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Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua Jalan Besar Deli Tua No. 77, Kabupaten Deli Serdang, Sumatera- Utara
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Jurnal Penelitian Farmasi dan Herbal
Published by INSTITUT KESEHATAN DELI HUSADA DELI TUA
ISSN : -     EISSN : 26547619     DOI : 10.36656/jpfh
Core Subject : Health,
Medicine & Pharmacology
Aims and Scope The Pharmaceutical & Herb Research Journal is a scientific journal published by Institut Kesehatan Deli Husada which publishes research journals in the field of pharmacy. Indonesia has a lot of natural resources that have the potential to have pharmacological effects. This journal is a place for researchers in the field of pharmacy to be able to publish their researches in 2 main areas, namely Pharmacy and Herbs In the Pharmacy area, accepted research articles include: • Pharmaceutical Biology • Pharmaceutical Chemistry • Pharmacology • Pharmaceutical Technology While the Herb area includes • Herb medicinal formulations from natural ingredients The Pharmaceutical & Herb Research Journal can also be a forum for informations and sources of knowledge related to the field of pharmaceutical science and herb medicine in Indonesia.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 193 Documents
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HUBUNGAN PENGETAHUAN DAN SIKAP MASYARAKAT KECAMATAN CAKUNG JAKARTA TIMUR TERHADAP PENGGUNAAN DAN RESISTENSI ANTIBIOTIK Rusdi, Numlil Khaira; Hastuti, Septianita Hastuti; Maifitrianti, Maifitrianti; Nurhasnah, Nurhasnah; Azizah, Rahma Nur
Jurnal Penelitian Farmasi Dan Herbal Vol 6 No 2 (2024): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v6i2.1748

Abstract

Antibiotic resistance is one of the serious problems that are being faced today. Low levels of knowledge and poor public attitudes about antibiotic use can trigger resistance. This study aims to determine the level of knowledge, attitudes, and relationships between the level of knowledge and attitudes of the community about antibiotic use and resistance in Cakung District, East Jakarta for the July-August 2023 period. The design of this study was descriptive with cross sectional method. The sampling technique uses purposive sampling. The source of data in this study is primary data in the form of knowledge questionnaires and attitudes about antibiotics. Knowledge is categorized with high and low, while attitude is categorized with positive and negative. The results showed that as many as 400 respondents met the inclusion and exclusion criteria. The characteristics of public knowledge about antibiotics showed that 65.3% of respondents had high knowledge and 34.7% had low knowledge. As many as 61.0% of respondents had a positive attitude and 39% had a negative attitude towards the use of antibiotics and resistance. The results of the bivariate analysis showed that there was a significant relationship between the level of knowledge and people's attitudes towards antibiotic use and resistance (P<0.000). The higher the level of knowledge of the community, the more positive the attitude of the community towards the wise use of antibiotics.
FORMULASI SEDIAAN KRIM EKSTRAK ETANOL JAHE MERAH (Zingiber Officinalis var.Rubrum) SEBAGAI ANTIDIABETIC FOOT faradina, Anniza
Jurnal Penelitian Farmasi Dan Herbal Vol 6 No 2 (2024): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v6i2.1750

Abstract

Red ginger is used as a medicinal raw material because it contains 3% oleoresin which has anti-inflammatory, antioxidant, and anti-bleeding properties. In addition, red ginger contains volatile oil (2.58%-2.72%). Red ginger has long been used as medicine to treat a wide range of diseases, including preventing Staphylococcus aureus. Diabetic foot is caused by the pathogenic bacteria Staphylococcus aureus. The purpose of this study was to use experimental research to create a cream formula with ethanol extract of red ginger. Previous research shows that red ginger extract (Zingiber Officinalis Var. Rubrum) has an 80% inhibition zone of 13.11 mm against Staphylococcus aureus bacteria. It can be concluded that Formula 3 (propylene glycol 15%, TEA 3%, oleum rosae drops, cetyl alcohol 3%, and distilled water 50 ml) can be used to make red ginger ethanol extract cream as antidiabetic foot cream.
COMPARISON ANTIOXIDAN ACTIVITY OF RED GINGER (Zingiber officinale var. rubrum) ETANOL EXTRACTION BY MASERATION AND DIGESTI MASERATION METHODS Merry, Jesica
Jurnal Penelitian Farmasi Dan Herbal Vol 6 No 2 (2024): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v6i2.1760

Abstract

The red ginger plant (Zingiber officinale variety rubrum) is a common plant in our surroundings that is used to cure a number of degenerative diseases as well as pain management, antipyretic, and anti-inflammatory conditions. Volatile oil, non-volatile oil and starch substances are part of red ginger. The volatile oil or volatile oil gives ginger its characteristic odor, and the non-volatile oil or oleoresin gives it its bitter taste. Oleoresin, which consists of resin, gingerol, and shogaol, It is an antioxidant needed by the body to prevent free radicals from forming and being harmful to the body. The reason for this is to determine the antioxidant content of red ginger. The extraction methods used were maceration with the process of soaking the material using nonpolar solvents without heating and digestion maceration or kinetic maceration (continuous stirring) using weak heating at 40-50°C. Very strong antioxidant activity was obtained where digestion maceration with an IC50 value of 7,30 was stronger than maceration with an IC50 of 11,90 because heating in digestion maceration opens the tissue in red ginger so that active compounds are extracted out.
TESTING FOR ANTIBACTERIAL ACTIVITY OF FRUIT SKIN ETHANOL EXTRACT DUKU (Lansium domesticum Corr) AGAINST BACTERIA Salmonella Typhi Wulandari, Suci
Jurnal Penelitian Farmasi Dan Herbal Vol 6 No 2 (2024): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v6i2.1762

Abstract

Salmonella typhimurium bacteria is the cause of typhoid fever. One of the herbal plants that can be used as an antibacterial drug is duku fruit peel (Lansium domesticum Corr). Phytochemical tests were carried out on duku fruit peel extract which was soaked in 96% ethanol solvent. The aim of this test is to identify secondary metabolites found in duku fruit skin. There are alkaloids, flavonoids, saponins, tannins and triterpenoids in the ethanol extract of duku fruit peel. This study involved four treatment groups with extract concentrations of 25 percent, 50 percent, and 75 percent, along with a positive control (chloramphenicol) and a negative control (distilled water). With inhibition zone diameters of 10.22 mm, 11.94 mm, and 13 mm, the ethanol extract of duku fruit peel showed antibacterial activity against Salmonella enterica bacteria. The results of univariate data analysis showed that the ethanol extract of duku fruit peel showed antibacterial activity at 25%, 50% and 75%. The results of univariate data analysis showed that the ethanol extract of duku fruit peel showed antibacterial activity against Salmonella typhi bacteria. In addition, the bacterial concentration increases with the width of the inhibition zone.
FORMULASI DAN eval_UASI SEDIAAN SHAMPOO EKSTRAK ETANOL DAUN CENGKEH (Syzygium aromaticum) SEBAGAI PENUMBUH RAMBUT PADA TIKUS PUTIH Sembiring, Pintata
Jurnal Penelitian Farmasi Dan Herbal Vol 7 No 1 (2024): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v7i1.1943

Abstract

Daun Cengkeh (Syzygium aromaticum) memiliki khasiat untuk mengatasi permasalahan pertumbuhan rambut. Yang dimana senyawa yang terkandung didalam daun cengkeh adalah eugenol yang berkhasiat sebagai penumbuh rambut. Tujuan dari penelitian iniadalah mengetahui sebuah efektivitas dari suatu sediaan shampoo dengan menggunakan ekstrak etanol daun cengkeh sebagai pembantu dalam mengatasi rambut rontok, dengan menggunakan formula 10%, 20%, dan 30%. Ekstrak dibuat dengan metode perendaman menggunakan pelarut etanol 96%. Hewan uji pada penelitian rambut/bulu dicukur yang dimana akan diuji menggunakan 5 ekor tikus yang masing masing bulunya telah dicukur dengan ukuran 3x3 cm. Kelompok pertama (kontrol positif), kelompok kedua (kontrol negatif), kelompok ketiga (Shampoo Ekstrak Etanol Daun Cengkeh 10%), kelompok 4 (Shampoo Ekstrak Etanol Daun Cengkeh 20%) dan kelompok kelima (Shampoo Ekstrak Etanol Daun Cengkeh 30%). Parameter dalam penelitian ini adalah diameter sebagai pertumbuhan rambut. Hasil penelitian ini menunjukkan bahwa shampoo dari ekstrak etanol daun cengkeh dengan konsentrasi 30% adalah formulasi sediaan yang paling efektif dalam pertumbuhan rambut pada tikus jantan. Sediaan shampoo ekstrak etanol daun cengkeh kurang efektif dibandingkan dengan shampoo Clear pada pertumbuhan rambut.
Kajian Literatur: Aplikasi Sejumlah Metode Ekstraksi Konvensional untuk Mengekstraksi Senyawa Fenolik dari Bahan Alam Arrofiqi, Mochammad Rasyad; Sakti, Aditya Sindu; Mayangsari, Fransisca Dita
Jurnal Penelitian Farmasi Dan Herbal Vol 7 No 1 (2024): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v7i1.1972

Abstract

This literature review explores various conventional extraction methods utilized to extract phenolic compounds from natural materials. Phenolic compounds, known for their significant antioxidant, anti-inflammatory, and anticancer properties, are crucial bioactive molecules found in plants. The study examines methods such as maceration, percolation, reflux, Soxhlet, digestion, infusion, and decoction, highlighting their efficiencies, advantages, and limitations. The findings suggest that while conventional methods are cost-effective and accessible, they often require longer extraction times and may lead to thermal degradation of sensitive compounds
Diabetes UJI EFEKTIVITAS ANTIDIABETES KOMBINASI EKSTRAK ETANOL DAUN AFRIKA (Vernonia amygdalina) dan BUNGA ASOKA (Ixora paludosa) TERHADAP PENURUNAN KADAR GLUKOSA DARAH TIKUS YANG DIINDUKSI ALOKSAN Gultom, Evi Depiana
Jurnal Penelitian Farmasi Dan Herbal Vol 7 No 1 (2024): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v7i1.1981

Abstract

Diabeiteis meillitus is a diseiasei in which blood glucosei leiveils increiasei duei to damagei to pancreiatic ceill, meitabolic disordeirs and insulin reisistancei which can bei treiateid with traditional meidicineis deiriveid from plants. Onei eixamplei of a plant that can loweir blood glucosei leiveils is Afrika Leiaf and Asoka Floweir which contains flavonoids to loweir blood glucosei by increiasing ceill seinsitivity to insulin and stimulating insulin reileiasei in pancreiatic β ceills. To deiteirminei thei eiffeict of Afrika leaves and Asoka Floweir eixtract in loweiring blood glucosei leiveils compareid to glibeinclamidei. Expeirimeintal study using 25 rats induceid by alloxan and divideid into 5 groups. Group 1 (neigativei control) CMC Na 1%, group 2 (positivei control) glibeinclamidei dosei 0.45 mg/kg, group 3 Afrika leiaf and Asoka floweir eixtract dosei 100+50 mg/kgBB, group 4 Afrika leiaf and Asoka floweir eixtract dosei 200+100 mg/kgBB and group 5Afrika leiaf and Asoka floweir eixtract dosei 300+150 mg/kgBB. Extraction using maceiration meithod with 96% eithanol solveint. From thei reisults of thei study eiach treiatmeint group eixpeirieinceid a deicreiasei in blood glucosei leiveils. Of thei 5 treiatmeint groups, thei deicreiasei in blood glucosei leiveils that was comparablei to that of glibeinclamidei was thei Afrika Leiaf and Asoka Floweir eithanol eixtract group at a dosei of 300+150 mg/Kg BB.
Hiperlipidemia Uji Efektivitas Antihiperlipidemia Ekstrak Etanol Daun Kersen (Muntingia calabura L.) Pada Tikus Putih Jantan Yang Di Induksi Fruktosa Gultom, Evi Depiana
Jurnal Penelitian Farmasi Dan Herbal Vol 7 No 1 (2024): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v7i1.1985

Abstract

Hyperlipidemia is a condition of high lipid concentration which is characterized by increased concentrations of triglycerides, LDL (Low Density Lipoprotein), blood cholesterol that exceeds normal limits which is one of the risk factors for cardiovascular disease. Kersen leaf has contains secondary metabolites of flavonoids and saponins which are thought to reduce cholesterol levels in the blood. The aim of this study was to determine the antihyperlipidemic effectiveness of ethanol extract of kersen leaf (EEDK/EEKL) in fructose-induced male white rats. Testing the effectiveness of antihyperlipidemia was carried out using an experimental method using fructose-induced male rats as test animals. The test animals were divided into 5 groups, namely negative control (CMC Na 1%), positive control of simvastatin (0.9 mg/kgBB), EEDK dose of 350 mg/kgBB, EEDK dose of 400 mg/kgBB, EEDK dose of 500mg/kgBB. Cholesterol levels were measured using the point of care testing (POCT) method. The data obtained were analyzed statistically using the one way ANOVA test. The results of the analysis showed that there were significant differences between the negative control, positive control, EEDK 350 mg/kg, EEDK 400 mg/kg and EEDK 500 mg/kg (P<0.05). The decrease in cholesterol levels increased in line with the increase in the dose of cherry leaf ethanol extract. The most effective EEDK as antihyperlipidemia is the EEDK at a dose of 500 mg/kg BW. There was no significant difference between the positive control and the 500 mg/kg BW EEDK dose (P>0.05). Based on the results of the statistical analysis that has been carried out, it can be concluded that the ethanol extract of cherry leaves has an antihyperlipidemic effect on rats.
- KAJIAN PENGGUNAAN ANTIBIOTIK PADA Neonatus Intensif Care Unit DI RUMAH SAKIT UMUM SEMBIRING DELI TUA Rahmi, Sofia -
Jurnal Penelitian Farmasi Dan Herbal Vol 7 No 1 (2024): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v7i1.1997

Abstract

Infancy is the period after birth before 59 months of age. Death in infants can be caused by several things, and one of the biggest causes of death in infants is due to infection. increased risk of therapeutic failure, one of the impacts that need to be aware of is the potential for resistance when the antibiotics given cannot reach the minimum level to inhibit growth or kill bacteria. The occurrence of problems in NICU patients due to antibiotic use caused by antibiotic use. This research method is by collecting data obtained from medical records and families of patients treated at Sembiring Delitua General Hospital by observing the use of antibiotics for 28 days. The results obtained were several antibiotics, namely Cefotaxime, Gentamicin, Cefadroxil, Ampicillin, and Meropenem. The conclusion of this study is that the type of antibiotic used is cefotaxime, the results of the analysis of antibiotic suitability in patients who receive a diagnosis of infection are in accordance with the needs of the patient and have fulfilled the 4T1W criteria (right drug, right patient, right indication and alert side effects).
FORMULASI DAN UJI EFEKTIVITAS SEDIAAN EKSTRAK ETANOL KULIT PEPAYA (Carica papaya L) SEBAGAI BRIGHTENING GEL SERUM Syafitri, Anggun; Sianipar, Masria Phetheresia; Fantika, Ardhana
Jurnal Penelitian Farmasi Dan Herbal Vol 7 No 1 (2024): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v7i1.1998

Abstract

Facial skin problems that often occur in women and adolescents are dull skin and dark looking skin. Papaya peel (carica papaya L) contains flavonoid compounds which function as antioxidants to brighten the skin. This study aims to formulate papaya peel extract into a serum gel dosage form and observe its effectiveness on the skin of volunteers for 4 weeks of treatment. The research was started by making papaya peel extract which was obtained by maceration method. Then the extract was formulated into serum gel preparations with varying concentrations of gelling agent Carbomer 940 4%, 5%, 6%. The preparations were eval_uated for their physical characteristics, namely organoleptic test, pH test, spreadability test, viscosity test, homogeneity test, irritation test, and test volunteer. The results showed that papaya peel extract could be formulated into a serum gel preparation that was homogeneous, light brown in color, had a spreadability of <5 cm, with a pH <6, and had a viscosity of >2000 cps. Serum gel formula containing Carbomer 940 with a concentration of 6% which has the best effectiveness.

Page 15 of 20 | Total Record : 193

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