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Jurnal Kedokteran Universitas Palangka Raya
Published by Universitas Palangka Raya
ISSN : 23550015     EISSN : 27235890     DOI : https://dx.doi.org/10.37304
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health
urnal Kedokteran Universitas Palangka Raya dengan scope kesehatan dan kedokteran memuat original article dan review article baik dalam bahasa indonesia dan bahasa inggris. Terbitan 2 kali setahun setiap april dan oktober
Arjuna Subject : Kedokteran - Biokimia, Kedokteran
Articles 117 Documents
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Pengaruh Faktor Sosial Ekonomi dan Lingkungan Terhadap Prevalensi Demam Berdarah Dengue di Wilayah Kerja Puskesmas Sangurara, Bulili dan Birobuli Kota Palu M. Guli, Musjaya; Nita; Yuniati, Eny; Ardiputra, Muh.Akbar; Toemon, Agnes Immanuela
Jurnal Kedokteran Universitas Palangka Raya Vol 12 No 2 (2024): Jurnal Kedokteran Universitas Palangka Raya
Publisher : Fakultas Kedokteran, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/jkupr.v12i2.13102

Abstract

Dengue fever is one of the diseases that is still a problem in Indonesia. The incidence of DHF cases in Central Sulawesi, especially Palu City, has increased every year. Environmental and socio-economic factors affect the breeding of Aedes Aegypti mosquitoes. This study aims to determine the effect of socio[1]economic and environmental conditions on the incidence of DHF in the working areas of Sangurara, Bulili and Birobuli health centers in Palu City, Central Sulawesi. The method used quantitative with cross sectional research design. Sampling using Simple Random Sampling technique. The number of samples was 51 cases and 51 controls. Analysis technique used Chi- Square. From the results of the study, the variables that significantly influenced the incidence of DHF were education (p-value = 0.012), occupation (p-value = 1.000), income (p-value = 0.029), frequency of draining containers (p-value = 0.008), habit of hanging clothes (p-value = 0.031), home environment conditions (p-value = 0.005). While the variables that did not affect the incidence of DHF were the availability of lids on containers (p-value = 1.000), and the presence of larvae in containers (p-value = 0.127). This study concluded that education, income, frequency of container draining, habit of hanging clothes and home environmental conditions had a significant influence on the incidence of DHF and there was no influence between occupation, availability of container lids and the presence of larvae in containers.
Skrining Fitokimia Tumbuhan Potensi Obat Kanker Kolorektal Begonia Medicinalis Ardi & D.C. Thomas Ardiputra, Muh. Akbar; Musjaya M. Guli; Andi Saifah; Santi; Bambang Sardi; Wafiq Nurfadilah; Mohammad Rivaldi Putra Pratama; Afifah Islamia
Jurnal Kedokteran Universitas Palangka Raya Vol 12 No 2 (2024): Jurnal Kedokteran Universitas Palangka Raya
Publisher : Fakultas Kedokteran, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/jkupr.v12i2.13207

Abstract

Cancer is a condition in which cells or tissues undergo abnormal progressive growth. Colorectal cancer is cancer that occurs in the colon to rectum organs of humans. Alternative therapy for colorectal cancer treatment is the use of herbs such as Begonia medicinalis Ardi & D.C. Thomas. This study aimed to screen the bioactive compounds in the Begonia medicinalis Ardi & D.C. Thomas. extract and its potential as a colorectal cancer drug. This research consists of two stages, namely the extraction stage using the maceration method and the screening stage. The results showed that the extract of Begonia medicinalis Ardi & D.C. Thomas. positively contains flavonoids, alkaloids, and saponins. These bioactive compounds have potential activity as preventive and curative agents for colorectal cancer through several mechanisms, including suppressing oxidative stress, inhibiting CDK activity, suppressing intestinal inflammation, and increasing floranormal diversity and probiotic barrier activity in the intestine.
Pengetahuan Kecacingan Menggunakan Media Video Pada Siswa Sekolah Dasar Sahariyani, Menik; Sari, Rita Kartika; Tasyahuri, Syabila Aldiffah
Jurnal Kedokteran Universitas Palangka Raya Vol 12 No 2 (2024): Jurnal Kedokteran Universitas Palangka Raya
Publisher : Fakultas Kedokteran, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/jkupr.v12i2.14163

Abstract

Helminthiasis in children still occurs in Seren Rembang. Educational video can enhance knowledge and attitudes in order to reduce the morbidity of Helminthiasis.  This study aims to determine the impact of providing Helminthiasis educational video on the level of knowledge and attitude of students at SDN Seren Rembang. Research method is Quasi Experimental using a "pre-post test one group only" design. Total sampling involved 37 students of SDN Seren Rembang. Two questionnaires utilized to measure the knowledge and the attitude. Data analysis using the Paired Sample t-test. Result : Educational video is able to increase the average level of students' knowledge and attitude from 4.43 into 7.75, and from 30.43 into 33.37, respectively. Paired samples t-test is significant for both knowledge (p = 0,000), and attitude (p = 0,002). This study conclude that providing Helminthiasis educational video affect the level of knowledge and attitude of students at SDN Seren Rembang.
Isolasi Staphylococcus aureus dari Swab Tangan Penjamah Makanan di Kantin Universitas Mataram Hasbi, Nurmi; Rosyunita; Rahim, Adelia Riezka; Ayunda, Rahmah Dara
Jurnal Kedokteran Universitas Palangka Raya Vol 12 No 2 (2024): Jurnal Kedokteran Universitas Palangka Raya
Publisher : Fakultas Kedokteran, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/jkupr.v12i2.15313

Abstract

One of the main qualities of food is seen from the biological safety aspect, such as being free from Pathogenic microorganisms. Staphylococcus aureus is a pathogenic bacterium that can contaminate food ingredients come from the skin of food handlers. S. aureus produces enterotoxins that have a poisoning in consumers.The preliminary observationstated that there were still many food handlers in the Mataram University canteen who did not pay attention to hand hygiene and personal sanitation. This study aims to determine the bacterial contamination of S. aureus swabbed from the hands of food handlers in the Mataram University cafetaria. The method was used in this research is descriptive observational. The research consisted of two stages, namely isolation and biochemical identification. The isolation stage resulted 10 culturable bacterial isolates. All bacteria were able to ferment mannitol on Mannitol Salt Then, the biochemical test identification resulted that all isolates had a positive catalase test, a positive slide coagulase test, Gram-positive, and staphylococci cell. The TSIA test resulted A/A or (acid)/(acid) which indicated that all isolates were able to use diverse carbon sources from sucrose, lactose, glucose. Moreover, other test as sulfur, indole and motility tests were negative. Therefore, all isolates in this study are classified as S. aureus. This research is also a promotive and preventive effort for the campus in implementing hygiene and sanitation for food handlers in the cafetaria.
Studi Literatur: Efektivitas Deteksi Malaria Menggunakan Pemeriksaan Mikroskopis Apusan Darah Charisma, Acivrida Mega; Ekawasti, Fitrine; Azis, Mutiara Zakhilah; Sari, Adela Permata; Suci, Azlin Eva; Putra R, Rafi; Putri, Sintia Cahyani; Sugiarto, Agus Bambang
Jurnal Kedokteran Universitas Palangka Raya Vol 13 No 1 (2025): Jurnal Kedokteran Universitas Palangka Raya
Publisher : Fakultas Kedokteran, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/jkupr.v13i1.17393

Abstract

Malaria is an infectious disease caused by the parasites Plasmodium malariae, Plasmodium vivax, Plasmodium, falciparum, Plasmodium ovale, and Plasmodium knowlesi. The purpose of the literature review is to determine the effectiveness of malaria detection microscopically using blood smears. This research method uses data from scientific publications sourced from PubMed, ScienceDirect, and Google Scholar. Malaria cases in 2019-2021 have increased worldwide. Deaths from malaria that occurred worldwide in 2019-2020 increased by 12%. Indonesia contributes the second largest number of malaria cases in the Asian region after India, especially in the eastern region including Papua Province, West Papua Province, East Nusa Tenggara Province, and Maluku Province. Mortality rates from malaria still occur in several provinces in Indonesia. The purpose of this study is to determine the effectiveness of malaria detection using microscopic examination of blood smears. This research method is a literature review of the description of research results that have been conducted by others. Searches on the Google Scholar and Science Direct search engines use boolean techniques. This journal review was taken because the detection of malaria using blood smear microscopic tests is one of the most commonly used common methods, and can help improve professional competence in diagnosing and planning appropriate treatment for malaria sufferers, so it is relevant for doctors, analysts, and health researchers. Blood smear microscopy is the main way to detect malaria using thick blood preparations, this test can find Plasmodium malariae, Plasmodium vivax, Plasmodium, falciparum, Plasmodium ovale, Plasmodium knowlesi even in small amounts. Thin blood preparations help identify parasite species accurately.  
Ketidakseimbangan Th17 dan Treg Pada Pasien PCOS Dengan Resistensi Insulin: Tinjauan Literatur Terhadap Potensi Suntikan Terapi Franciska, Shelly; Hestiantro, Andon; Kartika, Tasya
Jurnal Kedokteran Universitas Palangka Raya Vol 13 No 1 (2025): Jurnal Kedokteran Universitas Palangka Raya
Publisher : Fakultas Kedokteran, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/jkupr.v13i1.17456

Abstract

Polycystic ovary syndrome or polycystic ovary syndrome (PCOS) is a metabolic-endocrine disorder characterized by oligoovulation/anovulation, hyperandrogenism, and polycystic ovaries on ultrasound. Globally, PCOS affects 6-21% of women of reproductive age and about 95% of them experience insulin resistance. In Indonesia, the prevalence of PCOS reaches 5-10% where 72.04% are associated with infertility and insulin resistance. Immunoendocrinology notes that the immune response plays a role in the development of PCOS. Several mechanisms cause chronic inflammation caused by insulin resistance, hyperandrogenemia, and dyslipidemia. Research shows a correlation between pro-inflammatory cytokines, especially T-helper 17 (Th17) cells and T-regulatory cells (Treg), in PCOS and insulin resistance. Th17 cells increase inflammation, while Tregs play the opposite role, with their differentiation modulated by interleukin-6 (IL-6) and Transforming Growth Factor-β (TGF-β). Th17/Treg balance can be regulated by targeting IL-6. This study compared Th17 and Treg levels in PCOS patients with and without insulin resistance using IL-17 and IL-10 markers. Th17 was higher and Treg was lower in PCOS with insulin resistance, resulting in a higher Th17/Treg ratio compared to patients without insulin resistance. The results of this study provide an opportunity to target the Th17/Treg axis in new therapies to break the cycle of PCOS and insulin resistance and reduce complications
Literature Review: Comparative Analysis of Sputum Cytology Examination Methods & Fine Needle Aspiration (Fnab) For Lung Cancer Khairunnisa; Guli, Musjaya M.
Jurnal Kedokteran Universitas Palangka Raya Vol 13 No 1 (2025): Jurnal Kedokteran Universitas Palangka Raya
Publisher : Fakultas Kedokteran, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/jkupr.v13i1.18678

Abstract

Cancer remains one of the biggest medical challenges, with high mortality rates due to late detection and limited treatment. In 2020, Indonesia saw 396,914 new cancer cases and 234,511 cancer deaths. The purpose of this paper is to provide a strong foundation for the research being conducted, by utilizing knowledge and findings from previous studies related to the FNAB method and sputum cytology in patients with lung cancer. The sources used in this writing are Google, NIH, NCBI, and other national journals. The selection of methods must be adjusted to the patient's condition, risk factors, and the availability of medical facilities, with the main objective of achieving a rapid, accurate, and precise diagnosis, so as to determine the most appropriate therapy for lung cancer patients. This study shows that FNAB and sputum cytology have their respective advantages in the diagnosis of lung cancer. FNAB is highly effective for diagnosing small lung nodules, especially in high-risk patients, due to its high accuracy and ability to provide more detailed diagnostic information. In contrast, sputum cytology is more suitable for early detection and screening in high-risk populations, although its accuracy is lower and limited to certain types of cancer
Hubungan Aktivitas Pengunaan Gadget Terhadap Kejadian Miopia Pada Mahasiswa Fakultas Kedokteran Universitas Palangka Raya Hertanto, Bima Adithya; Martani, Natalia Sri; Adnyana, I Gde Hary Eka; Manalu, Rosmaryati; Augustina , Indria
Jurnal Kedokteran Universitas Palangka Raya Vol 13 No 1 (2025): Jurnal Kedokteran Universitas Palangka Raya
Publisher : Fakultas Kedokteran, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/jkupr.v13i1.19254

Abstract

Technological advancements, particularly gadget use, offer benefits but increase myopia risk. Myopia prevalence is rising globally, including in Indonesia, especially among adolescents and young adults. Factors like viewing distance, usage duration, room light intensity, screen brightness, and posture contribute to this trend. This study aims to determine the relationship between gadget usage and myopia among students of the Faculty of Medicine, Universitas Palangka Raya, Class of 2023. A cross-sectional study was conducted with 85 respondents. Data were collected via questionnaires and eye examinations, analyzed using Spearman’s correlation test. Significant relationships were found between usage duration, room light intensity, screen brightness, and viewing distance with myopia. Posture during gadget use showed no significant relationship. Gadget usage activities are significantly associated with myopia incidence among respondents.
Perbandingan Kadar Profil Lipid Pasien Stroke Iskemik dan Hemoragik di RSUD Sultan Imanuddin Kotawaringin Barat Aisyah, Nurul; Aprianie, Wiwin; Hidayati, Laratika; Puspa Dewi, Ni Putu Sinta
Jurnal Kedokteran Universitas Palangka Raya Vol 13 No 1 (2025): Jurnal Kedokteran Universitas Palangka Raya
Publisher : Fakultas Kedokteran, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/jkupr.v13i1.19554

Abstract

Stroke penyakit ketiga tak menular penyebab kematian di dunia, dengan prevalensi di Indonesia mencapai 10,9% kasus per tahun. Salah satu penyebab stroke yaitu dislipidemia mengenai kondisi kadar lipid abnormal dalam aliran darah yang menimbulkan faktor risiko signifikan terhadap penyakit kardiovaskular. Tujuan penelitian ini yaitu membandingkan kolesterol total, trigliserida, LDL, dan HDL pasien stroke hemoragik dan stroke iskemik di RSUD Sultan Imanuddin, Pangkalan Bun dengan desain penelitian analitik kuantitatif serta pendekatan cross-sectional. Data diambil dengan metode purposive sampling dari data sekunder berupa catatan rekam medis pasien stroke hemoragik dan iskemik di RSUD Sultan Imanuddin, Kotawaringin Barat, Pangkalan Bun periode Januari - Desember 2023. Pengujian homogenitas dilakukan dengan uji Lavene, dan pengujian normalitas data dilakukan dengan metode Kolmogrov Smirnov. Analisis data dilakukan dengan menggunakan non-parametrik yaitu uji Mann-Whitney. Hasil penelitian menunjukkan rata-rata kadar kolesterol total, trigliserida, LDL, dan HDL yaitu 198±48; 130±69; 129±45; dan 41±15 mg/dl pada stroke iskemik, dan 189±60; 105±55; 119±54; dan 47±13 mg/dl pada stroke hemoragik. Hasil uji Mann-Whitney menunjukkan adanya perbedaan bermakna kadar profil lipid antara pasien stroke iskemik dengan stroke hemoragik. Hasil uji regresi logistik biner menunjukkan bahwa pada kadar LDL dan HDL terdapat perbedaan yang bermakna terhadap pasien stroke iskemik dan hemoragik, sedangkan tidak ada perbedaan yang bermakna antara kadar kolesterol total dan trigliserida pada pasien stroke iskemik dan hemoragik. Kesimpulan kadar profil lipid memiliki peran penting dalam membedakan jenis stroke hemoragik dan iskemik, serta dapat menjadi indikator dalam evaluasi risiko penyakit stroke
Faktor-Faktor yang Mempengaruhi Peyakit Diabetes Melitus di Kota Palu Musjaya M.; Ayu Dia Agustina; Nur Annisa Safirah; Ardiputra, Muh. Akbar; Sardi, Bambang; Saifah, Andi; Putra, Suwarty Nursahara Usman
Jurnal Kedokteran Universitas Palangka Raya Vol 13 No 1 (2025): Jurnal Kedokteran Universitas Palangka Raya
Publisher : Fakultas Kedokteran, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/jkupr.v13i1.19586

Abstract

Diabetes mellitus is a metabolic disorder caused by insufficient production of the hormone insulin by the pancreas. This disease can be said to be a chronic disease because it can occur over a long period . This research is about the factors that influence Diabetes Melitus disease in Palu City. This study aims to determine the description of patient visits suffering from Diabetes Melitus at the Central Sulawesi Provincial Laboratory. The sampling technique uses the purpose sampling method, namely purposeful sampling or sampling carried out with subjects based on criteria set by the researcher. The results of this study analyze the factors that influence Diabetes Melitus disease in Palu City. The research result obtained were that there were more women with 288 people and 132 men. Meanwhile, in 2024 from January to march, there will be 90 women and 44 men, the number of patients suffering from diabetes melitus. Namely those aged 46-55 ini 2023 there will be 240 people and ini 2024 there will be 143 people with diabetes melitus agen 40-59 person. The gender factor is that there are more female sufferers of diabetes mellitus compared to male sufferers    

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