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<![CDATA[POTENTIALLY INAPPROPRIATE MEDICATION IN ELDERLY OUTPATIENT OF TERTIARY HOSPITAL IN INDONESIA ]]>
<![CDATA[Yosi Febrianti]]>;
<![CDATA[Eko Budi Setiawan]]>;
<![CDATA[Ninisita Srihadi]]>
<![CDATA[ Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 1 (2022): JIIS ]]>
Publisher : <![CDATA[Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin ]]>
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DOI: 10.36387/jiis.v7i1.711
<![CDATA[Increased percentage of geriatric population has an impact on more health issues. The older the geriatrics, the more susceptible they are to various physical complaints due to either natural factors or diseases. To described the prevalence of potentially inappropriate prescriptions in geriatric outpatients A retrospective, cross-sectional study was done for three months in the Medical Record Department, in one of tertiary hospitals in Indonesia. The data was analyzed using Beers Criteria 2012 and described as descriptive statistics. A total 400 prescriptions were collected in the study during the period of 3 months. The estimated prevalence of potentially inappropriate prescription use in tertiary hospitals in Indonesia reached 24.5%. The most common potentially inappropriate prescription were nonsteroidal anti-inflammatory drugs (NSAID) (17 %) and benzodiazepine (12%). NSAID was the most prescribed potentially inappropriate agents of 66 events.]]>
<![CDATA[FORMULASI DAN UJI AKTIVITAS SABUN CAIR ANTISEPTIK DARI EKSTRAK KULIT BUAH KAPUL (Baccaurea macrocarpa) ]]>
<![CDATA[Nur Mahdi]]>;
<![CDATA[Farhandika Putra]]>;
<![CDATA[Nuraini Manurung]]>
<![CDATA[ Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 1 (2022): JIIS ]]>
Publisher : <![CDATA[Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin ]]>
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DOI: 10.36387/jiis.v7i1.748
<![CDATA[Kapul fruit is a typical plant of Kalimantan known by the Latin name Baccaurea macrocarpa. The rind of Baccaurea macrocarpa has antibacterial potential, so it is necessary to develop it into liquid soap preparations. The purpose of this study was to formulate and test the antiseptic activity of liquid soap from the extract of Baccaurea macrocarpa rind. Kapul fruit peel extract was divided into 4 different concentrations (F0 0%, FI 1%, FII 2%, and FIII 3%) formulated in liquid soap preparations. The evaluation of liquid soap includes physical characteristics (organoleptic, homogeneity, dispersion test), pH, and antibacterial test. The results of the organoleptic test, dispersive test, pH, antibacterial test Kapul fruit rind extract showed no significant difference in the pH, dispersibility, and antibacterial test. Based on the results of the evaluation of the preparations, all formulas showed good characteristics. The formula I has a good antibacterial effect.]]>
<![CDATA[PENGARUH PENGGUNAAN TAS PENYIMPANAN OBAT TERHADAP KONTROL TEKANAN DARAH PASIEN HIPERTENSI ]]>
<![CDATA[Niken Larasati]]>;
<![CDATA[Sugiyono Sugiyono]]>
<![CDATA[ Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 1 (2022): JIIS ]]>
Publisher : <![CDATA[Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin ]]>
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DOI: 10.36387/jiis.v7i1.762
<![CDATA[Number of people with hypertension in Indonesia is increasing. In addition, not all patients diagnosed with hypertension are adherent to treatment. Based on the 2018 Basic Health Research data, Yogyakarta was ranked second as the province with the highest hypertension patients in Indonesia. The purpose of this study is to determine the effect of using a medicine storage bag on blood pressure control of hypertension patients. This study used a pretest and posttest design with a control group of 36 patients’ sample at the Puskesmas Gamping 1 Yogyakarta from March to August 2019. At the beginning of the study, blood pressure data of patients in both groups were taken. The intervention group was given counseling to patients with medicine storage bags. Observations were made on the results of therapy in the form of controlled blood pressure attainment. The intervention resulted in a p-value of 0.031 for systolic and 0,000 for diastolic (p-value <0.05) indicated that there was an effect of using a medicine storage bag on the control of systolic and diastolic blood pressure in hypertensive patients. This study might conclude that medication aids are useful for hypertensive patients because they can increase the achievement of therapeutic targets.]]>
<![CDATA[UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAN FRAKSI n-HEKSAN, ETIL ASETAT DAN AIR DARI SABUT KELAPA MUDA (Cocos nucifera Linn) TERHADAP Escherichia coli ESBL (Extended Spectrum Beta Lactamase) ]]>
<![CDATA[Novia Dewi Purwaningrum]]>;
<![CDATA[Lusia Murtisiwi]]>;
<![CDATA[Diah Pratimasari]]>
<![CDATA[ Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 1 (2022): JIIS ]]>
Publisher : <![CDATA[Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin ]]>
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DOI: 10.36387/jiis.v7i1.773
<![CDATA[Young coconut coir contains flavonoid compounds, phenols, tannins and saponins. The ethanol extract of young coconut coir was studied to have good antibacterial activity. This study aimed to see the inhibitory activity of ethanol extract compared fractions of young coconut coir ethanol extract in inhibiting Escherichia coli ESBL (Extended Spectrum Beta Lactamase) bacteria. Young coconut coir of extracted using 95% ethanol solvent of maceration method and patition using n-hexane and ethyl acetate solvent. Antibacterial activities using the diffusion method with concentrations of 25%, 50% and 75%. The negative control used DMSO 10%, while positve control used was chloramphenikol. Ethanol extract and fractions of ethanol extract of young coconut coir inhibited Escherichia coli ESBL bacteria. The largest radical inhibition zone was found in the ethyl acetate fraction with a concentration of 75% at 10.9 mm.]]>
<![CDATA[ANALISIS KADAR OKSALAT PADA DUA JENIS TANAMAN KALE (Brassica oleracea var. acephala dan Brassica oleracea var. palmifolia ) DENGAN METODE SPEKTROFOTOMETRI UV ]]>
<![CDATA[Emma Emawati]]>;
<![CDATA[Deden Indradinata]]>;
<![CDATA[Dina Yulia Agustina]]>
<![CDATA[ Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 1 (2022): JIIS ]]>
Publisher : <![CDATA[Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin ]]>
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DOI: 10.36387/jiis.v7i1.798
<![CDATA[Vegetables have an important function for metabolic and physiological processes in the body. Kale is dubbed as a super food because it has great health benefits. Kale contains nutrients such as vitamins A, C, potassium, calcium, iron, and manganese. Although vegetables have a lot of nutritional content, they also contain anti-nutrients, one of which is oxalic acid. Oxalic acid can irritate the intestines and can be fatal if taken in high doses, so it should be limited to 0.60-1.25 g per day. The purpose of this study was to determine the levels of oxalate in kale by UV spectrophotometry method measured at a wavelength of 351 nm. The product of the reaction is I3 which is proportional to the oxalate concentration. This research begins with method validation. The results of the validation of the calibration curve analysis method have a regression line equation y = 0.4943x + 0.244 with a correlation coefficient 0.998. The detection limit and quantization limit are 0.4018 and 1.3395. The coefficient of variance is 0.8180 and the percent recovery is 89, 92 and 101%. The results of this study showed that the oxalate content in curly kale was 0.6911 mg/100g and kale nero was 1.7045 mg/100g.]]>
<![CDATA[UJI EFEKTIFITAS SEDIAAN SPRAY GEL EKSTRAK BUNGA KENOP (Gomphrena globosa L) TERHADAP PENYEMBUHAN LUKA BAKAR ]]>
<![CDATA[Irma Novrianti]]>;
<![CDATA[Sari Wijayanti]]>;
<![CDATA[Heriani Heriani]]>
<![CDATA[ Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 1 (2022): JIIS ]]>
Publisher : <![CDATA[Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin ]]>
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DOI: 10.36387/jiis.v7i1.803
<![CDATA[A burn wound is tissue damage after contacting a heat source. Globe amaranth (Gomphrena globosa) is effective for healing burn wounds. This research analyzes the formula of spray gel pursuant to pharmaceutical requirements and the spray gel’s ability to heal burn wounds. The spray gel preparation was made from 12.5%, 15%, and 20% concentrations of globe amaranth extract. Based on the stability test, the spray gel of globe amaranth preparation is stable in storage The test of the effectiveness of globe amaranth-based gel spray for healing burn wounds was conducted on test animals divided into five groups, i.e., control positive (bioplasenton®), control negative (gel-base), FI (spray gel preparation at a 12.5% concentration of globe amaranth extract), FII (spray gel preparation at a 15% concentration of globe amaranth extract), and FIII (spray gel preparation at a 20% concentration of globe amaranth extract) and induced using an iron plate of diameter 1.5 cm. The results indicated a burn wound healing percentage of 51.33% (P%) on test animals on day 14. On FII, the P% was 62%, and FIII, the P% was 63.33% at p < 0.05. The percentage of burn wound healing on FII and FIII was the same as that on control positive at p > 0.05. To conclude, the spray gel preparation from globe amaranth extracts at 15% and 20% concentrations was effective for healing burn wounds.]]>
<![CDATA[ANALISA SENYAWA METABOLIT SEKUNDER DAN PENGARUH PEMBERIAN SERBUK SEMUT JEPANG TERHADAP KADAR KOLESTEROL PADA TIKUS PUTIH JANTAN ]]>
<![CDATA[Evi Ekayanti Ginting]]>;
<![CDATA[Cindy Fatika Sari]]>;
<![CDATA[Leny Leny]]>;
<![CDATA[Parhan Parhan]]>;
<![CDATA[Pricella Ginting]]>
<![CDATA[ Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 1 (2022): JIIS ]]>
Publisher : <![CDATA[Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin ]]>
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DOI: 10.36387/jiis.v7i1.809
<![CDATA[This study aimed to examine the anticholesterol activity of Japanese ant powder on male white rats of the Wistar strain. This research was conducted experimentally with the method of pre-test and post-test with control group design. The negatif control was given Na-CMC 1%, the positive control was simvastatin 10 mg/kgBW, and the Japanese ant powder treatment group was given a dose of 100 mg/kgBW, 200 mg/kgBW and 300 mg/kgBW. The treatment of rats was given orally. Total cholesterol levels were measured in rat blood serum by the enzymatic CHODPAP method. Measurement of total cholesterol levels was carried out on the 15th and 22nd days using a microlab 300 photometer. The results showed that Japanese ant powder had anticholesterol activity. The percentage of cholesterol reduction in positive control was 59.75%, Japanese ant powder dose of 100 mg/kgBW was 41.79%, dose of Japanese ant powder 200 mg/kgBW was 48.72% and 300 mg/kgBW was 53.83%. The results of the ANOVA test showed a significant difference with a p value <0.05. The conclusion of this study is that Japanese ant powder has activity in reducing cholesterol levels in male white rats and the effective dose is 300 mg/kgBW.]]>
<![CDATA[PENINGKATAN FOTOSTABILITAS PIGMEN BETA KAROTEN DENGAN PEMBUATAN MIKROEMULSI ]]>
<![CDATA[Ika Agustina]]>;
<![CDATA[Mega Efrilia]]>
<![CDATA[ Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 1 (2022): JIIS ]]>
Publisher : <![CDATA[Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin ]]>
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DOI: 10.36387/jiis.v7i1.823
<![CDATA[Sepanjang tahun 2018 BPOM menemukan berbagai macam kosmetik illegal yang mengandung bahan dilarang/bahan berbahaya. Salah satu bahan berbahaya yang ditemukan adalah pewarna tekstil Merah K3 pada lipstick. Solusi yang diperlukan adalah dengan membuat pewarna alami yang memiliki kestabilan yang baik terhadap cahaya. Tujuan penelitian ini adalah untuk meningkatkan kestabilan pigmen beta karotenoid terhadap cahaya dengan membuat sediaan mikroemulsi. Sumber senyawa beta karoten berasal dari Daucus carota L. Teknik ekstraksi menggunakan maserasi dengan pelarut etanol:heksana (4:3). Untuk mendapatkan formulasi mikroemulsi terbaik dibuat variasi konsentrasi PEG 40 HCO:gliserol:ekstrak. Formulasi mikroemulsi terbaik adalah kode FW3 dengan komposisi 2:2:1 (PEG 40 HCO:gliserol:ekstrak). Kemudian ekstrak Daucus carota L dan mikroemulsi FW3 diuji fotostabilitas. Hasil pengujian fotostabilitas menunjukkan penurunan kadar ekstrak Daucus carota L. sebesar 2.84%, sedangkan mikroemulsi Daucus carota L mengalami penurunan kadar sebanyak 1.33%. Kedua sediaan tetap dikategorikan sebagai substansi yang fotosensitif.]]>
<![CDATA[PEMENUHAN OBAT COVID-19 DI INSTALASI FARMASI PROVINSI KALIMANTAN SELATAN ]]>
<![CDATA[Laeliyatun Ikrimah]]>;
<![CDATA[Abdul Rahem]]>;
<![CDATA[Anita Purnamayanti]]>
<![CDATA[ Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 1 (2022): JIIS ]]>
Publisher : <![CDATA[Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin ]]>
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DOI: 10.36387/jiis.v7i1.826
<![CDATA[Covid-19 pandemic has not ended and reach its peak in July 2021. The handling of this pandemic is carried out with logistical support for treatment as therapy. Antivirus and antibiotic widely used are Oseltamivir75mg, Favipiravir 200mg and Azithromycin500 mg. The purpose of this study was to determine the need and fulfillment of these medicines in 13 cities and health facilities in South Kalimantan. This study uses observational methode with a total sample of the need and fulfillment of these drugs in July 2021 at IFP South Kalimantan which includes IFK in 13 cities and health facilities that serve the handling of COVID-19. The method of analysis used is descriptive analysis with the most usage and the average percentage fulfillment of needs.The result showed that IFP South Kalimantan could meet about 51,35% of the need for Oseltamivir 75mg, 65,71% for Favipiravir 200mg and 38,68% Azithromycin 500mg from the total needs of 13 cities in South Kalimantan. The most commonly used oseltamivir 75mg and azithromycin 500mg were IFK Banjarmasin, Tanah Bumbu and Kotabaru. This indicates that Covid-19 severity was mild in that cities. The most use of favipiravir is Ulin Hospital, Idaman Hospital and Ansari Shaleh Hospital as 3 referral hospitals in the cities of Banjarmasin and Banjarbaru. It is indicate of moderate to severe COVID-19 that requiring hospital treatment. Conclusion of this study are the fullfill of Favipiravir 200mg and Oseltamivir 75mg are more than 50% of IFK need in 13 cities.]]>
<![CDATA[EVALUASI POLA PERESEPAN PADA PASIEN LANJUT USIA MENGGUNAKAN WHO PRESCRIBING INDICATORS ]]>
<![CDATA[Mia N. A. Fatin]]>;
<![CDATA[ED. Y.M. Pasha]]>;
<![CDATA[Khairunnisa Fadhilah]]>;
<![CDATA[Vera L. Fitriani]]>
<![CDATA[ Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 1 (2022): JIIS ]]>
Publisher : <![CDATA[Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin ]]>
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DOI: 10.36387/jiis.v7i1.827
<![CDATA[Older patients are very susceptible to drug use problems. Drug use problems are related to physiological conditions that affect the pharmacokinetics and pharmacodynamics of the drug. This study aimed to evaluate drug prescribing pattern in older patients at Pasundan Health Center Bandung. Data were retrospectively collected from prescriptions from March to June 2021. The pattern of prescribing drugs was evaluate using the WHO prescribing indicator with five indicators: the number of drugs per prescription, antibiotic use, generic drugs, the percentage of injection preparations, essential drug use. A total of 638 prescriptions met the inclusion criteria. The average number of drugs per prescription is 2.8. The prescription drugs from a total of 1.777 drugs in the form of generic drugs amounted to 83.29%, and essential drugs amounted to 74.28%. The antibiotics and injection use percentage were 11.82% and 0%, respectively. The most frequently prescribed antibiotics were amoxicillin, clindamycin, ciprofloxacin, betamethasone, and miconazole. The most frequently prescribed drugs were amlodipine, paracetamol, diclofenac sodium, chlorpheniramine maleate, and multivitamins. The use of essential and generic drugs was below WHO standard, while the average number of drugs per prescription was above WHO standard.]]>
