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All Journal Jurnal Gizi dan Dietetik Indonesia (Indonesian Journal of Nutrition and Dietetics) Jurnal Nasional Komputasi dan Teknologi Informasi Pharmaceutical Journal of Indonesia Aksara: Jurnal Ilmu Pendidikan Nonformal Lumbung Farmasi : Jurnal Ilmu Kefarmasian Hubungan Tingkat Pengetahuan Petugas Pengelola Obat dengan Tingkat Ketersediaan Obat Di Puskesmas Kota Malang Jurnal Insan Farmasi Indonesia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Journal of Scientific Research, Education, and Technology
emelda, emelda
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Efek Antidiare Ekstrak Etanol Daun Kelor (Moringa oleifera L.) Pada Mencit Putih Jantan Fauzi, Rizal; Fatmawati, Annisa; Emelda, Emelda
Pharmaceutical Journal of Indonesia Vol 6, No 1 (2020)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Diare merupakan peningkatan frekuensi dan penurunan konsistensi feses bila dibandingkan dengan kondisi usus individu normal. Tingginya angka kejadian diare akut dan kronis mendorong para peneliti untuk terus berusaha dalam menemukan obat  sebagai antidiare baru, terutama yang berasal dari tanaman. Daun kelor (Moringa oleifera Lam) mengandung tanin yang merupakan senyawa polifenol dan berperan dalam proses antidiare. Penelitian ini bertujuan untuk mengetahui aktivitas ekstrak etanol daun kelor sebagai antidiare dengan melihat motilitas usus. Proses ekstraksi dilakukan dengan metode maserasi dengan menggunakan pelarut etanol 70%. Uji aktivitas antidiare dilakukan dengan metode transit intestinal dengan melihat perbandingan usus yang dilalui marker dengan panjang usus secara keseluruhan. Dari penelitian ini diketahui bahwa  nilai rata-rata rasio kelompok perlakuan lebih kecil dibandingkan dengan kelompok kontrol negatif (0,708).  Nilai rata-rata rasio  kelompok yang hewan mencit yang diberikan ekstrak etanol daun kelor (EEDK) dengan dosis 9,1 mg/20 g berat badan mencit adalah 0,664; kelompok dengan dosis EEDK 18,2 mg/20 g  berat badan mencit  sebesar 0,434 dan kelompok dengan dosis EEDK 36,4 mg/20 g  berat badan mencit  sebesar 0,389.  Dari nilai tersebut diketahui  ekstrak etanol daun kelor mempunyai efek antidiare melalui penghambatan motilitas usus. Efek ekstrak etanol daun kelor dalam menghambat motilitas usus paling baik pada pemberian dengan dosis 36,4 mg/20 g BB dengan nilai rata-rata rasio sebesar 0,389
Efek Antidiare Ekstrak Etanol Daun Kelor (Moringa oleifera L.) Pada Mencit Putih Jantan Fauzi, Rizal; Fatmawati, Annisa; Emelda, Emelda
Pharmaceutical Journal of Indonesia Vol 6, No 1 (2020)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.pji.2020.006.01.6

Abstract

Diare merupakan peningkatan frekuensi dan penurunan konsistensi feses bila dibandingkan dengan kondisi usus individu normal. Tingginya angka kejadian diare akut dan kronis mendorong para peneliti untuk terus berusaha dalam menemukan obat  sebagai antidiare baru, terutama yang berasal dari tanaman. Daun kelor (Moringa oleifera Lam) mengandung tanin yang merupakan senyawa polifenol dan berperan dalam proses antidiare. Penelitian ini bertujuan untuk mengetahui aktivitas ekstrak etanol daun kelor sebagai antidiare dengan melihat motilitas usus. Proses ekstraksi dilakukan dengan metode maserasi dengan menggunakan pelarut etanol 70%. Uji aktivitas antidiare dilakukan dengan metode transit intestinal dengan melihat perbandingan usus yang dilalui marker dengan panjang usus secara keseluruhan. Dari penelitian ini diketahui bahwa  nilai rata-rata rasio kelompok perlakuan lebih kecil dibandingkan dengan kelompok kontrol negatif (0,708).  Nilai rata-rata rasio  kelompok yang hewan mencit yang diberikan ekstrak etanol daun kelor (EEDK) dengan dosis 9,1 mg/20 g berat badan mencit adalah 0,664; kelompok dengan dosis EEDK 18,2 mg/20 g  berat badan mencit  sebesar 0,434 dan kelompok dengan dosis EEDK 36,4 mg/20 g  berat badan mencit  sebesar 0,389.  Dari nilai tersebut diketahui  ekstrak etanol daun kelor mempunyai efek antidiare melalui penghambatan motilitas usus. Efek ekstrak etanol daun kelor dalam menghambat motilitas usus paling baik pada pemberian dengan dosis 36,4 mg/20 g BB dengan nilai rata-rata rasio sebesar 0,389
Implementasi Pembelajaran Berbasis Budaya Lokal Minangkabau Pada Proyek Alek Pacu Jawi Di PAUD Al-Fa’izin Ajat, Ajat; Emelda, Emelda; Robby, Robby; Haryani, Yeni; Eliyanah, Eliyanah; Hafid, Perawati
Aksara: Jurnal Ilmu Pendidikan Nonformal Vol 10, No 1 (2024): January 2024
Publisher : Magister Pendidikan Nonformal Pascasarjana Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/aksara.10.1.327-334.2024

Abstract

This research aims to reveal the implementation of learning based on local Minangkabau culture Alek Pacu Jawi in Early Childhood Education at Al-Fa'izin PAUD Tanah Datar Regency. With this local culture-based learning, it is hoped that children can understand from an early age the noble Minangkabau values of Alek Pacu Jawi in Tanah Datar Regency. Researchers conducted direct observations and interviews at PAUD Al-Fa’izin Nagari Sawah Tangah, Pariangan District, Tanah Datar Regency. In this case the researcher chooses the right informant to obtain more accurate information. The potential of the surrounding environment is a learning resource used by PAUD Al-Fa’izin in the form of the potential of nature, culture and the surrounding community which can stimulate children's curiosity. The preparation of this local culture-based learning is based on the experience of Al-Fa'izin PAUD during its time as a pilot for the Inquiry Village Program in Tanah Datar Regency based on the elements needed in managing learning which are then integrated with the need for the introduction of local culture in early childhood in order to introduce culture and foster children's character and love of local culture.
Peran Guru Pendamping Khusus Dalam Mendukung Program Inklusi di TKIT Lentera Insan CDEC Depok Yunitasari, Septiyani Endang; Emelda, Emelda; Nofrianto, Robby; Heryani, Yeni; Eliyanah, Eliyanah; Hafid, Pera Yulia
Aksara: Jurnal Ilmu Pendidikan Nonformal Vol 10, No 1 (2024): January 2024
Publisher : Magister Pendidikan Nonformal Pascasarjana Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/aksara.10.1.347-352.2024

Abstract

Education inclusion is an approach aimed at ensuring that children with various needs receive equal and supportive education. The inclusion program at TKIT Lentera Insan CDEC Depok provides valuable opportunities for children with special needs to socialize and integrate into the school community. The role of special education teachers is crucial in creating a conducive learning environment. This article discusses the role of special education teachers in supporting the inclusion program at TKIT Lentera Insan CDEC Depok, with a focus on their efforts to ensure the success of children with special needs.
FORMULASI DAN UJI SIFAT FISIK SEDIAAN GEL EKSTRAK ETANOLIK GANGGANG HIJAU (Ulva Lactuca LINN.) Emelda, Emelda; Septiawan, Azizah Nada; Pratiwi, Dinda Ayu; Prasetya, Didik Yuni
Jurnal Insan Farmasi Indonesia Vol 3 No 2 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i2.645

Abstract

One of the skin diseases that are often experienced by people is acne. The bacteria found in acne are P. acnes, S. aureus, and S. epidermidis. The preparation was chosen in this formulation because it is more practical and durable in storage. Gel preparations were chosen because it dry easily, can form a film layer that is easy to wash, and gives a cool feeling to the skin. Physical stability tests need to be carried out to ensure the quality, safety, and usefulness of the gel so that it meets the expected specifications and is stable in storage. This study aims to make a gel formulation and determine the physical properties of green algae Ethanolic extract gel. The optimum gel formula is determined based on variations in the concentration of Hydroxypropyl methylcellulose. The Gel that meets the criteria of homogeneity, consistency, pH , and dispersibility is determined as the optimum formula. The physical stability of the optimum formula was tested by organoleptic, homogeneity, pH test, spreadability test, and viscosity test. The gel that met the acceptance criteria was green algae ethanolic extract gel with a concentration of 3% HPMC so that it was determined as the optimum formula.
HUBUNGAN RIWAYAT KERJA TERHADAP PENGETAHUAN VALIDASI DAN KUALIFIKASI BERDASARKAN CPOTB DI USAHA KECIL OBAT TRADISIONAL PT. X di DAERAH ISTIMEWA YOGYAKARTA Banafsaj, Zakia Irbah; Dwinta, Eliza; Emelda, Emelda; Sarwadhamana, Raden Jaka
Jurnal Insan Farmasi Indonesia 2023: JIFI: Webinar & call for paper
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i3.1694

Abstract

Validation and qualification are important activities the pharmaceutical industry to produce quality and safe drugs. Good Manufacturing Practices for Traditional Medicines (CPOTB) is a guideline for the traditional medicine industry to produce medicines with guaranteed quality from validation and qualifications. Employee knowledge in carrying out validation and qualifications in the traditional medicine industry is very necessary to support the production quality assurance process. The aim of the research is to determine the relationship between work history (length of work and work area) on validation knowledge and qualifications based on CPOTB in the small business of traditional medicine PT. X in the Special Region of Yogyakarta. The type of research is descriptive quantitative with a cross sectional method. The research uses primary data from questionnaires of 35 employees who work in the production sector of PT. X. The results showed that there was no work history relationship with employee knowledge of CPOTB, with a p-value of 0.496 (<0.05) in the length of work and a p-value of 0.724 (<0.05) in the work area. From the data it can be concluded that the length of work and employee work area in the production sector are not related to employee knowledge of CPOTB.
SKRINING FITOKIMIA DAN PENGARUH VARIETAS PELARUT TERHADAP KADAR ISOFLAVON RIMPANG TEMULAWAK Dilla, Triani Utami; Emelda, Emelda; Fauzi, rizal
Jurnal Insan Farmasi Indonesia Vol 7 No 1 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v7i1.1945

Abstract

Curcuma Rhizome (Curcuma xanthorriza) is a plant that is usually mixed into herbal concoctions. One of the compounds that play a role is isoflavone. This compound functions as the main antioxidant that prevents radical reactions in lipid oxidation. This research aims to conduct a phytochemical screening of Curcuma Rhizome extract to determine the effect of solvent type on the levels of isoflavone compounds. This research method is true experimental with a post-control design. Data analysis was carried out using statistical tests to see the influence of different solvents on the levels of isoflavone compounds. Based on the results of phytochemical screening, the acetone extract of Curcuma Rhizomes contains flavonoids, steroids, and tannins. However, the results were negative for alkaloid compounds. The hexane extract of Curcuma Rhizomes positively contains alkaloids, flavonoids, steroids, terpenoids, and tannins. negative results for saponin compounds. The isoflavone levels in acetone extract and Curcuma Rhizome extract were 135.32 ppm ±10.73 and 27.72 ppm ±0.86, respectively. Based on the results of the statistical analysis, it shows that there is a significant difference between the isoflavone levels of acetone extract and hexane extract of Curcuma Rhizome (Sig £ 0.05).
Inhibition Activity Of Ethanolic Extract Of Ulva lactuca Against Staphylococcus aureus emelda, emelda; Safitri, Eka Asriani; Fatmawati, Annisa
Pharmaceutical Journal of Indonesia Vol. 7 No. 1 (2021)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.pji.2021.007.01.7

Abstract

Staphylococcus aureus (S. aureus) is a normal flora that can cause mild skin infections, one of which is acne. Commonly used chemical treatments are antibiotics such as Clindamycin. Continuous use of antibiotics can lead to resistance. Natural ingredients that are possible can inhibit the growth of bacteria. Treatment caused by S.aureus is Ulva lactuca Linn. (Green algae). This marine biota contains compounds that have the potential to be antibacterial, including triterpenoids, flavonoids, and saponins. This study aims to compare antibacterial activity of  ethanolic extract of Ulva lactuca and Clindamycin against S. aureus bacteria. This type of research is an experimental laboratory. Ulva lactuca was extracted by maceration method using ethanol 96% solvent. Then carried out testing for antibacterial activity using the agar diffusion method by sump technique. The study was divided into 6 groups. One Clindamycin group and 5 treatment groups respectively with extract concentrations of 20%, 40%, 60%, 80%, and 100%. The test was carried out in 3 repetitions. Data analysis was processed by SPSS using the Kruskal-Wallis test to determine which groups had difference. The results showed that the ethanolic extract of Ulva lactuca was able to inhibit the growth of S. aureus bacteria with strong categories at concentrations of 20%, 40%, and 60%. Very strong category at 80% and 100% concentrations. The 100% concentration had the largest average inhibition zone diameter of 22 ± 0.577 mm which was not significantly different from Clindamycin with a significance value of 0.043 (p <0.05). This study concludes that the ethanolic extract of Ulva lactuca has activity in inhibiting the growth of S.aureus bacteria with strong to very strong categories, but statistically not as strong as Clindamycin
Pengaruh Pemberian Fraksi n-Heksan Ekstrak Etanol Daun Kelor (Moringa oleifera L.) Terhadap Kadar Low-Density Lipoprotein (LDL) Tikus Jantan Galur Sprague dawley : Efek Antikolestrol Fraksi n-Heksan Ekstrak Etanol Daun Kelor (Moringa oleifera L.) Kusumawardani, Nurul; Fauzi, Rizal; Emelda, Emelda; Estiningsih, Daru; Sukma Ananda , RA Dewinta; Nabila , Lathifa
Pharmaceutical Journal of Indonesia Vol. 9 No. 2 (2024)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.pji.2024.009.02.9

Abstract

This study aimed to determine the effect of the n-hexane fraction of Moringa leaf ethanol extract (Moringa oleifera L.) on low-density lipoprotein (LDL) levels in Sprague Dawley male rat strains fed a high-fat diet. This study used a pre-test and post-test control design on male rats of the Sprague Dawley strain. Thirty-six male white rats of the Sprague Dawley strain were given high-fat diet and then divided into six groups: group I was normal group, group II negative control was given CMC Na, Group III positive control was given Simvastatin 10 mg, Group IV, V, VI was given n-hexane fraction of ethanol extract of Moringa leaves (Dose 3,722 mg/kgBW; 7.444 mg/kgBW; 14,888 mg/kgBW). The results of measuring low-density lipoprotein (LDL) levels in animals were measured after 14 days of research as a post-test. Based on statistical analysis, there was no significant difference between the positive control group and the three treatment groups (p=1,000). The results of this study can conclude that the dose of the n-hexane fraction of Moringa leaves has a significant effect on decreasing LDL levels in male Sprague Dawley rats with the best % reduction at a dose of 14.89 mg/kg BW (61.17%), with a linear regression equation y=-0.0408x + 1.079; (R2=0.986). The results of this study indicate that the n-hexane part of Moringa leaves may reduce low-density lipoprotein levels in male white Wistar rats induced by high-fat.
Inhibition Activity Of Ethanolic Extract Of Ulva lactuca Against Staphylococcus aureus emelda, emelda; Safitri, Eka Asriani; Fatmawati, Annisa
Pharmaceutical Journal of Indonesia Vol. 7 No. 1 (2021)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.pji.2021.007.01.7

Abstract

Staphylococcus aureus (S. aureus) is a normal flora that can cause mild skin infections, one of which is acne. Commonly used chemical treatments are antibiotics such as Clindamycin. Continuous use of antibiotics can lead to resistance. Natural ingredients that are possible can inhibit the growth of bacteria. Treatment caused by S.aureus is Ulva lactuca Linn. (Green algae). This marine biota contains compounds that have the potential to be antibacterial, including triterpenoids, flavonoids, and saponins. This study aims to compare antibacterial activity of  ethanolic extract of Ulva lactuca and Clindamycin against S. aureus bacteria. This type of research is an experimental laboratory. Ulva lactuca was extracted by maceration method using ethanol 96% solvent. Then carried out testing for antibacterial activity using the agar diffusion method by sump technique. The study was divided into 6 groups. One Clindamycin group and 5 treatment groups respectively with extract concentrations of 20%, 40%, 60%, 80%, and 100%. The test was carried out in 3 repetitions. Data analysis was processed by SPSS using the Kruskal-Wallis test to determine which groups had difference. The results showed that the ethanolic extract of Ulva lactuca was able to inhibit the growth of S. aureus bacteria with strong categories at concentrations of 20%, 40%, and 60%. Very strong category at 80% and 100% concentrations. The 100% concentration had the largest average inhibition zone diameter of 22 ± 0.577 mm which was not significantly different from Clindamycin with a significance value of 0.043 (p <0.05). This study concludes that the ethanolic extract of Ulva lactuca has activity in inhibiting the growth of S.aureus bacteria with strong to very strong categories, but statistically not as strong as Clindamycin
Co-Authors Abd. Rasyid Syamsuri Ajat, Ajat Azizah, Abibatul Banafsaj, Zakia Irbah Dewi, Alvina Fitriya Didik Yuni Prasetya Dilla, Triani Utami Dwinta, Eliza Eliyanah, Eliyanah Estiningsih, Daru Fatmawati, Annisa Hafid, Pera Yulia Hafid, Perawati Haryanggita, Bariqna'im Katon Heriyani, Yeni Ichwan Ridwan Rais Kusumawardani, Nurul Lubis, Abdul Rahman Muhammad Abdurrahman Munir Nabila , Lathifa Nofrianto, Robby Octaviani, Ani Pothitirat, Werayut Pratiwi, Dinda Ayu Pratiwi, Sindi Priyanti, Nita Putri, Ade Lia Rahmi, Lisa Amelia Rizal Fauzi Robby, Robby Safitri, Eka Asriani Saroya, Nadia Tus Sarwadhamana, Raden Jaka Septiawan, Azizah Nada Solikah, Wahyu Yuliana Sri Watini Sukma Ananda , RA Dewinta Yeni Haryani, Yeni Yeni Heryani Yunitasari, Septiyani Endang