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Media Farmasi Indonesia
Published by Sekolah Tinggi Ilmu Farmasi Yayasan Pharmasi Semarang
ISSN : 19788495     EISSN : 26551462     DOI : https://doi.org/10.53359/mfi.v17i1
Core Subject : Health, Science, Education,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Other
Media Farmasi Indonesia publishes original article in the all scopes of Pharmaceutical Science such as Pharmaceutics, Biopharmaceutics, Drug Delivery System, Chemical Pharmacy, Pharmaceutical Technology, Pharmaceutical Microbiology and Biotechnology, Pharmacology and Toxicology, Pharmacokinetics, Pharmaceutical Chemistry, Pharmaceutical Biology, Community and Clinical Pharmacy, Management Pharmacy, Alternative Medicines.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 197 Documents
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Evaluation Of The Use Of Prophylaxic Antibiotic Drugs In Hernia Surgery Patients In Madiun City Hospital Mastur, Afif; Cahyaningrum, Yanuar As´hari Cahyaningrum; Zainal Abidin
Media Farmasi Indonesia Vol. 20 No. 1 (2025): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/mfi.v20i1.301

Abstract

Hernia menempati urutan ke 14 sebagai penyakit paling banyak menyumbang pasien rawat jalan dan rawat inap. Berdasarkan Kemenkes tahun 2021 hernia menjadi penyakit berjumlah 20.400 pasien, di tahun 2018 sepuluh penyakit rawat inap terbanyak hernia menduduki peringkat ke 8 dengan jumlah pasien 286 dengan angka 2.45% dari total jumlah pasien rawat inap, sehingga perlu dilakukanya evaluasi pengobatan pada peyakit hernia terutama pada pemilihan dan pemberian obat saat pembedahan seperti penggunaan antibiotik profilaksis. Penelitian ini bertujuan untuk mengevaluasi penggunaan antibiotik profilaksis pada pasien bedah hernia di RSUD Kota Madiun, menggunakan pendekatan crosssectional dan pengambilan data dilakukan secara retrospektif. Data yang di ambil meliputi data rekam medis pasien dengan kriteria pasien dengan diagnosa penyakit hernia, pasien yang mendapat tindakan operasi bedah, pasien dengan usia diatas 18 tahun atau pasien dewasa, dan pasien dengan data rekam medis yang lengkap meliputi data pengobatan dan data umum pasien.hasilpenelitian menggambarkan daritotalpasien yang terkena hernia 93% diantaranya didominasi oleh pasien laki-laki daripada wanita yang hanya 7%, usia paling banyak terkena hernia adalahpasiendenganusia65tahunkeatasberjumlah58%(58pasien).Hasilpenelitian pada bedah herniadengan nilai DDD (Defined Daily Dose)tertinggidan menjadi antibiotik yang paling banyak digunakanadalah Cefazolin dengan total 17,05 DDD/100 hari rawat sebagai antibiotik yang paling sering diberikan dari 100 pasien rawat inap dimana 72 diantaranya menggunakan cefazolin.
Hedonic Test Of Lipstick Combination Of Red Dragon Fruit Peel Extract (Hylocereus Polyrhizus) And Beetroot Tuber Extract (Beta Vulgaris L.) As Natural Colorant Fauzia, Rizki Rahmah; Karsidin, Bambang; Tristianti, Deswita
Media Farmasi Indonesia Vol. 20 No. 1 (2025): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/mfi.v20i1.303

Abstract

Not all waste from natural materials produced can be utilized properly by humans to produce higher economic value. The waste in question is red dragon fruit skin which contains anthocyanin pigments and betasianin pigments. Pigments can be used as colorants in lipstick but the intensity of the resulting color is less attractive. This study aims to determine the lipstick combination of Red Dragon fruit peel extract (Hylocereus polyrhizus) and Beet tuber extract (Beta vulgaris L.) most preferred by panelists as a natural colorant. The method used in this study was experimental. Preparation of Red Dragon fruit peel extract and Beetroot tuber extract using maceration method with 70% ethanol solvent. Then the extract was made into 3 lipstick preparation formulas at a concentration of 30% with a ratio of 1: 2 (X1), 1,5 : 1.5 (X2) and 2: 1 (X3). Hedonic tests include texture, color, aroma and appearance of lipstick preparations using a Likert scale. The combination lipstick produces color and percentage of liking, namely purple and preferred by 43.75% (X1), pink with 51.25% hedonic percentage (X2), and the most preferred by 58.75% (X3) with a dark red color, while the negative control has a yellow color with the smallest liking value of 28.75%.
Antioxidant Test Of Granola Bar Functional Food With Cork Fish And Beetroot (Beta Vulgaris L) As Supplementary Food To Prevent Stunting Pradana, Riska; Septiana Laksmi Ramayani
Media Farmasi Indonesia Vol. 20 No. 1 (2025): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/mfi.v20i1.307

Abstract

Stunting generally occurs in children who have not received nutritious food intake. Sources of nutrition are not only sourced from animal protein but can also be sourced from plants. Combining high-protein foods from animal and vegetable sources will reduce stunting rates in growing children. Snack bars are a beneficial food product that provides all the essential nutrients for the body. In addition, probar consumption in Indonesia is still relatively low, and some people don’t even know it exists. These snacks are high in usable energy and contain essential nutrients. This study aims to determine the free radical-catching activity of Granola Bar Functional Food with Cork Fish and Beetroot Fruit as Supplementary Food to Prevent Stunting. Free radical scavenging activity test was conducted using the DPPH (1,1- diphenyl- 2-picrylhydrazyl) method using quercetin as the comparative compound. Antioxidant activity analysis was performed using a spectrophotometer at a wavelength of 512 nm.
Optimization Formula Of Kolang-Kaling (Arenga Pinnata.) Peel-Off Gel Mask With Combination Pva - Cmc Na As Gelling Agent On Simplex Lattice Design Martha Cahyani, Intan; Hanhadyanaputri, Eka Susanti; Wulan , Ariani Hesti; Sulistyarini, Indah
Media Farmasi Indonesia Vol. 20 No. 1 (2025): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/mfi.v20i1.316

Abstract

Kolang-kaling fruit in topical preparations increase its effectiveness as an antioxidant. The peel-off gel mask is as an effective topical preparation for skin health and user comfort. Its formulation is determined by quality parameters, particularly forming a plastic film of PVA and CMC Na as polymers. This study aims to determine the effect of these combination and the ratio of both concentrations based on the physical characteristics and IC50 value. The optimization on the simplex lattice design was obtained in 8 runs with PVA concentrations (10% -15%) and CMC Na (0.5% -5.5%). The pH value, spreadability, adhesion, drying time, and IC50 were used as parameters to determine optimal formula. The results showed that the difference in PVA and CMC Na concentrations had a significant effect on all optimization parameters (p-value <0.05) and the lack of fit for each replication was not significant (p-value> 0.05). The optimal formula obtained PVA concentration of 14.97% and CMC Na 0.53% with a predicted pH of 5.55; adhesion of 6.63 seconds; spread power of 20.34 cm; drying time of 18 minutes, and IC50 of 25.5 ppm (desirability of 0.954), which is not significantly different from the observation results indicating the optimization is valid.
Determination Of The Difference Handrub Boiled Betel Leaf (Piper Betle) Compared Alcohol On The Percentage Of Reducing The Number Of Microorganism Colony pramesti, kadesha
Media Farmasi Indonesia Vol. 20 No. 1 (2025): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/mfi.v20i1.317

Abstract

tel leaf (Piper Betle Linn) is one of the natural ingredients that can be used as a substitute for alcohol in hand sanitizers. This study aims to analyze the differences in handrubs from boiled betel leaves (Piper betle) compared to 70% alcohol on the percentage of reduction in the number of microorganism colonies. The type of research conducted was experimental research with a Pre Post Test Group Design research design. Sampling was carried out by Concutive Sampling from Students of the Faculty of Medicine, Sultan Agung Islamic University, Semarang through the glove juice method with a total of 20 samples per group. Data on the percentage of reduction in the number of microorganism colonies between the handrub group boiled betel leaves (Piper betle) compared to 70% alcohol were analyzed using Mann Whitney. The results of the study found that 70% alcohol handrub was better than handrub boiled betel leaves (Piper betle Linn) with a difference in handrub boiled betel leaves of 39.46% and handrub 70% alcohol of 59.18%. So it is concluded that there is a significant difference between handrub boiled betel leaves (Piper betle) compared to 70% alcohol.
Development and Validation of a Questionnaire on Knowledge, Attitudes, and Practices Regarding the Use of Natural Medicine in Diabetes Mellitus: Development and Validation of a Questionnaire on Knowledge, Attitudes, and Practices Regarding the Use of Natural Medicine in Diabetes Mellitus sasongko, santi setiani
Media Farmasi Indonesia Vol. 20 No. 1 (2025): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/mfi.v20i1.318

Abstract

The use of natural ingredient drugs as complementary therapy for diabetes mellitus (DM) is increasing, both globally and in Indonesia. DM patients often seek alternatives or complements to conventional treatment with the hope of managing blood sugar levels, reducing medication side effects, or improving quality of life. Therefore, it is important to have a valid and reliable measurement tool to identify the level of knowledge, attitudes, and actions of patients regarding herbal medicine. This study aims to develop and validate a questionnaire that measures patients' knowledge, attitudes, and actions regarding the use of natural substance drugs in Diabetes Mellitus (DM). The development of the questionnaire was carried out through several stages: (1) Identification of concepts based on literature and previous research, (2) Development of questionnaire items, (3) Content validation by two experts (expert judgment), (4) Language comprehension test on five respondents, and (5) Validity and reliability test on 30 DM patients. The resulting questionnaire consists of three sections: knowledge (10 items), attitude (12 items), and actions (7 items). The results of the developed questionnaire proved to be valid and reliable for evaluating patients' understanding of herbal medicine in diabetes mellitus. Keywords: Natural ingredient medicine, diabetes mellitus, instrument validation.
Inhibition Of Α-Amylase Enzyme With Extract And Fraction Of Zingiber Zerumbet Rhizome suskawati, ida suskawati; Endang dwi wulansari; Athika Darumas Putri
Media Farmasi Indonesia Vol. 20 No. 1 (2025): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/mfi.v20i1.322

Abstract

Abstract Diabetes mellitus merupakan salah satu penyakit tidak menular yang banyak menyerang masyarakat saat ini. Penyakit ini ditandai dengan kadar glukosa darah yang lebih tinggi dari biasanya. Inhibitor α-amilase memperlambat tahap akhir pencernaan karbohidrat dan mencegah glukosa memasuki aliran darah. Inhibitor α-amilase herbal alami menjadi semakin penting dalam pengobatan diabetes karena kemanjurannya dengan efek samping yang lebih sedikit Zingiber zerumbet merupakan salah satu jenis zingiber yang sering digunakan. Inhibisi α-amilase dilakukan untuk mengetahui aktivitas penghambatan ekstrak dan fraksi rimpang lempuyang terhadap enzim α-amilase. Pengujian ini dilakukan dengan menggunakan metode DNS. Ekstrak rimpang lempuyang mengandung alkaloid, flavonoid, fenolik, tannin, dan terpenoid. Fraksi heksan hanya mengandung terpenoid. Fraksi etil asetat mengandung senyawa flavonoid dan triterpenoid. Fraksi butanol mengandung alkaloid, fenolik, tanin dan flavonoid sedangkan fraksi air mengandung fenolik dan alkaloid. Hasil penelitian diperoleh %inhibisi pada ekstrak, fraksi heksan, fraksi etil asetat, fraksi butanol dan fraksi air masing-masing sebesar 72,15%; 81,96%; 86,47%; 77,81%, dan 80,52%.
Nurses' knowledge and management of incompatibility issues in intravenous pharmaceutical preparations Rahmawati, Fita; Erna Prasetya Ningrum; Marlyn Dian Laksitorini; Endang Lukitaningsih
Media Farmasi Indonesia Vol. 20 No. 2 (2025): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/mfi.v20i2.312

Abstract

Administering multiple intravenous (IV) preparations through a single catheter line can lead to incompatibility issues, such as precipitation. Precipitation can be avoided with sufficient knowledge by nurses during the administration of IV preparations to patients. This research aims to assess nurses' knowledge and management of incompatibility issues in IV pharmaceutical preparations. This non-experimental research collected data through interviews with healthcare professionals (nurses). The research was conducted at Sultan Agung Islamic Hospital, Semarang. A total of 14 healthcare professionals (nurses) who reconstituted and administered IV pharmaceutical preparations to patients in the Intensive Care Unit (ICU) participated in the research. The results revealed that 13 nurses (92.9%) encountered incompatibility incidents with seven types of drugs. Five nurses (29.4%) reported incompatibility issues with cefoperazone. The most frequently observed incompatibility was color change, reported by seven nurses (53.8%), such as white spots appearing during phenytoin reconstitution and discoloration in IV pharmaceutical preparations of cefoperazone and ceftriaxone. The most common approach to addressing incompatibility was replacing the preparation, reported by six nurses (46.2%). The management of incompatibility issues varied among nurses, even when dealing with the same pharmaceutical preparation. Therefore, training on sterile preparation incompatibility should be provided to all healthcare professionals to establish a standardized operational procedure (SOP) for handling incompatibility in IV pharmaceutical preparations.
Design of a Web-Based Pain Module for a Medication Record Application to Support Pharmacist Self-Medication Services: Design of a Web-Based Pain Module for a Medication Record Application to Support Pharmacist Self-Medication Services Baharun, Suraya; Dimas Adhi Pradana; Sri Haryanti
Media Farmasi Indonesia Vol. 20 No. 2 (2025): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/mfi.v20i2.326

Abstract

Today's pharmacists' roles in healthcare services are changing quickly, and the key to staying up to date is internet-based drug records. Pharmacists have a significant impact on the field of health technology, particularly when it comes to patient medication records through the use of certain technologies. As professionals, pharmacists must play a bigger part in using digital technology to help improve patient safety and public health (patient safety). Medication records are one of the documents from pharmaceutical services carried out by pharmacists in pharmacies. Web-based pharmacist medication records can be used to document the provision of over-the-counter medications, referred to as self-medication services. This study aims to determine the usability of the web-based pharmacist medication record application developed as a supporting tool for community pharmacists in self-medication services. The research method used is Research and Development (R&D). The initial stage of the research involved interviews with 10 pharmacists to identify the needs of the application. Based on the interview results, self-medication for pain is the most common case occurring in pharmacies, so the researchers added a pain module to this application. Usability testing was conducted using the USE questionnaire to 135 respondents (45 pharmacists and 90 patients) in the city of Semarang. The test results show that the application meets usability criteria with the categories of usefulness, easy of use, easy learning, and satisfaction.
Development Of Pharmacist Counseling Application Android-Based For Hypertension Patients Putri Maharani; Sri Haryanti; Kyky Herlyanti
Media Farmasi Indonesia Vol. 20 No. 2 (2025): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/mfi.v20i2.332

Abstract

In Indonesia the use of telepharmacy in clinical services is still not widely utilized. The counseling activities conducted by community pharmacists have not yet been optimal, and the documentation related to clinical pharmacy services is still considered very poor. This research aims to determine the usability of the Android-based pharmacist counseling application developed for hypertensive patients. The usability of the application includes the criteria of usefulness, ease of use, ease of learning, and user satisfaction. The method used in this research is Research and Development with the 4D model (define, design, develop, and disseminate). The sample in this study consists of 45 pharmacists practicing in pharmacies in Semarang City and 100 patients aged 18-40 years residing in Semarang City. The sampling technique in this study used purposive sampling. Usability testing used the USE questionnaire via Google Forms with assessment using a Likert scale. The collected data were analyzed using usability percentages. The research results show that the developed Android-based pharmacist counseling application for hypertensive patients meets usability criteria with a usefulness score of 87.66%, ease of use score of 91.40%, ease of learning score of 93.48%, and user satisfaction score of 87.92%.

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