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Jurnal Riset Rumpun Ilmu Kedokteran (JURRIKE)
Published by Pusat Riset dan Inovasi Nasional
ISSN : 2828934X     EISSN : 28289358     DOI : https://doi.org/10.55606/jurrike.v1i2
Core Subject : Health,
Health Professions Medicine & Pharmacology Nursing Public Health Veterinary
Jurnal Riset Rumpun Ilmu Kedokteran adalah jurnal yang ditujukan untuk publikasi artikel ilmiah yang diterbitkan oleh Pusat riset dan Inovasi Nasional, Universitas Sains dan Teknologi Komputer. Jurnal ini adalah jurnal Riset Rumpun Ilmu Kedokteran yang bersifat peer-review dan terbuka. Bidang kajian dalam jurnal ini termasuk sub rumpun Ilmu Kedokteran Spesialis, Ilmu Kedokteran Akademik, Spesialis Kedokteran gigi dan mulut, Kedokteran Gigi Akademik. Jurnal Riset Rumpun Ilmu Kedokteran menerima artikel dalam bahasa Inggris dan bahasa Indonesia dan diterbitkan 2 kali setahun: April dan Oktober.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 235 Documents
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Efektivitas Latihan Lying Leg Curl untuk Meningkatkan Kekuatan Otot Tungkai pada Pemain Futsal Dwi Suci Asriani; Sherly Mutiara
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 1 No. 1 (2022): April :Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v1i1.4401

Abstract

This study aims to evaluate the effectiveness of lying leg curl exercises in increasing leg muscle strength among futsal players. Optimal leg muscle strength is crucial for futsal players to enhance performance and reduce the risk of injury. The research employed an experimental method with a pre-test and post-test design, involving 20 futsal players divided into two groups: the intervention group, which participated in an 8-week lying leg curl exercise program, and the control group, which did not receive any intervention. Leg muscle strength was measured using a dynamometer before and after the training program. The results showed that the intervention group experienced a significant increase in leg muscle strength compared to the control group (p < 0.05). These findings indicate that lying leg curl exercises are effective in improving leg muscle strength among futsal players, contributing to better on-field performance. This study is expected to provide insights for coaches and athletes in designing more effective training programs to enhance muscle strength.
Efektivitas Latihan Aerobik yang dikombinasikan dengan Fisioterapi dalam Menurunkan Risiko Cedera pada Orang dengan Obesitas Rezki Amalia Nurshal; Sherly Mutiara; Fauzan Agus Santoso
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 2 No. 1 (2023): April :Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v2i1.4404

Abstract

This study aims to evaluate the effectiveness of aerobic exercise combined with physiotherapy in reducing injury risk among individuals with obesity. Obesity is a global health issue that significantly increases the risk of injuries, particularly within the musculoskeletal system. The research employed an experimental design with pre-test and post-test, involving 40 obese participants divided into two groups: an intervention group that underwent a 12-week program combining aerobic exercise and physiotherapy, and a control group that received no intervention. The intervention program included aerobic exercises designed to improve cardiovascular endurance and flexibility, alongside physiotherapy sessions focused on muscle strengthening and balance enhancement. The results showed that the intervention group experienced a significant reduction in injury risk and improvement in physical abilities compared to the control group (p < 0.05). Additionally, participants in the intervention group reported reduced pain levels and improved quality of life. These findings indicate that the combination of aerobic exercise and physiotherapy is effective in mitigating injury risks for individuals with obesity. This study provides valuable insights for healthcare practitioners in designing better rehabilitation programs for obese populations and encourages individuals to actively participate in safe and effective exercise regimens.
Hubungan Antara Umur dan Jenis Kelamin dengan Kualitas Hidup Pasien Gagal Ginjal Kronik yang Menjalani Hemodialisis Pius A. L. Berek; Yoakim Lay Un Fun Dales; Maria Fatimah W. A. Fouk
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 4 No. 1 (2025): April : Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v4i1.4419

Abstract

Hemodialysis (HD) is the main therapy for end-stage chronic kidney failure (CKF) patients. Various factors, including age and gender, influence HD patients' quality of life (QoL). Studies on the relationship between these two factors and the QoL of HD patients in the RI-RDTL border area are still limited. This study aims to analyze the relationship between age and gender and HD patients' quality of life at Mgr. Gabriel Manek Hospital, SVD Atambua. This study used an observational analytical design with a cross-sectional approach. The study sample consisted of 50 HD patients who met the inclusion and exclusion criteria. QoL was measured using the WHOQoL instrument, and data were analyzed using the chi-square statistical test. The results showed no significant relationship between age and the quality of life of HD patients (p = 0.245). In addition, gender also had no significant relationship with the quality of life of HD patients (p = 0.643). Age and gender were not significantly related to the quality of life of HD patients. Other more influential factors need to be studied further to improve the quality of life of HD patients.
Faktor-Faktor yang Berhubungan dengan Kekurangan Energi Kronik (KEK) pada Ibu Hamil di Wilayah Kerja Puskesmas Putri Ayu Kota Jambi Leony Lorenza; Usi Lanita; Silvia Mawarti Perdana; Asparian, Asparian; Sri Astuti Siregar
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 4 No. 1 (2025): April : Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v4i1.4428

Abstract

Chronic Energy Deficiency (CED) is a manifestation of malnutrition characterized by an inadequate energy intake over a prolonged period in pregnant women, resulting in adverse health outcomes due to a relative or absolute deficiency of one or more essential nutrients. The 2023 SKI results indicate that malnutrition among pregnant women remains a problem, with nearly 3 out of 10 pregnant women experiencing anemia and 17% at risk of CED. According to data from the Jambi City Health Office, Putri Ayu Public Health Center (Puskesmas Putri Ayu) has the highest number of CED cases, with 67 affected pregnant women. The main objective of this study is to explain the underlying factors contributing to the high prevalence of Chronic Energy Deficiency (CED) and to inform the development of evidence-based health interventions aimed at reducing this condition. This study employed a quantitative research method with a case-control design. The sampling technique used was purposive total sampling, involving 78 pregnant women in the Putri Ayu Public Health Center area, Jambi City. Data collection was conducted in October 2024, using a questionnaire as the research instrument. Data were analyzed using the chi-square test. The results showed a significant relationship between CED and parity (p=0.034), anemia (p=0.013), attitude (p=0.000), and the role of health workers (p=0.000). No significant relationship was found between CED and age (p=1.000), pregnancy spacing (p=0.615), and knowledge (p=0.359) in pregnant women. The findings indicate that parity, anemia, attitude, and the role of health workers are significantly associated with the occurrence of CED in pregnant women, while age, pregnancy spacing, and knowledge are not significantly associated.
Pendekatan Kimia Medisinal dalam Optimasi Senyawa Bioaktif dari Bahan Alam sebagai Kandidat Obat Antikanker Saeful Amin; Neng Padia Amelia; Tiara Oktavia Ramadhan; Silvia Dwi Putri
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 4 No. 1 (2025): April : Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v4i1.4430

Abstract

Cancer is one of the leading causes of death in the world, with the incidence rate continuing to increase every year. Conventional treatments such as chemotherapy and radiotherapy often have limitations, especially related to selectivity towards cancer cells and toxic side effects caused to normal cells. Therefore, an alternative approach that is more effective and safe is needed. One promising approach is the utilization of bioactive compounds from natural materials that are optimized through a medicinal chemistry approach. This study aims to examine the potential of natural compounds such as epigallocatechin gallate (EGCG) from green tea, berberine from Berberis vulgaris, curcumin from turmeric (Curcuma longa), and cardiotonic steroids (CTS) from Digitalis purpurea and Nerium oleander as anticancer agents, as well as their optimization strategies through structural modification, increased stability, and modern delivery technology. The method used is a systematic literature review of scientific articles from 2020 to 2025 obtained through the PubMed, ScienceDirect, and Google Scholar databases. The results of the study indicate that these compounds have various anticancer mechanisms of action, such as apoptosis induction, cell cycle inhibition, and activation of specific signaling pathways such as PI3K/Akt, MAPK, and ferroptosis. However, challenges such as low bioavailability, poor stability, and toxicity are still obstacles in their application. Through a medicinal chemistry approach, these compounds can be structurally modified or reformulated to improve their clinical effectiveness. In conclusion, the combination of natural wealth with medicinal chemistry innovation opens up great opportunities in the development of more selective, effective, and safe anticancer therapies in the future.
Gambaran Kadar Gula Darah dan Tekanan Darah Penderita Diabetes Melitus Tipe 2 di Puskesmas Kalibagor Azzalia Nur Rahma; Suci Khasanah; Indri Heri Susanti
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 4 No. 1 (2025): April : Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v4i1.4445

Abstract

Type 2 diabetes mellitus is a chronic disease caused by metabolic disorders, characterized by impaired insulin secretion and action, with its prevalence continuously increasing. This study aims to describe blood glucose levels and blood pressure in patients with type 2 diabetes mellitus at the Kalibagor Health Center based on respondent characteristics. The method used is descriptive quantitative with a cross-sectional design, involving 50 patients with type 2 diabetes mellitus selected through total sampling technique. Data were collected through random blood glucose tests, blood pressure measurements, and interviews regarding smoking habits and family history. The results showed that 58% of respondents had high blood glucose levels, while 70% had normal blood pressure. Respondents with a family history of diabetes were more likely to experience high blood glucose levels, while smokers had a higher risk of experiencing high blood pressure. This study also found the influence of age, gender, and family history on blood glucose and blood pressure levels. Therefore, further education on healthy lifestyle and risk factor management is needed to prevent further complications in patients with type 2 diabetes mellitus.
Hubungan Durasi Penggunaan Handphone Dengan Kecerdasan Emosional Pada Anak Kelas 4-6 di SD N 2 Kedungwringin Susan Venasari; Maya Safitri; Noor Yunida Triana
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 4 No. 1 (2025): April : Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v4i1.4447

Abstract

Excessive use of mobile phones can impact children's emotional intelligence development. This study aims to analyze the relationship between the duration of mobile phone use and emotional intelligence among students in grades 4–6 at SD Negeri 2 Kedungwringin. This research employed a quantitative approach with a cross-sectional design. The sample consisted of 43 students selected using accidental sampling. Data were collected through a questionnaire that had been tested for validity and reliability. Data analysis was conducted using the Spearman Rank test. The results showed that the majority of students used mobile phones for a short duration (<2 hours) at 58.1%, moderate duration (2–3 hours) at 27.9%, and excessive duration (>3 hours) at 14.0%. Statistical analysis revealed a significant negative correlation between the duration of mobile phone use and children’s emotional intelligence, with a p-value of 0.010 (<0.05) and a correlation coefficient of -0.387. This indicates that the shorter the duration of mobile phone use, the better the child's emotional intelligence. The conclusion of this study is that there is a significant relationship between the duration of mobile phone use and the emotional intelligence of students in grades 4–6. Therefore, it is recommended that parents and teachers supervise and regulate children's mobile phone usage to support healthy and optimal emotional development.
Hubungan Pengetahuan Dengan Perilaku Pemeriksaan IVA (Inspeksi Visual Dengan Asam Asetat) Pada Wanita Usia Subur di Wilayah Kerja Puskesmas Kowel Berliana Ayuning Asmara
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 4 No. 1 (2025): April : Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v4i1.4449

Abstract

Cervical cancer is a deadly disease and ranks as the fourth most common cancer among women, according to the World Health Organization. In Indonesia, it is the second most prevalent cancer affecting women. Visual Inspection with Acetic Acid (VIA) is an early screening method to detect cervical cancer, yet its coverage remains low in several areas of East Java. This study aims to examine the relationship between knowledge and VIA screening behavior among women of reproductive age in the working area of Kowel Public Health Center. The study employed an analytical observational design with a cross-sectional approach. A total of 70 respondents were selected using accidental sampling. Data were collected through questionnaires assessing both knowledge and VIA screening behavior. Data analysis was conducted using the chi-square test. The results showed that 38 respondents had good knowledge, while 32 had poor knowledge. The chi-square test yielded a p-value of 0.494 (p > 0.05) and a prevalence ratio (PR) of 1.684. These results indicate no significant relationship between knowledge and VIA screening behavior. However, respondents with good knowledge were 1.684 times more likely to undergo VIA screening than those with poor knowledge. It is recommended that the Kowel Health Center enhance its educational efforts through more engaging and creative counseling methods using media tools such as brochures, leaflets, posters, and animated videos, delivered both directly and via social media, to attract public interest.
Hubungan Kepatuhan Minum Obat dengan Kejadian Cacat kusta di Puskesmas Batumarmar Pamekasan Vadya Friska
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 4 No. 1 (2025): April : Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v4i1.4462

Abstract

Morbus Hansen, or leprosy, is a chronic infectious disease caused by the bacterium Mycobacterium leprae. There are two types of leprosy, namely MB (Multi Bacillary) and PB (Pauci Bacillary). According to the WHO, the level of disability due to leprosy is divided into three levels: Level 0, Level 1, and Level 3. This study is an analytic observational study using a cross-sectional research design, involving 45 respondents selected through total sampling technique. Data collection was carried out by filling out a questionnaire consisting of questions regarding leprosy medication compliance. Data analysis used the chi-square test and prevalence rate. The results showed no association between medication compliance (p=0.092, PR=2.0) and the incidence of leprosy disability at the Batumarmar Health Center, Pamekasan Regency. The conclusion of this study indicates that although theoretically adherence to medication can lead to disability in leprosy patients, the results of this study show something different. The difference between the results of this study and the theory may be due to other factors affecting disability. The suggestion is that the health center is expected to improve the monitoring system to evaluate patient compliance with treatment. Support from medical personnel and families is also needed to encourage patients to be more consistent in undergoing therapy.
Tingkat Pengetahuan, Sikap, dan Perilaku Warga Kecamatan Ngaliyan Mengenai Nevus Pigmentosus Puguh Riyanto; Danisa Diandra Safarina; Dini Hisan Wijdani; Cindy Cindy
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 4 No. 1 (2025): April : Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v4i1.4490

Abstract

Nevus pigmentosus is a benign skin lesion that originates from the proliferation of melanocytes and has the potential to develop into melanoma, one of the most dangerous skin cancers. This study aims to evaluate the level of knowledge, attitudes and behavior of the people of Ngaliyan District regarding nevus pigmentosus. The design of this research is descriptive observational with a quantitative approach. Data was collected through questionnaires from 40 respondents using techniques convenience sampling. The results showed that 50% of respondents had good knowledge, 55% had a positive attitude, but only 47.5% had good behavior towards preventing and treating nevus pigmentosus. No significant relationship was found between age and gender on behavior, as well as between knowledge and attitudes on behavior. These findings indicate the need for increased education and health promotion to encourage better preventive actions in society.

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