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Oceana Biomedicina Journal
Published by Universitas Hang Tuah
ISSN : -     EISSN : 26140519     DOI : https://doi.org/10.30649/obj
Core Subject : Health,
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health
Oceana Biomedicina Journal is an open access journal of health and medicine. Specifically, the journal focuses on marine medicine, hyperbaric medicine and health, medicine on ships, harbor health, maritime and coastal health, medicolegal studies related to ships, ports and districts, maritime/coastal communities and fishermen, epidemiological aspects of diseases, disabilities and disorders that occur on ships and affect boat workers, ports and maritime zones, coastal areas, fishermen communities and their families, including pharmacological and non-pharmacological prevention and treatment management policies; and miscellanous.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 51 Documents
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UJI EFEKTIVITAS ANTIINFLAMASI KRIM TIPE M/A DARI EKSTRAK ETANOL DAUN RANDU (Ceiba pentandra.(L) Gaertn ) PADA HEWAN UJI MENCIT PUTIH JANTAN (Mus musculus.L) Setya Enti Rikomah; Luky Dharmayanti; Melandika Dwi Sakinah
Denta Journal Kedokteran Gigi Vol 4 No 1 (2021): Oceana Biomedicina Journal Volume 4 Issue (No) 1 January - June 2021
Publisher : Universitas Hang Tuah

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Abstract

Daun Tanaman Randu (Ceiba Pentandra .(L) Gaertn) dimasyarakat digunakan sebagai obat, salah satunya untuk antiinflamasi. Daun randu mempunyai kandunganflavonoid sebagai senyawa metabolit sekunder yang diduga berperan sebagai antiinflamasi. Ekstrak etanol daun randu telah diformulasikan menjadi sediaan krim. Tujuan dari penelitian ini adalah untuk mengetahui efektifitas antiinflamasi sediaan krim ekstrak etanol daun randu pada mencit jantan putih. Efektifitas antiinflamasi diuji menggunakan metode Inflammation-associated edema. Hewan uji yang digunakan sebanyak 30 ekor mencit jantan putih yang dibagi menjadi 6 kelompok yaitu kontrol normal, kontrol negatif (F0), kontrol positif (Krim Hidrokortison), dan kelompok perlakuan krim ekstrak etanol daun randu F1 (10%), F2 (15%), dan F3 (20%). Pengamatan dan pengukuran volume tebal lipat kulit punggung mencit menggunakan jangka sorong digital dilakukan saat sebelum diinduksi dan setelah diinduksi karagenan 2%. Pengamatan penurunan volume tebal lipat kulit punggung mencit dilakuan setiap satu jam sekali selama 6 jam. Data yang didapatdiolahdandianalisa menggunakan one-way anovadanuji duncandengan tingkat kepercayaan 95%.Hasil uji one-way anova menunjukan tidak terdapat perbedaan yang nyata antar kelompok perlakuan (0,967>0,05). Hasil uji duncan menunjukan bahwa antar kelompok perlakuan memiliki efektivitas antiinflamasi yang hampir sama.
Pengaruh Pemberian Ekstrak Rumput Laut Cokelat (Sargassum duplicatum) terhadap Peningkatan Kadar Hematokrit pada Darah Tikus Putih Jantan Galur Wistar (Rattus norvegicus) Anemia yang Diinduksi NaNO2 Emy Noviana Sandy; Liliawanti Liliawanti; Wachjudi Kurnia
Denta Journal Kedokteran Gigi Vol 4 No 1 (2021): Oceana Biomedicina Journal Volume 4 Issue (No) 1 January - June 2021
Publisher : Universitas Hang Tuah

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Abstract

Background: In Indonesia, the prevalence of iron deficiency anemia reaches 25,2 percent, it indicates that anemia is a medical condition in society that needs attention. Brown seaweed (Sargassum duplicatum) is a group of algae that contains minerals such as iron and vitamin B12. So that the content in Sargassum duplicatum can be used for anemia therapy that serves as the main forming hemoglobin. Objective: The purpose of this experimental research was to determine the administration of Sargassum duplicatum affects the increase in blood haemoglobin levels of rats that are anemia induced NaNO2..Methods: This research used the Post-test only control group design, the samples were 30 male rats divided into 3 treatment groups (K0, K1, and K2). The process of treating anemia in rats using sodium nitrite (NaNO2) at a dose of 125 mg / KgBB. K0 group is a group that is not treated. K1 group is a group that was given NaNO2 for 18 days without dieting Sargassum duplicatum. The K2 group was the group that was given NaNO2 for 18 days and received the Sargassum duplicatum diet at a dose of 2.45 g/kgBB for 14 days.Result: From this research it can be seen that K0 has an average hemoglobin level of 12,71 g/dL, K1 has an average hemoglobin level of 11.96 g / dL, and K2 has an average hemoglobin level of 12,99 g/dL which shows that descriptively there is a difference between groups K1 and K2. Based on the KruskalWallis statistical test, a value of 0,290 was obtained so that p > 0.05 showed that H0 was accepted, which means there was no difference in the administration of Sargassum duplicatum in increasing blood hemoglobin levels in anemic rats.Conclusion: From the results of this research, the conclusion in descriptively there was an increase in the blood hemoglobin level of white rats in the group receiving Sargassum duplicatum extract therapy but it was not statistically significant.
UJI AKTIVITAS SENYAWA FLAVONOID DARI EKSTRAK ETANOL KULIT BUAH MANGGA (Mangifera indica L.) TERHADAP BAKTERI STAPHYLOCOCCUS AUREUS Yuska Noviyanty; Hepiyansori Hepiyansori; Tamara Dwi Insani
Denta Journal Kedokteran Gigi Vol 4 No 1 (2021): Oceana Biomedicina Journal Volume 4 Issue (No) 1 January - June 2021
Publisher : Universitas Hang Tuah

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Abstract

Salah satu bahan alam yang dapat digunakan sebgai obat yaitu kulit buah mangga (Mangifera indica L.) yang mempunyai manfaat sebagai antioksidan, antibakteri, antivirus dan antikanker. Kulit buah mangga memiliki kandungan senyawa flavonoid yang diketahui memiliki aktivitas sebagai antibakteri. Tujuan penelitian ini untuk mengetahui potensi terhadap aktivitas antibakteri dari ekstrak etanol kulit buah mangga (Mangifera indica L.)terhadap bakteri Staphylococcus aureus.Pembuatan ekstrak etanol kulit buah dilakukan dengan menggunakan metode maserasi selanjutnya dilakukan pengujian daya hambat bakteri staphylococcus aureus, dengan proses peremajaan biakan murni bakteri staphylococcus aureus dengan menggunakan metode difusi cakram, dilanjutkan dengan pembuatan media Na (Nutrient agar) dan media Nb (Nutrien broth), konsentrasi ekstrak etanol Kulit Buah Mangga (Mangifera indica L.) yang digunakan adalah 5%, 7,5%, 10%. Kontrol positif yang digunakan adalah Amoxsan capsul dan kontrol negatif menggunakan aquadest.Hasil data dianalisis dengan menggunakan metode Kruskal Wallis Test pada program SPSS 16 dengan tingkat kepercayaan 95% atau α = 0,05. Ekstrak Kulit Buah Mangga (Mangifera indica L.) mempunyai daya hambat terhadap bakteri Staphylococcus aureus. Telah di buktikan dengan adanya zona bening dan uji Kruskal Wallis Test adalah Asymp.Sig<0,05 maka ada perbedaan konsentrasi ekstrak Kulit Buah Mangga (Mangifera indica L.)
THYROTOXICOSIS IN PATIENTS WITH HYDATID MOLE Rahadianto Rahadianto; Maimun Z. Arthamin
Denta Journal Kedokteran Gigi Vol 4 No 1 (2021): Oceana Biomedicina Journal Volume 4 Issue (No) 1 January - June 2021
Publisher : Universitas Hang Tuah

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Abstract

Hydatid Mole, also often called grape pregnancy, is a pregnancy characterized by abnormal trophoblast development. The incidence of hydatidiform mole per 1,000 pregnancies occurs in Asia. In Indonesia, in 2002 cases of hydatidiform mole were found 1: 123 pregnancy, and in 2003 found cases of hydatidiform mole 1: 245 pregnancy. While the results of research conducted in the same place in 2012-2013 obtained 39 cases of hydatidiform mole that were distributed based on age groups, parity, education, and hemoglobin levels of patients. Trophoblastic hyperthyroidism is a rare case but can be life threatening. Alpha subunit-human chorionic gonadotropin (HCG) is similar to alpha sub-unit-thyroid stimulating hormone (TSH). If HCG concentrations increase over a long period of time, it can increase free T4 and free T3 levels. In this patient there was also a sudden onset of hypertension, proteinuria 3+, ketonuria 3+, hematuria 3+, leukosituria 1+, bacteriuria which could possibly be caused by the occurrence of a pre-eclampsia or UTI in this patient. The cause of pre-eclampsia in molar pregnancy is thought to be due to excessive levels of soluble fms-like tyrosine kinase 1 (sFlt1) in the circulation, an endogenous anti-angiogenic protein that enters the maternal circulation after overproduction in the placenta.
INTRACEREBRAL HEMORRHAGE (ICH) INCIDENCE PROFILE IN JEMURSARI ISLAMIC HOSPITAL DURING THE PERIOD 2017-2019 Hidayatullah Hidayatullah; Shobihatus Syifak; Choirotussanijjah Choirotussanijjah
Denta Journal Kedokteran Gigi Vol 5 No 1 (2022): Oceana Biomedicina Journal Volume 5 Issue (No) 1
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/obj.v5i1.62

Abstract

Background: Intracerebral hemorrhage or ICH or hemorrhagic stroke is caused by bleeding within brain parenchyma. Riskesdas reported that stroke patients in Indonesia experienced an increase from 7 permil in 2013 to 10.9 permil in 2018. Mortality rate for ICH is estimated 40% in 1 month and 54% in 1 year. Rumah sakit Islam Jemursari (RSI) is the only type B hospital in Wonocolo sub-district, Surabaya city. This study aimed to analyze the pattern of incidents and variations of ICH at RSI Jemursari Surabaya.Method: This was a descriptive observational study. Medical record data is collected from 2017-2019. The data were obtained from medical records section of total number of ICH, gender, age and outcome of patients. Furthermore, data is analyzed and illustrated through a bar chart and the frequency of mortality is calculated.Results: Total ICH patients at Jemursari Hospital were 310 with 192 male patients and 118 female patients over 3 years. Meanwhile, the most groups experienced ICH were 45-64 years, followed by +65 age group. This is consistent with several epidemiological studies related to ICH, where the incidence of ICH increases with increasing age. The mortality rate for ICH patients, in the 2017-2019 periode, was around 23-30%.Conclusion: It can be concluded that male more susceptible to ICH than female subjects. Meanwhile, the mortality rate for ICH patients ranged from 23-30% in the 2017-2019 period. It is necessary to carry out further evaluation related to other data from the patient. So it could describe incidence rate as well as an overview of the ICH profile at RSI Jemursari.
EFEKTIVITAS ANALGETIK KRIM TIPE M/A EKSTRAK ETANOL DAUN RANDU (Ceibapentandra (L) Gaertn) PADA HEWAN UJI MENCIT JANTAN Setya Enti Rikomah; Devi Novia; Muhammad Fadhly
Denta Journal Kedokteran Gigi Vol 5 No 1 (2022): Oceana Biomedicina Journal Volume 5 Issue (No) 1
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/obj.v5i1.63

Abstract

Randu plant leaves (Ceiba pentandra (L) Gaertn) are commonly used in traditional medicine, one of which is an analgesic with secondary metabolites which are thought to be analgesics, namely flavonoids. The purpose of this study was to determine the analgesic effectiveness of the ethanol extract cream of randu leaves (Ceiba pentandra (L) Gaertn) in white male mice (Mus musculus). The research on the analgesic effectiveness of the ethanol extract cream of randum leaves used the hot plate method and used male white mice as the experimental animal media. The soles of the hind legs of the mice were heated over hot plated with a temperature of 550C then the test animals were given the treatment which was divided into 5 treatment groups, namely positive control (Conterpain cream), negative control (F0), F1 (10%), F2 (15%), F3 (20%) and 1 normal group. The response of mice was calculated every 30 minutes in 120 minutes. The data obtained were analyzed using the one-way ANOVA statistical test followed by the Duncan test with a confidence level of 99%. The results of the one-way ANOVA test showed that there were significant differences between treatment groups (0.00 <0.05). The results of the Duncan test showed that the group that provided the best analgesic effectiveness was F2 (15%) but not better than Positive Control.
UJI STANDAR MUTU SIFAT FISIK SABUN PADAT TRANSPARAN MINYAK SEREH WANGI (Cymbopogon nardus L.) DARI VCO (Virgin Coconut Oil) Betna Dewi; Gina Lestari
Denta Journal Kedokteran Gigi Vol 5 No 1 (2022): Oceana Biomedicina Journal Volume 5 Issue (No) 1
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/obj.v5i1.64

Abstract

Sabun merupakan sediaan yang paling banyak digunakan yang bersifat sebagai pembersih dan anti bakteri bagi tubuh. Penggunaan VCO sebagai basis sabun padat transparan karena VCO karena kandungan asam lemak yang  menguntungkan  kulit Proses pembuatan sabun dengan metode panas, dengan basis VCO yang dibuat metode penggaraman. Evalusi standar mutu meliputi uji organoleptis, uji tinggi busa dan stabilitas busa Hasil uji standar mutu sifat fisik yaitu uji organoleptik, uji tinggi busa dan stabilitas busa memenuhi standar mutu sediaan sabun yang beredar dipasaran, tidak terjadi perbedaan mutu fisik yang bermakna antara sabun padat transparan minyak sereh wangi yang diformulasi dengan sabun padat transparan yang beredar.
VARIASI KOSENTRASI EKSTRAK ETANOL KULIT BUAH MANGGA HARUM MANIS (Mangifera indica L var. arum manis) TERHADAP FORMULA SEDIAAN GEL HAND SANITIZER SEBAGAI ANTIBAKTERI Yuska Noviyanty; Hepiyansori Hepiyansori; Annis Annis
Denta Journal Kedokteran Gigi Vol 5 No 1 (2022): Oceana Biomedicina Journal Volume 5 Issue (No) 1
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/obj.v5i1.66

Abstract

One of the medicinal plants that can be used as a source of natural medicine is mango (Mangifera indica L.) because it contains secondary metabolite compounds, mango plants contain many benefits both at the root, skin, leaves, fruits and seeds. Mango skin contains important active compounds such as phenolic compounds, carotenoids, flavonoids and anthocyanins. Sweet Arum mango skin has antibacterial activity. The extraction method used is maceration with 96% ethanol solvent. The formulation was prepared using Na.CMC as a gelling agent with a concentration of 2%, 4%, 8%. The evaluation test of mango skin extract hand sanitazer preparation includes organoleptic test, homogeneity test, pH test, spreadability test, sticking test, irritation test and antibacterial test. The results showed that the physical properties of the gel preparations had an influence on the physical properties of the mango skin extract gel (Mangifera indica L). Based on the antibacterial activity test the concentration of 2%, 4%, 8% which most strongly shows the antibacterial activity at a concentration of 8% with an average value of 18.28 mm.
HUBUNGAN KETEPATAN TERMINOLOGI MEDIS DENGAN KEAKURATAN PENGODEAN BERDASARKAN ICD-10 DI RUMAH SAKIT SECARA STUDY LITERATURE REVIEW Deni Maisa Putra; Yulfa Yulia; Rahmadhani Rahmadhani; Athiyah Holindra
Denta Journal Kedokteran Gigi Vol 5 No 1 (2022): Oceana Biomedicina Journal Volume 5 Issue (No) 1
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/obj.v5i1.67

Abstract

Background: Accurate coding using appropriate diagnosis writing with appropriate medical terminology. And help the coding officer to code the disease according to ICD-10. This study aims to determine the relationship between medical terminology and the accuracy of coding based on ICD-10 in hospitals. Methods: The method used is a literature study carried out by describing the facts that exist and then being analyzed. Searching for articles through Google Scholar, with inclusion and exclusion criteria, the final results obtained 5 analyzed journals. Furthermore, the analysis is carried out by looking at the compare, contrast, critize, synthesize, summarize. Result: The results of this literature review show that from the 5 journals that have been analyzed there are 3 journals that have medical terminology accuracy with a percentage of more than 50%, 4 journals that have coding accuracy with a percentage of more than 50%, and 4 journals that have a relationship between terminology accuracy. Medical with coding accuracy. Conclusion: Based on the results of the literature review, it can be concluded that there is a need for uniformity and consistency in the use of medical terminology according to ICD-10 to further improve the accuracy of the code. So there should be communication between the coder and the doctor so that the perception between the two is the same and produces an accurate code.
HUBUNGAN TINGKAT PENGETAHUAN TENTANG KANKER PAYUDARA TERHADAP PERILAKU SADARI PADA MAHASISWA FK UMSU ANGKATAN 2019 Heppy Jelita Batubara
Denta Journal Kedokteran Gigi Vol 5 No 1 (2022): Oceana Biomedicina Journal Volume 5 Issue (No) 1
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/obj.v5i1.68

Abstract

Referring to the problem of breast cancer, it is necessary to do early detection of breast cancer. Efforts to control breast cancer have been carried out by the Government of Indonesia specifically through an early detection program for cancer in Indonesian women for breast cancer along with an early detection program for cervical cancer. Early detection of breast cancer is an effort to detect and identify breast cancer early or not, so it is hoped that it can be treated with techniques that have little physical impact and have a greater chance of recovery. Cancer is one of the non-communicable diseases that is a public health problem in Indonesia and in the world. The death rate in the world is caused by cancer and is the second killer after cardiovascular disease, namely 12%. Breast cancer is a malignancy in breast tissue that can originate from the ductal epithelium or its lobules. Breast cancer is one of the most common types of cancer in Indonesia. Breast cancer ranks second after cervical cancer which attacks women worldwide. According to GLOBOCAN 2012 the highest incidence of breast cancer in ASEAN is owned by Indonesia at 48,998 and 40.3 per 100,000 women (AISR Age Standardize Incidence Rate), followed by the Philippines at 18,327 (47), Thailand at 13,653 (293) and Malaysia at 5,410 (38.7) The number of cases of breast cancer patients in North Sumatra was 2,682 per 100,000 with a diagnosis prevalence of 0.4%. The data obtained from the study had 98 samples of research respondents who met the inclusion criteria, the results of the study were obtained regarding "The relationship between the level of knowledge about breast cancer and BSE behavior in FK UMSU students Batch 2020 is sufficient. This is indicated by the results of the presentation of a high level of knowledge 48, 45%, moderate as much as 41.24% and low as much as 10.31% The level of knowledge of each student is different.

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