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Zahratul Aini
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dr.zahratulaini@unsyiah.ac.id
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INDONESIA
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia
Published by Universitas Islam Indonesia
ISSN : 20854145     EISSN : 25272950     DOI : 10.208885/JKKI.Vol10.Iss3.art5
Core Subject : Health,
Medicine & Pharmacology Public Health
JKKI: Jurnal Kedokteran dan Kesehatan Indonesia is a peer-reviewed journal in the field of medical and health sciences. This journal is designed as a place of dissemination of information and scientific knowledge, which publishes three times a year. It publishes original article, article review, and case report. These comprise of biomedical sciences, clinical medicine, public health sciences, and medical science education.
Arjuna Subject : Kedokteran - Kedokteran Keluarga
Articles 468 Documents
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Late latent syphilis with early syphilis titer in pregnancy: A case report Frieda Yanuar; Eka Devinta Novi Diana; Wibisono Nugraha; Ammarilis Murastami; Endra Yustin Ellistasari
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 13, No 1, (2022)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol13.Iss1.art14

Abstract

Syphilis is a chronic and systemic sexually transmitted infection caused by Treponema pallidum. The prevalence of syphilis according to the World Health Organization (WHO) is around 12 million cases worldwide and in pregnant women around 1.8 million cases. Syphilis screening in pregnancy is important to break the chain of transmission of congenital syphilis. We reported Mrs. S, 33 years old, 18 weeks pregnant, came with history of itchy patches appeared 8 months ago along with her husband and abortion 1 year ago. The plantar pedis dextra et sinistra showed multiple hyperpigmented macules and no clinical founding in the vagina. Serological tests, reactive Venereal Disease Research Laboratory (VDRL) 1:32, Treponema pallidum hemagglutination (TPHA) >1:5120 and non-reactive human immunodeficiency virus (HIV), support the diagnosis of latent syphilis. Patients were injected with benzathine penicillin 2.4 million units 3 times (1 week apart). Serological test evaluated at months 1, 3 and 6. At month 6, there was a decrease in VDRL value 4 times the initial value, indicating successful therapy in laten syphilis and had received therapy according to the guidelines for late latent syphilis. Syphilis in pregnancy can cause congenital syphilis in the fetus, although latent syphilis has no symptoms. The patient's VDRL titer was reactive in early latent syphilis (>1:8), but based on history and duration of infection more than 1 year including late latent syphilis. Based on this case report, we found that the VDRL titer value did not always correspond to the duration of infection.
Protective effect of ethanolic extract of white oyster mushroom on morphological rat sperm damage due to cigarette smoke exposure Santun Bhekti Rahimah; Rio Dananjaya; Ermina Widyastuti; Yudi Feriandi
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 12, No 3, (2021)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol12.Iss3.art10

Abstract

Background: Cigarettes smokes are a great external source of free radicals. The negative effects of cigarette smoke exposure can be systemic and affect all body systems, including the reproductive. Male rats exposed to cigarette smoke have a risk of oxidative stress and sperm damage. This can be overcome with herbal antioxidants such as white oyster mushrooms (Pleurotus ostreatus).Objective: This study aimed to examine the protective effect of ethanolic extract of white oyster mushroom against damage to sperm morphology of rats exposed to cigarette smoke.Methods: This study is an experimental study using 40 rats which were divided into 5 groups. Group I (normal control), group II (negative control) were only given exposure of cigarette smoke, Grups III, IV and V (treatments groups 1, 2, and 3) were given exposure of cigarette smoke and ethanolic extract a dose of 125, 250, and 500 mg/Kg BW/day for 14 days. On the 15th day, the percentage normal rat sperm were calculated under a 400x magnification microscope.Results: Normal sperm count in group I was 79% ± 0.79, group II was 39% ± 0.55, Grup III, IV and V were 56% ± 0.15, 65% ± 0.54 and 66% ± 0.21.  
Antidiabetic potential of karamunting leaves ethanolic extract as a natural herb: Blood glucose levels and pancreatic islets histomorphology on diabetic rats model Ida Yuliana; Asnawati Asnawati; Maria Ulfah; Eko Suhartono
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 12, No 3, (2021)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol12.Iss3.art9

Abstract

Background: Karamunting leaf is a wetland herb with antioxidant compounds that bind free radicals, reduce oxidative stress, reduce insulin resistance, and prevent the development of pancreatic cell dysfunction and damage.Objective: This study aims to prove the antidiabetic potential of the karamunting leaves ethanolic extract in treating diabetes in white male rats.Methods: This study used a true experimental with a pre-test and post-test control group design. Thirty rats were divided into four groups (control: C, ethanol extract of karamunting dose of 100 mg: P1, 200 mg: P2, and 400 mg: P3). Data on fasting blood glucose levels were taken before (pre-test) and after treatment (post-test). Data on pancreatic islets histomorphological changes (size, number, constituent cells) were analysed quantitatively. Fasting blood glucose levels were analysed using paired t-test, while the histomorphological data of the pancreatic islets were analysed using ANOVA. The data were considered significant if the p-value <0.05 (95% CI).Results: Karamunting leaf ethanol extract treatment reduced fasting blood glucose levels in diabetic rats. A 200 mg/kgBW was demonstrated as the most effective dose that improves the islets and cells number compiles the pancreatic islets, potentially treating diabetes mellitus (DM).Conclusion: Karamunting leaf ethanol extract potential as a natural herbal medicine in treating DM.
Antibacterial activity of extract sangkareho leaves (Callicarpa longifolia LAM.) on Salmonella typhi and Staphylococcus epidermidis Silvani Permatasari; Ervi Audina Munthe; Muntir Guru Singa; Elsa Trinovita; Ratna Widayati; Natalia Sri Martani; Anna Marthea Veronica
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 13, No 1, (2022)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol13.Iss1.art7

Abstract

Background: The most commonly found disease-causing microorganisms are the Salmonella typhi and Staphylococcus epidermidis bacteria. S.typhi is a gram-negative bacterium that causes typhoid fever, and S.epidermidis is a gram-positive bacterium that attacks mucous membranes and human skin. Sangkareho (Callicarpa longifolia Lam.) is one of the indigenous herbal plants of Central Kalimantan, which is empirically used as a wound medicine, diarrhea, diabetic, anti-inflammatory, and can be an antibacterial agent.Objective: This study used six groups are concentrations of 10%, 25%, 50%, and 100%, Chloramphenicol as a positive control, and dimethyl sulfoxide (DMSO) as a negative control. Methods: The method used for this test is the well diffusion method. In Nutrient Agar (NA) media, holes were made to insert 40 μl of each extract concentration, positive and negative control with four repetitions, then incubated for 18-24 hours at 37ºC. Data analysis using the One Way Anova test.Results: The research findings showed that ethanol extract of sangkareho leaves with all concentrations had an inhibitory effect against both bacteria tested.Conclusion: The ethanol extract of sangkareho leaves at the concentration of 10% was found to be the optimum and at the concentration of 100% was the maximum effectiveness for inhibiting S. typhi and S. epidermidis.
Threat of obesity behind COVID-19 Nur Aini
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 12, No 2, (2021)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol12.Iss2.art2

Abstract

No abstract
Stem cells and gene therapy in epilepsy management Dito Anurogo
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 12, No 2, (2021)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol12.Iss2.art1

Abstract

No abstract
Family history of PCOS, obesity, low fiber diet, and low physical activity increase the risk of PCOS Alfaina Wahyuni; Supriyatiningsih; Wiwik Kusumawati; Kamila Sedah Kirana; Cynthia Dwi Mayayustika
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 13, No 1, (2022)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol13.Iss1.art8

Abstract

Background: Polycystic ovarian syndrome (PCOS) is a common endocrine disorder and leading cause of prolonged anovulation. PCOS has been linked to a variety of long-term health problems, including: heart disease; metabolic syndrome; and diabetes. It is interesting to know the risk factors for PCOS in local settings.Objective: The aim of this research is to identify PCOS risk factors in our own settings (Asri Medical Center in Yogyakarta), so that we could identify the specific preparation to avoid having disorders personalized in localcharacteristics.Methods: This is a descriptive-analytic cross-sectional study. The research was carried out at Asri Medical Center in Yogyakarta, Indonesia, with a total sample size of 92 people who met the inclusion and exclusion criteria. They were divided into two groups: non-PCOS and PCOS. Data were retrieved using the questionnaire. The variables evaluated were nutritional status, physical activity, carbohydrate diet, fiber diet, family history of diabetes, family history of PCOS, and age of menarche. The data was analyzed usingthe Chi-square test.Results: Family history of PCOS, obesity, low physical activity and a lowfiber diet proved to differ significantly between the two groups (p<0.05).Conclusion: Family history of PCOS, obesity, low physical activity, low fiber diet had a substantial impact on the occurrence of PCOS.
Rehabilitation management of pediatric post-Covid 19 syndrome: A case report Rizky Kusuma Wardhani; Luh Karunia Wahyuni; Budiati Laksmitasari; Clements Clements; Skolastika Mitzy Benedicta
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 13, No 1, (2022)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol13.Iss1.art13

Abstract

Indonesia is one of the countries with highest rate of COVID infection in pediatric population. Although the symptoms of acute COVID infection in children are mostly mild, several studies report frequent post-COVID persisting symptoms in pediatric population, causing limitations in daily activities. This case report discusses rehabilitation therapy in a 12 years old child diagnosed with post-COVID syndrome. Rehabilitation therapy in the form of breathing exercise, muscle strengthening, and aerobics exercise can improve subjective complaints, cardiopulmonary endurance, and quality of life at two weeks follow-up. Further research is needed to determine the correlation between rehabilitation therapy and the outcome of children with post-COVID 19 syndrome.
Risk factors for carpal tunnel syndrome in pregnant women Lia Dwi Prafitri; Wahyu Ersila; Dzikra Nurseptiani
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 13, No 1, (2022)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol13.Iss1.art9

Abstract

Background: Carpal Tunnel Syndrome (CTS) affects 267 people out of every 100,000 in the United States each year, with a prevalence of 9.2% in women and 6% in men. Women are three times as vulnerable as men. Pregnancy can be a risk factor for CTS, which typically occurs in the first and third trimesters and is bilateral. Signs and symptoms will be persistent if CTS develops in early pregnancy and may recur in subsequent pregnancies. Hormonal changes during pregnancy can put you at a greater risk of developing CTS symptoms because the structure of the wrist enlarges and can put pressure on the nerves in the wristObjective: This research aims to identify risk factors for the occurrence of CTS in pregnant women. Early detection of risk factors for CTS needs to be done early in pregnancy to be able to make appropriate prevention and treatment efforts for pregnant women who experience CTS.Methods: TThis research employed an observational method in conjunction with quantitative analytical research. The population of this research included all pregnant women in the working area of Kedungwuni Health Center I and II in Pekalongan Regency. The sampling technique used was cluster random sampling, with 108 pregnant women meeting the inclusion criteria. Data collection methods entailed interviews and documentation using questionnaires, Phalen's test sheets, and nutritionalstatus measuring tools such as the microtome and bathroom scale. The risk factors to be studied are the relationship between employment status, parity, the incidence of CED, nutritional status before pregnancy, and a history of the disease, with the incidence of CTS. Chi-Square and Odds Ratio was used in bivariate analysis, while multivariate analysis used logistic regression.scar. Significance was set at p<0.05.Results: The incidence of CTS is significantly related to employment status, nutritional status before pregnancy, CED incidence, parity, and previous medical history (p-value < 0.05).Conclusion: Starting from the strongest, the strength of the relationship shown by the OR results is employment status (OR 7,231), medical history (OR 6,214), and the incidence of CED (OR 3,428). Occupational status has the highest odds ratio, making it the most important factor in the occurrence of CTS in pregnant women in the Pekalongan Regency
Internet-based physical activity promotion in the post pandemic era Muhammad Ikhwan Zein
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 12, No 3, (2021)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol12.Iss3.art1

Abstract

No abstract

Page 31 of 47 | Total Record : 468

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