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Erina Yatmasari
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Oceana Biomedicina Journal
Published by Universitas Hang Tuah
ISSN : -     EISSN : 26140519     DOI : https://doi.org/10.30649/obj
Core Subject : Health,
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health
Oceana Biomedicina Journal is an open access journal of health and medicine. Specifically, the journal focuses on marine medicine, hyperbaric medicine and health, medicine on ships, harbor health, maritime and coastal health, medicolegal studies related to ships, ports and districts, maritime/coastal communities and fishermen, epidemiological aspects of diseases, disabilities and disorders that occur on ships and affect boat workers, ports and maritime zones, coastal areas, fishermen communities and their families, including pharmacological and non-pharmacological prevention and treatment management policies; and miscellanous.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 51 Documents
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Utilization of Mesenchymal Stem Cells in Therapy in the Oral Cavity Vinna Kurniawati Sugiaman
Denta Journal Kedokteran Gigi Vol 2 No 2 (2019): Oceana Biomedicina Journal Volume 2 Issue (No) 2 July - December 2019
Publisher : Universitas Hang Tuah

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Abstract

Therapy by using stem cells has recently been considered a scientific breakthrough for the world of medicine and dentistry, and is considered an important weapon in combating various diseases. Mesenchymal stem cells are cells that have the ability to renew themselves, are multipotent, capable of differentiating and proliferating, and are immunosuppressive, so that they can be used to repair and regenerate various tissues through regenerative therapy. The purpose of this paper is to provide a brief overview of various sources of stem cells and the latest findings and also their implications for improving the health of the oral cavity through regeneration of various tissues in the oral cavity. The use of mesenchymal stem cells in the field of dentistry is considered that the new era of dentistry is being started and is expected to change the paradigm in carrying out treatment of diseases in the oral cavity. Mesenchymal stem cells can be isolated from various tissues that can be used in regenerative therapy through tissue engineering to repair and regenerate tissue in the oral cavity. In utilizing this technology, stem cells, regulators, and matrices are needed as a framework that can facilitate cells to cling to, differentiate, proliferate, form matrices, and increase specific interactions between cells. Conclusions, mesenchymal stem cells can be used in regenerative therapy in the oral cavity to repair and regenerate damaged tissue through tissue engineering technology.
Manalagi Apple Vinegar (Malus sylvestris Mill) as Anti Diabetic to Alloxan Induced Wistar White Male Rat Valentina Verrel Purnomo; A. Sareh Arjono Tjandra; Risma Risma
Denta Journal Kedokteran Gigi Vol 2 No 1 (2019): Oceana Biomedicina Journal Volume 2 Issue (No) 1 January - June 2019
Publisher : Universitas Hang Tuah

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Apple vinegar is estimated to be able to cure diabetes. Vinegar is able to control the increase of glicemic index. Apple has antioxidant substance such as quercetin and chlorogenic acid. Manalagi apple could be found easily in Indonesia.This research aims to reveal the effect of Manalagi apple vinegar (Malus sylvestris Mill) towards blood glucose level of alloxan induced Wistar white male rats (Rattus norvegicus).This research is experimental laboratory using Experimental methods. The samples are 30 white rats divided into three groups for 31 days, 1) group which only given standard diet; 2) group that induced by 120mg/dL alloxan; 3) group that induced by 120mg/dL alloxan and Manalagi apple vinegar 0.27ml/100gram weight for 14 days. The measurement of blood serum glucose level is done on day twenty four using homogenous colorimetric enzymatic test method for all groups.Blood glucose average in group with only given standard diet as negative control group (182.33 mg/dL), group which induced by 120mg/dL alloxan as positive control group (205.2 mg/dL), group which induced by 120mg/dL alloxan and Manalagi apple vinegar as treatment group (212.25 mg/dL). The result of One-Way Anova significance is 0.229.The conclusion of this research is that Manalagi apple vinegar treatment doesn’t able to decrease the blood glucose level of white Wistar male rats significantly.
Comparison of Anxiety Level on Medical Skill Examination Between Students of Medical Faculty of Hang Tuah University Surabaya in 1st Semester Who Have Received Mental Health Tests During The Entrance Test with 3rd Semester Who Have not Received A Mental H Edwin Timotius Martua Marpaung; Sadya Wendra; Edward Imanuel Simon
Denta Journal Kedokteran Gigi Vol 2 No 1 (2019): Oceana Biomedicina Journal Volume 2 Issue (No) 1 January - June 2019
Publisher : Universitas Hang Tuah

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Abstract

Anxiety is an unpleasant feeling of insecure tension and fear that arises because it feelssomething will happen that is disappointing but the source is largely unaware by theperson concerned. Various studies have shown a high frequency of anxiety symptomsin medical students.The aim of this study is knowing the comparison of the level of anxiety to the medicalskills test between students of Medical Faculty of Hang Tuah University Surabaya in 1STsemester who have received mental health tests during the entrance test with 3RDsemester who have not received a mental health test during the entrance test.This study was an observational analytic study with a cross-sectional study design. Thesampling technique used in this study is stratified random sampling. The population inthis study were the first and third semester students of the Medical Faculty of HangTuah University Surabaya in the 2017/2018 school year, while the samples taken were374 students meeting the inclusion criteria, Assessment of anxiety levels was carriedout using the Hamilton Rate Scale for Anxiety (HRSA) questionnaire.Mild anxiety levels are more numerous in first-semester students (75%) compared tothird-semester students (50%), while moderate-to-severe anxiety levels are morenumerous in third-semester students (40%) compared to first-semester students(12.5%) who have received mental health tests during the entrance test. This study concluded there is a difference of ansiety level on medical skill examinationbetween students of medical faculty of Hang Tuah University Surabaya in 1st semesterwho have received mental health tests during the entrance test with 3rd semester whohave not received a mental health test during the entrance test.
Pengaruh Pemberian Terapi Oksigen Hiperbarik 2,4 ATA terhadap Kadar C-Reactive Protein (CRP) Darah Mencit Model Rheumatoid Arthritis Thalia Tamara; Hendrata Erry Andisari; Totot Mudjiono
Denta Journal Kedokteran Gigi Vol 2 No 2 (2019): Oceana Biomedicina Journal Volume 2 Issue (No) 2 July - December 2019
Publisher : Universitas Hang Tuah

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Abstract

Background: Rheumatoid Arthritis (RA) is an autoimmune disease with an increasingprevalence from year to year. RA mortality continues to increase in the last 1 decade due tothe absence of effective prevention and therapy. Hyperbaric oxygen therapy can be anadjuvant therapy for Rheumathoid Arthritis.Objective: This study uses Hyperbaric Oxygen Therapy to reduce the inflammatory reactionin patients with Rheumatoid Arthritis.Method: Samples used are 16 male balb/c mice, divided into 2 groups, 1) group of inducedexperimental animals as models of Rheumatoid Arthritis 2) group of induced experimentalanimals as models of Rheumatoid Arthritis and given 3x30 minutes of 2.4 ATA hyperbaricoxygen therapy for 10 consecutive days. On 59th day, ELISA screening test is performed forC-ReactiveProtein measurement.Result: The average results of C-Reactive Protein levels between 2 groups, are, the group ofmice with rheumatoid arthritis model that was not treated with HBO therapy had an averageCRP level of 0.204 Pg / ml, while the group of mice with rheumatoid arthritis model which istreated with HBO therapy has a mean CRP level of 0.113 Pg / ml.Conclusion: There is an effect of hyperbaric oxygen therapy to C-Reactive Protein level inmice with rheumatoid arthritis model.
Analisis Kalsium (Ca) pada Ikan Petek dan Mujair dengan Metode Kompleksometri Azmalina Adriani; Fauziah Fauziah; Riki Saputra
Denta Journal Kedokteran Gigi Vol 2 No 2 (2019): Oceana Biomedicina Journal Volume 2 Issue (No) 2 July - December 2019
Publisher : Universitas Hang Tuah

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Fish is one of the example of a comestibles that contains a lot of protein and minerals, one ofwhich is calcium. Calcium functions for the body's metabolism in the bone and toothformation. Petek and Mujair fish contain calcium that is needed by the human body.The purpose of this study was to determine the levels of calcium contained in Petek andMujair fish.The sampling was done by purposive sampling, which the sample used was obtained by themarket in the Peunayong Banda Aceh. This research used complexometry methods. Thesamples of Petek and Mujair fish that had been cleared were titrated using Na2-EDTA as thetitrator.The result showed that Petek and Mujair fish had different calcium levels where the calciumlevels in Petek fish reach an average of 0.853% and the calcium levels in Mujair fish reachan average of 0.616%. Petek fish had higher calcium levels than Mujair fish, it was causedby their habit, where Petek fish was sea fish that contained fat, vitamins and minerals, whileMujair fish was freshwater fish that contained carbohydrates and proteins.
Detection of genes encoding ompW and ctxA of Vibrio cholerae isolated from shrimp and shellfish at Kedonganan fish market, Bali-Indonesia Rian Ka Praja; I Dewa Made Sukrama; Ni Nengah Dwi Fatmawati
Denta Journal Kedokteran Gigi Vol 2 No 1 (2019): Oceana Biomedicina Journal Volume 2 Issue (No) 1 January - June 2019
Publisher : Universitas Hang Tuah

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Contamination of pathogenic bacteria in food can lead to the emergence of foodborne disease. One of foodborne disease which often occurs in some developing countries such as Africa, Southeast Asia, and Latin America is cholera which is caused by Vibrio cholerae. The disease is transmitted through beveragesand food, especially contaminated seafood. V. cholerae has several virulence factors including the outer membrane protein W (ompW) and cholerae toxin (ctx).The ompWacts as a protective barrier and can also be used as a marker specific species of V. cholerae and cholerae toxin is an enterotoxin responsible for the incidence of diarrhea in a cholera outbreak produced by pathogenic V. cholerae. This study was an observational study to determine the level of contamination of V. cholerae by detecting the outer membrane protein W (ompW) and cholerae toxin subunit A (ctxA)gene of V. cholerae in shrimp and shellfish sold at Kedonganan fish market. Samples were taken using total sampling technique and obtained 24 samples consisting of 14 shrimp samples and 10 shellfish samples. Samples were examined using culture methods and biochemical tests, and then further tested using Duplex Polymerase Chain Reaction (dPCR) to detect ompW and ctxA gene. The dPCR assay results showed 8 out of 14 (57.1%) samples from shrimp and 1 out of 10 (10%) samples from the shellfish positive carried ompW gene, and found no positive samples carrying the ctxA gene in samples derived from shrimp and shellfish. Chi square test analysis results indicated contamination of V. cholerae in shrimp washigher than shellfish based on ompW gene (p<0.05). It can be concluded that the shrimp and shellfish at Kedonganan fish market are contaminated by V. cholerae. Further research is needed to detect the virulence factors besides ompW and ctxA ofV. cholerae in seafood.
Perbedaan Pandangan Positif Atau Negatif terhadap Pasien Gangguan Jiwa Antara Mahasiswa Fakultas Kedokteran Universitas Hang Tuah Surabaya Semester 5 dengan Semester 7 Fifin Yulia Candra Pangestika; Sadya Wendra; Edward Imanuel Simon
Denta Journal Kedokteran Gigi Vol 2 No 1 (2019): Oceana Biomedicina Journal Volume 2 Issue (No) 1 January - June 2019
Publisher : Universitas Hang Tuah

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Background: Most people in Indonesia still negatively regard mental patients as someone who is dangerous and the disease cannot be cured. This happens because people do not understand well the causes and methods of care for patients with mental disorders. Negative views that exist in the community cause mental patients to get less appropriate and humane treatment in the community even in their own families, such as being installed, ignored, insulted, and alienating family members who experience mental disorders.Objectif: This study aims to determine the differences in positive or negative views of mental patients between students of the Faculty of Medicine, Hang Tuah Surabaya, 5th semester with 7th semester.Methods: The population in this study were students of the Faculty of Medicine, University of Hang Tuah Surabaya in semester 5 with semester 7. with a large sample taken as many as 136 people. The independent variables in this study were positive or negative views about mental patients while the dependent variables in this study were students of semester 5 and semester 7 students. Analysis of the data of this study using Chi Square statistical tests.Results: Obtained results of respondents from semester 5 with a positive outlook that is 38 people (55.9%) and negative views namely 30 people (44.1%), then the results of respondents from 7th semester with a positive outlook that is 53 people (77.9%) and negative view of 15 people (22.1%). Where the total number of all respondents who answered a positive view was 91 people (66.9%) and all respondents who answered negative views were 45 people (33.1%). And based on gender, male respondents who looked positively about mental patients were 51 people (66.2%) and those who viewed negativity were 26 people (33.8%). Whereas female respondents who viewed positively regarding mental patients were 40 people (67.8%) and those who viewed negatively were 19 people (32.2%).Conclusions: The results showed a significant difference regarding the differences in positive or negative views of mental patients between semester 5 students and 7th semester students, as evidenced by the acquisition of the Sig. = 0.006 (<0.05).
Pengaruh Terapi Oksigen Hiperbarik terhadap Kadar Testosteron pada Tikus Model Sindroma Ovarium Polikistik dengan Resistensi Insulin Fajar Sudiono; Lunardhi Susanto; Wachjudi Kurnia
Denta Journal Kedokteran Gigi Vol 3 No 1 (2020): Oceana Biomedicina Journal Volume 3 Issue (No) 1 January - June 2020
Publisher : Universitas Hang Tuah

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Background:Polycystic ovary syndrome (PCOS) is an endocrine disorder that has the broadest and best in women often springs reproduktif age. Factors underlying the recovery of PCOS are excessive androgens, insulin resistance, and disturbance of gonadotropin dynamics. Excessive androgen causes LH and FSH to develop. In the theory hyperbaric oxygen therapy allows to increase sensitivity tissue to insulin. The . The purpose of this research was to know effect using hyperbaric oxygen therapy 2.4 ATA 3x30 minutes for 5 sessions on testosterone levels on rats model of Polycystic Ovary Syndrome with insulin resistance.Metode:The research is experimental with post test only control group design. The total sample used as 12 rats that is divided into 2 groups. Independent variable is therapeutic oxygen hiperbarik, dependent variable testosteron level from blood sample of rats and control variables are room temperature and standard feed and control variables of androgen injection, types and specifications of experimental animals, cage size and animal care. Data analysis of this study was processed using Mann Whitney U test.Result:The results of using Mann Whitney U Test with p-value = 0,150 > α (0.05), showed no difference between testosterone levels in the experimental group given androgen injection with the group of animals given androgen injection and hyperbaric oxygen therapy.Conclusion:Therapy oxygen hyperbarik has not been effecting testosteron levels in white rats (Rattus Norvegicus) model syndroma ovarium polycystic with resistensi insulin
Ethanolic Extract Oitment of The Graptophylum Pictum L Griff Leaves as Analgesic agent to Male White Rat Setya Enti Rikomah; Ninsi Fitri
Denta Journal Kedokteran Gigi Vol 3 No 1 (2020): Oceana Biomedicina Journal Volume 3 Issue (No) 1 January - June 2020
Publisher : Universitas Hang Tuah

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Graptophyllum pictum L Griff Leaves in the community are used as medicinal ingredients, one of which is for analgesics. Black pudding leaves contain secondary metabolite compounds that act as suspected analgesics, namely flavonoids. The ethanolic extract of black pudding leaves has been formulated into cream and ointment preparations. The purpose of this study was to determine the effectiveness of analgesic preparations of black pudding leaves (Graptophyllum pictum L. Griff) ethanol extract in white male mice. The effectiveness of analgesics was tested using the hotplate method. The test animals used were 25 white male mice which were divided into 5 groups: negative control (F0), positive control (Ichtiol® ointment), and black pudding leaf F1 (10%), F2 (15%) ethanol extract treatment group, and F3 (20%). Observation of stretching of mice was done after the feet of mice were induced and immediately given treatment. Observation of analgesic percentage in each mouse was carried out every 5 minutes for 60 minutes. The data obtained were processed and analyzed using one-way ANOVA and Duncan test with a 95% confidence level. One-way ANOVA test results showed that there were significant differences between treatment groups (0.003 <0.05). The results of the average percentage of analgesic effectiveness of formula 2 have a good effect that is equal to 77.969%. Duncan's test results showed that the group that gave the best analgesic effectiveness was formula 2 (15%) comparable to positive control.
Formulasi Sabun Cuci dari Minyak Jelantah dengan Penambahan Air Asam Sunti Azmalina Adriani; Rinaldi Rinaldi; Hardiana Hardiana; Suci Suci; Irfan Mustafa
Denta Journal Kedokteran Gigi Vol 3 No 1 (2020): Oceana Biomedicina Journal Volume 3 Issue (No) 1 January - June 2020
Publisher : Universitas Hang Tuah

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Soap is a cleaning agent made from oil. Coconut oil that has been used is usually discarded as waste (minyak jelantah), with the additionof syringe acid water. Sunti acid water is one of the spices that contains quite high acidic compounds. The purpose of this study was to determine the characteristics of soaps containing Sunti acid water. This research is experimental to formulate laundry soap containing Sunti acid water, with used cooking oil. Soap formulation with Sunti acid waterconcentration 1.25% (F1), 1.50% (F2) and 1.75% (F3). The formula was evaluated with organoleptic parameters, moisture content, pH, homogeneity, high foam and clean power of soap. The results showed that soap (F1, F2, F3) was solid, brown in color and distinctively smelled of lemon, and the water content was 20.34%; 14.21% and 14.8%, pH ranges from 8-10, not homogeneous, foam height 48-78 cm and can be as a cleaner. So it can be concluded that Sunti acid water and used cooking oilcan be formulated in the form of soap and formula 3 is a good formula.

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