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Farisa Luthfiana
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lppmuta45@uta45jakarta.ac.id
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Fakultas Farmasi, Universitas 17 Agustus 1945 Jakarta Jl. Sunter Permai Raya, Sunter Podomoro, Jakarta 14350
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INDONESIA
SOCIAL CLINICAL PHARMACY INDONESIA JOURNAL
Published by Universitas 17 Agustus 1945 Jakarta
ISSN : -     EISSN : 25028413     DOI : https://doi.org/10.52447/scpij.v7i1
Core Subject : Health, Social,
Health Professions Medicine & Pharmacology Public Health Social Sciences
Social Clinical Pharmacy Indonesia Journal (SCPIJ) is a scientific journal managed by the Faculty of Pharmacy Universitas 17 Agustus 1945 Jakarta, which is published twice a year (April and October). SCPIJ is a scientific research journal in the field of community service with articles that have never been published online or in print before. SCPIJ aims to disseminate conceptual thoughts or ideas and research results that have been achieved in the fields of pharmacy and health, Regulatory Affairs and Pharmaceutical Marketing Research, Pharmaceutical Care,Pharmacotheraphy, Pharmacoepydemology, Pharmacogenetic, Rational Therapeutics, Evidence-Based Practice, Health Services Research, Medication Management, Drug Interactions, Drug Utilization, Drug Prescribing, Drug Information. The results of the service published in this journal are in the form of experimental and non-experimental service.
Arjuna Subject : Profesi Kesehatan - Farmasi
Articles 124 Documents
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Efektivitas Gel Ekstrak Etanol Daun Euphorbia hirta L. terhadap Penyembuhan Luka Bakar pada Kelinci rafsanjani, arief
SOCIAL CLINICAL PHARMACY INDONESIA JOURNAL Vol 11, No 1 (2026)
Publisher : Universitas 17 Agustus 1945 Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52447/scpij.v11i1.9427

Abstract

Luka bakar derajat dua merupakan cedera jaringan yang melibatkan epidermis dan sebagian dermis, sehingga memerlukan penanganan yang tepat untuk mempercepat penyembuhan serta mencegah komplikasi seperti infeksi. Pemanfaatan bahan alam sebagai alternatif terapi semakin berkembang, salah satunya daun patikan kebo (Euphorbia hirta L.) yang diketahui memiliki aktivitas antiinflamasi, antibakteri, dan antioksidan. Penelitian ini bertujuan untuk menguji efektivitas sediaan gel ekstrak etanol daun patikan kebo dalam mempercepat penyembuhan luka bakar derajat dua pada kelinci. Penelitian ini menggunakan metode eksperimental dengan rancangan post test only control group design. Hewan uji dibagi menjadi enam kelompok, yaitu kontrol positif, kontrol negatif, ekstrak 100%, serta tiga kelompok formulasi gel (Formulasi I, II, dan III). Parameter yang diamati meliputi diameter luka pada hari ke-1, 3, 6, 9, 12, dan 15 serta persentase kesembuhan luka.Hasil penelitian menunjukkan bahwa seluruh kelompok mengalami penurunan diameter luka seiring waktu, dengan tingkat penyembuhan yang berbeda. Kelompok kontrol positif menunjukkan penyembuhan tercepat dengan persentase kesembuhan 100% pada hari ke-15. Formulasi III menunjukkan efektivitas tertinggi di antara kelompok perlakuan dengan persentase kesembuhan 90% dan diameter luka 0,1 cm, mendekati kontrol positif. Sementara itu, Formulasi II, Formulasi I, ekstrak 100%, dan kontrol negatif masing-masing menunjukkan penyembuhan sebesar 80%, 70%, 65%, dan 50%.Berdasarkan hasil tersebut, dapat disimpulkan bahwa sediaan gel ekstrak etanol daun patikan kebo, khususnya Formulasi III, efektif dalam mempercepat penyembuhan luka bakar derajat dua. Sediaan gel juga terbukti lebih optimal dibandingkan ekstrak murni dan berpotensi dikembangkan sebagai terapi topikal berbasis bahan alam.
Evaluation of Dose Appropriateness in Patients Congestive Heart Failure and Comorbid Chronic Kidney Disease at RSUD Kabupaten Kediri Agustin, Ela; Fajriyah, Shofiatul; Widyaningrum, Esti Ambar; Putri, Adinda Sheisella; Wahyuni, Kumala Sari Poespita Dewi
SOCIAL CLINICAL PHARMACY INDONESIA JOURNAL Vol 11, No 1 (2026)
Publisher : Universitas 17 Agustus 1945 Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52447/scpij.v11i1.9346

Abstract

Congestive heart failure (CHF) is a chronic condition requiring long-term therapy. Patients with heart failure accompanied by comorbid chronic kidney disease (CKD) require dose adjustment to prevent drug toxicity. This study aimed to determine the therapeutic profile and dosing appropriateness among patients with congestive heart failure and comorbid CKD hospitalized at RSUD Kabupaten Kediri during the January–December 2022 period. This study employed a retrospective observational design using medical record data with a total sampling technique, resulting in 72 eligible patients. Dose appropriateness was evaluated based on estimated glomerular filtration rate (eGFR) calculated using the Cockcroft–Gault equation and compared with recommendations from The Renal Drug Handbook. The results indicate that the majority of samples in this study were female (54.17%) and aged 45–54 years (41.67%). Most patients had additional comorbidities (80.56%), with anaemia being the most prevalent concomitant condition. Based on CKD staging, the majority of patients were classified as stage 5 CKD (77.78%). Combination therapy involving two medications was the most common treatment pattern (30.57%), with a diuretic plus ARB combination being the most frequently prescribed regimen. The evaluation of dosing appropriateness demonstrated that 69 patients (95.83%) received doses adjusted appropriately to their renal function, while 3 patients (4.17%) received inappropriate dosing. Inappropriate use was identified in prescriptions of spironolactone and acarbose, which should be avoided in patients with low eGFR values. In conclusion, most patients with congestive heart failure and comorbid CKD received therapy with doses appropriately adjusted to renal function. However, cases of inappropriate dosing were still identified, which may increase the risk of adverse effects.
ANALYSIS OF DRUG-RELATED PROBLEMS (DRPs) AND THERAPEUTIC RATIONALITY IN TWO DIFFERENT CLINICAL CASES: ABDOMINAL COLIC IN ADOLESCENTS AND VERTIGO IN ADULT PATIENTS IN HOSPITALS Astiani, Rangki; Piter, Piter; Anggraeni, Ria; Ningtyas, Maria Sheila Setya; Luthfiana, Farisa; Kezia, Valerie; Borean, Mardianti
SOCIAL CLINICAL PHARMACY INDONESIA JOURNAL Vol 11, No 1 (2026)
Publisher : Universitas 17 Agustus 1945 Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52447/scpij.v11i1.9418

Abstract

ABSTRACTDrug-Related Problems (DRPs) are common issues in healthcare services and can affect the success of patient therapy. Abdominal colic is a disorder of normal intestinal flow throughout the intestinal tract caused by infection in the abdominal organs, while vertigo is a sensation that the patient is moving or spinning, or that objects around the patient are moving or spinning, usually accompanied by nausea caused by an imbalance in the three types of AKT receptors (Body Balance System) due to excessive stimulation. The purpose of this report is to review the rationality of therapy in two different clinical cases. A retrospective case study was conducted by analyzing patient medical records, DRPS analysis, physical examination, laboratory tests, pharmacological therapy, and clinical response. The first patient was given analgesic, anti-inflammatory, antibiotic, and fluid therapy for hydration. The second patient was given first-line vertigo therapy, antihypertensive drugs, and gastric protection. Therapy adjustments were made according to patient response and laboratory parameters. Clinical pharmacy monitoring ensured pain control and monitored side effects and drug interactions. 
Evaluasi Kesesuaian Terapi Terhadap Pedoman Terapi pada Pasien Rawat Jalan Diabetes Melitus Tipe 2 Dewi, Novia Ariani; Anjani, Windi; Putri, Vera Dian Apsella; Hidiyaningtyas, Lutfi
SOCIAL CLINICAL PHARMACY INDONESIA JOURNAL Vol 11, No 1 (2026)
Publisher : Universitas 17 Agustus 1945 Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52447/scpij.v11i1.9349

Abstract

Diabetes Mellitus (DM) merupakan penyakit metabolik kronis yang ditandai dengan hiperglikemia atau peningkatan kadar glukosa darah yang disebabkan oleh kelainan sekresi insulin, kerja insulin, atau kedua-duanya. Penderita DM rawat jalan di Kabupaten Sleman pada tahun 2022 menduduki peringkat kedua setelah hipertensi yaitu sebesar 5,39%. Salah satu faktor yang mempengaruhi keberhasilan terapi pada pasien DM adalah faktor terapi pasien (jumlah obat, frekuensi minum obat, dan produk obat). Dalam faktor ini, penting untuk menyesuaikan pemberian obat pada pasien dengan pedoman terapi yang digunakan. Penelitian ini bertujuan untuk mengevaluasi kesesuaian terapi yang diresepkan dokter dengan pedoman terapi yaitu PERKENI (2019) pada pasien rawat jalan DM tipe 2 di salah satu rumah sakit pada kabupaten Sleman. Sampel dalam penelitian ini adalah pasien DM tipe 2 rawat jalan pada bulan April – November 2023 yang memenuhi kriteria inklusi diperoleh 99 sampel. Jenis penelitian observasional analitik dengan metode pengambilan data secara retrospektif dengan teknik pengambilan sampel secara consecutive sampling. Hasil evaluasi kesesuaian penggunaan obat 100%, kesesuaian frekuensi penggunaan obat 97,98%, dosis obat 80,81%, jumlah obat 100%, kesesuaian golongan/nama obat 100 %. Pasien DM tipe 2 terbanyak adalah laki-laki, usia 45-59 tahun, komorbiditas pasien tertinggi adalah hipertensi, terdapat kesesuaian dibawah 100% yaitu kesesuaian frekuensi dan dosis obat.

Page 13 of 13 | Total Record : 124

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