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INDONESIA
Jurnal Pembelajaran dan Biologi Nukleus
Published by Universitas Labuhanbatu
ISSN : 24429481     EISSN : 26857332     DOI : https://doi.org/10.36987/jpbn
Core Subject : Science, Education, Agriculture, Social,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Environmental Science Immunology & microbiology Languange, Linguistic, Communication & Media
Jurnal Pendidikan Biologi merupakan jurnal elektronik yang merupakan wadah penerbitan artikel penelitian original yang terkait dengan penelitian pendidikan biologi. Jurnal ini dikelola oleh Program Studi Pendidikan Biologidibawah naungan LPPM Universitas Labuhanbatu. Jurnal ini diterbitkan dua kali dalam setahun pada bulan Maret dan September. Jurnal ini menyajikan hasil penelitian dibidang Pendidikan Biologi dan sains Biologi.
Arjuna Subject : Biokimia, Genetika dan Biologi Molekuler - Biokimia, Genetika dan Biologi Molekuler (Lain-Lain)
Articles 472 Documents
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Phytochemical Profiling and Hemostatic Potential of Iris domestica Fruit Extract for Wound Bleeding Control Jon Kenedy Marpaung; Manuppak Irianto Tampubolon; Adiansyah Adiansyah
JURNAL PEMBELAJARAN DAN BIOLOGI NUKLEUS Vol 12, No 1: Jurnal Pembelajaran Dan Biologi Nukleus March 2026
Publisher : Universitas Labuhanbatu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36987/jpbn.v12i1.8460

Abstract

Background: Uncontrolled bleeding remains a major challenge in wound care, particularly in emergency and resource-limited settings. Limitations of synthetic hemostatic agents, including high cost, side effects, and limited access, have driven interest in plant-based alternatives. Iris domestica contains bioactive metabolites with astringent and wound-healing properties. This study aimed to characterize its phytochemical constituents and assess the hemostatic activity of its fruit extract. Methodology: Phytochemical screening was conducted on powdered simplicia, ethanol extract, and solvent fractions (n-hexane, ethyl acetate, and aqueous). Antibacterial activity was evaluated using the agar well diffusion method against Gram-positive and Gram-negative bacteria. Hemostatic activity was assessed through in vitro clotting time and in vivo bleeding time assays in rodents, grouped into negative control (saline), positive control (standard agent), and extract-treated groups at varying concentrations. Data were analyzed using one-way ANOVA with Tukey’s post hoc test (p < 0.05). Findings:  Phytochemical analysis showed that the ethanol extract and ethyl acetate fraction contained alkaloids, flavonoids, glycosides, saponins, and tannins, with no triterpenoids detected. The ethanol extract exhibited dose-dependent antibacterial activity, with the highest inhibition against Staphylococcus aureus (12.70 mm at 250 mg/mL). Hemostatic assays revealed significantly reduced clotting and bleeding times compared to the negative control (p < 0.05), with activity comparable to the positive control, indicating strong hemostatic potential. Contributions: I. domestica fruit extract exhibits significant hemostatic activity, likely mediated by tannins via protein precipitation and vasoconstriction, with synergistic contributions from alkaloids and saponins. The inclusion of appropriate controls strengthens this evidence. These findings highlight its potential as a natural alternative to conventional hemostatic agents and warrant further bioassay-guided isolation and safety evaluation.
Optimizing Students’ Communication Skills through Kahoot-Assisted Project Based Learning in Biology Learning Sonia Sumiarti Gurning; Miswandi Tendrita; Erfina Erfina; Sutriani Kaliu
JURNAL PEMBELAJARAN DAN BIOLOGI NUKLEUS Vol 12, No 2: Jurnal Pembelajaran Dan Biologi Nukleus June 2026
Publisher : Universitas Labuhanbatu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36987/jpbn.v12i2.9431

Abstract

Background: Preliminary observations at SMAN 1 Wundulako Senior High School indicated that students had limited communication skills during biology learning because classroom instruction tended to be teacher-centered and provided insufficient opportunities for active interaction. Therefore, an innovative learning model such as Project-Based Learning supported by Kahoot is needed to enhance student engagement and optimally develop communication skills. Methodology: This research adopted a quantitative approach through a quasi-experimental method employing a posttest-only control group design. The participants consisted of 60 tenth-grade students at SMAN 1 Wundulako, with one class assigned as the experimental group and the other as the control group. Data were collected using a communication skills observation sheet, content-validated by two experts, measuring four indicators expressing and responding to opinions, mastery of presentation material, presenting findings clearly and systematically, and language use. Data were analyzed using an independent-samples t-test at a significance level of 0.05. Findings: Kahoot was integrated into the Project-Based Learning process as an interactive formative assessment tool. The findings demonstrate that PjBL integrated with Kahoot produced a statistically significant improvement in students' communication skills (p < 0.05), with the experimental group achieving a higher mean score (89.37) than the control group (50.83). Contribution: This learning model is capable of enhancing communication skills through collaborative activities, project presentations, and interactive quiz-based interactions. Thus, PjBL supported by Kahoot is effective as an innovative learning alternative for improving students’ communication skills. This study contributes to biology education by providing empirical evidence that integrating Kahoot into Project-Based Learning offers an effective technology-supported strategy for enhancing communication skills in senior high school biology classrooms

Page 48 of 48 | Total Record : 472

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