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Sri Agus Sudjarwo
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Department of Basic Medical Veterinary of Faculty of Veterinary Medicine, Universitas Airlangga Kampus C, Mulyorejo, Kec. Mulyorejo, Kota SBY, Jawa Timur 60115 Phone: (031) 5992785 ext. 5993016
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INDONESIA
journal of Basic Medical Veterinary
Published by Universitas Airlangga
ISSN : 23026820     EISSN : 27749959     DOI : https://dx.doi.org/10.20473
Core Subject : Health, Science, Agriculture,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Veterinary
This journal published original articles, review articles, and case studies in Indonesian or English, in the scope of JBMV has a broad coverage of relevant topics across veterinary basic medical sciences which includes: preclinical and paraclinical disciplines like Anatomy, Physiology, Biochemistry, Pathology, Microbiology, Pharmacology and Medical Education.
Arjuna Subject : Kedokteran Hewan - Kedokteran Hewan (Lain-Lain)
Articles 114 Documents
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Biofilm-Mediated Survival of Leptospira spp.: A Comprehensive Review on Molecular Basis and Control Strategies Wijayanto, Robby; Zilfiarani, Chalida Nahendra; Fahlefi, Moch. Ilham Riza
Journal of Basic Medical Veterinary Vol. 14 No. 2 (2025): Journal of Basic Medical Veterinary, December 2025
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbmv.v14i2.81120

Abstract

Leptospirosis is a significant tropical zoonosis, with a considerable burden on morbidity and mortality in humans as well as animals. One of the possible explanations is biofilm formation, which is the accumulation of EPS, eDNA, and c-di-GMP signals that respond to various environmental, antibiotic, or host-immune challenges. This review focuses on the molecular mechanisms underlying biofilm formation, ecological significance, connection to antimicrobial resistance, and the public health implications. Elucidation of the c-di-GMP regulatory networks, adhesin gene and protein expression, and other metabolic shifts account for the survival of Leptospira biofilms in autochthonous populations of aquatic habitats and kidney colonization of reservoir hosts. In addition, biofilms have been associated with long-term bacterial colonization, chronic urine stream associated with persistent bacterial shedding, and failed antibiotics. This scenario, from an epidemiological perspective, facilitates the emergence of anthropogenic infections, and perpetuates the endemic nature of the disease. From a disease-control perspective, biofilms increase the burden associated with persistent infections. This review emphasizes that, as a survival strategy, biofilms represent several potential avenues for the implementation of novel control strategies, including the use of antibiofilm agents, quorum-sensing inhibitors, and multi-epitope vaccines. The functional and integrated dissection of biofilms positioned Leptospira spp. to novel One Health-based control strategies for the disease.
Effects of Nicotine-Containing E-Cigarette Smoke on Testicular Histopathology in Albino Rats Amalia, Nina; Zhafira, Farodina Azka; Yunita, Maya Nurwartanti; Sari, Shelly Oktania Nurvita; Herdiansyah, Akbar Dimas; Pratika, Selva; Wardana, Prasvita Rosa; Zahro, Fatimatus; Rahmadani, Aurel Aulia
Journal of Basic Medical Veterinary Vol. 14 No. 2 (2025): Journal of Basic Medical Veterinary, December 2025
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbmv.v14i2.82605

Abstract

This study aims to assess the level of damage from histopathology of seminiferous tubules of testicular organs of albino rats affected by exposure to e-cigarette vapor. The 20 albino rats used were divided into 5 groups, which are the control group (C) not given exposure to e-cigarette vapor and the treatment group given exposure to e-cigarette vapor at different doses. Treatment groups T1 (0.3 mg/ml), T2 (3 mg/ml), T3 (12 mg/ml), T4 (36 mg/ml). All treatment groups were given perinhaled and the treatment was carried out for 14 days. At the end of treatment, albino rats were euthanized and then necropsied and testicular organs were preserved to make histopathological preparations using Hematoxilin-Eosin staining. The results of the histopathological picture of the seminiferous tubules of the testes were observed at 400x magnification and the thickness of the epithelium and the diameter of the seminiferous tubules. The results showed a significant change in the thickness of the seminiferous tubule epithelium in each treatment which decreased, but there was no significant change in the diameter of the seminiferous tubules. This study states that exposure to e-cigarette vapor in rats can cause a decrease in spermatogenesis.
Front Cover, Editorial Board, Peer Reviewers, Acknowledgments Aisyafalah, S.Si, Salma
Journal of Basic Medical Veterinary Vol. 14 No. 2 (2025): Journal of Basic Medical Veterinary, December 2025
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Guidelines for Author, Back Cover Aisyafalah, S.Si, Salma
Journal of Basic Medical Veterinary Vol. 14 No. 2 (2025): Journal of Basic Medical Veterinary, December 2025
Publisher : Universitas Airlangga

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Abstract

Page 12 of 12 | Total Record : 114

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