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Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua Jalan Besar Deli Tua No. 77, Kabupaten Deli Serdang, Sumatera- Utara
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INDONESIA
Jurnal Penelitian Farmasi dan Herbal
Published by INSTITUT KESEHATAN DELI HUSADA DELI TUA
ISSN : -     EISSN : 26547619     DOI : 10.36656/jpfh
Core Subject : Health,
Medicine & Pharmacology
Aims and Scope The Pharmaceutical & Herb Research Journal is a scientific journal published by Institut Kesehatan Deli Husada which publishes research journals in the field of pharmacy. Indonesia has a lot of natural resources that have the potential to have pharmacological effects. This journal is a place for researchers in the field of pharmacy to be able to publish their researches in 2 main areas, namely Pharmacy and Herbs In the Pharmacy area, accepted research articles include: • Pharmaceutical Biology • Pharmaceutical Chemistry • Pharmacology • Pharmaceutical Technology While the Herb area includes • Herb medicinal formulations from natural ingredients The Pharmaceutical & Herb Research Journal can also be a forum for informations and sources of knowledge related to the field of pharmaceutical science and herb medicine in Indonesia.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 193 Documents
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STUDI ETNOBOTANI TANAMAN OBAT SEBAGAI PENCEGAH STUNTING OLEH MASYARAKAT WALI NAGARI SIJUNJUNG KABUPATEN SIJUNJUNG, SUMATERA BARAT Relin Yesika
Jurnal Penelitian Farmasi & Herbal Vol 5 No 2 (2023): JURNAL PENELITIAN FARMASI & HERBAL
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v5i2.1201

Abstract

Stunting is the impaired growth and development that children experience from poor nutrition, repeated infection, and inadequate psychosocial stimulation. Children are defined as stunted if their height-for-age is more than two standard deviations below the WHO Child Growth Standards median. Malnutrition that occurs during pregnancy can lead to stunting which usually appears after the baby is 2 years old. One of the efforts to prevent stunting is consuming a balanced nutritious diet. Many plants and herbs have good nutritional value that can prevent stunting. Plants that have nutritional value can be processed into food that can prevent stunting. This research is a qualitative descriptive method, research has been carried out with the stages of compiling research objectives, observations, interviews, documentation. This research was carried out to answer the need for information related to plant data used to prevent stunting by the community in Wali Nagari, Sijunjung Regency, West sumatera. There were 41 residents in Wali nagari as respondents. The plants most commonly used by the community in Wali Nagari as stunting prevention plants are cassava leaves, spinach leaves, legumes or nuts, katuk leaves, aromatic ginger, kelor leaves, temulawak, pegagan or gotu kola leaves, etc
FORMULASI DAN UJI EFEKTIVITAS SEDIAAN KRIM EKSTRAK DAUN KELOR (Moringaoleifera) TERHADAP PENYEMBUHAN LUKA BAKAR PADA TIKUS PUTIH JANTAN (Rattus novergicus) Rani Ardiani
Jurnal Penelitian Farmasi & Herbal Vol 5 No 2 (2023): JURNAL PENELITIAN FARMASI & HERBAL
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v5i2.1212

Abstract

Burns are iinjuries ito ithe iskin ior iother iorganic itissue imainly icaused iby iheat ior idue ito iradiation, ifriction ior icontact iwith ichemicals. i iOne iof ithe iplants ithat ihave ithe ipotential ias ia iburn itreatment iis iMoringa ileaves. i iIn iMoringa i(Moringaoleifera) ileaves, iflavonoid ichemical icompounds ican iact idirectly ias iantibiotics iby iinterfering iwith ithe ifunction iof imicroorganisms isuch ias iburns. Objective to idetermine ithe imost ieffective iconcentration iof iMoringa i(Moringaoleifera) ileaf iethanol iextract ifor ihealing iburns iin imale iwhite irats. Methodirats ithat ihave ibeen ianesthetized iwith ilidocaine imuscularly. i Wounds iin rats iwere imade iby iattaching ia iheated i1 ix i1 icm istainless iplate. i iOn ithe ibacks iof irats iwhose ifur ihas ibeen ishaved iand iaffixed ito ithe iplate ifor i30 iseconds ito iform iblisters ior iburns, ithen ithe ipositive icontrol iconcentration igroup iis iapplied iwith ibioplacenton, ithe inegative icontrol iis ismeared iwith icream ibase, iand ithe itest igroup iis ismeared iwith iconcentrated iMoringa ileaf iextract icream i5%, i10% iand i.15%. i iThe ismearing iof iall itreatment igroups iwas icarried iout ievenly i3 itimes ievery iday, iobserving ichanges iin iburns ifor i14 idays. \ Results ithere iwas ia ireduction iin iburn ilength iat ieach iconcentration. i iThe ipositive icontrol ishowed ithe ifastest ireduction ievery iday ibecause iit icontained placenta extract and neomycin sulfate, in the negative control the wound healing was quite long from the wound diameter because it only used a cream base that did not contain nutritious substances. And at a concentration of 15% faster in the wound healing process. Conclusion:Moringa leaf ethanol extract at a concentration of 15% was the most effective in healing burns in male white rats compared to concentrations of 5% and 10%.
FORMULASI SEDIAAN GEL EKSTRAK ETANOL UMBI DAHLIA ( Dahlia variabilis )TERHADAP PERTUMBUHAN BAKTERI Stapylococcus aureus PENYEBAB INFEKSI KULIT Zola Efa Harnis
Jurnal Penelitian Farmasi & Herbal Vol 5 No 2 (2023): JURNAL PENELITIAN FARMASI & HERBAL
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v5i2.1214

Abstract

Dahlia tubers (Dahlia variabilis) are plants that are often found in the higglands. The content in Dahlia tubers is able to inhibit microbial growth. The compound content of Dahlia tubers includes alkaloids, flavaanoids, sapnonins and tannins. One of the diseases caused by microbes is a skin infection. The purpose of this study was to make a gel preparation from the ethanolic extract of dahlia bulbs and to test whether the formulation was able to inhibit the growth of Stapylococcus aureus bacteria at concentrations of 4%, 6% and 8%. The extraction used in this research is the maceration method with 96% ethanol as solvent. Evaluation test of gel preparations and antibacterial activity test by discdiffusion method. Then the one way ANOVA test was carried out. The results showed different result in each formulation. Based on the average results of the antibacterial activity test, the inhibition zones of F) were 17,0 mm, F1 18,13 mm, F2 was 19,73 mm, and F3 8,23 mm. The results of this study conuluded that the extraction of Dahlia tubers had antibacterial activity due to the presence of an inhibitory zone around the paper disc in a petri dish. Further research needs to be done with other methods.
PENENTUAN KANDUNGAN ANTIOKSIDAN DAN FENOLIK TOTAL DARI EKSTRAK TUMBUHAN SEBAGAI BIOREDUKTOR DALAM PEMBENTUKAN NANOPARTIKEL PERAK Dini Hanifa; Refilda Refilda; Akmal Djamaan
Jurnal Penelitian Farmasi & Herbal Vol 5 No 2 (2023): JURNAL PENELITIAN FARMASI & HERBAL
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v5i2.1226

Abstract

The formation of metal nanoparticles (silver, gold, platinum) by biological methods (green synthesis) has advantages over chemical and physical methods because it is easier, faster, simpler, and environmentally friendly. One of the substances used in this method is plant extracts. The presence of secondary metabolites that act as antioxidants such as phenolics and flavonoids play roles in the formation of silver nanoparticles. In this study, phytochemical screening was carried out from several herbal plants as bioreductors in the formation of silver nanoparticles, such as Phyllanthus buxifolius, Pachira aquatica, Peperomia pellucida, Ageratum conyzoides, and Piper crocatum leaf extracts. The total antioxidant content was determined using the modified phenanthroline method, and the total phenolic content determined using the Folin-Ciocalteu method. The formation of silver nanoparticles was carried out by mixing silver nitrate solution with each plant extract. Colloidal silver nanoparticles formed were then measured for their absorption spectra. The results of the antioxidant content of the five consecutive samples were 26,90 ± 0,19; 26,09 ± 0,14; 18,25 ± 0,02; 42,76 ± 0,14; dan 30,94 ± 0,14 mg AA/g, while the total phenolic contents were 48,44 ± 0,45; 21,08 ± 0,92; 17,42 ± 0,27; 57,71 ± 0,47; dan 49,83 ± 0,60 mg GA/g. Silver nanoparticles mediated by Ageratum conyzoides leaf extracts provided the highest absorbance value compared to other plants. The antioxidants and phenolic contained in the extract acts as reducing agent from silver ions into silver nanoparticles.
FORMULASI SEDIAAN HAIR TONIC EKSTRAK ETANOL DAUN TEH HIJAU (Camellia sinensis L.) SEBAGAI PENUMBUH RAMBUT TERHADAP KELINCI JANTAN (Oryctolagus cuniculus) Sembiring, Pintata
Jurnal Penelitian Farmasi Dan Herbal Vol 6 No 2 (2024): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v6i2.1240

Abstract

Background: hair loss is less or more hair than normal, with or without visible thinning. Green tea leaf minoxidil, whixh contains flavonoid compounds that may prevent hair loss, can be used to treat hair loss. Objective: this study aims to confirm whether green tea leaf ethanol extract can be used as a hair restorer that meets the requidments of physical stability, and to investigate the efficacy of green tea leaf extract hair restorer compared with minoxidil on hair growth purpose. Methods: This study used an experimental method that was macerated using 96% ethanol as a solvent. The formula was made into 3 concentrations, namely 2.5%; 5%; 7.5% compared with the drug minoxidil as a positive control. The three formulas were first evaluated to meet the requirements for hair tonic stability, then the hair effectiveness test was carried out with the test animal being a male rabbit. Results: the group that had the highest effectiveness on hair growth in rabbits was minoxidil which had an average value on the 7th, 14th and 21st days of 4.9 ; 6.3 ; 7.9 followed by the third formula which has a concentration of 7.5% as much as 4.5; 5.2 ; 6.5. While the negative control which was only applied with a hair tonic base only had hair growth 1,4; 1,9 ; 2,3. Conclusion: The preparation of hair tonic formula 1 to formula 3 met the requirements for physical stability, namely, pH test, viscosity test and organoleptic test. The preparation of hair tonic ethanol extract of green tea leaves (Camellia sinensis L.) showed that the 7.5% concentration was more effective in accelerating hair growth compared to formulas 1 and 2, and also showed that the 7.5% concentration had almost the same effectiveness as minoxidil (positive control).
The FORMULATION AND ACTIVITY TEST OF GEDI LEAF (Abelmoschus manihot L.) ANTI-ACNE GEL ETHANOL EXTRACT ON Staphylococcus aureus IN VITRO Suleman, Abdul Wahid
Jurnal Penelitian Farmasi & Herbal Vol 6 No 1 (2023): JURNAL PENELITIAN FARMASI & HERBAL
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v6i1.1254

Abstract

Gedi leaves (Abelmoschus manihot L.) have compounds such as flavonoids, saponins, tannins, and terpenoids which are useful as antibacterials, such as the treatment of acne and other diseases. This research method was carried out in a laboratory experiment, namely gedi leaf extract was made in the form of a gel preparation with a concentration of negative control, FI (2.5%), FII (5%), FIII (7.5%) . Then proceed with the evaluation of the preparation with the organoleptic test, homogeneity test, pH test, spreadability test, adhesion test, viscosity test, and Cyling test. Antibacterial activity testing was carried out using the well method. The results of this study indicate that the ethanol extract of gedi leaves can be formulated as an anti-acne gel preparation that is physically and chemically stable. In the antibacterial test, the inhibition zone formed in formula 1 (2.5%) was 10,7±0,95 mm, in formula 2 (5%) the inhibition zone formed was 15,6±0,86 mm and in formula 3 (7.5%) was the concentration which has the most optimal antibacterial activity against Staphylococcus aureus bacteria with an inhibition zone area of 18,8±0,70 mm. Conclusion: Gedi leaf ethanol extract anti-acne gel preparation can inhibit Staphylococcus aureus bacteria most effective at a concentration of 7.5%, namely 18,8±0,70 mm
ANALISIS KANDUNGAN KAFEIN PADA MINUMAN KOPI SIAP SAJI MENGGUNAKAN METODE KROMATOGRAFI LAPIS TIPIS-GAMBAR DIGITAL Rahayu, Ni Luh Ika; Fernanda, M.A. Hanny Ferry
Jurnal Penelitian Farmasi & Herbal Vol 6 No 1 (2023): JURNAL PENELITIAN FARMASI & HERBAL
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v6i1.1449

Abstract

Caffeine is a colorless, crystalline powder that has a slightly bitter taste. One of them is ready-to-drink coffee, which can help increase concentration and is much loved. This study aimed to develop a semi-qualitative analysis of caffeine compounds in ready-to-drink coffee using the TLC method. The mobile phase used was methanol: ethyl acetate: acetic acid (3:1:6) with a saturation time of the mobile phase in the chamber of 20 minutes, and the stationary phase used silica gel 60 F254. The results obtained have a linearity (r) of 0,991413. As for the caffeine content in ready-to-drink coffee brand A was 99,37 mg; brand B was 144,81 mg, and brand C was 96,42 mg. It can be concluded that digital image processing using the semi-quantitative TLC method of ready-to-drink coffee contains positive caffeine compounds
UJI EFEKTIVITAS EKSTRAK ETANOL DAUN BANDOTAN (Ageratum conyzoides) SEBAGAI ANTIDIARE Sembiring, Pintata
Jurnal Penelitian Farmasi & Herbal Vol 6 No 1 (2023): JURNAL PENELITIAN FARMASI & HERBAL
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v6i1.1507

Abstract

Diarrhea is an abnormal stool that is thinner than usual and occurs more than three times a day. Bandotan leaves have antibacterial properties. This study was an experimental study using 25 rats induced with oleumricin and divided into five groups, the negative control group of 1% CMC- Na, the positive control of Loperamide HCl and the group of bandotan leaf ethanol extract doses of 100 mg/kg, 150 mg/kg and 200 mg/kg. Bandotani leaves (Ageratum conyzoides) as samples were extracted by soaking using 96% ethanol then concentrated by spinning. The results of the phytochemical screening of bandotan leaves obtained flavanoid compounds, saponins, tannins, alkaloids. The results of the anti-diarrhea effect with EEDB doses of 100, 150 and 220 mg/kg showed an anti-diarrhea effect in male rats, the best anti-diarrhea effect was the average EEDB dose of 150 mg/kg. compared doses of 100 and 150 mg/kg. Bandotani leaf extract (Ageratum conyzoides) has antidiarrheal activity induced by oleumricin in male white rats.
REVIEW PENGARUH PENGGUNAAN SURFAKTAN PADA KARAKTERISTIK SEDIAAN ORODISPERSIBLE FILM (ODF) OBAT BERKELARUTAN RENDAH DALAM AIR: SIFAT DISINTEGRASI DAN DISOLUSI Nining, Nining
Jurnal Penelitian Farmasi & Herbal Vol 6 No 1 (2023): JURNAL PENELITIAN FARMASI & HERBAL
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v6i1.1516

Abstract

Orodispersible film (ODF) is a drug delivery gaining widespread acceptance because it disintegrates quickly and can be self-administered. ODF has the advantage of increasing the active pharmaceutical ingredient (API) effectiveness by rapid dissolution in the oral cavity after direct contact with saliva. One of the components of ODF that influences the physical characteristics and dissolution of low-soluble drugs in water is surfactant. This material acts as a wetting or dispersing agent so the film can quickly disintegrate and release API. The method used is searching for international journal data using the Google Scholar. The surfactants reported to have been used in the ODF formulation are L-arginine, poloxamer 407, tween 80, and sodium dodecyl sulfate. In general, surfactant usage significantly affects the disintegration behavior of the film and API release. This behavior is caused by reducing the interfacial tension between phases by surfactants, which causes increased solid surface wetting and helps speed up the film disintegration and API dissolution from the ODF matrix. The conclusion is that surfactant usage with the appropriate type and concentration will help improve the ODF quality, especially in the disintegration properties of the dosage form and API dissolution.
GAMBARAN UMUM PASIEN RAWAT JALAN DI RUMAH DAN EVALUASI PELAYANAN INFORMASI OBAT DI INSTALASI FARMASI RUMAH SAKIT UMUM SEMBIRING DELI TUA Syafitri, Anggun; Marbun, Viktor Edyward
Jurnal Penelitian Farmasi & Herbal Vol 6 No 1 (2023): JURNAL PENELITIAN FARMASI & HERBAL
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Drug Information Service (PIO) is one of the standards that must be applied to improve the best pharmaceutical services. Drug information services are very necessary for patients because complete drug information can determine the success of self-therapy at home, especially for outpatients. Provision of drug information has an important role to achieve optimal treatment results, Provision of drug information has an important role to achieve optimal treatment results, so as to improve the quality of life of patients. Pharmaceutical services at this time have shifted their orientation from drugs to patients referring to pharmaceutical care. This study used a descriptive observational research method with a cross sectional design and used a quantitative approach. This research was conducted at the Outpatient Installation of Sembiring Deli Tua General Hospital. The population is the entire object used in the study.

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