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Jurnal Kedokteran Gigi Terpadu
Published by Universitas Trisakti
ISSN : 27160718     EISSN : 26856867     DOI : https://doi.org/10.25105/jkgt.v4i1
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology
Jurnal Kedokteran Gigi Terpadu publishes articles and scientific work from Researches, Case Reports and Literature Reviews in Dentistry and Dental Science. The scopes vary from: Dental Surgery, Dental Forensics, Oral Biology, Oral Medicine, Dental Public Health and Preventive Dentistry, Paediatric Dentistry, Dental Materials and Technology, Conservative Dentistry,Orthodontics,Periodontics,Prosthodontics,Dental Radiology.
Arjuna Subject : Kedokteran Gigi - Bedah Mulut
Articles 380 Documents
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The effectiveness of spatholobus littoralis hassk ethanol extract against fungal growth of candida albicans Verent Novianti Liunardy; Enny Marwati Suwandi
Jurnal Kedokteran Gigi Terpadu Vol. 5 No. 1 (2023): Jurnal Kedokteran Gigi Terpadu
Publisher : Fakultas Kedokteran Gigi Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/jkgt.v5i1.17181

Abstract

Candida albicans is a normal oral flora which has a virulence factor that is closely associated with Oral Candidiasis. Both bacteria have a symbiotic relationship in growth and production of biofilms. Spatholobus littoralis Hassk stem are often not known for their benefits so they are not utilized optimally and effectively. Spatholobus littoralis Hassk stem contains active ingredients in the form of tannins, alkaloids, triterpenoids, saponins, and flavonoids which are antifungal. Objectives: To determine the antifungal effects of ethanol extract bajakah tampala stem (Spatholobus littoralis Hassk) on C. albicans. Methods: In vitro laboratory experiment with post test only control group design. The test solutions used were ethanol extract of bajakah tampala stem (Spatholobus littoralis Hassk) 6.25%, 12.5%, 25%, 50% and 100%, nystatine as a positive control, and aquades 10% as a negative control. The antifungal test was carried out using the plate count method. Results: All concentrations of the extracts has a antifungal effect on C. albicans compared to the negative control (p<0,05). Conclusion: The ethanol extract of Spatholobus littoralis Hassk stem is effective in inhibiting the growth of the Candida albicans. Further studies on toxicity of Spatholobus littoralis Hassk stem ethanol extract on Candida albicans are necessary.
Efek potensiasi kombinasi sefadroksil dan ekstrak camellia sinensis terhadap pertumbuhan aggregatibacter actinomycetemcomitans Dan porphyromonas gingivalis Karyn Priscila; Didi Nugroho Santosa
Jurnal Kedokteran Gigi Terpadu Vol. 5 No. 1 (2023): Jurnal Kedokteran Gigi Terpadu
Publisher : Fakultas Kedokteran Gigi Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/jkgt.v5i1.17184

Abstract

Background: Cefadroxil, betalactam antibiotic belonging to cephalosporin class, is a drug of choice for treating periodontal infection. Previous studies reported that addition of green tea (Camellia sinensis) extract to betalactam antibiotics has shown synergistic antibacterial effect. Objective: To examine the antibacterial effect of GTE combined with cefadroxil on A. actinomycetemcomitans and P. gingivalis growth. Methods: In vitro experimental with post-test-only control design, conducted at MiCORE Laboratory, Trisakti University Faculty of Dentistry. There were 8 treatments: combination of cefadroxil 8 µg/mL with GTE 3,125 mg/mL, 6,25 mg/mL, and 12,5 mg/mL, GTE 3,125 mg/mL, 6,25 mg/mL, and 12,5 mg/mL, cefadroxil 16 µg/mL, and NaOH 0,1 N. Results: In treatment of solely GTE and NaOH 0,1, no inhibition zones were found. Meanwhile, combination of cefadroxil 8 µg/mL with GTE 3,125 mg/mL, 6,25 mg/mL, and 12,5 mg/mL, and cefadroxil 16 µg/mL inhibited both bacteria’s growth. Treatment of cefadroxil 8 µg/mL combined with GTE 3,125 mg/mL resulted in the largest inhibition zone. One-way ANOVA test showed significant difference, then post hoc test showed that combination of cefadroxil 8 µg/mL with GTE 3,125 mg/mL and 6,25 mg/mL were not significantly different from the positive control. Conclusion: Potentiation effect occurred on combination of cefadroxil 8 µg/mL with GTE 3,125 mg/mL and 6,25 mg/mL against A. actinomycetemcomitans and P. gingivalis growth. Green tea extract could increase cefadroxil antibacterial effect up to twice larger.
Pengetahuan dokter gigi mengenai pencabutan gigi pada pasien terapi bisfosfonat Jonathan Gavriel; Anggraeny Putri Sekar Palupi
Jurnal Kedokteran Gigi Terpadu Vol. 5 No. 1 (2023): Jurnal Kedokteran Gigi Terpadu
Publisher : Fakultas Kedokteran Gigi Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/jkgt.v5i1.17197

Abstract

Background: Appropriate dental extraction management with osteoporosis patient that consume bisphosphonate is the best way to prevent bisphosphonate related osteonecrosis of the jaw Objective: evaluate the dentist knowledge and awareness in West Jakarta about dental extraction management in patient with osteoporosis that consume bisphosphonate Methods: This research method is a descriptive observational study with a cross-sectional design with 97 respondents. The data was collected through a questionnaire addressed to West Jakarta-based dentists, and the data was then displayed in the form of a graphic and percentage. The data obtained was then categorized into 3 level which are high if the respondents have ≥80 score, average if the respondents have 60-70 score and low if the respondents have score ≤50 Result: there are 85,54% respondents with a low level of knowledge, 10,31% who have average level of knowledge and 5,15% who have low level of knowledge. Conclusion: Dentists level of knowledge in West Jakarta about dental extraction with osteoporosis patients under bisphosphonate treatment is categorized low.
Issue Information Vol 5 No 1 (2023) Admin JKGT
Jurnal Kedokteran Gigi Terpadu Vol. 5 No. 1 (2023): Jurnal Kedokteran Gigi Terpadu
Publisher : Fakultas Kedokteran Gigi Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/jkgt.v5i1.17198

Abstract

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Peran igf-1 dan let-7 dalam morfogenesis gigi ditinjau dari sel punca mesenkimal pulpa gigi Endriyana, Jessica; Aryani Hayuningtyas, Ria
Jurnal Kedokteran Gigi Terpadu Vol. 6 No. 1 (2024): Jurnal Kedokteran Gigi Terpadu
Publisher : Fakultas Kedokteran Gigi Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/jkgt.v6i1.19136

Abstract

Tooth development is a complex process involving the interaction between dental epithelium and mesenchymal tissues. IGF-1 plays a crucial role in regulating cell proliferation, differentiation, apoptosis, and migration. Its significance is particularly notable during the proliferation and differentiation stages of root development, as well as in the stem cells derived from the apical papilla responsible for root pulp and dentin formation. IGF-1 exhibits osteoconductive potential in bone healing by modulating osteoclasts in bone resorption and osteoblasts in bone formation. Stem cells from dental pulp or apical papilla represent a mesenchymal stem cell or progenitor population that forms calcium nodules in osteo/odontogenic media. This study aims to elucidate the roles of IGF-1 and Let-7 in tooth morphogenesis, utilizing the PRISMA guidelines for data collection. A total of 12 literature sources were identified, with 3 articles published in the last 5 years. Only 5 articles were selected for inclusion in this study. Further exploration of IGF-1/IGF-1R/hsa-let-7c modulation in odonto/osteogenic differentiation holds promise for future tooth regeneration. IGF-1 enhances the size of tooth bud cultures, suggesting potential applications in genetic engineering for tooth morphogenesis. IGF-1 plays a crucial role in odontogenic proliferation and differentiation.
Pengaruh stunting terhadap perkembangan kognitif pada balita hingga remaja Natassya, Priska; Soesanto, Sheila
Jurnal Kedokteran Gigi Terpadu Vol. 6 No. 1 (2024): Jurnal Kedokteran Gigi Terpadu
Publisher : Fakultas Kedokteran Gigi Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/jkgt.v6i1.19137

Abstract

The first five years of childhood are a period or stage of age that determines human quality in adulthood. The critical period of children up to the age of the first two years is a period called the window of opportunity that requires nutritional support, special stimulus, and intervention. The Problem of Lack of Protein Energy (KEP) is one of the main nutritional problems that occur in toddlers and is very influential on the child's growth process. To find out if toddlers are stunted, the World Health Organization (WHO) used the growth standard as a reference by measuring the value of Z (Z score). There are 3 indicators, namely weight for length (WLZ), length for age (LAZ), and weight for age (WAZ). If the child is stunted, then the Z Standard Deviation (SD) score in the LAZ score is less than -2. To measure motoric capability, MSEL: AGS (Mullen Scales of Early Learning: AGD Edition) can be used. This method is used to measure cognition in children by measuring 5 cognitive scales i.e. Gross motor (GM), fine motor, visual capture, receptive language, and expressive language. This stunting condition can affect the cognitive development and brain growth of the child. Cognitive decline can lead to a lack of productivity and can decrease the learning achievement of children, even to adolescence
Penggunaan Gigi Tiruan pada Lansia dengan Obstructive Sleep Apnea Chandra Dwidjayanti, Siti; Kurniawati, Isnaeni; Marpaung, Carolina
Jurnal Kedokteran Gigi Terpadu Vol. 6 No. 1 (2024): Jurnal Kedokteran Gigi Terpadu
Publisher : Fakultas Kedokteran Gigi Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/jkgt.v6i1.19168

Abstract

A person who has reached the elderly stage will have an experienced degenerative process that causes several disorders. Changes in the masticatory function due to the loss of the remaining teeth can cause a transformation not only in the mastication system but also in the upper airway system of respiration. This is due to orofacial deformation, tongue retraction while in the resting position, occlusal vertical dimension changes, and a decrease in facial height. Obstructive Sleep Apnea (OSA) is a sleep breathing disorder with 17 % prevalence rate in adults and increases up to 49% in the elderly stage. A complete denture can be a rehabilitative treatment option for the elderly OSA patient. Wearing dentures during sleep is against the principles of dentistry because it can cause the tongue to be positioned posteriorly. However, people, mostly women, still wears denture while sleeping. This might further increase the obstruction of upper airway system.
Insights into periodontitis: pathogenesis, host response, and antibiotic strategies Aryani Hayuningtyas, Ria; Endriyana, Jessica; Natassya, Priska
Jurnal Kedokteran Gigi Terpadu Vol. 6 No. 1 (2024): Jurnal Kedokteran Gigi Terpadu
Publisher : Fakultas Kedokteran Gigi Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/jkgt.v6i1.19185

Abstract

This paper provides a comprehensive exploration of periodontitis, a persistent and multifaceted inflammatory condition impacting tooth-supporting structures. The authors investigate the intricate relationship between causative factors, local microbiota, and the host immune response. The disarrayed regulation of cytokines, specifically IL-1, IL-6, and TNF, is highlighted for its pivotal role in triggering or hastening periodontitis onset. The study delves into the host response, emphasizing the delicate equilibrium needed between the immune system and microbiota. The categorization of periodontal pathogenic bacteria, with a focus on the highly pathogenic Phorphyromonas gingivalis and its virulence factors, is explored. Antibiotic efficacy in the context of rising resistance is discussed, encompassing commonly used antibiotics and proposing alternative strategies like plant extracts and bacteriocins. The study advocates for comprehensive therapeutic approaches that integrate antibiotics with alternative methods to effectively address the complex nature of periodontal diseases
Perubahan Warna Pada Bahan Restorasi Resin Komposit Nanofiller Terhadap Perendaman Saliva Buatan Dengan pH 5 Widyastuti, Wiena; Tri Septiani, Afifa
Jurnal Kedokteran Gigi Terpadu Vol. 6 No. 1 (2024): Jurnal Kedokteran Gigi Terpadu
Publisher : Fakultas Kedokteran Gigi Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/jkgt.v6i1.20795

Abstract

Background: The high level of public awareness regarding aesthetic values influences the evolution and selection of restoration materials. Nanofiller composite resin is an option in aesthetic restoration because it has good aesthetic qualities, mechanical properties and high wear resistance. Color changes that occur in nanofiller composite resin are undesirable because they disturb the aesthetic value and appearance. Color changes in restoration materials are influenced by the acidic pH contained in artificial saliva. Objective: This study aims to determine the effect of artificial saliva with a pH of 5 on the color change of nanofiller composite resin restoration materials. Methods: The research object is a nanofiller composite resin with a diameter of 10 mm, and a thickness of 2mm. The research was carried out by soaking nanofiller composite resin in artificial saliva and distilled water solution. The study was divided into 2 groups, namely the treatment group and the control group. Which is placed in an incubator at a temperature of 37˚ C for 24 hours. In the control group, samples were soaked in distilled water for 24 hours, and repeated for 7 days. In the treatment group, samples were soaked in artificial saliva for 4 hours, repeated for 7 days, followed by immersion in distilled water. The color parameters of the research subjects were measured using a Vita Easyshade V spectrophotometer before and after immersion in the control and treatment groups on the 7th day. The measurement results data after carrying out the normality test, T-test (dependent), and Wilcoxon test. Results: The results of this study showed a significant color change (p<0.05). Conclusion: There is an effect of artificial saliva with a pH of 5 on the color change of the nanofiller composite resin material.
Efek Antibakteri dan Antibiofilm Minyak Atsiri Cendana India (Santalum album L.) Terdahap Streptococcus sanguinis dan Aggregatibacter actinomycetemcomitans (in vitro) Tumaang, Chelsy Clarya; Binartha, Ciptadhi Tri Oka
Jurnal Kedokteran Gigi Terpadu Vol. 6 No. 1 (2024): Jurnal Kedokteran Gigi Terpadu
Publisher : Fakultas Kedokteran Gigi Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/jkgt.v6i1.20796

Abstract

Background: Periodontal disease is caused by the accumulation of bacteria in dental plaque that causes inflammation of tooth supporting tissues. Streptococcus sanguinis and Aggregatibacter actinomycetemcomitans involved in pathogenesis of periodontal disease. Prevention of periodontal disease is done by chemical plaque control using chlorhexidine. However, the use of chlorhexidine causes adverse effects. The alternative of chlorhexidine is Indian sandalwood essential oil extract. Goals: To determine the effect of Indian sandalwood essential oil in inhibiting growth and biofilm formation of Streptococcus sanguinis and Aggregatibacter actinomycetemcomitans. Methodology: 100% Indian sandalwood essential oil extract was dissolved using Tween 20 to concentrations of 50%, 25%, 12.5%, 6.25%, 3.125%, and 1.5625%. Streptococcus sanguinis and Aggregatibacter actinomycetemcomitans were cultured for 24 hours in BHI-B at 37°C. Antimicrobial test used the microdilution method and were calculated using formula (CFU/mL). Biofilm test was carried out using the biofilm assay method incubated for 1 hour, 3 hours, and 24 hours. Biofilm assay results were calculated using microplate reader 490 nm. Results: Minimal inhibition Concentration (MIC) Streptococcus sanguinis and Aggregatibacter actinomycetemcomitans was obtained at 50%. The best concentration of Indian sandalwood essential oil in inhibiting biofilm formation of Streptococcus sanguinis was 50%. The best concentration in inhibiting Aggregatibacter actinomycetemcomitans biofilm formation for 1 hour incubation was 25%, 3 hours and 24 hours incubation was 12.5%. Conclusion: Indian sandalwood essential oil extract proved effective in inhibiting growth and biofilm formation of Streptococcus sanguinis and Aggregatibacter actinomycetemcomitans.  

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