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Jurnal Kedokteran Universitas Palangka Raya
Published by Universitas Palangka Raya
ISSN : 23550015     EISSN : 27235890     DOI : https://dx.doi.org/10.37304
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health
urnal Kedokteran Universitas Palangka Raya dengan scope kesehatan dan kedokteran memuat original article dan review article baik dalam bahasa indonesia dan bahasa inggris. Terbitan 2 kali setahun setiap april dan oktober
Arjuna Subject : Kedokteran - Biokimia, Kedokteran
Articles 117 Documents
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Pola Perlukaan Kecelakaan Lalu Lintas Lansia Berdasarkan Data HDSS Sleman Pada Tahun 2020-2022 Wiraagni, Idha Arfianti; Supriyadi, Shea Sapphira; Artanti, Martiana Suciningtyas Tri; Priyambodo, Dewanto Yusuf
Jurnal Kedokteran Universitas Palangka Raya Vol 13 No 1 (2025): Jurnal Kedokteran Universitas Palangka Raya
Publisher : Fakultas Kedokteran, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/jkupr.v13i1.19648

Abstract

Traffic accidents are incidents that have a high incidence and can cause great losses to society. In cases of traffic accidents, it is recorded that many non-productive ages experience serious injuries. This study aims to analyze the pattern of traffic accident injuries in the elderly in Sleman based on Sleman HDSS data for 2020-2022. This study is an analytical observational study with a cross-sectional approach. The population of this study was the people of Sleman Regency aged 60 years and over. The sampling technique used is simple random sampling. Based on the analysis of 272 respondents with 401 cases of injury, it was found that the most injuries occurred in the lower limbs and the degree of injury was mild with the most types of combined injuries. For moderate and severe degrees of injury, they have the same prevalence. Burns are the type of injury with the least, namely only 1 case. The largest number of respondents were elderly people aged 60-70 years, namely 72% of the total respondents. The conclusion of this study is that minor injuries are the most common type of injury, with lower limbs being the most common location of injury and combination injuries being the most common type of injury. In the bivariate results, there was no relationship between age and type, location, and severity. This shows that type, location, and severity can occur at any age and do not differ in each age group.
The Relationship Between Predisposing Factors and The Incidence of Chronic Suppurative Otitis Media Nayoan, Christin Rony; Maharani , Arum; Towidjojo, Vera Diana; Syamsi, Nur
Jurnal Kedokteran Universitas Palangka Raya Vol 13 No 2 (2025): Jurnal Kedokteran Universitas Palangka Raya
Publisher : Fakultas Kedokteran, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/jkupr.v13i2.20362

Abstract

One of the health problems in Indonesia is hearing loss which can be caused by otitis media. The incidence of Chronic Suppurativa Otitis Media (CSOM) in the world ranges from 65-330,000,000 per year. Research shows that in 2020, in the ENT Clinic at Anutapura General Hospital, recorded 289 out of 506 patients seeking treatment for ear problems, making it the most cases compared to nose and throat problems. Predisposing factors for CSOM include nutritional status, immunity, history of Acute Otitis Media (AOM), history of Acute Respiratory tract Infection (ARI), exposure to cigarette smoke and nutritional status.The objective of this study is to determine the relationship between predisposing factors and the incidence of CSOM in the ENT clinic at Undata General Hospital, Central Sulawesi. This study was a cross-sectional analytic observational study conducted at the ENT clinic of Undata General Hospital, Central Sulawesi. Sampling was done using purposive sampling technique by setting certain criteria. Participants were asked to fill out a questionnaire that could help researchers identify possible risk factors for CSOM to collect primary research data. Data analysis in this study used bivariate data analysis to test the relationship between two variables. Based on the results of bivariate analysis using the chi-square test, the p-value of the factors studied was 0.299 for immune status, 0.35 for genetic factors, 0.04 for history of ARI, 0.000 for history of AOM, 1.000 for cigarette smoke exposure, 0.792 for nutritional status, 0.045 for age and 0.193 for gender. Conclusion of this study, predisposing factors that are significantly associated with the incidence of CSOM in the ENT clinic of Undata general hospital are history of ARI, history of AOM and age.  
The Relationship Between Sleep Duration And Obesity Among Medical Students at The Faculty of Medicine, University of Muslim Indonesia, Class of 2021 Darmawan, Inchi Muh Arrayyan; Rijal, Syamsu; Muchtar, Amrizal; Nurmadilla, Nesyana; Ismail, Muhammad Wirasto 
Jurnal Kedokteran Universitas Palangka Raya Vol 13 No 2 (2025): Jurnal Kedokteran Universitas Palangka Raya
Publisher : Fakultas Kedokteran, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/jkupr.v5i1.20388

Abstract

Obesity is a growing health problem worldwide, including in Indonesia. One factor associated with obesity is inadequate sleep duration. This study aims to determine the relationship between sleep duration and obesity among medical students at the Faculty of Medicine, University of Muslim Indonesia, class of 2021. An analytical cross-sectional design was used. The study sample consisted of 45 students with inclusion criteria of having a BMI > 25 kg/m² and experiencing sleep duration disorders. Data were collected using a questionnaire and analyzed using the Chi-Square test and Cramer's V test. The results showed that the majority of students had adequate sleep duration (53.3%) and were more frequently classified in the Obesity II category (77.8%). The Chi-Square test revealed a significant association between sleep duration and obesity category. The Cramer's V test indicated a moderate correlation between sleep duration and obesity. There is a significant relationship between sleep duration and obesity in students of the Faculty of Medicine, Muslim University of Indonesia, class of 2021
Changes In Astigmatism Before and After Pterygium Surgery at The Jec Orbita Makassar Eye Clinic From 2021 to 2023 Hafsah, Waode; Suliati P. Amir; Hanna Aulia Namirah; Sri Irmandha Kusumawardani; Nur Aulia
Jurnal Kedokteran Universitas Palangka Raya Vol 13 No 2 (2025): Jurnal Kedokteran Universitas Palangka Raya
Publisher : Fakultas Kedokteran, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/jkupr.v13i2.21013

Abstract

Pterygium is an abnormal growth of the conjunctiva onto the cornea that often causes astigmatism and impairs vision. Exposure to ultraviolet (UV) rays is a major risk factor. This study aims to analyze changes in astigmatism in pterygium patients who underwent surgery at the JEC Orbita Eye Clinic in Makassar between 2021 and 2023. An analytical observational study with a cohort approach was used to measure changes in astigmatism before and after surgery. The study sample consisted of 26 patients with pterygium who had complete medical records. Data were collected from medical records and analyzed using the Wilcoxon test. The results showed that the majority of patients (53.8%) had mild astigmatism before surgery. After surgery, most patients (53.8%) still had mild astigmatism, with some patients experiencing a significant decrease. The Wilcoxon test showed a significant difference between astigmatism before and after surgery, indicating a significant improvement in most patients. The conclusion of this study shows that pterygium surgery has a significant effect on reducing astigmatism in patients. Although the majority of patients experienced visual improvement after surgery, some patients still showed high astigmatism. The size of the pterygium and the surgical technique play an important role in postoperative results
Macroscopic Features of The External Auditory Canal in Patients with Otitis Externa With Otoscopic Examination at The Ent Polyclinic of Tamiang Layang Hospital Anugerahny, Margaretha Yayu Indah; Mutiasari, Dian
Jurnal Kedokteran Universitas Palangka Raya Vol 13 No 2 (2025): Jurnal Kedokteran Universitas Palangka Raya
Publisher : Fakultas Kedokteran, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/jkupr.v13i2.21517

Abstract

Otitis externa is one of the most painful types of inflammation is one of the common external auditory canal diseases in clinical practice. Otitis externa is an inflammation of the external auditory canal caused by bacteria, fungi. The aim of this study was to determine the characteristics of otitis externa treated at the ENT polyclinic of Tamiang Layang Hospital in 2022-2023. This study is a descriptive study using a retrospective approach using secondary data, namely medical records of patients diagnosed with otitis externa at the ENT-KL Polyclinic of Tamiang Layang Hospital in 2022-2023. This study had a sample of 335 otitis externa patients. Otitis externa occurs more in women, namely 196 patients (58.5%). The largest age group was 26-45 years, 132 patients (39.4%). The most common diagnosis was diffuse otitis externa, 291 patients (86.9%). Most macroscopic features were hyperemic
Immunotherapy and Immune Checkpoints: Unlocking The Immune System’s Potential to Treat Cancer Rizqoh, Debie; Febrina, Olivia Putri; Pratiwi, Ulfa Hanum; Ramadhani, Abdah Zhafirah; Athalia , Nabila Wine
Jurnal Kedokteran Universitas Palangka Raya Vol 13 No 2 (2025): Jurnal Kedokteran Universitas Palangka Raya
Publisher : Fakultas Kedokteran, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/jkupr.v13i2.21738

Abstract

Conventional cancer therapies, such as surgery, chemotherapy, and radiation therapy, often produce limited results and negatively affect patients' quality of life. In recent years, immunotherapy based on immune checkpoint inhibitors (ICIs) has emerged as a promising new approach. Immune checkpoint molecules, such as PD-1, PD-L1, and CTLA-4, play a crucial role in suppressing the immune response to tumors, making them primary targets in ICI therapy. This study examines the mechanisms of immune checkpoints, the efficacy of ICI therapy, and the remaining challenges in clinical practice. The review was conducted through a literature review of scientific publications and the latest clinical trial results. The results demonstrate the efficacy of ICIs, such as ipilimumab and pembrolizumab, in improving overall and progression-free survival rates across various types of cancer, particularly melanoma and non-small cell lung cancer. Combining two ICIs has been shown to have higher synergistic effects than monotherapy, as demonstrated in the CheckMate 067 and KEYNOTE-024 clinical trials. Despite its promise, this therapy is not fully effective in all patients due to immune resistance, autoimmune side effects, and the complexity of tumor heterogeneity and the immune microenvironment. Therefore, combination therapy strategies, dose adjustments, schedule modifications, and personalized approaches based on biomarkers are needed to optimize clinical benefits and expand the scope of therapy. In conclusion, ICIs hold great potential for future cancer therapies and are being developed to be more effective and personalized.  
Analysis of Microscopy and RDT Performance in Detecting Malaria Among Suspected Patients at Arso III Health Center Hartati, Risda; Ap, Ema Elvira Alwina; Asrianto; Sahli, Indra Taufik; Kurniawan, Fajar Bakti; Wardani, Afika Herma; Purwati, Rina
Jurnal Kedokteran Universitas Palangka Raya Vol 13 No 2 (2025): Jurnal Kedokteran Universitas Palangka Raya
Publisher : Fakultas Kedokteran, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/jkupr.v13i2.23060

Abstract

Malaria remains a significant public health problem in Papua. Keerom is one of the districts with a high incidence of malaria. This study aims to evaluate the performance of the Rapid Diagnostic Test (RDT) in comparison to microscopic examination, the gold standard for malaria diagnosis. This descriptive analytic study involved 40 suspected malaria patients at Arso III Health Center, Skanto District, Keerom Regency, Papua. Blood samples were examined using thick blood smears, thin blood smears, and the Care Start RDT. The study employed a cross-sectional design with purposive sampling. Microscopic examination identified five positive cases, corresponding to 12.5 percent, while the RDT detected nine positive cases, representing 22.5 percent of the total. The diagnostic analysis of the RDT revealed a sensitivity of 100 percent, a specificity of 88.6 percent, a positive predictive value of 55.6 percent, and a negative predictive value of 100 percent. The McNemar test showed a significant difference, p = 0.046. RDT proved reliable for excluding malaria, as no false-negative results were found. However, positive results require confirmation by microscopy or PCR to avoid misidentification and treatment errors.

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