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Jurnal Kedokteran Gigi Terpadu
Published by Universitas Trisakti
ISSN : 27160718     EISSN : 26856867     DOI : https://doi.org/10.25105/jkgt.v4i1
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology
Jurnal Kedokteran Gigi Terpadu publishes articles and scientific work from Researches, Case Reports and Literature Reviews in Dentistry and Dental Science. The scopes vary from: Dental Surgery, Dental Forensics, Oral Biology, Oral Medicine, Dental Public Health and Preventive Dentistry, Paediatric Dentistry, Dental Materials and Technology, Conservative Dentistry,Orthodontics,Periodontics,Prosthodontics,Dental Radiology.
Arjuna Subject : Kedokteran Gigi - Bedah Mulut
Articles 380 Documents
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Infeksi odontogenik: phlegmon dan selulitis Putri Sekar Palupi , Anggraeny
Jurnal Kedokteran Gigi Terpadu Vol. 6 No. 1 (2024): Jurnal Kedokteran Gigi Terpadu
Publisher : Fakultas Kedokteran Gigi Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/jkgt.v6i1.20885

Abstract

Infeksi gigi merupakan penyakit yang umum terjadi di masyarakat. Infeksi gigi terdapat yang ringan dan juga ada yang berkembang menjadi komplikasi serius dan fatal. Phlegmon dan selulitis termasuk dalam komplikasi dari infeksi gigi. Jika tidak segera dilakukan perawatan khusus dengan tepat, dapat menjadi berbahaya dan fatal. Oleh karena itu, memahami prinsip pengelolaan phlegmon dan selulitis merupakan hal yang penting bagi para praktisi.Infeksi odontogenik merupakan salah satu patologi yang paling umum terjadi di daerah mulut dan maksilofasial. Infeksi biasanya berkembang melalui tiga fase: inokulasi, selulitis, dan pembentukan abses. Selulitis wajah yang berasal dari gigi adalah peradangan pada jaringan adiposa seluler yang terletak pada rongga-rongga yang mengelilingi rahang bawah dan rahang atas, yang berkembang dari daerah yang mengalami infeksi gigi. Selain itu, phlegmon dasar mulut atau yang biasa disebut dengan Ludwig’s angina juga merupakan salah satu komplikasi infeksi odontogenik. Phlegmon dasar mulut merupakan selulitis supuratif difus akut yang menyebar terutama pada jaringan ikat longgar, yang dimulai dari ruang submandibular. Infeksi odontogenik seperti selulitis dan phlegmon merupakan salah satu keadaan darurat yang harus segera ditangani oleh dokter gigi. Penatalaksanaan yang diperlukan pada selulitis yaitu dengan menghilangkan penyebab infeksi, dan melakukan drainase bedah. Selain itu, penatalaksanaan pada kasus phlegmon dilakukan dengan cara menjaga pernapasan, terapi antibiotik agresif dan dekompresi ruang submental, sublingual dan submandibular.
Metode uji sitotoksisitas biomaterial dengan  bentuk scaffold padatan dan berpori spons Belatriks Kalangit, Ruth; Octarina
Jurnal Kedokteran Gigi Terpadu Vol. 6 No. 1 (2024): Jurnal Kedokteran Gigi Terpadu
Publisher : Fakultas Kedokteran Gigi Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/jkgt.v6i1.20886

Abstract

Three-dimensional scaffolds play a crucial role in supporting cell growth and tissue regeneration, especially in bone regenerative applications. Their utilization in dentistry demands effective cytotoxicity assessment, particularly for sponge-shaped scaffolds with a unique porous structure fostering a complex environment for cell growth. Therefore, the imperative lies in selecting cytotoxicity testing methods suitable for these characteristics. Relevant methods for such scaffolds include MTS, Alamar Blue, ATP, CCK-8, and MTT assays. MTS assay efficiently measures cell viability in a three-dimensional setting, while Alamar Blue and CCK-8 assays, with their water-soluble nature and high reproducibility, prove advantageous. ATP assay provides direct insights into cellular metabolic activity, and MTT assay assesses cell viability based on enzymatic capabilities. Due to their water-soluble characteristics, minimizing additional extraction steps, and ensuring high reproducibility, Alamar Blue and CCK-8 emerge as the most fitting options for cytotoxicity assessment in dentistry's sponge-shaped scaffolds.
Potensi ekstrak daun gamal sebagai bahan antikanker terhadap sel kanker rongga mulut Annistri, Savrinda; Sandra, Ferry; Oetomo Roeslan, Boedi
Jurnal Kedokteran Gigi Terpadu Vol. 6 No. 1 (2024): Jurnal Kedokteran Gigi Terpadu
Publisher : Fakultas Kedokteran Gigi Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/jkgt.v6i1.20888

Abstract

Latar Belakang: Kanker rongga mulut merupakan karsinoma kepala dan leher yang tercatat sebagai peringkat ke-6 keganasan paling sering terjadi. Salah satu tumbuhan yang berpotensi sebagai terapi alternatif karsinoma kepala dan leher adalah daun Gamal atau yang selanjutnya disebut Gliricidia sepium Jacq karena memiliki zat antioksidan yang sering digunakan oleh masyarakat sebagai pengobatan tradisional. Tujuan: Review ini bertujuan untuk melihat kemungkinan penelitian masa depan tentang kanker mulut menggunakan ekstrak etanol daun G. sepium. Metode: Referensi pada review ini menggunakan pencarian jurnal terkait di PubMed, Google Scholar, laporan resmi dan jurnal kesehatan lainnya dengan kata kunci pencarian “kanker mulut”, “anti-kanker”, “Gliricidia sepium Jacq.”, “antioksidan” dan “apoptosis” dari tahun 2006 – 2023. Hasil Penelitian: Daun G. sepium kerap digunakan sebagai obat tradisional oleh masyarakat. Dilaporkan kegunaannya dalam pengobatan tradisional dapat dikaitkan dengan aktivitas farmakologisnya yang berfungsi sebagai ekspektoran, sedatif, supuratif, anti bakteri, anti jamur, dan anti virus. Penelitian sebelumnya didapatkan senyawa-senyawa metabolit sekunder yang terkandung sebagian besar dapat digunakan sebagai bahan anti-kanker. G. sepium juga dilaporkan memiliki kemampuan dalam menginduksi apoptosis pada kanker kolon HCT116, kanker payudara HCC 1935 dan prostat DU 145, serta berdasarkan hasil penelitian ekstrak petroleum eter G. sepium sangat anti proliferasi pada kanker prostat DU145. Namun, belum terdapat penelitian mengenai potensi G. sepium sebagai bahan anti kanker dalam menangani kanker mulut. Kesimpulan: Berdasarkan temuan, dapat disimpulkan bahwa daun G. sepium mampu berperan sebagai agen anti-kanker karena senyawa yang terkandung didalamnya. Penelitian lebih lanjut diperlukan untuk melihat aktivitas anti kanker G. sepium terhadap kanker mulut.
Potensi stenochlaena palustris (burm.f.) bedd. Sebagai Antikanker dalam perawatan kanker mulut Yuliani Taramalinda, Elizabeth; Sandra, Ferry; Oetomo Roeslan, Boedi
Jurnal Kedokteran Gigi Terpadu Vol. 6 No. 1 (2024): Jurnal Kedokteran Gigi Terpadu
Publisher : Fakultas Kedokteran Gigi Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/jkgt.v6i1.20889

Abstract

Background : The number of deaths due to cancer nearly reached 10 million in 2020, with approximately 90% of them attributed to oral cancer, which falls under the category of head and neck cancers. S. palustris has potential as a chemopreventive agent due to its secondary metabolites, including flavonoids and alkaloids, which have demonstrated inhibitory effects on cancer cell proliferation and induction of apoptosis. Objective : This research aims to assess the potential extract from S. palustris as an anticancer agent in the treatment of oral cancer. The study involves investigating the inhibitory effects of the extract on cancer cell proliferation and its ability to induce apoptosis. Method: The references for this review were sourced from PubMed, Google Scholar, official reports, and global health organizations' websites using search terms like "oral cancer," "anticancer," "Stenochlaena palustris," and "apoptosis" spanning 2013 to 2023. Both English and Indonesian language publications were included in this review. Main finding : The S. palustris extract, associated with diverse pharmacological activities, holds potential as an aphrodisiac, free radical scavenger, antibacterial, anticancer, and larvicidal agent. The impact of this extract on oral cancer cells requires further research to assess its potential in combating oral cancer. Conclusion : Several studies have reported of S. palustris has anticancer potential against diverse cancer cell lines. However, to date, there has been no specific investigation into the anticancer activity of S. palustris against oral cancer. Hence, additional research on the efficacy of S. palustris against oral cancer is warranted to validate its potential in oral cancer therapy.
Aktivitas Antioksidan dengan Metode DPPH dan ABTS Terhadap Ekstrak Etanol Daun Amaranthus hybridus L. Dewi Ranggaini, Monica; Halim, Johni; Aurelia Tjoe, Michelle
Jurnal Kedokteran Gigi Terpadu Vol. 6 No. 1 (2024): Jurnal Kedokteran Gigi Terpadu
Publisher : Fakultas Kedokteran Gigi Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/jkgt.v6i1.20891

Abstract

Background: Cancer, a degenerative disease, arises from free radicals in the body, which can be counteracted by antioxidants. Amaranthus hybridus L., a vegetable rich in antioxidant compounds like flavonoids, requires extraction to harness these compounds. This extraction uses the maceration technique with 70% ethanol. Antioxidant activity is tested using methods like DPPH and ABTS assays, with the IC50 value indicating effectiveness. Purpose: To determine the difference in antioxidant activity of A. hybridus L. leaves ethanol extract with DPPH and ABTS methods. Method: Laboratory experimental research. Simplicia leaves of A. hybridus L. in 70% ethanol solvent were extracted using maseration method. The antioxidant activity was tested in the sample and the ascorbic acid using DPPH and ABTS methods at wavelenghts 517 nm and 745 nm. Sample absorbance was measured using microplate reader. Result: IC50 values of A. hybridus L. leaves ethanol extract with DPPH and ABTS methods were 54,99 µg/mL and 71,45 µg/mL, for ascorbic acid using DPPH and ABTS methods were 0,62 µg/mL and 3.13 µg/mL. Conclusion: The antioxidant activity of A. hybridus L. leaves ethanol extract with DPPH method has stronger antioxidant than ABTS method.
Potensi Alisin bagi Kedokteran Gigi Fonda, Gloria; Natassya, Priska; Nugrogo, Didi
Jurnal Kedokteran Gigi Terpadu Vol. 6 No. 1 (2024): Jurnal Kedokteran Gigi Terpadu
Publisher : Fakultas Kedokteran Gigi Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/jkgt.v6i1.20892

Abstract

Allicin is an organosulfur compound commonly found in garlic that has been used as a traditional medicine. It can act as an antibacterial, antivirus, antifungal, anti-inflammatory, anticancer, antioxidant, and immunomodulator. Studies showed that allicin has potential to be used as a medicine to prevent caries and periodontal bacteria, prevent denture stomatitis, and alleviate oral cancer pain. It is also easy to obtain, affordable, and not toxic. Therefore, allicin has the potential to be used in the field of dentistry.
Perawatan ulang saluran akar gigi molar kanan mandibula Stefani, Rosita; Steward
Jurnal Kedokteran Gigi Terpadu Vol. 6 No. 1 (2024): Jurnal Kedokteran Gigi Terpadu
Publisher : Fakultas Kedokteran Gigi Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/jkgt.v6i1.20897

Abstract

Background: An inadequate root canal treatment allows bacteria to thrive and survive, which is a major cause of endodontic failure. An appropriate treatment plan can be determined after a precise and accurate diagnosis has been made. Objective: The purpose of this case report is to demonstrate the root canal retreatment on a posterior mandibular tooth with periapical lesions. Case report: A 37-year-old female patient came with complaints of discomfort when chewing food with her lower right back tooth. The tooth had been treated ten years ago with a metal filling, which was replaced with a tooth-colored filling a year ago. Intra-oral examination of tooth 46 showed composite resin restoration on the distobuccal surface. Radiographic findings showed that there was restoration on the distal surface that reaches the floor of the pulp chamber and radiolucency in the furcation area. Root canal retreatment was performed based on the diagnosis of acute apical periodontitis et causa necrotic pulp. The treatment plan involved root canal retreatment with direct resin composite restoration. Root canal retreatment starts with the application of a rubber dam, followed by the removal of any existing restoration and caries, opening the cavity, root canal exploration, and root canal shaping. Biomechanical preparation was carried out with Protaper Hand Use with crown down technique, in conjunction with 2,5% NaOCl irrigation. The initial visit concludes with the disinfection of the root canal with calcium hydroxide. The following treatment involved a subjective and objective assessment, removal of the temporary filling, cleaning of calcium hydroxide, and final irrigation with 2,5% NaOCl, 17% EDTA, and 2% CHX. Obturation was accomplished utilizing the vertical condensation technique. The restoration was completed with composite resin. Conclusion: Root canal retreatment on teeth with acute apical periodontitis et causa necrotic pulp was successfully carried out.
Gambaran Kualitas Hidup pada Lansia Pengguna Gigi Tiruan Lepasan Lutfia Rachma, Nindya; Ayu Ratih Utari Mayun, I Gusti
Jurnal Kedokteran Gigi Terpadu Vol. 6 No. 1 (2024): Jurnal Kedokteran Gigi Terpadu
Publisher : Fakultas Kedokteran Gigi Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/jkgt.v6i1.20898

Abstract

Background: The aging process is a natural occurrence affecting individuals, influenced by various factors such as gender, employment, education level, and oral health. Tooth loss is a common consequence of aging. Removable dentures offer an alternative to rehabilitate missing teeth, replacing one or more teeth and surrounding tissues to restore function and prevent further damage. The objective of prosthodontic treatment for the elderly is to replace missing teeth with functional ones that enhance appearance, speech, and most importantly, chewing abilities. The ultimate goal is to help the elderly consume more nutrients. Objective: This study aims to assess the quality of life among senior citizens using removable dentures at the Ciracas nursing home in East Jakarta. Methods: A cross-sectional design and descriptive observational research methodology were employed. Seventy-one senior respondents aged 60 and above, using removable dentures at the Ciracas Nursing Home, participated in the study. The Oral Health Impact Profile 14 (OHIP 14) questionnaire was used for data collection. Results: Analysis revealed that 26 respondents (36.6%) reported good quality of life, 40 respondents (56.3%) reported moderate quality of life, and 5 respondents (7%) reported low quality of life. Conclusion: The quality of life of elderly residents of the Nursing Home in the Ciracas District of East Jakarta who wear removable dentures is categorized as moderate.  
Hubungan penyakit periodontal dengan covid-19 Suwandi, Trijani; Carissa Nurhasinah Wiriawan, Deandra
Jurnal Kedokteran Gigi Terpadu Vol. 6 No. 1 (2024): Jurnal Kedokteran Gigi Terpadu
Publisher : Fakultas Kedokteran Gigi Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/jkgt.v6i1.20908

Abstract

Periodontitis is a chronic, multifactorial, inflammatory disease, associated with plaque biofilms and characterized by the progressive destruction of the tooth-supporting structures. Periodontal diseases can increase the inflammatory response in patients, which might exacerbate the systemic symptoms and clinical course of coronavirus (COVID-19). The potential association of periodontitis and COVID-19 severity can be explained by the alteration in the expression of cellular receptors enhancing the virulence of SARS-CoV-2 and by periodontal pockets acting as viral reservoirs. These associations between periodontitis and COVID could be due to the fact that both diseases share common immune pathways such as the NF-κB pathway, NLRP3/IL-1β pathway, and IL-6 signaling pathway as well as common risk factors such as gender, lifestyle, and comorbidities. This suggests that the two diseases may be linked through the same genetic pathway.  
Penatalaksanaan jaringan gingiva dalam penggunaan retraction cord Pratama Sarwono, Aditya; Fitriyasari, Rahmah
Jurnal Kedokteran Gigi Terpadu Vol. 6 No. 1 (2024): Jurnal Kedokteran Gigi Terpadu
Publisher : Fakultas Kedokteran Gigi Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/jkgt.v6i1.20910

Abstract

Introduction: Tooth loss affects a person's appearance and health, impacting their quality of life. Teeth play an essential role in chewing and aesthetics, particularly the anterior teeth. Dental trauma such as fractures can affect appearance and psychology, reducing self-confidence. Currently, aesthetics is a top priority in dental care. Tooth loss leads to complex oral problems, thus missing teeth need to be replaced with dentures. Methods: This study explores the use of various gingival retraction techniques before impression taking in prosthodontic treatment. The methods analyzed include mechanical, chemical, and surgical techniques, with a focus on retraction using retraction cords soaked in hemostatic agents to ensure accurate and blood-free gingival margins before impression taking. Discussion: Accurate impressions depend on proper tooth preparation and healthy soft tissue conditions. Effective gingival retraction is crucial for obtaining good impressions, especially at the cervical and gingival margins. Mechanical methods using retraction cords are commonly used due to their effectiveness, speed, simplicity, and affordability. However, chemical methods may pose risks to the gingiva, while surgical methods are more complex. Conclusion: Accurate impressions for fixed dentures require healthy soft tissues without periodontal disease. Gingival retraction before impression taking is essential for achieving accurate impressions, ensuring that the cervical margins are well defined. Retraction methods include mechanical, chemical, and surgical approaches, with mechanical methods being the common choice due to their effectiveness and simplicity.

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