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Sumatera Medical Journal

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Published by Universitas Sumatera Utara

ISSN : 26229234 EISSN : 26221357 DOI : 10.32734

Core Subject : Health, Science,

Immunology & microbiology Medicine & Pharmacology

Sumatera Medical Journal (SUMEJ) provides a forum for publishing the full research articles in the area of Medical Science related to topics from the following subject areas: -Cancer and Related Aspects -Biomoleculer in Basic Sciences -Biomoleculer in Clinical Sciences -Tissue Engineering including Stem Cell -Medical and Health Sciences

Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)

Articles 169 Documents

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Corelation Between Sum of Precordial ST Depression in Acute Inferior Myocardial Infarction with Stenosis Severity of Left Anterior Descending Artery Karo, Kartika br; Ketaren, Andre Pasha; Hasan, Refli; Hasan, Harris; Mukhtar, Zulfikri; Lubis, Anggia Chairuddin
Sumatera Medical Journal Vol. 2 No. 1 (2019): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Background : There were many studies proved that precordial ST depression in Inferior STEMI show LAD disease from angiografi, but there were also many who unproved . Altought LAD disease was not the main cause of precordial ST depression in Inferior STEMI, but there were many patients with Inferior STEMI who had high grade LAD disease. Sum of precordial ST depression is one of ECG criteria that can help us to prove it . The aim of this study in to know if there is corelation between sum of precordial ST depression with LAD disease and the severity of LAD disease in Inferior STEMI patients with precordial ST depression . Methods : We analized 60 patients inferior STEMI with precordial ST depression onset less than 24 hours that hospitalized in Haji Adam Malik General Hospital since December 2013-June 2017. Patients were divided in to 4 groups based on sum of precordial ST depression. Bivariate analysis were made to see the corelation between sum of precordial ST depression with LAD disease and severity of LAD, p value < 0.05 is statistically significant. Result : Bivariate analysis show that there is strong corelation between sum of precordial ST depression with LAD disease (p=0.01). Sum of precordial ST depression also corelate with severity of LAD (p=0.01). There are also corelation with location of the lesion in proximal LAD and the complexity of the lesion but not statistically significant (p=0.233 and p=0.102). Analysis ROC curve sum of precordial ST depression to LAD disease give the cut off ≥5.15 mm with sensitivity 70% and spesificity 76.2%(AUC 0,752 ,95% CI: 0,620 – 0,883 p<0,001) Conclusion : There is strong corelation between sum of precordial ST depression with high grade LAD disease. The more the sum of precordial ST depression the more posibility high degree LAD disease ( p=0.01).

Blastocytosis hominis: Unboxing Its Clinical Significance Rozi, Muhammad Fakhrur; Darlan, Dewi Masyithah
Sumatera Medical Journal Vol. 2 No. 2 (2019): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Abstract. Blastocystis hominisis a unicellular parasite classified as stramenopiles found in human and other mammals. The prevalence varies depending on the region, higher in developing country. The organism is transmitted via fecal-oral route by ingestion of oocyst contaminated food or water. Travelers also have high-risk of having blastocytstis infection. Based on recent studies, several proposed virulence factor are also identified but it remains elusive. The advanced technique has been used to describe its genetic variation and diversity that might be related to its clinical significance. There are 6 distinct morphological forms of Blastocystis including vacuolar, granular, ameboid, and cystic form. The cystic form is considered as an infective form of the organism. Exposure to animals is suggested as the other transmission route, consequently, the infection is also considered as zoonotic infection. It can produce broad clinical manifestation ranging from asymptomatic, self-limiting diarrhea until severe watery diarrhea, depends on host factors and the organism subtype. The organism can produce pruritus and urticaria, proved in literature. Since its pathogenicity remains unclear, conservative management is still suggested to all asymptomatic-symptomatic blastocytosis patients in accordance to patient’s immune status.

The Relationship between Obstructive Sleep Apnea (OSA) and Adherence of Antihypertensive Consumption in Regular Hemodialysis Patient Lubis, Afrilia Rosada; Muzasti, Riri Andri
Sumatera Medical Journal Vol. 2 No. 2 (2019): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Background. Based on the Indonesian Renal Registry (IRR) data in 2015, the highest incidence of comorbidities in hemodialysis patients in Indonesia was hypertension (50%). Obstructive Sleep Apnea (OSA) is one of the causes of secondary hypertension, the characteristics of hypertension in OSA are more resistant to treatment. One of the causes of resistant hypertension is patient non-compliance with the consumption of antihypertensive drugs. Aim. To determine the relationship of adherence of consumption of antihypertensive drugs with obstructive sleep apnea in regular HD patients. Method. This cross-sectional study involved 89 outpatients in HD units at the Rasyida Kidney Hospital in 2018. Data was obtained through interview using the STOP-BANG questionnaire to assess the of risk of OSA and using Morisky Medication Adherence Scale (MMAS) questionnaire to measure the compliance of drug consumption. Results.The prevalence of OSA in HD patients was (39.3%). There was no significant relationship between adherence with drug consumption and OSA risk, but in bivariate analysis, age (p = 0.0001), body mass index (BMI) (p = 0.001), and gender (p = 0.03) were significantly related to OSA. In multivariate, age and BMI were significantly associated with OSA (OR: 6.449, 95% CI 2.246 ± 18.520, p = 0.001; OR: 6.130, 95% CI 2.105 ± 17.849, p = 0.001). Conclusion. OSA was not statistically related to adherence to antihypertensive drug consumption in HD patients but was significantly associated with age and BMI. Keyword. Adherence to antihypertensive consumption, hemodialysis, obstructive sleep apnea.

Exclusive Breastfeeding For Infant Growth and Development in Medan L. Raja, Sarma Nursani
Sumatera Medical Journal Vol. 2 No. 3 (2019): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Breast milk is one of the most perfect nutrition to ensure the growth and development of infants in the first 6 months. Exclusive breastfeeding alleged effect on infant growth and development. The purpose of this study was to analyze the influence of exclusive breastfeeding on infant growth and development. This study is a case control study in Sering Primary Health Care Medan in 2014. Anthropometric parameter of subjecs’ children were measured and plotted in the WHO graph. Then, subjects were told to undergo a 5 minute interview to analyze the pattern of breastfeeding history. In this study, both infant growth, development, and growth and development were associated with history exclusive breastfeeding (p<0.001). Exclusively breastfed infants have good growth and optimal, in contrast to infants who are not breastfed exclusively have poor growth. It was concluded that there was an influence of breastfeeding with infant growth and development.

VEGF and Cervical Cancer Stage IB – IIA Response after Chemotherapy with Ifosfamide – Cisplatin Edianto, Deri
Sumatera Medical Journal Vol. 2 No. 3 (2019): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

The aim of this study is to evaluate response of cervical cancer stage IB – IIA after neoadjuvant chemotherapy based on VEGF expression. The data were collected from 51 patients’ cervical cancer stage IB – IIA parafin blocks who received chemotherapy ifosfamide – cisplatin before radical hysterectomy at General Hospital Adam Malik Medan. VEGF expression was evaluated from cervical biopsy tissue, and response therapy was evaluated based on tumor size clinically. 20 out of 51 samples with clinically complete response, and the rest are partial response. 18 out of 20 samples with clinically complete response have negative or weak VEGF expression, and 31 out of 51 samples patients were partialy response with moderate or strong VEGF expression. 23 cases with tumor size > 4 cm and 23 cases stage IIA expressed VEGF moderately or strong. Cervical cancer with tumor size < 4 cm and cervical cenncer stage IB with less expressed of VEGF have good response with chemotherapy adjuvant ifosfamide – cis platin.Keyword: ifosfamide-cisplatin, cervical cancer, VEGF

The Relation of Allergic Rhinitis Classification with IL-5 on The Aller-gic Rhinitis Ismayani
Sumatera Medical Journal Vol. 2 No. 3 (2019): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

IL-5 is an important role cytokine on the RA. IL-5 has an important role on eosinophils. ARIA-WHO made classification of RA based on how long the clinical symptoms and the impact on quality of life. The aim of this study was to know the classification of RA with IL-5 on RA study. This study used a cross-sectional method with 39 samples. The examination of IL-5 used ELISA. The highest classification of RA was medium-severe persistent of 43.58% with the mean value IL-5 was 56.25 pg/ml. Based on the test of Kruskal Wallis, it was obtained p-value = 0.664. Conclusion: There was no significant relation between classification RA and IL-5.

Management of Congenital Aural Atresia : A Case Report Yuli Tetriana Sari; Delfitri Munir
Sumatera Medical Journal Vol. 2 No. 3 (2019): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Congenital Aural Atresia (CAA) is the failure of development of the external auditory canal. It usually occurs in conjunction with microtia, which is malformation of the auricle due to the failure of development of the external ear. The evaluation and treatment of aural atresia present a number of challenges to the otologic surgeon. Computed tomography also plays a pivotal role in planning the surgery and grading the outcome of the surgery in congenital aural atresia. We report a case of unilateral congenital aural atresia and microtia and did a canalplasty and tympanoplasty in this patient.

ANALYSIS OF LIFESTYLE, KNOWLEDGE, ATTITUDE, AND KNOWLEDGE OF WOMEN AGED 20-50 YEARS OLD WITH VITAMIN D DEFICIENCY-INSUFFICIENCY IN NORTH SUMATERA, INDONESIA Keumala, Dina; Zulkarnaini Tala, Zaimah; Lestari, Sri; Hutagalung, Sunna Vyatra; Ganie, Ratna Akbari; Harum, Delina Sekar
Sumatera Medical Journal Vol. 1 No. 01 (2017): The Sumatera Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v1i01.75

Background: Study showed that 95% women had serum level of 25(OH)D lower than normal and women have riskier lifestyle than men, this is based on women’s lifestyle, such as avoiding sun rays, sunblock application, low vitamin D intake, and low physical activity. As result of the deficiency, there will be increasing number of metabolic disorders such as obesity and diabetes mellitus type 2.Objectives: To discover lifestyle, knowledge, attitude, and action of women aged 20-50 years old with vitamin D deficiency-insufficiency regarding risk of metabolic disorder caused by vitamin D deficiency.Method: Cross-sectional study engaging 98 women participants with vitamin D deficiency-insufficiency. Lifestyle including avoiding sunlight, low physical activity, and sunblock application were assessed. The scoring was to assess knowledge, attitude and action of women aged 20-50 years old with vitamin D deficiency-insufficiency regarding risk of metabolic disorder in Medan and then the result was analyzed.Result: The study engaged 98 women aged 20-50 years old with vitamin D deficiency-insufficiency, showed vitamin D level with mean 19.66±5.69 ng/ml. There were 95% participants categorized into vitamin D deficiency-insufficiency and 5% participants categorized into vitamin D suficiency. All subjects were found to be low on sun rays exposure, high incidence sunblock applicaton, low vitamin D intake, and low physical activities. According to knowledge about risk of metabolic disorder, there were 42.3% participants with sufficient knowledge and 57.7% with deficient knowledge, and regarding attitude, 48.52% had negative attitude and 51.5% had positive attitude, regarding action, 24.7% was sufficient and 75.3% was deficient. According to the analysis, there was no significant association between action and knowledge, attitude and knowledge, but there was significant association between action and knowledge based on education (p=0.01).Conclusion: Lifestyle, sufficient knowledge, and action could be the caused of low vitamin D level. There was significant association between action and knowledge based on education, but didn’t show any associations. Based on this result, knowledge needs to be improved in order to improve attitude and action with counseling or books that are easy to be understood about the importance of vitamin D

IDENTIFICATION OF CANDIDA SPECIES ON THE SKIN OF DIABETES MELLITUS PATIENTS Al Hafiz, OK Muhammad; Amelia, Rina; Jusuf, Nelva Karmila
Sumatera Medical Journal Vol. 1 No. 01 (2017): The Sumatera Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v1i01.76

Background: Intertriginous candidiasis is a type of candidiasis which the lesion lies in the folds of the armpit, groin, intergluteal, folding of the breast, between the fingers or the toes, glans penis, and the umbilicus. One of the risk factors for intertriginous candidiasis is diabetes mellitus (DM). DM is a typical clinical syndrome characterized by the presence of hyperglycemia which is caused by deficiency or the decrease of insulin effectivity. Fungal infection of the skin with Candida species becomes easier in patients with immunocompromised conditions such as DM patients.Objective: To identify the Candida species in DM patient's skin.Method: This research is an observational descriptive study with cross sectional design. This research identifies Candida species from 30 DM patients at The Public Health Center Sentosa BaruMedan who met the inclusion and exclusion criteria by skin scraping with KOH 10% and slide culture.RESULTS: The location of the rash was found in the crotch folds 63.3% and in the intergluteal 36.7%. All samples (100%) showed positive fungus structure with KOH 10% examination. On theexamination of slide culture with Saboraoud Dextrose Agar media and identification of slide colony with Corn Meal Agar medium as many as 60% Candida spesies was found with overallspecies are Candida albicans.Conclusions: The identification of Candida Species on the skin of DM patients showed as many as 60% Candida albicans was found

PROFILE OF BRAIN TUMOR PATIENTS IN 10 HOSPITALS IN NORTH SUMATERA Rambe, Aldy S.; Fitri, Aida; Tonam, Tonam
Sumatera Medical Journal Vol. 1 No. 01 (2017): The Sumatera Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v1i01.78

Background: Although brain tumors only 1.4% of all tumors, high fatality rate made these tumors need special attention. In North Sumatera, there is no data on brain tumors patients profile.Objective: To determine brain tumor patients’ profile in North Sumatera, Indonesia.Method: A descriptive hospital-based study with primary data which taken from September–December 2012. Result: Of 75 brain tumors patients surveyed in 10 hospitals in North Sumatera 38 (50.7%) patients were male and 37 (49.3%) patients were female. Mean of age was 51.45 (11–87) years old. Most of the subjects were housewifes, 26 (34.7%) patients. The most common cause that brought these patients to see doctors was headache 32 (42.7%), followed by decreased level of consciousness 17 (22.7%). Clinical manifestations found in these patients were headache 67 (89.3%), dizziness/vertigo 41 (54.7%), convulsion 22 (29.3%), vomitting 32 (42.7%), motor dysfunction 46 (61.3%), sensory dysfunction 21 (28%), and cognitive decline 21 (28%). Only 7 patients (9.3%) had history of tumor in his/her relatives. Eighteen patients (24%) were treated surgically and 8 (10.7%) were given radiotherapy. Seventy one patients were alive (94.7%) when discharged from the hospitals due to various reasons. Head CT Scan/MRI showed primary tumors in 56 (74.7%) patients. Of these primary tumors 25 (44.6%) patients were meningioma and 19 (33.9%) were astrocytoma. Of 19 (25.3%) patients with secondary tumor, most common primary tumor were found in the lung 11 (57.9%).Conclusion: Sex the patients were equally distributed with mean of age was 51.45 (11–87) years old. The most common cause that brought these patients to seek for treatment were headache. Most of these patients were treated conservatively. The most common head CT Scan/MRI findings showed primary tumors.

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Dina Keumala Sari

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Jl. Dr. T. Mansur No. 9 Padang Bulan, Kecamatan Medan Baru, Kota medan, Sumatera Utara, Indonesia

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Sumatera utara

INDONESIA

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Dina Keumala Sari

Contact Email dina@usu.ac.id

Phone +6281397177693

Journal Mail Official sumej@usu.ac.id

Editorial Address Jl. Dr. T. Mansur No. 9 Padang Bulan, Kecamatan Medan Baru, Kota medan, Sumatera Utara, Indonesia

Location Kota medan, Sumatera utara INDONESIA

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Abstract

Contact Name
Dina Keumala Sari

Contact Email
dina@usu.ac.id

Phone
+6281397177693

Journal Mail Official
sumej@usu.ac.id

Editorial Address
Jl. Dr. T. Mansur No. 9 Padang Bulan, Kecamatan Medan Baru, Kota medan, Sumatera Utara, Indonesia

Location
Kota medan,

Sumatera utara

INDONESIA