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Hotimah Masdan Salim, dr., Ph.D
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International Islamic Medical Journal
Published by Universitas Nahdlatul Ulama Surabaya
ISSN : 27162370     EISSN : 27162389     DOI : https://doi.org/10.33086/iimj
Core Subject : Religion, Humanities, Health,
Religion Humanities Health Professions Medicine & Pharmacology Public Health
The International Islamic Medical Journal (IIMJ) is the official journal of Faculty of Medicine, University of Nahdlatul Ulama Surabaya, Indonesia. It serves primarily as a forum for education and intellectual discourse for health professionals namely in clinical medicine but covers diverse issues relating to medical ethics, professionalism as well as medical developments and research in basic medical sciences (Anatomy, Histology, Physiology, Biochemistry and etc) . It also serves the unique purpose of highlighting issues and research pertaining to the Islamic medical in the world. IIMJ is an online journal published twice a year (June and December). This article should be written in academic English.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 103 Documents
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Case Study : Prognosis of Recurrent Depressive Disorder with Somatic Symptoms Laila, Firda Nur; Algristian, Hafid; Azizah, Nur
Jurnal Medis Islam Internasional Vol 5 No 1 (2023): December
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v5i1.4454

Abstract

Introduction: Depression is a common disease worldwide, with more than 264 million people affected. Especially if it lasts a long time and is of moderate or severe intensity, depression can be a serious health condition. Depression can cause affected people to suffer greatly and function poorly at work, at school, and in the family. At its worst, depression can lead to suicide. In general, the good prognosis of depressive episodes can be achieved as well as good response to treatment and early interventions, but with the absence of any other complication such as psychotic symptoms and somatic complaints. This paper discusses the prognosis of recurrent depressive disorders with somatic complaints through a case study. Case: Male 23 years old complained of headaches that did not improve with pain medication and often recurred for two weeks, feels tingling and heavy in the back, worsening at night, interfere with the patient's daily activities and sleep in the night. These depressive symptoms have recurred since the patient was 19 years old. The patient experienced repeated stress due to arguments between his parents who were often involved in verbal abuse. The patient's prognosis is analyzed using several aspects according to Maramis prognosis analysis, including age, premorbid personality, type of disorder, course of treatment, hereditary factors, and the presence/absence of precipitating factors. Discussion: According to the course of the disease, the patient experienced recurrent depression since the age of less than 20 years, with somatic symptoms currently accompanying his depressive disorder. The patient experienced repeated recurrences even though he was stated to have improved by the treating doctor, which indicates that the patient's stress management was inadequate. The patient is currently experiencing a skin disorder that worsens his pessimistic feelings and is receiving SSRI antidepressants to improve his depressive symptoms. Based on the analysis of the course of the disease, the prognosis for depressive disorders in patients is poor, or dubia ad bonam. Conclusions: Recurrent depressive disorders involving younger ages, complications such as somatic symptoms, suboptimal social support, inadequate coping mechanisms, will worsen the prognosis of depression even after receiving adequate treatment
Case Report: Ischaemic Stroke Presented with Hemichorea-Hemiballism Ariobimo, Bonfilio Neltio; Puspamaniar, Vania Ayu; Nujum, Nurun; Puspitorini, Lisa
Jurnal Medis Islam Internasional Vol 5 No 1 (2023): December
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v5i1.4911

Abstract

Introduction: Movement disorders can be separated into hypokinetic disorders, which cause paucity or slowness (bradykinesia), and hyperkinetic disorders, which cause excessive, aberrant involuntary motions Less than 5% of individuals with cerebrovascular diseases presented with involuntary movement. It might be difficult to identify and diagnose hyperkinetic disorders. Case: We describe a 56-year-old man who arrived at the hospital with 5 hours of abrupt, uncontrollable movement in his right upper and lower limbs. A complete neurological evaluation revealed an uncontrolled, nonrhythmic, non-patterned, aimless, and frequently jerky movement of the right upper and lower limbs with a ballistic component that varies in amplitude and frequency. Higher psychic function and cranial nerves were normal. Chest radiography, electrocardiography were normal. Hemorrhage was ruled out by a brain non-contrast CT scan at admission. The patient was diagnosed with hemichorea-hemiballism caused by an ischemic stroke based on clinical evidence of a sudden neurological deficit of aberrant involuntary movement. After receiving medical treatment for five days, the involuntary motions stopped occurring without causing any more neurological abnormalities or weakening. Discussion: Ischemic stroke diagnosis relied on skilled clinical assessment without explicit neuroimaging. While hemiballismus is characterized by violent irregular flinging movements of the limbs brought on by contractions of the proximal muscles, hemichorea consists of continuous random, anarchic, and jerking movements involving both the distal and proximal muscles (though it is occasionally localized more distally). Conclusion : Hyperkinetic movement disorders are a rare presentation of stroke. The pathophysiology of these abnormal movements remains uncertain. Even though they are uncommon, following a stroke, aberrant motions can occur suddenly or develop gradually. Hemichorea-hemiballismus with abrupt onset should be treated as an acute stroke unless proven other causes
Different Approaches to Islamic Medicine in Iran Jafari, Ali; Parizi, Mohammad Sohrabian
Jurnal Medis Islam Internasional Vol 5 No 1 (2023): December
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v5i1.4953

Abstract

Background: Subject and objectives: Using the capabilities of Islamic civilization is one of the topics that has attracted the attention of contemporary Islamic thinkers. In this context, various opinions have been presented about whether medicine is Islamic or not among Iranian thinkers. In this article, we seek to examine the negative and positive opinions about the nature of Islamic medicine. The purpose of this article is to find a precise definition of Islamic medicine and provide a correct solution in using this treatment model. Result: This research deals with the study of Islamic medicine through descriptive-analytical and documentary methods. In this research, a complete search of electronic banks, related books, and internet sites was conducted and all acceptable articles were reviewed completely and systematically. There are different views on the nature of Islamic medicine, each of which has looked at the issue from its own angle, some agree with it and some oppose it. Conclusion: Islamic medicine has very good capacities, although there are serious criticisms against it. Islamic medicine is a specialized science, and a common opinion should be reached about its limits and conditions, and a system should be designed and drawn for it. The revival of Islamic medicine will contribute to the development of the modern Islamic civilization.
Parasitic Disease and COVID-19 Syndemics in Indonesia: Biomedical Aspects Trasia, Reqgi First
Jurnal Medis Islam Internasional Vol 5 No 1 (2023): December
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v5i1.5068

Abstract

Background: Syndemics happened while two or more coinfections have dangerous interaction and lead to a harmful outcome than for either single infection. In Indonesia, during COVID-19 pandemic, it has deal with a doble burden presume to neglected tropical disese (NTD) control. Parasitic disease as a part of NTD must be a concern in Indonesia along pandemc. There are still few articles that review the biomedical aspects of co-infection COVID-19 with parasitic diseases in Indonesia, whereas an understanding of biomedical aspects can encourage knowledge about pathogenesis which will make an earlier diagnosis. Results: This review summarize how parasites may serve as protective agents or risk factors in pandemic and, vice versa, how the COVID-19 may disturb the prevention and misdiagnosis of parasitic disease in Indonesia. Co-infection COVID-19 with malaria increass the burden of severe clinical manifestations and poor prognosis due to exaggerated proinflammatory response. Coinfection triggers TNF and IL-6 to activate coagulation cascade leading to micro-thrombosis and coagulopathy. Besides, helminthiasis causes vary configuration of immune-modulation, thereby lowering susceptibility to other infections and tolerating COVID-19 better. They modify Th2 respons to limit pro-inflammatory cytokines, such as IL-6 which is observed in severe cases of COVID-19. T-cell hypoactivation in SARS-CoV-2 and W.bancrofti will cause  relatively mild manifestation of COVID-19. Conclusions: In parasite infection, the IL-4 may elevate and induce shadow memory CD8+ T-cell (TVM cell) for CD8 response rapidly agains virus. It control human IL-4 or IL-10 that leads to the maturation of Th2 cells and down-regulation of the inflamation respons of IFN-g, IL-17 and TNF-a. These mechanisms allow us to blockade the cytokines storms observed in COVID-19 cases.
Ethical Principles As Student Motivation Continuing Education At Medical Faculty, Nahdlatul Ulama University, Surabaya Sari, Paramita; Syarifah, Mustika Chasanatusy; Firdaus, Abraham Ahmad Ali
Jurnal Medis Islam Internasional Vol 5 No 1 (2023): December
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v5i1.5178

Abstract

Background : Ethics is an important component in human life to distinguish good and bad behavior. Motivation is very important when an individual wants to do something and decides something. Ethics supports a person's motivation to do things they think are good, including determining education at medical school. Objective : The research aims to find out students' thinking principles based on the science of ethics so that by knowing these thinking principles researchers can find out students' motivations in choosing and continuing their studies at medical faculty. Methods : This research is a quantitative study with a descriptive approach on all students of the Class of 2022 FK UNUSA. The survey used secondary data from student interviews from the new student admissions committee, data analysis using descriptive analytics and data validity using correlation tests. Result : The results of this research show that 81% of students have the principle of virtue ethic thinking, supported by Personal Characteristics Test data showing that 72% of students are advised to be accepted as students at the medical faculty. Conclusion : So, it can be concluded that virtue ethics is a motivation to continue education at the Faculty of Medicine, Nahdlatul Ulama University, Surabaya.
Case Report : Diagnosis and Management of Peripartum Cardiomyopathy Laksono, Sidhi; Puteri Nandifa, Veronica Nadya
Jurnal Medis Islam Internasional Vol 5 No 1 (2023): December
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v5i1.5202

Abstract

Introduction: Peripartum cardiomyopathy (PPCM) is generally viewed as diagnosis of exclusion in women presenting with heart failure and systolic dysfunction of unclear identifiable etiology. Etiology of PPCM is not fully understood and multifactorial. The purpose of this case is to review the diagnosis and management PPCM based on our experience in managing 31 years old woman with PPCM. Case: A 31 year old woman presented with dyspnea persisting for two days, exacerbated over the last 24 hours. She gave birth to her third child seven months ago. Patient had been experiencing dyspnea since 4 months earlier but seek no medical help. Upon physical examination, hemodynamic was stable, wet rales was noted in two thirds of the lung fields. Echocardiography revealed dilated left ventricle with eccentric hypertrophy and reduced ejection fraction (18%). Treatment was initiated with furosemide IV to resolve dyspnea, then Ramipril, bisoprolol, forxiga and spironolactone was given as heart failure therapy. Discussion: PPCM should be suspected in any peripartum women presenting with symptoms and signs of heart failure. Careful history taking and diagnostic testing especially echocardiography is important to help physicians determine the diagnosis. Conclusion: Treatment with medication adjusted for pregnancy and lactation may prevent adverse outcome, improve clinical symptoms and improve the overall cardiac functions. Long term follow up is important for patients with PPCM, since the optimal duration of medications after recovery is still unknown.  
Effect of Oral Administration of Mytragina Speciosa on Blood Ketone Level and Glomerular Histology in Streptozotocin Induced Diabetic Mice choirotussanijjah, Choirotussanijjah; Salim, Hotimah Masdan; Bintarti, Tri Wahyuni; Irawan, Danny
Jurnal Medis Islam Internasional Vol 6 No 1 (2024): June
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v6i1.5232

Abstract

Introduction: Diabetes mellitus is a chronic metabolic disease characterized by increased sugar levels that cause serious damage to various organs. Diabetic ketoacidosis is one of the complications of diabetes mellitus. It is characterized by a decrease in the patient's consciousness, increased blood sugar levels, and the presence of acidic ketone bodies. It is a serious condition that can cause a coma or even death. Mytragina Speciosa,  known as kratom, is a plant often found in Southeast Asia, including Indonesia. This herb is frequently used as a stimulant to treat fatigue and help improve productivity. Based on previous research, Mytragina Speciosa is rich in alkaloids, flavonoids, and phenols. These compounds are very useful for inhibiting the activity of α-glucosidase and lipase enzymes in the pancreas, so they have a potential effect on diabetes mellitus. However, there has been no research related to the administration of Mytragina Speciosa its effect on blood ketone levels and glomerular diameter. Objective: to determine whether there is an effect of Mytragina Speciosa on blood ketone levels and glomerular diameter in mice with a diabetes mellitus model. Methods: Hyperglycemia is induced by Streptozotocin. On the 14th day, the mice will be checked for hyperglycemia and blood ketone levels. Administration of Mytragina Speciosa begins on day 15 for 2 weeks. At the end of the second week, the mice will be checked for blood ketone levels using a special kit to detect ketone bodies. Furthermore, the glomerular diameter will also be assessed. Results: In this study, treatment for 2 weeks only caused an increase in blood sugar levels in mice, but did not cause an increase in blood ketone levels in the diabetes group or other treatment groups (p > 0.05). Histological preparation of the Glomerulus showed a decline in glomerular diameter. Conclusions: The administration of Mitragyna speciosa extract did not result in a significant increase in blood ketone levels in diabetic mice. Many factors are involved in increasing blood ketone. It is necessary to monitor ketone levels during treatment as well as have a longer treatment time to see the effect of Mitragyna speciosa on ketones
Correlation Between Knee Osteoarthritis Pain and The Ability to Perform Salat Aisyah; Pane, Rita Vivera; Ambarasari, Utami; Kartini, Yanis
Jurnal Medis Islam Internasional Vol 5 No 2 (2024)
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v5i2.5234

Abstract

Introduction: Osteoarthritis (OA) has affected approximately 303 million individuals worldwide, making it the second most rapidly increasing disease behind Rheumatoid Arthritis. OA is the leading cause of lower extremity disability amongst older adults with an estimated lifetime risk for knee OA being approximately 40% in men and 47% in women. Osteoarthritis affects the entire joint which has symptoms that could intense pain and discomfort, making it difficult to carry out typical routine activities. This, of course, will conflict with Muslims who are obligated to perform daily prayers or salat which is an obligatory component of the daily routine of Muslims that is performed in the same way at least five times a day. Objective: This study aimed to analyze the correlation between knee osteoarthritis pain and the ability to perform salat. Methods: The method used in this study is an analytic observational method with a random sampling technique which was involved by 57 respondents in total. The data obtained was collected from April to May and showed frequency and percentage. Determination of the correlation between Knee Osteoarthritis and The Ability to perform Salat is done by statistical analysis with chi-square test using the SPSS application. Results: The asymptotic value obtained was 0.238. The obtained asymptotic value is >0.05. Conclusions: It can be concluded that there is no significant correlation between knee osteoarthritis pain and the ability to perform salat movements.
Periodontitis as a Risk Factor of Preeclampsia in Pregnancy: A Scoping Review Ridho, Fiki Muhammad; Algifnita, Avina Oktaviani; Pramaztri, Naurah Nabilah; Laksono, Eko Puji; Allifiah, Bella Pardian Nur; Ahmad, Mahesa
Jurnal Medis Islam Internasional Vol 5 No 2 (2024)
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v5i2.5316

Abstract

Introduction: Preeclampsia (PE) is a pregnancy complication characterized by hypertension and proteinuria after 20 weeks of gestation. Although the causes of PE are still unclear, there are factors that play an important role in increasing the incidence of PE, namely periodontitis which has an impact on the systemic spread of pathogens and inflammatory mediators, causing adverse pregnancy outcomes. This scoping review aims to evaluate, identify and provide a deeper understanding of the relationship and possible mechanisms between periodontitis and increased PE in pregnant women. A literature search following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines was conducted in PubMed, ScienceDirect, Scopus, and Google Scholar until July 2023. In the end, 14 articles were included for review. Results: All of the included studies stated that periodontitis mostly affects pregnant women with PE, and periodontitis is believed to play a role in increasing the risk of PE through the mechanism of bacteremia due to periodontal pathogens translocating from the oral cavity to the placenta and through cytokines and inflammatory mediators produced by inflamed periodontal tissue, resulting in disruption of the placenta, further increasing the risk of PE in pregnant women. Conclusions: In conclusion, there is a significant increase in the incidence of PE in pregnant women who experience periodontitis. Future research to review the mechanisms by which periodontitis increases the risk of PE and to examine whether periodontitis treatment before and during pregnancy can prevent PE may be warranted.
Effect of Musical Therapy on Malondialdehyde Levels on Male Mice Brain Tissue Farindra, Irmawan; Muhammad, Akbar Reza; Algristian, Hafid; Rusdi, Warda Elmaida; Yuniati, Dyah
Jurnal Medis Islam Internasional Vol 5 No 2 (2024)
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v5i2.5318

Abstract

Introduction: An example of a non-pharmacological therapy that is currently being developed is music therapy. The serenity created from classical music and murottal therapy is good for therapy performance, accelerating the healing process, and also reducing stress level. Objective: The aim of this study was to examine the effects of classical music "Mozart" and Murottal Al-Qur’an therapy on mouse malondialdehyde levels Methods: This study used 24 male BALB/c strain mice (10-12 weeks), in a true experimental setting using the Post Test Only Control Group Design. Four groups of mice were created: K (control), P1 (murottal Al-Qur'an), P2 (classical music "Mozart"), and P3 (combination therapy). SPSS 24 was used to analyze the data with a significance P < 0.05 Results: According to study findings, the P2 group had the highest average malondialdehyde level meanwhile the lowest average malondialdehyde levels was found in Group P1. The test results showed no significant relationship (p = 0.213) Conclusions: The findings of this study showed that there was no significant correlation between malondialdehyde levels when "Mozart" classical music and Murrotal treatment were given. The group who received the classical music "Mozart" nevertheless, had higher malondialdehyde levels, according to the findings.

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