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Hotimah Masdan Salim, dr., Ph.D
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Faculty of Medicine, University of Nahdlatul Ulama Surabaya
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INDONESIA
International Islamic Medical Journal
Published by Universitas Nahdlatul Ulama Surabaya
ISSN : 27162370     EISSN : 27162389     DOI : https://doi.org/10.33086/iimj
Core Subject : Religion, Humanities, Health,
Religion Humanities Health Professions Medicine & Pharmacology Public Health
The International Islamic Medical Journal (IIMJ) is the official journal of Faculty of Medicine, University of Nahdlatul Ulama Surabaya, Indonesia. It serves primarily as a forum for education and intellectual discourse for health professionals namely in clinical medicine but covers diverse issues relating to medical ethics, professionalism as well as medical developments and research in basic medical sciences (Anatomy, Histology, Physiology, Biochemistry and etc) . It also serves the unique purpose of highlighting issues and research pertaining to the Islamic medical in the world. IIMJ is an online journal published twice a year (June and December). This article should be written in academic English.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 103 Documents
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Profile of Stroke Patients with COVID-19 at Rumah Sakit Islam Surabaya Jemursari, Indonesia Syifak, Shobihatus; Yuniati, Dyah; Surya, Prima Ardiansyah; Saffanah, Vena Saskia Prima
Jurnal Medis Islam Internasional Vol 4 No 2 (2023): June
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v4i2.4131

Abstract

Background: Stroke is the number one cause of death in Indonesia, in America stroke is also the number one cause of disability. In COVID-19, most patients experience mild to moderate respiratory symptoms, and need no specific treatment. However, in some patients with comorbidities such as cardiovascular, diabetes mellitus, chronic respiratory disease, and malignancy, it often gives serious manifestation. Objective: This study aimed to profile of stroke patients with COVID-19 at Rumah Sakit Islam Surabaya Jemursari, Indonesia. Method: The type of this research was observational retrospective research. We used all the stroke patient hospitalized at Rumah Sakit Islam Surabaya Jemursari from April to December 2020 that confirmed the diagnosis of COVID-19. We used the general data, data of clinical symptoms, blood pressure, head CT-scan findings, and laboratory findings the data of participants was collected. The data showed as number (frequency) and percentage. Results: The patient’s average age of 57 years, male was common; patients with hypertension were often seen in the comorbidities; ischemic strokes were by far the most prevalent form; subcortical regions were the most frequent location of stroke based on the CT scan. The results of head CT showed that 91.7% of patients had an ischemic stroke and 8.3% of patients had a hemorrhagic stroke. Conclusions: The stroke patients with COVID-19 and hospitalized at Rumah Sakit Islam Surabaya Jemursari, Indonesia have an average age of 57 year, and most of the patient was male. Comorbid hypertension was commonly observed in this study. Based on the type of stroke, ischemic was the most common manifestation and subcortical regions were the most frequent location.
Intracerebral Hemorrhage-Grading Scale (ICH-GS) Score as a Prognosis Prediction of Spontaneous Intracerebral Hemorrhage at Rumah Sakit Islam Surabaya Jemursari Aulia, Nurlisa Naila; Syifak, Shobihatus; Yuniati, Dyah; Alam, Ilham Putera; Surya, Prima Ardiansyah
Jurnal Medis Islam Internasional Vol 4 No 2 (2023): June
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v4i2.4153

Abstract

Background: Spontaneous intracerebral hemorrhage or hemorrhagic stroke is one of the leading causes of mortality and disability in Indonesia, but until now there is no specific therapy for this disease. The intracerebral hemorrhage (ICH) score is a widely used predictive tool for the prognosis of death 30 days after spontaneous intracerebral hemorrhage, but the intracerebral hemorrhage-grading scale (ICH-GS) score has a more specific interval to assess the prediction of the prognosis after intracerebral hemorrhage. Rumah Sakit Islam (RSI) Jemursari Surabaya has not carried out data collection related to the ICH-GS score with the outcome (death) of patients with spontaneous intracerebral hemorrhage, especially while still receiving hospital treatment. Objective: To identify the number of ICH-GS scores in patients with spontaneous intracerebral hemorrhage as a predictor of prognosis at RSI Jemursari Surabaya. Method: The type of this research is retrospective research. The population comprised of all patients with spontaneous intracerebral hemorrhage hospitalized at RSI Jemursari Surabaya in 2017-2019, with affordable population of all patients with spontaneous intracerebral hemorrhage diagnosed by a neurologist. Results: The data showed that 5.5% (6 people) had an ICH-GS score of 5; 38.2% (42 people) had an ICG-GS score of 6; 21.8% (24 people) had an ICH-GS score of 7; 20 % (22 people) had an ICH-GS score of 8; 5.5% (6 people) had an ICH-GS score of 9; 4.5% (5 people) had an ICH-GS score of 10; 3.6% (4 people) had an ICH-GS score of 11; and 0.9% (1 patient) had an ICH-GS score of 12. Conclusions: The results of the ICH-GS score can be used to facilitate communication both with fellow health workers and with the patient's family. Trend of the data showed that ICH-GS score is not consistent in showing the prognosis of spontaneous intracerebral hemorrhage (the smaller the ICH-GS score should have better prognosis than the higher score), while the information based only on volume and location can predict the prognosis more consistently`.
Proximate and Some Micronutrients (Zn, Se, Fe and I) Assessed in Goat Milk, and Cattle Milk in Sokoto, Nigeria Salah, Nura Maiakwai; Daji, Atiku Yari Dogon; Umar, Rilwanu; Umar, AI; Sarkingobir, Yusuf
Jurnal Medis Islam Internasional Vol 4 No 2 (2023): June
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v4i2.4275

Abstract

Background: Malnutrition, poverty, and information scarcity are some of the major issues affecting people in West African region. Thus, it is imperative to divulge nutritional information from a cheap and accessible food (the milk) in the region. Objective: This study aimed at performing a proximate and Zn, Se, Fe and I micronutrients determination in goat and cattle milk in Sokoto, Nigeria. Method: The concentrations of zinc, selenium, iron, iodine present in goat and cattle in Sokoto, Nigeria were determined using standard methods and materials of analytical grade.  Results: The result reveals (< 0.05) Zn, Se, Fe, and I in goat as follows: 9.10 ± 0.05 ppm, 2.32 ± 0.004 ppm, 10.5 ± 0.05 ppm and 7.8 ± 0.01 ppm. In cattle, the concentrations for Zn, Se, and Fe are: 5.12 ± 1.05 ppm, 1.13 ± 0.005 ppm, 9.5 ± 0.02 ppm, and 5.9 ± 0.02 ppm. The proximate values of moisture content, ash content, protein, and fat in milk collected from goat are as follows respectively: 90.21%, 0.56 %, 3.23%, and 2.44%. The proximate values in cattle milk are: 70.11%, 0.50%, 2.11%, 2.11% and 2.21% for water content, ash content, protein content, and fat content respectively. Conclusions: Thus, the goat milk contains higher proximate contents (such as fat, water, carbohydrate, and ash), Zn, Fe, and Se than the cow milk. It is imperative for the public to properly utilize milk for its nutritious benefits.  
Treatment Problems In Triple Negative Breast Cancer Fasril , Thira; Hilbertina, Noza; Elliyanti, Aisyah
Jurnal Medis Islam Internasional Vol 4 No 2 (2023): June
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v4i2.3951

Abstract

Background: Breast cancer ranks second on the list of common diseases worldwide. It causes many deaths in the United States and Europe, second only to lung cancer. Triple-negative breast cancer (TNBC) does not express Estrogen Receptor (ER), Progesterone Receptor (PR), and Human Epithelial Receptor (HER2). It represents 24% of new cases of all breast cancer, and its incidence increases yearly. TNBC is a hormone-resistant breast cancer, so no current standard therapy exists. This article aims to explore regimen-resistant and troubleshooting treatment responses in TNBC cases. The method of writing this article is a literature review of studies using the keywords triple-negative breast cancer treatment and regimen, which are limited to only the most recent articles, 2012-2022, using search engines from PubMed, Science Direct, and Google Scholar. Results: There is no definitive therapy for the triple-negative breast cancer subtype, in which the TNBC type has no target receptor. Chemotherapy is the SOC of TNBC for early stage treatment. For late-stage and relapsed TNBC, however, chemotherapy is no longer the first choice. Currently there is no standard chemotherapy regimen that can be given to patients who experience relapse after chemotherapy because they will have a short response and lead to metastases. Some studies have shown that chemotherapy gives a better response, but the prognosis of TNBC remains poor. TNBC has different responses to therapy. TNBC showed a good response to combination chemotherapy along with pembrolizumab, capecitabine, olaparib, and radiotherapy, compared to chemotherapy by itself. Surgical therapy, such as Breast-Conserving Surgery (BCS), does not improve better prognosis in TNBC patients. Conclusions: Combining pembrolizumab, olaparib, capecitabine, and radiotherapy with chemotherapy increased survival rates compared to chemotherapy only.
Epidemiological Review: Mapping Cases and Prevalence of Helminthiasis in Indonesia on 2020-2022 Trasia, Reqgi First
Jurnal Medis Islam Internasional Vol 4 No 2 (2023): June
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v4i2.4172

Abstract

Background: Helminthiasis cannot be separated from society in Indonesia. In 2020, the World Health Organization (WHO) classified helminth infections as neglected tropical diseases (NTD) that require large-scale control, because more than 23% of the world's population is infected with helminthiasis. In Indonesia, there are still few articles that comprehensively review the epidemiological mapping of the latest helminthiasis cases. The purpose of writing this article is to map the prevalence of helminthiasis in Indonesia in 2020-2022. This article is a systematic study  conducted from January-April 2023. The literature search was carried out through an electronic database. Result: The  findings of this study indicate that in the last three years, helminthiasis has not been eliminated in Indonesia. The  results of helminth species found to infest communities in several provinces in Indonesia include Ascaris lumbricoides, Trichuris trichiura, Hookworm, Hymenolepis nana, Taenia saginata, Taenia solium, Oxyuris vermicularis, Schistosoma japonicum, Strongiloides stercoralis, and Wuchereria bancrofti. The diagnosis of helminth infestation and infection is confirmed through microscopic examination by finding eggs, larvae, proglottids, and even adult worms that come out spontaneously through defecation. In addition, helminth transmission can occur through food contaminated with worm eggs. The government has tried to control helminthiasis through Permenkes number 15 of 2017 concerning Helminthiasis Management. However, the indicators of achieving the target of reducing the prevalence of intestinal worms to below 10% in each Regency/City as stated in Pasal 3 ayat 2 of the Permenkes have not been fully met. Conclusion: It can be seen in this study that there are still many provinces that have not reached the helminth control target. This condition is especially experienced by high-risk groups, such as children, mining workers, plantation workers, farmers, livestock workers, staff at slaughterhouses, and waste collectors.
Literature review: Vitamin D Levels and Perinatal Depression Association Dyaningratri Azzahra, Pingkan; Sawitri, Brihastami
Jurnal Medis Islam Internasional Vol 4 No 2 (2023): June
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v4i2.4366

Abstract

Background: Vitamin D levels have been linked to psychological symptoms such as anxiety, depression, and impaired cognitive performance. It is found that lower vitamin D levels in early pregnancy are associated with depressive symptoms in perinatal.This study examines the association between vitamin D levels and perinatal depression. This article based on literature source from Pubmed/MEDLINE and Science Direct with keywords: vitamin D levels including 25(OH)D levels or vitamin D deficiency, prenatal, antenatal, and postpartum depression. The discussion of this study will assist readers and health professionals analyze how vitamin D levels in the body affect the incidence of antepartum depression. Results: these are five filtered literature, the journal discusses the relationship between vitamin D levels and antepartum depression. This literature review shows that pregnant women with less than 20 ng/mL vitamin D levels are 3.3 times more at risk than pregnant women with more than 20 ng/mL. Vitamin D plays a role in the process of increasing serotonin synthesis and increasing anti-inflammatory so that it can suppress the increase in pro-inflammatory cytokines that play a role in the incidence of depression. Conclusion: There is a correlation between vitamin D levels and the occurrence of depression during the perinatal period. It can be suggested that pregnant women check their vitamin D levels regularly.
The Effect of Honey Administration on The Histopathology of The Duodenum of Wistar Rats as a Inhibition of The Toxic Effects of Borax (Sodium tetraborate) Noviana, Dian; Syarifah, Mustika Chasanatusy; Gumilang, Retna; Bintarti, Tri Wahyuni
Jurnal Medis Islam Internasional Vol 4 No 2 (2023): June
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v4i2.4445

Abstract

Background: Borax can result in oxidative stress and cause the onset of gastrointestinal ulcerations that will dampen the duodenal villi to become shorter and can even disappear. Cell damage due to oxidative stress can be prevented by administering antioxidants. Antioxidants will inhibit the onset of chain reactions in the formation of free radicals by complementing the existing electron deficiency. Honey is one of the natural ingredients that is rich in antioxidants and part of thibbun Nabawi as one of the inhibitors of the toxic effects of borax. Objective : The purpose of this study is to to analyze the effect of honey administration on the histopathological description of submucosa and epithelial mucosa of duodenal wistar rats as an inhibitor of the toxic effects of borax (Sodium tetraborate). Methods: This study used the true experimental method with Post Test Only Control Group Design using 25 mice which will be divided into five groups, namely K (negative control), P (positive control), M1 (borax and honey dose 1), M2 (borax and honey dose 2), M3 (borax and honey dose 3). This study was conducted for 22 days then. Took the duodenal organ on all samples and then made histological preparations with HE staining. Observations were made with an Olympus microscope to see submucosal edema and damage to the epithelium of the duodenal mucosa. Results: The results of the study found that borax 26 mg / head / day had an influence on the histopathological picture of duodenal borax. In addition, the administration of honey dose 75 mg / Kg BB provides a toxic inhibitory effect of borax in the duodenum best among other treatment groups. However, statistically there was no effect of honey administration on the histopathological picture of the duodenum of wistar rats as an inhibitor of the toxic effect of borax (Sodium Tetraborate) with p˃0.05. Conclusion: Statistically it can be concluded that there is no effect of  the administration of honey on the histopathology picture of the duodenum of wistar rats as an inhibitor of the toxic effects of borax (Sodium tetraborate).
Consanguinity via Breastfeeding in view of Islam and Science of Epigenetics Mahmood, Silvia
Jurnal Medis Islam Internasional Vol 4 No 2 (2023): June
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v4i2.4823

Abstract

Background : One of the unique features of the Qur´an and Sunna is that never contradict the Science. Quran is not considered as a scientific book, however, includes many extraordinary signs and true scientific facts that have not been known at the time of the Quran revelation. Over the past few decades, several of them have been revealed, but many are still waiting to be uncovered. Result : Breastfeeding is the most natural and safest way to provide nutrition, protection and unique bonding experience for newborn babies. The term “milk-kinship” is a kind of relationship via breastfeeding that was established hundreds of years ago via the Qur´an and Sunna. The study revealed that the life expectancy of the F2 offspring obtained from milk-sublings mating was much shorter than the offspring from control group. Which mean that there is period in which offspring are susceptible to breast milk induced epigenetic changes, especially in the first 2 years of life. Conclusion : Recent research suggests that consanguinity via breastfeeding can be explained by heritable mechanism of epigenetic modifications.
The Relationship Of Anti-Inflammation Non Steroid Use Patterns With Side Effects In Patients Post Appendectomy At Jemursari Islamic Hospital Lailia, Shafira Nur; Handayani, Handayani; Bhayusakti, Aditya; Adriansyah, Agus Aan
Jurnal Medis Islam Internasional Vol 5 No 1 (2023): December
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v5i1.4122

Abstract

Background: Appendicitis is a condition where there is acute inflammation of the vermiform appendix which causes patients to undergo surgery frequently. NSAIDs are given to patients after appendectomy surgery to relieve pain. Inappropriate pattern of NSAID use can cause drug side effects. Objective: This study aims to analyze the relationship between the pattern of use of non steroidal anti-inflammatory analgesics and drug side effects in post-appendectomy patients at Jemursari Hospital Surabaya in 2019-2020. Methods: This type of research is descriptive analytic with a cross sectional design. This study used 62 samples medical record of post-appendectomy patients in 2019-2020 who were given NSAID  therapy. Chi-Square Test and Fisher's Exact Test (p<0.05) was used to analyze the relationship between NSAID use patterns and side effects. Results: There was a relationship between the type of drug Mafenamic Acid 500mg with nausea, Ketorolac 30mg with hypotension, Ketorolac 90mg with dizziness, and Santagesic 500mg with dyspepsia (p<0.05). Administration of therapy with less dose was associated with hypotension (p<0.05). The duration of therapy for 4 days was associated with nausea, vomiting and duration of therapy for 5 days was associated with constipation and dyspepsia. Conclusion: The use of drugs (type of drug, accuracy of dose and duration of therapy) of NSAIDs in post-appendectomy patients is associated with drug side effects.
Health Issues of Nigerian Muslim Pilgrims in The Immediate Post-Covid-19 Era Hajj Year 2022– Part II (Non-Communicable Diseases) Saheed, Raji; Isiaka, Ismaila; Mande, Amina Saleh; Ahmad, Adam
Jurnal Medis Islam Internasional Vol 5 No 1 (2023): December
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v5i1.4210

Abstract

Background: Hajj is an important rite in the life of devout Muslims, requiring the devolvement of physical and material resources in its execution. Limitations posed by COVID-19 on the performance of Hajj make the year 2022 hajj to be an atypical one compared to other years' international hajj. Nigerian pilgrims are peculiar as a low-and middle-income country (LAMIC) with the highest number of Muslim pilgrims from Africa. The objective of this article is to review the health implications of Hajj and peculiarities of the post- COVID 19 era, regarding non-communicable diseases in Nigerian pilgrims based on literature, the interaction of authors with pilgrims, and the experiences of an author as a pilgrim. Results: Commonly encountered non-communicable respiratory, cardiovascular, nutritional, gastrointestinal, endocrine, reproductive, neurological, and musculoskeletal health issues in Nigerian pilgrims were explored. Preventive health strategies by individual pilgrims, the national medical team of National Hajj Commission of Nigeria (NAHCON), the Ministry of Health (MOH) of the Kingdom of Saudi Arabia (KSA) and other stakeholders involved directly or indirectly in conducting Hajj rites were appraised. This includes but not limited to illness screening, chronic illness management, life style modification, medication adherence, and accident prevention. Conclusions: It was concluded that the efforts of the Kingdom of Saudi Arabia, as well as Nigeria authorities on Hajj health services, are commendable, though there are still a lot of areas that need to be improved upon.  Significant importance should be given to pre-hajj and post-hajj screening of pilgrims for communicable health issues in pilgrims to enable optimal execution of hajj task and maintenance of pilgrims’ health beyond hajj period.

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