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Veterinary Biomedical and Clinical Journal
Published by Universitas Brawijaya
ISSN : -     EISSN : 26221012     DOI : -
Core Subject : Health, Science, Education,
Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Veterinary
Veterinary Clinical and Biomedical Journal (VBCJ) is periodically peer reviewed journal that publish every January and July per year since 2019. VBCJ accommodate any articles in the field of veterinary medicine, biomedical, as well as veterinary case report.
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Articles 78 Documents
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Front Matter: Front Cover, Editorial Board, Peer Reviewers, Acknowledgments VBCJ
Veterinary Biomedical and Clinical Journal Vol. 7 No. 2 (2025): Vol. 7 No. 2 2025
Publisher : Faculty of Veterinary Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.VetBioClinJ.2025.007.02

Abstract

Front Matter
Lycopene Supplementation Mitigates Heat Stress-Induced Impairment of Embryonic Development, Survival, and Heart Rate in Zebrafish (Danio rerio) Residiwati, Gretania; Nararya, Winandana Parama; Ainurrahma, Hafidha; Lonameo, Bonick Kartini; Lesmana, Muhammad Arfan; Agustina, Galuh Chandra; Budiono; Hartono, Djoko; Hendrawan, Viski Fitri; Tuska, Habib Syaiful Arif; Sidi, Shehu
Veterinary Biomedical and Clinical Journal Vol. 8 No. 1 (2026): Vol. 8 No. 1 2026
Publisher : Faculty of Veterinary Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.VetBioClinJ.2026.008.01.1

Abstract

Fish at any change in aquaculture air temperature can affect fish survival, physiological conditions and immune response. The need to study the reaction of fish to sublethal temperatures (30-40oC) is an impetus because of global warming which can trigger heat stress (HS). Heat stress (HS) and its effects can occur in fish with any changes in the environment (physical or physiological), where heat can change the animal's normal homeostasis. Tomato (Lycopersicum esculentum), has been proven as a fruit that is rich in lycopene, which acts as a natural antioxidant. The purpose of this study was to determine the effect of lycopene supplementation on the process of external fertilization on embryo development, survival rate and heart rate of zebrafish (Danio rerio) at normal temperature (NHS) and with heat exposure (HS). The survival rate data obtained will then be analyzed using SPSS, with ANOVA and LSD tests (P ≤0.05). While the results of the statistical analysis test of heart rate, a non-parametric test was used using Kruskal-Wallis H, to find out whether there was a significant difference in the treatment; and the Mann-Whitney Test, to detect significant differences between groups (P ≤0.05). The effect of lycopene supplementation on the external fertilization process of zebrafish embryos gives a low survival rate and heart vibration of zebrafish embryos, which is thought to be caused by several factors, namely zebrafish genetics; storage method, dosage, and lycopene extraction method used in the research
Front Matter: Front Cover, Editorial Board, Peer Reviewers, Acknowledgments VBCJ
Veterinary Biomedical and Clinical Journal Vol. 8 No. 1 (2026): Vol. 8 No. 1 2026
Publisher : Faculty of Veterinary Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Front Matter
Comparative Benchmark Whole Blood Cholinesterase Inhibition by Dichlorvos in Humans and Ruminants : Whole Blood Cholinesterase Inhibition by Dichlorvos Ramadhan, Maha Ahmed; Mohammad, Fouad Kasim
Veterinary Biomedical and Clinical Journal Vol. 8 No. 1 (2026): Vol. 8 No. 1 2026
Publisher : Faculty of Veterinary Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.VetBioClinJ.2026.008.01.2

Abstract

In vitro inhibition of whole blood cholinesterase (WBChE) by the organophosphate insecticide dichlorvos has been used to assess sentinel animal species among ruminants. The aim of the study was to calculate the benchmark dose (BMD) as a sensitive indicator of WBChE inhibition caused by dichlorvos. The BMD sensitivity of WBChE of humans and ruminants (sheep, goats and cattle) was assessed after in vitro dichlorvos 10-min inhibition in the assay mixture. At concentrations of 0 (control), 0.25, 0.5, and 1 µM, dichlorvos significantly, but variably reduced enzyme activity across the four species with IC50 values of about 0.5 µM. These data were used to calculate BMD using the online tool BMDS Online Version: 25.1 software introduced by U.S. Environmental Protection Agency (US EPA). The exponential 3 curve fitting model was recommended by the tool. The resultant plots showed dose-response curves estimated by the model. The BMD levels in humans, sheep, goats and cattle were 0.181, 0.126, 0.343, 0.304 µM, respectively. The goodness-of-fit p-values ranged from 0.757 to 0.983 across the species, which were larger than the predetermined critical p-value of 0.1 used by the US EPA. The data showed that the BMD model appropriately described the observed dose-response pattern of WBChE inhibition by dichlorvos, and showed that this model was a better sensitivity indicator of enzyme inhibition s compared to IC50 determined earlier. Sheep-derived benchmark dose assessment defines this species as the most sensitive (sentinel) one among humans, goats and cattle, with regards to WBChE inhibition threshold. Refining the in vitro dichlorvos toxicity outcome with in vivo studies and risk assessment methods is needed, as this study highlights and further supports the potential of BMD modelling in evaluating health risks posed by OP insecticides.
The Effect of Sulfur and Aloe Vera Gel on Crust Length and Collagen Density in Scabies Nur Indasari, Elly; Armadhaniand, Shafa Rayya; Prasetyo, Dodik
Veterinary Biomedical and Clinical Journal Vol. 8 No. 1 (2026): Vol. 8 No. 1 2026
Publisher : Faculty of Veterinary Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.VetBioClinJ.2026.008.01.3

Abstract

Scabies infestation by Sarcoptes scabiei cause crust formation, skin damage, and impaired wound healing. This study evaluated the effectiveness of combined sulfur and aloe vera therapy on crust length and collagen density in scabies-infected white rats. A laboratory experimental study with a completely randomized design was conducted. Twenty-five male Wistar rats were divided into five groups: negative control (healthy, no infection), positive control (infected, no therapy), and three treatment groups (P1, P2, P3) infected and treated with a gel containing sulfur (5%, 10%, and 15%, respectively) in aloe vera gel for 7 days. Crust length was measured using digital calipers, and collagen density was assessed semi-quantitatively (score 0–4) on Hematoxylin-Eosin-stained ear skin sections. Data were analyzed using One-way ANOVA followed by Tukey’s HSD (crust length) and Kruskal-Wallis followed by Mann-Whitney U test (collagen density). Combined therapy significantly reduced crust length (p=0.006) and increased collagen density (p<0.05). The 5% sulfur group (P1) showed the most significant crust reduction (p=0.005) and collagen density improvement (p=0.003) compared to the positive control. In conclusion, the combination gel of aloe vera and 5% sulfur effectively reduces crust length and improves collagen density, accelerating wound healing in scabies-infected rats.
A Case Report: Diagnose and Terapeutic Management of Clinical Mastitis on Ewe Amien, Shahnaz Naufala Qonnitah; Fatmawati, Mira
Veterinary Biomedical and Clinical Journal Vol. 8 No. 1 (2026): Vol. 8 No. 1 2026
Publisher : Faculty of Veterinary Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.VetBioClinJ.2026.008.01.6

Abstract

Clinical mastitis is an inflamation of the udder that is an economical disease because it can cause a decrease in milk production. This case study aimed to determine the diagnosis and treatment of clinical mastitis in local ewes at Praktek Mandiri drh. Budi Pramono, Sleman, Yogyakarta. An ewe was reported with a swelling in the right udder. The ewe was 1,5 years old and had its first lactation with a 5-month-old lamb. Physical examination showed that the ewe had a fever, the right udder was enlarged, and no milk was produced. The diagnosis was confirmed using CMT, hematology, and ultrasonography. The CMT result from the left udder milk was positive, hematology results showed macrocytic normochromic anemia, and ultrasound showed a homogeneous hyperechoic pattern in the udder parenchyma. Based on these examinations, the ewe was diagnosed with clinical mastitis. treatmentsment administered to the ewes included antibiotics, anti-inflammatory agents, and antipyretics, followed by flushing the udder with normal saline and intramammary antibiotic administration. One week treatment appeared to reduced the symptoms of clinical mastitis, but further care is needed to achieve a full recovery
A Case Study: The Behavior of A Primparous Etawa Crossbreed Goat That Refuse to Nurse Its Kid As A Risk Factor To Clinical Mastitis Mira Fatmawati; Putri, Desinta Dwi Melati
Veterinary Biomedical and Clinical Journal Vol. 8 No. 1 (2026): Vol. 8 No. 1 2026
Publisher : Faculty of Veterinary Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.VetBioClinJ.2026.008.01.5

Abstract

Clinical mastitis is an inflammatory response of the mammary gland tissue that can be caused by physical trauma or microbial infection. A predisposing factor in this case is the natural behavior of a primiparous goat that is not yet accustomed to nursing its kid. The objective of this case study was to identify the predisposing factors, clinical signs, diagnosis, and treatment of clinical mastitis in goats. In this case report, a 1.5-year-old Etawah crossbred doe was presented by the owner with complaints of anorexia and refusal to nurse its offspring. The doe had given birth three months prior and was primiparous. Physical examination of the udder revealed swelling of the left udder quarter and a pain response upon palpation. Diagnostic confirmation was performed using the California Mastitis Test (CMT) and milk pH examination. The CMT result of milk collected from the left udder quarter was positive. The milk pH examination of the same quarter showed a pH of 8, indicating an alkaline condition. Based on these findings, the goat was diagnosed with clinical mastitis. The treatment administered consisted of antibiotics, anti-inflammatory drugs, and antipyretics. Management of the kid from the primiparous doe was carried out by providing a milk replacer with assistance from the farmer. Meanwhile, the doe was milk-stripped regularly to prevent the occurrence of clinical mastitis due to milk accumulation in the udder.
An Incidence of Repeat Breeding in Female Bali Cattle (Bos sondaicus) in Bayan District, North Lombok, Indonesia Farizi, Dicki Al; Kholik; Lovela, Aprinda Ratna; Mudhita , Ida Ketut
Veterinary Biomedical and Clinical Journal Vol. 8 No. 1 (2026): Vol. 8 No. 1 2026
Publisher : Faculty of Veterinary Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.VetBioClinJ.2026.008.01.4

Abstract

Repeat breeding is one of the reproductive disorders that can reduce reproductive efficiency and productivity in cattle, including female Bali cattle (Bos sondaicus). Bayan District, North Lombok Regency, is an area with a relatively high population of Bali cattle, where repeated pregnancy failure following artificial insemination has still been reported. This study aimed to determine the incidence of repeat breeding in female Bali cattle in Bayan District, North Lombok, Indonesia. The study was conducted using a survey method with a quantitative descriptive approach. The research sample consisted of 68 multiparous female Bali cattle aged 3–7 years, selected using purposive sampling. Primary data were obtained through field observations and interviews with farmers, while secondary data were collected from artificial insemination records available at the UPTD of the Department of Food Security, Fisheries, and Agriculture of Bayan District, North Lombok. Repeat breeding was defined as a condition in which female cattle failed to conceive after three or more inseminations or matings. The results showed that 13 female Bali cattle (19.1%) experienced repeat breeding, while 55 cattle (80.9%) successfully conceived. These findings indicate that the incidence of repeat breeding in female Bali cattle in the study area is categorized as moderate and may potentially reduce reproductive efficiency if not properly managed. Therefore, continuous monitoring of reproductive performance and improvement of reproductive management are necessary to reduce the incidence of repeat breeding and enhance the productivity of Bali cattle.

Page 8 of 8 | Total Record : 78

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