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Contact Name
Siska Musiam
Contact Email
siska@stikes-isfi.ac.id
Phone
+62511-3301610
Journal Mail Official
jiis@stikes-isfi.ac.id
Editorial Address
Jl. Flamboyan III/7c Kayu Tangi 70123 Banjarmasin Kalimantan Selatan
Location
Kota banjarmasin,
Kalimantan selatan
INDONESIA
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan
ISSN : 2502647X     EISSN : 25031902     DOI : https://doi.org/10.36387/jiis
Core Subject : Health,
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIIS is a forum for the publication of quality and original works that open discussions in the field of pharmacy and health sciences.
Articles 429 Documents
KUALITAS HIDUP PASIEN KANKER PAYUDARA DI RUANG EDELWEIS RSUD ULIN BANJARMASIN Erna Prihandiwati; Melia Digna Pratiwi; Noverda Ayuchecaria; Novia Ariani; Noor Aisyah; Mardiana Mardiana
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (131.476 KB) | DOI: 10.36387/jiis.v4i1.289

Abstract

Breast cancer is the biggest problem for women around the world and causes a major death for patients with breast cancer. Breast cancer and its treatment or side effects of treatment are often associated with a decrease in the quality of life of breast cancer patients. In Indonesia, the prevalence of cancer / tumor is quite high at 1.4 per 1000 population, or about 330,000 people. The purpose of this study was to determine the quality of life of breast cancer patients in the edelweiss room of Ulin Banjarmasin Public Hospital. This research is a descriptive non-experimental research. The study was conducted at Ulin Banjarmasin Hospital in the period of July-August 2018. The sampling method used was consecutive sampling. The study population was 85 breast cancer patients and the study sample was all of the population because the entire population met the inclusion criteria. The instrument used was the European Quality Of Life - 5 Dimension questionnaire and the EQ-5D Index Calculator by using the Japanese state to calculate the score for each item of question on the EQ-5D-3L questionnaire. The result of this research is the description of the quality of life in 85 research respondents as much as 57.7% had a good quality of life and as much as 42.3% had poor quality of life.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL 96% RIMPANG LENGKUAS MERAH (Alpinia purpurata (Vieill.) K.Schum) TERHADAP BAKTERI Staphylococcus aureus Rakhmadhan Niah; Saftia Aryzki; Anna Khumaira Sari; Shela Puzi Dina
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (170.045 KB) | DOI: 10.36387/jiis.v4i1.290

Abstract

Alpinia purpurata (Vieill.) K.Schum contains flavonoids, tannins, saponins, and terpenoids which have bacterial inhibitory power. This study aims to determine the antibacterial activity test of ethanol extract 96% Alpinia purpurata (Vieill.) K.Schum on the growth inhibition power of Staphylococcus aureus. This research is an experimental research. Antibacterial activity test of extract ethanol 96% Alpinia purpurata (Vieill.) K.Schum using Cup Plate Technique with concentrations of 40%, 30%, 20%, 10% and 5%, Clindamycin concentration 50μg/ml as control (+) and 96% ethanol as control (-) in each treatment replication 4 times. The results diameter of the inhibitory zone formed was then analyzed by Statistical Producy Service Solution (SPSS) version 17. The results showed that extract ethanol 96% of Alpinia purpurata (Vieill.) K.Schum had inhibitory activity on the growth of Staphylococcus aureus. The average diameter of the extract ethanol 96% inhibition zone of Alpinia purpurata (Vieill.) K.Schum with a concentration of 40%, 30%, 20%, 10% and 5%, positive control (clindamycin), and negative control (96% ethanol) respectively on Staphylococcus aureus bacteria is 28.06 mm; 25.17 mm; 23.15 mm; 20.38 mm; 18.34 mm; 30.13 mm; 0 mm. There are significant differences in diameter of inhibitory zones between concentrations of extract ethanol 96% of Alpinia purpurata (Vieill.) K.Schum on the growth of Staphylococcus aureus bacteria with significance values 0,000.
PENGARUH EKSTRAK AIR KULIT BUAH PISANG AMBON (Musa paradisiaca L.) PADA MODEL HEWAN RESISTENSI INSULIN Elis Susilawati; Nita Selifiana; Sinta Paramudita Supriana
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 1 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (116.682 KB) | DOI: 10.36387/jiis.v5i1.307

Abstract

Ambon banana (Musa paradisiaca L.) is one kind of banana that its peel has activities as antioxidant. It can control glucose level of blood and preventing complications in diabetes mellitus. This research was aiming to evaluate the effect of banana peel water extract in the decreased blood glucose levels and determining the effective dose in increasing the value of KTTI. This research was done by using animal as a model for insulin resistance, that was induced by lipofundin and fructose oraly during 28 days. Animal’s used were 30 male mice swiss Webster. It was divided into six groups, that were negative control, positive control, standard drug group of Metformin 65 mg/Kg bw, banana peel water extract with the dose 100 mg/Kg bw, 200 mg/Kg bw and 400 mg/Kg bw. The parameter was blood glucose level and KTTI by giving insulin 0,0125U/Kg bw intraperioteneally. The result showed that banana peel water extract with the dose 400 mg/Kg bw was the effective dose with the value of KTTI 1,16.
POTENSI EKSTRAK KULIT LIMAU BANJAR (Citrus reticulata) DENGAN METODE DPPH SEBAGAI ANTIOKSIDAN Bela Ghonim Nashucha; Rakhmadhan Niah; Lutfi Anggraini; Winola Exliscia
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 2 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (250.313 KB) | DOI: 10.36387/jiis.v4i2.323

Abstract

Free radicals are a factor that causes various degenerative diseases to occur. Degenerative diseases have become the biggest cause of death in Indonesia, such as cancer, diabetes, heart disease and premature aging. The body needs an important substance to help protect against attacks by free radicals that work by reducing the negative effects of these compounds, namely antioxidants. Natural antioxidants can be obtained through the consumption of herbal plants that contain secondary metabolites of antioxidants, such as banjar orange peel (Citrus reticulata). The aim of this study was to determine the antioxidant activity of banjar orange peel extract which was expressed by inhibitors Consentration 50 (IC50). The banjar orange peel was extracted by maceration method using aquadest solvent and antioxidant activity was tested using the DPPH (1,1-diphenyl-2-picrylhydrazly) method by UV-Vis spectrophotometry at a wavelength of 517 nm. The results showed that the banjar orange peel contained antioxidants which were 10 ppm (29,814%), 20 ppm (35,182%), 30 ppm (43,482%), 40 ppm (50,022%), 50 ppm (58,682%) with IC50 values ​​of 39,041 ppm which is included in the range of very strong antioxidant activity. The conclusion of the study is that the banjar orange peel extract has the potential to be developed as a source of natural antioxidants for humans.
UJI VALIDITAS DAN RELIABILITAS KUESIONER KEPATUHAN MGLS (MORISKY, GREEN, LEVINE ADHERENCE SCALE) VERSI BAHASA INDONESIA TERHADAP PASIEN EPILEPSI Iin Ernawati; Wardah Rahmatul Islamiyah
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 2 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (251.407 KB) | DOI: 10.36387/jiis.v4i2.330

Abstract

Epilepsy is a chronic brain disease that is characterized by seizures spontaneously, recurs and there is no improvement in each seizure. One measure of therapy epilepsy is decreased or loss of seizures. One of the things that still causes the uncontrolled seizure is adherence. Measurement of adherence in epilepsy patients is one of the tool for know related to the type of therapy and intervention provided. One of the adherence questionnaires that can be used is MGLS (Morisky, Green, Levine Scale Adherence Scale). The MGLS questionnaire is a adherence questionnaire with 4 items of questions, where the questionnaire questions can describe the level of patient adherence in drug consumption. The purpose of this study is to test the validity and reliability of the MGLS questionnaire with the intention that the questionnaire can be applied to patients.This study was a descriptive observational study conducted on epilepsy patients at Airlangga University Hospital. Sampling was done through consecutive sampling method, obtained 42 epilepsy patients between May-July 2018. Validity test was carried out using the Pearson correlation method (correction value ≥0.3) and the reliability test using internal cronbach alpha coefficient ≥0.6. Based on the results of the validity test it is known that the correlation score of each question with the total score is known to correlate more than r table (N = 42) 0.3496. These results indicate that all questions on the Indonesian version of the MGLS questionnaire are valid. Reliability test showed cronbach alpha coefficient 0.634> 0.6 (p <0.05). The conclusion of this study is the valid and reliable MGLS Indonesian version of the questionnaire instrument to determine the level of adherence in epilepsy patients.
IDENTIFIKASI DAN MOLECULAR DOCKING KOMPONEN UTAMA MINYAK KULIT BUAH JERUK NIPIS SEBAGAI AGEN ANTIKANKER Indah Hairunisa; Normaidah Normaidah; Sylvan Septian Ressandy; Fhirda Azhari
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 2 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (233.306 KB) | DOI: 10.36387/jiis.v4i2.338

Abstract

Cancer is the highest cause of death in the world. This disease is known to have different regulations from other diseases. The development of drugs today is to target anticancer drugs on cancer regulation sites at Hallmark of Cancer. Lime (Citrus aurantifolia) is one type of Citrus (orange) which contains beneficial chemical compounds and active as anticancer agents. Lime peel is known to have bioactive content in the form of essential oils and flavonoids such as hesperidin and hesperitin. The content of this compound is closely related to anticancer activity. This study aims to identify the content of compounds in lime peel oil and the study of molecular docking silico in these compounds in protein that play a role in the regulation of cancer cells. Lime peel oil is obtained using the steam distillation method then analyzed using GC-MS to determine its constituent components to be analyzed in silico then using YASARA 10.1.8, MarvinSketch 15.4.20, and PLANTS software. The results showed that the main components of lime peel oil were d-limonen and beta-pinen with a percentage of 59.71% and 36.81%. In silico analysis shows that each of these compounds has an affinity greater than the native ligand on caspase-8 proteins (protein regulation of apoptosis). Based on these results it can be concluded, that the lime peel oil has the potential to be developed as an anticancer agent.
POTENSI KOMBINASI KAPUR SIRIH DAN DAUN KUMPAI MAHUNG (Eupatorium inulifolium H.B&K.) SEBAGAI ALTERNATIF SALEP ANTI INFLAMASI ALAMI Dwi Rizki Febrianti; Siska Musiam
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 2 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (212.251 KB) | DOI: 10.36387/jiis.v4i2.339

Abstract

Kumpai Mahung (Eupathorium inulifolium H.B & K) is one of an endemic plant in South Kalimantan. Hereditary used as traditional medicine. kapur sirih (calcium carbonate) is also used by the community as a food additive (BTP), especially in the manufacture of chips and fruit ice. Traditionally these two ingredients are combined to treat swollen (oedema) mastitis in nursing mothers. This research method using raw test pad oedema in legs male rats. simple ointment dosage form, induction carrageenan 3% and hydrocortisone as a positive control anti-inflammatory calculated the value and the value AUC (area under the curve). the results expressed Ointment combination Kumpai Mahung leaf extract and calcium carbonate have anti-inflammatory power of 14.91% greater than the positive control 9.95%.
ANALISIS KANDUNGAN FORMALIN PADA CABE MERAH GILING YANG DIJUAL DI PASAR TRADISIONAL KOTA JAMBI Havizur Rahman; Dika Zamri Yanni; Putri Maya Sari; Mia Prajuwita; Intan Lestari
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 2 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (323.065 KB) | DOI: 10.36387/jiis.v4i2.341

Abstract

Research has been conducted to analyze the presence of formaldehyde content in ground red chili which is sold in the traditional markets of Jambi city. The milled red chili samples were obtained from 5 markets and each market was chosen by 5 milled red chili traders. Stages in this study include sample preparation, a qualitative test of formaldehyde content using chromatophenic acid reagents, and quantitative analysis of formalin using UV-Vis spectrophotometer at a wavelength of 566 nm. The results of this study showed 6 of the 25 samples identified to contain formalin. Qualitative analysis with chromatophenic acid reagents showed a change in color to brown. Formalin levels for positive samples included A2 samples at 0.54 g / kg, B4 at 0.74 g / kg, C2 at 0.56 g / kg, D3 at 0.65 g / kg, E3 at 0.53 g / kg, and E4 of 0.65 g / kg. It can be concluded that the discovery of formaldehyde content in ground red chili at several points in the traditional markets of the city of Jambi.
EFEKTIVITAS DAUN RAMANIA ASAL KALIMANTAN SELATAN UNTUK MENURUNKAN KADAR GULA DARAH Saftia Aryzki; Yugo Susanto
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 2 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (230.866 KB) | DOI: 10.36387/jiis.v4i2.342

Abstract

Ramania or Gandaria is a swamp plant in the area of South Kalimantan from one of the mango families that is not cultivated by the community, the types are diverse, including fruit size, flavor, and color. Ramania leaves have properties to reduce blood sugar levels. High blood sugar levels are a manifestation of diabetes mellitus. The purpose of this study was to determine the effectiveness of ramania leaf extract as a decrease in blood sugar levels with the oral glucose tolerance test (TTGO) method. This study was a true experimental with a pre-post test design with randomized control group design. The stages of the research method were carried out with a preliminary stage and an antidiabetic activity test stage with an oral glucose tolerance test (TTGO) method with Sprague Dawley strain male rats. The results of the research that have been done can be concluded that the extract of ramania leaf (Bouea macrophylla Griffith) can reduce the blood sugar levels of white mice (Mus muscullus) which are induced by alloxan. The dose used in this study was the lowest dose 0.455 mg / 200 kg body weight, treatment group 2 (P2) with moderate dose (usual use dose) 0.91 mg / 200 g body weight, and treatment group 3 (P3) with high dose 1, 82 mg / 200 g BW. Of the three groups approaching positive control, P3 with blood sugar levels after 14 days of treatment was 77.08 mg / dL and 77.79 mg / dL, respectively.
OPTIMASI KONDISI SINTESIS NANOPARTIKEL TEMBAGA MENGGUNAKAN EKSTRAK BIJI MELINJO (Gnetum gnemon L.) Hilda Aprilia Wisnuwardhani; Arinda Roosma; Yani Lukmayani; Anggi Arumsari; Sukanta Sukanta
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 2 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (325.202 KB) | DOI: 10.36387/jiis.v4i2.343

Abstract

Copper nanoparticles (CuNPs) is one of metal nanoparticles, which have many benefits especially in medicinal science. The aim of this research is to determine CuNPs synthesis optimum condition using melinjo seed extract as a bioreductor. In this work, copper (II) sulphate pentahydrate is used as a precursor. Melinjo seed extract was prepared at 600C using aquadest as a solvent. Two stabilizers were used i.e. β-cyclodextrin (BCD) and citric acid. The result showed that the optimum ratio condition of CuNPs synthesis is extract: CuSO4 1 mM: β-cyclodextrin 10 mg/mL = 1:1:1 (v/v/v). The CuNPs were synthesized by reflux method at 900C for 4 hours. It was observed that the addition of sonication process for 2 hours affected the stabilization of CuNPs. The average size of particles is 364,1 nm in diameter and 0,296 in polydispersity index.