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Krisni Subandyah
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Departemen Ilmu Kesehatan Anak FKUB (Department of Pediatrics, Faculty of Medicine, Universitas Brawijaya). Jl. Jaksa Agung Suprapto No. 2 Malang, Provinsi Jawa Timur, Indonesia
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Pediatric Sciences Journal
Published by Universitas Brawijaya
ISSN : 27220427     EISSN : 27221474     DOI : https://doi.org/10.51559/pedscij
Core Subject : Health,
Health Professions Public Health
Pediatric Sciences Journal (PedSciJ) is published by the Medical Faculty of Brawijaya University, Indonesia, as an Open Access & Peer Reviewed Multidisciplinary Journal. The aims and scope of the Journal include pediatric, neonatal healthcare, and perinatology/ The Journal aims to bridge and integrate the intellectual, methodological, and substantive diversity of medical scholarship and to encourage a vigorous dialogue between medical scholars and practitioners. The Journal welcomes contributions that promote the exchange of ideas and rational discourse between practicing educators and medical researchers worldwide. Pediatric Sciences Journal (PedSciJ) publishes peer-reviewed clinical research articles, case reports, serial case reports, systematic reviews, meta-analyses, and letters to the editor twice a year in June and December. Articles published in the Pediatric Sciences Journal (PedSciJ) embrace the full scope of the manuscript related to the health and diseases of infancy, neonates, children, adolescents, and those related to pediatric topics. The Journal also explores legal and ethical issues, neonatal technology, and product development based on COPE. The Journal’s audience includes all those that participate in perinatal/neonatal care, including, but not limited to neonatologists, perinatologists, perinatal epidemiologists, pediatricians, pediatric subspecialists, obstetrics, surgeons, neonatal and perinatal nurses, respiratory therapists, pharmacists, social workers, dieticians, speech and hearing experts, other allied health professionals, as well as subspecialists who participate in patient care including radiologists, laboratory medicine and pathologists
Arjuna Subject : Kedokteran - Pediatrics, Perinatology, and Child Health
Articles 67 Documents
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The influence of cholestasis on the direction of children's growth at Dr. Saiful Anwar Hospital, Malang Alodia Theasonia; Wibowo, Satrio; Salim, Irfan Agus
Pediatric Sciences Journal Vol. 5 No. 1 (2024): (Available online: 1 June 2024)
Publisher : Medical Faculty of Brawijaya University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/pedscij.v5i1.78

Abstract

Background: Cholestasis is a disturbance in the flow of bile that can disrupt the body's digestive and metabolic processes, especially in infants and children. Good growth during childhood is important for optimal health and development. This study aims to determine the effect of cholestasis on changes in body weight and differences in growth direction in children with cholestasis and children who do not suffer from cholestasis at Dr. Saiful Anwar Hospital, Malang. Methods: The method used was a retrospective analytical observational study with a cross-sectional design approach. The Stratified Random Sampling approach randomly selected 12 children as research samples, including children suffering from cholestasis and healthy children. The Mann-Whitney statistical test was used to assess the data and determine whether there was a difference in means between the two sample groups. Results: These findings demonstrate significant differences in growth trajectory between children affected by cholestasis and children who are free of cholestasis. Children who suffer from cholestasis tend to have more severe growth disorders, especially in terms of weight. Conclusion: These findings suggest that cholestasis conditions significantly impact children's growth.
Challenging diagnostic of juvenile systemic sclerosis in limited sources: a case report Ronaldi, Melissa; Wati, Ketut Dewi Kumara; Gunawijaya, Eka; Yantie, Ni Putu Veny Kartika; Anandasari, Pande Putu Yuli
Pediatric Sciences Journal Vol. 5 No. 1 (2024): (Available online: 1 June 2024)
Publisher : Medical Faculty of Brawijaya University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/pedscij.v5i1.88

Abstract

Background: Juvenile Systemic Sclerosis (JSSc) is a rare chronic-autoimmune rheumatic disease leading to potential delay in diagnosis, especially in limited sources due to lack of knowledge and facility. This case report aimed to present a rare case of JSSc in limited sources of medical facilities. Case presentation: A 15-year-old girl was earlier suspected of having congenital heart disease due to the presentation of bluish fingers without any detectable clinical heart disease manifestation, including normal electrocardiography as well as echocardiography. The patient experienced pain and difficulty executing wrist endorotation, representing limited joint movement action. Further physical examinations showed pale, cold fingers and toes, bluish color in the peripheral represented sclerodactyly and arthritis. Skin showed multiple erythema-hypopigmentation papuls, in accordance with gottorn papule, gottorn sign. The antinuclear antibody titer was 1:320. Chest CT-Scan result was a fibrotic line at the inferior lobe of the left lung with the left diaphragm tenting due to a chronic inflammatory process. Skin biopsy shows an acanthotic epidermis, dermafibrocollagenous tissue with extensive fibrosis, and sclerosis with vascular proliferation. These findings meet JSSc PRES, ACR, and EULAR standard classification criteria, including 1 major and 4 minors. The treatment regimen was started with methylprednisolone 2 mg/kg/day, then tapering off once clinical manifestation alleviated, methotrexate 10 mg/BSA, and folic acid 1 mg a day. Long-term monitoring plans are also scheduled. Conclusion: Recognizing early symptoms of JSSc would provide a better outcome.
Correlation Cycle Threshold (Ct) values and clinical symptoms of pediatric patients with COVID-19 Hutabarat, Andrew Partogi Hamonangan; Hutabarat, Sabar; Aurora, Wahyu Inda Dewi
Pediatric Sciences Journal Vol. 5 No. 2 (2024): Available Online : December 2024
Publisher : Medical Faculty of Brawijaya University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/pedscij.v5i2.79

Abstract

Introduction:  The COVID-19 pandemic has affected individuals of all age groups, including children. Understanding the correlation between cycle threshold values and clinical symptoms in pediatric patients with COVID-19 is crucial for accurate diagnosis and management of the disease. This research aims to determine the correlation of Cycle Threshold (CT) Values with Clinical Symptoms Of Pediatric Patients With COVID-19. Methods: This research uses quantitative design with a cross sectional study approach.  The population in this study was all children diagnosed with COVID-19 at hospitals in Jambi City in 2021. The data for this study were collected by reviewing the medical records of children registered at Jambi City Hospital who were diagnosed with confirmed cases of COVID-19.  Data analysis of this study used univariate and bivariate analysis. Result: From the characteristics of respondents, it was found that the majority of respondents were aged 11-18 years (58%) and male (58%). From the distribution of clinical symptoms, it was found that some receptors had milder symptoms (48%). The results of this study show that clinical symptoms are significantly associated with low CT values in pediatric patients with COVID-19 (p = 0.000). Conclusion: CT values show a positive correlation with clinical symptoms in pediatric patients with COVID-19. A rising Ct value might suggest a declining viral load, potentially indicating recovery.
Gastrointestinal Stromal Tumor of the Duodenum in a 13-Year-Old Girl: A Rare Case Report Rahmandita, Yushafira Putri; Hartiastuti, Setya Mithra
Pediatric Sciences Journal Vol. 5 No. 2 (2024): Available Online : December 2024
Publisher : Medical Faculty of Brawijaya University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/pedscij.v5i2.86

Abstract

Introduction: One of the main causes of death for kids and teenagers is a tumor which exceeds 200.000 in all of the world. One of the tumors is Gastro Intestinal Stromal Tumor (GIST). GIST is a mesenchymal gastrointestinal tumor with a focus on the Interstitial Cells of Cajal (ICC). Not more than 100 cases of pediatric GIST and less than 5% of childhood tumors are seen in the Gastrointestinal (GI) Tract. Due to their rarity, the current literature consists only of reviews of small case series, less than a third of all cases reported in the literature. Case Description: A thirteen-year-old girl presented to the emergency room with nausea, dizziness, and syncope a day before. She had the same complaint 2 months before and was diagnosed with iron deficiency anemia but it got worse when she came to emergency in the next two months. She got some tests and found a tubulovillous adenoma suspected as GIST in duodenal. This girl was unable to survive in the intensive unit after the surgical resection due to the massive bleeding in her stomach. Conclusion:  We reported a rare case of Gastrointestinal Stromal Tumor (GIST) of the duodenum found in a girl.
The nomenclature of duct-dependent lesions, broadening the categories for a better clinical practice AbdelMassih, Antoine; George, Acsah; Mohammad, Dima; Ansari, Fazeela; Prachith, Soumya
Pediatric Sciences Journal Vol. 5 No. 2 (2024): Available Online : December 2024
Publisher : Medical Faculty of Brawijaya University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/pedscij.v5i2.93

Abstract

Ductus arteriosus-dependent lesion includes two well-established categories, the right sided obstructive lesions such as pulmonary atresia (duct-dependent pulmonary circulation) and the left sided obstructive (duct-dependent systemic circulation) lesions ranging from hypoplastic left heart syndrome to severe preductal coarctation. Dextro-transposition of the great arteries (D-TGA) lies in a gray area, as it is considered by some old classifications as a duct-dependent pulmonary circulation lesion and by others as a new category of duct-dependent mixing lesion. We suggest adding a new functional classification, where the category of duct dependent systemic circulation/perfusion remains unchanged, and whereby duct-dependent pulmonary lesions are renamed into a broader category of duct dependent oxygenation with two sub-categories: mixing defects such as D-TGA, and defective oxygenation due to right sided obstructive lesions such as pulmonary atresia. We believe that this re-classification will cover the anatomical aspects and clinical implications of these lesions and will facilitate their management by the residents which are the primary encounter physicians in many of the developing countries.
Correlation of leukocyte count with length of hospitalization in bronchopneumonia patients Arumsari, Rizqi Amalia; Bungin, Cristian; Haikal, Sayyid Muhammad Sahil; Satriadi, Joda Isham; Ramadhanurrosita, Nia; Munif, Achmad; Mildawati, Mildawati; Amran, Andhika; Hamidah, Izdihar Nafi’u; Siahaan, Ina Uli Tondi Tarigas; Priska, Novia; Simatupang, Nurfatimah Aprillianda; Arista, Tiara; Zahra, Hanna; Tagamawan, Astra Yudha
Pediatric Sciences Journal Vol. 5 No. 2 (2024): Available Online : December 2024
Publisher : Medical Faculty of Brawijaya University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/pedscij.v5i2.98

Abstract

Introduction: Pneumonia is a disease characterized by inflammation or infection of the lung parenchyma. In the process of inflammation or infection, there are agents involved that serve as the body’s defense against infection, such as leukocytes. Leukocytes can be used as a parameter to assess the severity of the disease, which is one of the factors affecting the length of hospital stay for pneumonia patients, particularly in young children. This study aims to determine the correlation between the leukocyte count and the length of hospital stay in patients with bronchopneumonia at RSUD dr. Abdul Rivai Berau. Methods: This research was an analytical observational study with a retrospective cohort approach and used consecutive sampling for data collection. Result: The results indicate that 935 subjects meet the inclusion and exclusion criteria. Data analysis using the Pearson correlation test yielded a p-value of 0.029 and an R-value of 0.072. Conclusion: There is a correlation between leukocyte count and the length of hospital stay in bronchopneumonia patients.
Effect of gestational age on growth of low birth weight infant: retrospective cohort study Reva Audria Khairani; Tri Faranita; Yanti Harjono Hadiwiardjo; Fachri Razi Arslan
Pediatric Sciences Journal Vol. 5 No. 2 (2024): Available Online : December 2024
Publisher : Medical Faculty of Brawijaya University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/pedscij.v5i2.101

Abstract

Introduction: Growth is essential in children, especially in the first two years of life. History of low birth weight (LBW) and gestational age are known to be several factors that influence growth and relate to growth retardation. This study aims to analyze the effect of gestational age on the growth of LBW infants. Methods: An observational analytical study design with a retrospective cohort approach and quantitative study methods was conducted in September 2023. Subjects were gathered by simple random sampling. Twenty-four preterm infants and 24 full-term infants born from September 2021 to September 2022 who met the inclusion criteria were followed up. Subjects were weighed on a scale, and the results were plotted on the World Health Organization (WHO) weight-for-age growth chart. The plotted results are presented as a Z-score, which can be further categorized into two groups: severely underweight and underweight (growth not achieved), along with normal and risk of overweight (growth achieved). Result: Of the 48 subjects, the majority were male (66.67%), aged between 12-15 months (39,6%), born by cesarean section (83.3%), and had a history of exclusive breastfeeding (64.6%). Most subjects with a history of full-term and preterm LBW were in the normal category (70.8% and 75%, respectively). The result showed full-term LBW infants have 1.75 times greater risk of not achieving growth than preterm LBW with RR 1.750 (95%CI 0.588 to 5.207). Conclusion: Gestational age affects growth, with full-term infants at more risk of not achieving growth.
Challenges in the assessment and management of pain in non-verbal autistic children: a case report of an osteochondroma revealed by self-aggressive behavior Laaraje, Azzeddine; Abdelilah, Radi; Abdelhakim, Ourrai; Amal, Hassani; Rachid, Abilkassem
Pediatric Sciences Journal Vol. 5 No. 2 (2024): Available Online : December 2024
Publisher : Medical Faculty of Brawijaya University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/pedscij.v5i2.106

Abstract

Introduction: To highlight the challenges of identifying and managing pain in non-verbal autistic children through a case of osteochondroma revealed by self-aggressive behavior and to propose a structured diagnostic approach for these complex situations. Case description: We report the case of a 14-year-old girl with severe non-verbal autism spectrum disorder who developed a progressive increase in self-aggressive behavior over 20 months. The evaluation required an in-depth functional behavioral analysis and an adapted clinical examination, complemented by a radiological work-up. Behavioral analysis revealed that the function of the behavioral problems pointed towards an organic origin: an increase in behavior when moving around, a protective limping when dodging with an exacerbation in the evening. The assessment identified a femoral osteochondroma. The introduction of an alternative communication system with analgesic treatment led to an 80% reduction in self-aggressive behavior.  Our observation highlights the difficulties in identifying pain in non-verbal ASD patients and the importance of a structured diagnostic approach. The development of alternative communication appears to be a key element in the assessment and management of pain. Conclusion: Pain management in non-verbal ASD patients requires particular vigilance and a systematic diagnostic approach. Early implementation of alternative communication tools is essential to optimize their assessment and treatment.
Epicutaneous immunotherapy for peanut allergy treatment in pediatrics: A literature review Fadya, Vannisa; Safira, Siti Sarah; Nabila, Amira Qisthy; Yufika, Amanda
Pediatric Sciences Journal Vol. 6 No. 1 (2025): Available online : 1 June 2025
Publisher : Medical Faculty of Brawijaya University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/pedscij.v6i1.109

Abstract

Peanut allergy in children is a growing public health concern that significantly affects patients' quality of life. Although oral immunotherapy (OIT) has shown effectiveness in desensitizing allergic reactions, it is associated with a threefold increased risk of anaphylaxis compared to strict avoidance. As an alternative, epicutaneous immunotherapy (EPIT) has emerged as a promising therapy due to its favorable safety profile, ease of administration, and non-invasive nature. However, despite increasing interest in EPIT, there is still limited evidence assessing its efficacy and safety in pediatric populations. This literature review aims to summarize current findings on the mechanism of desensitization, clinical efficacy, safety, and impact on quality of life associated with EPIT in managing peanut allergy in children. Relevant articles were identified through database searches in PubMed, Cochrane, Science Direct, Scopus, and Google Scholar using Medical Subject Headings (MeSH) and keyword combinations such as "Epicutaneous Immunotherapy", "Peanut Allergy", and "Pediatric Allergy". EPIT works by delivering peanut allergens through a patch applied to intact skin. The allergen is taken up by Langerhans cells and presented to the immune system, triggering regulatory T-cell (Treg) responses that reduce allergic sensitivity. Viaskin© is the most clinically advanced EPIT delivery system currently available. Findings from clinical studies indicate that EPIT is effective in inducing desensitization, with a lower risk of systemic reactions compared to OIT. Furthermore, EPIT contributes to improved quality of life in children with peanut allergy. These results support EPIT as a promising therapeutic option for pediatric peanut allergy management.
The influence of intraocular pressure and accommodation amplitude on refractive status in school-age children Marzuqi, Ahmad Azhar; Abdullah, Aulia Abdul Hamid; Wulandari, Lely Retno; Anandita, Nanda Wahyu
Pediatric Sciences Journal Vol. 6 No. 1 (2025): Available online : 1 June 2025
Publisher : Medical Faculty of Brawijaya University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/pedscij.v6i1.115

Abstract

Introduction: Refraction is the ability of the eye to refract light, which is divided into 3 categories of refractive status (RS), namely emmetropia, myopia, and hypermetropia. Increasing age in school-age children is also accompanied by the development of intraocular pressure (IOP) and accommodation amplitude (AA) values, which are assumed to affect retinal sensitivity (RS). Therefore, this study aims to investigate the effects of partial and simultaneous interactions between age, intraocular pressure (IOP), and age-related macular degeneration (AA) on retinal sensitivity (RS) in school-age children. Methods: This cross-sectional study utilized 236 eyeballs from children aged ≤18 years who consented to participate and completed all eye examinations at the Al-Ikhlas Singosari Orphanage in Malang. Variables included age, IOP, AA, and RS converted into spherical equivalent (SE). Data analysis employed partial and simultaneous regression tests. Result: Partially, increased age, IOP, and decreased AA influenced myopia (6.6%, 33.3%, and 19.1%, respectively), while reduced age, increased IOP, and increased AA influenced hypermetropia (14.3%, 47.2%, and 12.2%). Simultaneously, these variables affected myopia RS by 0.6% and hypermetropia RS by 2.6%, though not significantly. Conclusion: Age, IOP, and AA show effects on myopia and hypermetropia RS both partially and simultaneously, but the influence is small and insignificant.

Page 6 of 7 | Total Record : 67

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