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Jurnal Insan Farmasi Indonesia
Published by Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin
ISSN : 26213184     EISSN : 26214032     DOI : https://doi.org/10.36387/jifi
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Physics
Focus and Scope Jurnal Insan Farmasi Indonesia (JIFI) is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIFI is a forum for the publication of quality and original works that open discussions in the field of pharmacy and health sciences.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 20 Documents
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Search results for , issue "2023: JIFI: Webinar " : 20 Documents clear
PENGARUH ERITROPOETIN TERHADAP TINGKAT KEBERHASILAN TERAPI ANEMIA PADA PASIEN ANEMIA PADA PASIEN CHRONIC KIDNEY DISEASE DI RSUD ULIN BANJARMASIN Wahyunita, Sari; Kurniawan, Guntur; Maharani, Sonia
Jurnal Insan Farmasi Indonesia 2023: JIFI: Webinar & call for paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i3.1690

Abstract

Chronic kidney disease (CKD) is kidney damage for more than 3 months. The medical  in hospital  taken was hemodialysis. The aim of this study was to determine the success rate of anemia therapy, the incidence of anemia in CKD patients, and determine the effect of erythropoietin administration on the success rate of anemia therapy in CKD patients at Ulin Hospital, Banjarmasin. This research is a non-experimental research, observational in nature. Data collection was carried out prospectively. The sample used in this study was patient hemoglobin data in medical records that met the inclusion and exclusion criteria. The sample selection method used was total sampling. The measurement of therapeutic success used is the patient's hemoglobin data after being given erythropoietin. The research data obtained is displayed descriptively analytically. The research results of 90 patients with CKD (Chronic Kidney Disease). The results obtained were that 50 patients (55.55%) achieved success in anemia therapy and 40 patients (45.45%) did not achieve success in anemia therapy. The incidence of anemia was 90 patients (100%). Based on the analysis of data obtained, there is an influence of erythropoietin on the success of anemia therapy in Chronic Kidney Disease (CKD) at Ulin Regional Hospital, Banjarmasin.
ANALISIS EFEKTIVITAS BIAYA PENGOBATAN HIPERTENSI PADA PASIEN RAWAT JALAN DI KLINIK NURUL HASANAH TAHUN 2022 Akbar, Depy Oktapian; Yaumil, Fairuz; Apdillah Setiawan, Aldi
Jurnal Insan Farmasi Indonesia 2023: JIFI: Webinar & call for paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i3.1691

Abstract

Hypertension or high blood pressure is a serious medical condition that significantly increases the risk of heart, brain, kidney and other diseases. Prevalence of the population with high blood pressure is 34.11%. The aim of this research is to determine the cost effectiveness between the use of the antihypertensive drugs amlodipine and candesartan in BPJS outpatient hypertension patients at the Nurul Hasanah Kapuas Clinic in 2022. This research uses the CEA pharmacoeconomic method based on the direct medical cost perspective used, namely health service cost data. The results obtained from this research are that amlodipine therapy is more cost effective than candesartan with an Average Cost Effectiveness Ratio (ACER) value for amlodipine of Rp. 156,441.92 and candesartan Rp. 166,527.78.
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL 96% DAUN RAMANIA (Bouea macrophylla Griffith.) DARI DAERAH KALIMANTAN SELATAN DENGAN METODE DPPH Saftia Aryzki; Setia Budi; Yanti
Jurnal Insan Farmasi Indonesia 2023: JIFI: Webinar & call for paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i3.1692

Abstract

Ramania (Bouea macrophylla Griffith.) is a herbal plant that has antioxidant properties and inhibits free radicals. This research aims to determine the antioxidant potential of ramania leaf ethanol extract by looking at the IC50 value. Ramania leaves were extracted using the maceration method using 70% ethanol solvent. Antioxidant potential is determined using the DPPH (1,1-diphenyl-2-picrylhydrazyl) method by comparing vitamin C which has been proven to have very potent free radical potential. The ramania leaves made had a concentration of 10% and then diluted to a concentration of (20,40,60,80,100) µg/mL. 2 mL of each infusion was taken and reacted with 2 mL of 50 µg/mL DPPH solution in an aluminum-lined test tube for a period of time (30 minutes). The results showed that the IC50 value of the ethanol extract of ramania leaves was 0.8126 ± 78.56387 µg/mL. The IC50 value obtained was compared with the inhibition value of the vitamin C solution made with varying concentrations (2,4,6,8,10) µg/ mL, based on this value, ramania leaf extract from the Sleman area is categorized as very potent so it can be developed as a source of antioxidants from natural ingredients.
HUBUNGAN RIWAYAT KERJA TERHADAP PENGETAHUAN VALIDASI DAN KUALIFIKASI BERDASARKAN CPOTB DI USAHA KECIL OBAT TRADISIONAL PT. X di DAERAH ISTIMEWA YOGYAKARTA Banafsaj, Zakia Irbah; Dwinta, Eliza; Emelda, Emelda; Sarwadhamana, Raden Jaka
Jurnal Insan Farmasi Indonesia 2023: JIFI: Webinar & call for paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i3.1694

Abstract

Validation and qualification are important activities the pharmaceutical industry to produce quality and safe drugs. Good Manufacturing Practices for Traditional Medicines (CPOTB) is a guideline for the traditional medicine industry to produce medicines with guaranteed quality from validation and qualifications. Employee knowledge in carrying out validation and qualifications in the traditional medicine industry is very necessary to support the production quality assurance process. The aim of the research is to determine the relationship between work history (length of work and work area) on validation knowledge and qualifications based on CPOTB in the small business of traditional medicine PT. X in the Special Region of Yogyakarta. The type of research is descriptive quantitative with a cross sectional method. The research uses primary data from questionnaires of 35 employees who work in the production sector of PT. X. The results showed that there was no work history relationship with employee knowledge of CPOTB, with a p-value of 0.496 (<0.05) in the length of work and a p-value of 0.724 (<0.05) in the work area. From the data it can be concluded that the length of work and employee work area in the production sector are not related to employee knowledge of CPOTB.
EFEKTIVITAS ANTIBAKTERI EKSTRAK DAUN KECAPI (Sandoricum koetjape Merr) TERHADAP PERTUMBUHAN BAKTERI Enterococcus faecalis Yusrinie Wasiaturrahmah; Muhammad Rayhan; Deby Kania Tri Putri; Agung Satria Wardhana; Maharani Laillyza Apriasari
Jurnal Insan Farmasi Indonesia 2023: JIFI: Webinar & call for paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i3.1699

Abstract

Penyebab terbesar kegagalan perawatan saluran akar sebesar 63% disebabkan oleh bakteri Enterococcus faecalis. Bakteri Enterococcus faecalis dapat dieliminasi dengan melakukan irigasi saluran akar. Kandungan zat aktif seperti saponin yang terdapat di dalam daun kecapi (Sandoricum koetjape Merr) terbukti memiliki efek antibakteri. Tujuan mengukur dan menganalisis efektivitas antibakteri ekstrak daun kecapi (Sandoricum koetjape Merr) terhadap pertumbuhan bakteri Enterococcus faecalis. Metode penelitian ini merupakan eksperimen murni (true experimental) dengan post test only with control group design. Penelitian ini terdiri dari 9 kelompok perlakuan, yaitu ekstrak daun kecapi (Sandoricum koetjape Merr) konsentrasi 10%, 20%, 30%, 40%, 50%, 60%, 70%, sodium hipoklorit (NaOCl), dan aquadest dengan 3 kali pengulangan. Data KHM didapatkan dari pengukuran delta Optical Density (OD) dan data uji KBM didapatkan berdasarkan perhitungan jumlah koloni. Berdasarkan nilai rata-rata dan analisis data diketahui KHM terdapat pada konsentrasi ekstrak daun kecapi 10% dan KBM pada konsentrasi 20%. Ekstrak daun kecapi (Sandoricum koetjape Merr) konsentrasi 10%, 20%, 30%, 40%, 50%, 60%, dan 70% memiliki efektivitas antibakteri terhadap pertumbuhan bakteri Enterococcus faecalis.
PERBEDAAN AKTIVITAS ANTIOKSIDAN PADA KOLANG KALING SEGAR DAN KOLANG KALING SERBUK Eka Susanti Hanhadyanaputri; Ariani Hesti Wulan; Indah Sulistyarin; Intan Martha Cahyani
Jurnal Insan Farmasi Indonesia 2023: JIFI: Webinar & call for paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i3.1704

Abstract

Kolang kaling (Arenga pinnata) is one of the results of the palm tree. The process of processing palm fruit into and fro can affect the quality of the fruit and fro produced.  The purpose of this study was to determine the physico-chemical characteristic, IC 50 value of fresh fruit and fro, the powder was dried in the microwave at low temperature (40oC) for 5 days, medium (53oC) for 4 hours and high (78oC) for 2 hours, and to find out whether there are effect of difference in fresh fruit and fro treatment on antioxidant activity.  Fresh fruit and fro were tested for phytochemical screening and FTIR, physicochemical characteristics and antioxidant, Antioxidant testing used the DPPH (1,1-diphenyl-2-picrylhidrazyl) method. The results of phytochemical screening and FTIR showed the presence of galactomanan compounds.  The antioxidant test results obtained the IC50 value of fresh fruit and fro, the powder was dried in the microwave at low temperature, medium and high respectively 104.8488; 25.2963; 90.0155 and163.4381 ppm. The statistical test results showed a value of 0.000<0.05,  there is a difference IC50 between groups
INKORPORASI MIKROEMULSI EKSTRAK ETANOL AKAR KELAKAI (Stenochlaena Palustris (Burn. F) Bedd.) PADA FORMULASI TONER WAJAH DENGAN VARIASI KONSENTRASI GLISERIN Forestryana, Dyera; Muawiyyah, Walidatun; Indah Sayakti, Putri
Jurnal Insan Farmasi Indonesia 2023: JIFI: Webinar & call for paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i3.1706

Abstract

The face is one part of the human body that needs to be kept healthy and clean. Efforts can be made to maintain facial cleanliness by using facial toner. The extract of kelakai root has activity as an antioxidant. Incorporation of kelakai root extract microemulsion in the toner formulation will increase the cleaning ability and optimal absorption of active substances. This research aims to obtain an optimum face toner formula. The kelakai roots were macerated with 70% ethanol solvent. The kelakai microemulsion consisted of Tween 80 35% w/v and PEG 400 15% w/v. Incorporation of 2% w/v microemulsion into the toner formula with varying glycerin concentrations of 2%, 3%, 4%, and 5% w/v. Evaluation through stability tests with organoleptic, homogeneity, pH, viscosity, clarity, and density. Organoleptic, homogeneity, and clarity before and after the stability test provide a liquid form, odorless, clear, and homogeneous color. In the pH test, the pH value of the preparation was stable in the pH range of 4.5-6.5. The viscosity of toner preparations is in a range of 1-24.5 cPs. The density stability with a range of 1.003-1.015 gr/mL. The optimum formula, namely F2 with 3% glycerin, provides good toner stability based on physical quality tests.
FORMULASI OBAT KUMUR EKSTRAK DAUN BINAHONG DAN KAYU MANIS TERHADAP BAKTERI Streptococcus mutans Rakhmayanti, Regia Desty; Nur Aisiyah, Astri Dewi
Jurnal Insan Farmasi Indonesia 2023: JIFI: Webinar & call for paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i3.1781

Abstract

Dental caries is a disease in the oral cavity, this disease can be prevented by using mouthwash. Plants that have antibacterial activities include binahong leaves  and cinnamon . This study aims was to determine the quality and antibacterial activity of mouthwash that containing against Streptococcus mutans. Mouthwash preparations was carried out by various concentrations of binahong leaves and cinnamon extract. Preparation F0 is without extract, F1 (6%:3%), F2 (7%:3%), F3 (8%:3%). The organoleptic test results of the mouthwash was clear brown in color and had a distinctive aroma of binahong leaves and cinnamon. The pH test results were F0 6.529±0.16; F1 5.256±0.004; F2 5.333±0.002; and F3 5.373±0.003. The density measurements results were F0 1.0766±0.04852; F1 1.0309±0.00056; F2 1.0317±0.00032; and F3 1.0364±0.00325. The viscosity measurement results were F0 3.170±0.02; F1 3.203±0.02; F2 3.323±0.01; and F3 3.380±0.02. The antibacterial activity test result were F0 0.00 mm; F1 6.39±0.03 mm; F2 7.29±0.06 mm; F3 8.89±0.07 mm; negative control (distilled water) 0.00 mm; and positive control (chlorhexidine 0.2%) 21.35±0.10 mm. The preparation fulfilled the physical quality parameter requirements of mouthwash and has antibacterial activity against Streptococcus mutans.
EVALUASI PENGELOLAAN PENYIMPANAN SEDIAAN FARMASI DI GUDANG INSTALASI FARMASI RSIA IBUNDA PELAIHARI Ilahi, fitrah shafran; Tia Nor Aprilia; Abdul Mahmud Yumassik; Amaliyah Wahyuni
Jurnal Insan Farmasi Indonesia 2023: JIFI: Webinar & call for paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i3.1819

Abstract

Drug storage in hospital pharmacy installations is a guarantee of the feasibility of drugs received by the hospital before being distributed to patients.  pharmaceutical preparations used by the pharmaceutical installation warehouse at RSIA Ibunda Pelaihari based on the quality standards of the Minister of Health regulation number 72 of 2016 concerning service standards in hospitals. The research method uses a qualitative observational method, the research instrument used in data collection is an observational sheet. The results showed that the storage of pharmaceutical preparations in the pharmaceutical installation warehouse of RSIA Ibunda Pelaihari obtained a figure of 92% which was included in the good criteria based on the results of the calculation of the observation sheet carried out in the pharmaceutical installation warehouse of RSIA Ibunda Pelaihari by showing parts that were in accordance with the Permenkes standard number 72 of 2016, namely storage components, storage system, storage method. While as many as 8% that have not met the standards are the storage requirements and storage equipment. The storage of pharmaceutical preparations in the pharmaceutical warehouse of RSIA Ibunda Pelaihari has met the standards of Permenkes number 72 of 2016 with a percentage of 92% which is in the good category.
EVALUASI PENGGUNAAN ANTIBIOTIK PASIEN PNEUMONIA DENGAN METODE GYSSENS Gemy Nastity Handayany; Dwi Yuliana
Jurnal Insan Farmasi Indonesia 2023: JIFI: Webinar & call for paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i3.1866

Abstract

The purpose of this study is to determine the rationality of using antibiotics in pneumonia patients with the gyssens method in the inpatient installation of Nene Mallomo Hospital, Sidrap Regency for the 2021 period. This type of research is descriptive research with a quantitative approach conducted retrospectively. The results of the evaluation of the use of antibiotics based on the gyssens method were obtained the use of appropriate / rational antibiotics (category 0) by 14% and irrational use of antibiotics by 86% which were divided into other antibiotics that were more effective (category IVa) by 67%, the use of antibiotics too long (category IIIa) by 5%, the use of antibiotics too short (category IIIb) by 13% and the use of antibiotics not right dose (category IIa) by 1%. In this study, it can be concluded from the category assessed that the use of antibiotics in pneumonia patients at Nene Mallomo Hospital, Sidrap Regency is irrational.

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