.182-187

Abstract

Introduction: The risk of preeclampsia increases due to COVID-19. COVID-19 was the leading cause of Indonesia's high maternal mortality rate in 2021, with 2,982 cases. COVID-19 cases affected the maternal mortality rate in East Java, reaching 234.7 per 100,000 live births. Jember ranks first with the highest number of deaths of pregnant women in East Java. This study aimed to examine the relationship between the severity of COVID-19 and the degree of preeclampsia at Dr. Soebandi Hospital, Jember. Methods: This was an analytic observational study with a cross-sectional design. This study was conducted from March to April 2023. A total of 27 samples of pregnant women with COVID-19 were taken using the total sampling method in 2020-2022 at Dr. Soebandi Hospital, Jember, and analyzed using SPSS with the Spearman statistical test. Results: This study found that pregnant women with mild cases of COVID-19 were 9 cases, 16 cases were moderate, and 2 cases were severe. There were 15 cases of pregnant women with no preeclampsia and 12 cases with severe preeclampsia. Conclusion: There was no relationship between the severity of COVID-19 and the degree of preeclampsia at Dr. Soebandi Hospital, Jember.
Anosmia, Dysgeusia, and Comorbidity in COVID-19 Patients with Respiratory Tract Manifestations Jason Lefranda Jocelino Siswanto; Viskasari Pintoko Kalanjati; Soetjipto Soetjipto; Azlin Muhammad Mohd Yasin
Jurnal Respirasi Vol. 9 No. 3 (2023): September 2023
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v9-I.3.2023.188-193

Abstract

Introduction: Olfactory and special sensory disturbances such as anosmia and dysgeusia have been found among COVID-19 patients. These manifestations may cause post-covid sequelae, disturbing patients' quality of life who have recovered from COVID-19. This study aimed to analyze the association between anosmia and dysgeusia with the comorbidities in adult COVID-19 patients admitted to Dr. Soetomo General Hospital, Surabaya, from 1 January 2020 to 30 September 2021. Methods: This was a cross-sectional retrospective analysis study based on the medical records of all patients who met the criteria (n = 158). The minimal age inclusion was 18 years old, and the patient must be positively diagnosed with COVID-19 (reverse transcription polymerase chain reaction/RT-PCR). Results: Out of 158 patients, all had a fever, and approximately 93% of patients showed respiratory signs and symptoms. There were 128 patients (81%) who suffered from anosmia, and 15 patients (9.5%) had dysgeusia. Significant associations were found between anosmia with dysgeusia (p = 0.049) and between anosmia with cough (p = 0.003) and dyspnea (p = 0.000). The predominant comorbidities reported were overweight (60%), hypertension (42%), and type-2 diabetes mellitus (37%). Conclusion: There were significant associations between anosmia with dysgeusia and the respiratory tract signs and symptoms instead of the comorbidities reported.
Lung Cancer: A Literature Review Yan Efrata Sembiring; Wiwin Is Effendi; Jeffrey Jeswant Dillon; Heroe Soebroto; Dhihintia Jiwangga Suta Winarno; Puruhito Puruhito; I Gusti Agung Made Adnyanya Putra; Abed Nego Okthara Sebayang; Sri Pramesthi Wisnu Bowo Negoro
Jurnal Respirasi Vol. 9 No. 3 (2023): September 2023
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v9-I.3.2023.246-251

Abstract

Lung cancer is a cancer whose onset starts in the lungs where there is an abnormal cell growth that is very fast and uncontrolled. The abnormal cell growth is triggered by deoxyribonucleic acid (DNA) damage, including deletions in the DNA section, inactivation of tumor suppressor genes, activation of proto-oncogenes to oncogenes, the absence of apoptosis, and the activity of the telomerase enzyme. Lung cancer is initiated by oncogeneous activity and inactivation of tumor suppressor genes. Oncogenes are genes that help cells grow and divide and are believed to cause a person to develop lung cancer. In general, lung cancer is divided into two types, namely non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). World Health Organization (WHO) classifies lung cancer based on histopathology into 4 major cell types, namely SCLC, NSCLC which includes adenocarcinoma, squamous cell carcinoma (SCC), and large cell carcinoma (LCC). The difference between the two is that SCLC has a higher aggressiveness than NSCLC. Cancer treatment is based on the type, size, location and stage of the cancer, as well as the patient's overall condition.
Front Matter Vol 9 No 3, 2023 Front Matter
Jurnal Respirasi Vol. 9 No. 3 (2023): September 2023
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

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