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Contact Name
Hasni Syahida
Contact Email
hsyahida@ulm.ac.id
Phone
+6287815460096
Journal Mail Official
homeostasis@ulm.ac.id
Editorial Address
Jalan Veteran No.128 Banjarmasin
Location
Kota banjarmasin,
Kalimantan selatan
INDONESIA
Homeostasis: Jurnal Mahasiswa Pendidikan Dokter
ISSN : -     EISSN : 27224333     DOI : -
Core Subject : Health, Science,
Homeostasis adalah jurnal yang berisi tulisan yang diangkat dari hasil penelitian yang memiliki fokus dan ruang lingkup di bidang kedokteran dan kesehatan. Tulisan-tulisan yang dimuat bisa dalam bentuk Original Research, Literature Review, ataupun Laporan Kasus. Homeostasis terbit tiga kali setahun pada bulan April, Agustus, dan Desember di setiap tahunnya.
Articles 481 Documents
LITERATURE REVIEW: POLA KEPEKAAN SALMONELLA TYPHI TERHADAP ANTIBIOTIK PADA PASIEN DEMAM TIFOID ANAK Batosamma, Novatalia; Muthmainah, Noor; Rahmiati, Rahmiati; Pratiwi, Dewi Indah Noviana; Hayatie, Lisda
Homeostasis Vol 6, No 3 (2023)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v6i3.11476

Abstract

Typhoid fever is one of the major health problems in the world, especially in developing countries. The highest typhoid fever morbidity is found in children, especially school age children. Patients often self-medicate with antibiotics, the main antibiotic of choice for typhoid fever in Indonesia is chloramphenicol but in some places resistance to the chloramphenicol group has been reported. When writing, related literature is examined using search results from Google Scholar and PubMed - MEDLINE, two medical journal databases. articles from 2012 to 2019 that were published in English. This literature study contained a total of 8 papers. The article published in this literature review shows the presence of resistant isolates in the Salmonella thypi antibiotic susceptibility test in the main therapy given. In some cases, they have resistance to ceftriaxone, cefuroxime, amoxicillin, ampicillin, ciprofloxacin, augmentin, fluoroquinolones, azithromycin, and nalidixic acid. Some of the drugs mentioned as sensitive to S. Typhi are Cefixime, ceftriaxone, chloramphenicol, ofloxacin, cefepime, quinolones, and third generation cephalosporins. 
KORELASI KADAR MASSA OTOT DAN KUALITAS HIDUP PADA PASIEN YANG MENJALANI HEMODIALISIS RUTIN DI RSUD ULIN BANJARMASIN Ariewardana, Angger; Rudiansyah, Mohammad; Pratiwi, Dewi Indah Noviana; Cahyawati, Wiwit Agung Sri Nur; Marisa, Dona
Homeostasis Vol 7, No 2 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v7i2.13180

Abstract

Abstract: Chronic Kidney Disease (CKD) is defined as kidney damage or a decrease in the gromerular filtration rate that occurs for 3 months or more, manifesting as kidney damage and requiring kidney replacement therapy, namely hemodialysis. CKD sufferers often experience an energy imbalance due to anorexia which increases energy needs while energy reserves are depleted. Muscle mass levels function as bone moving organs. Muscle mass will be measured using the BIA (Bioimpedance Analysis). Low muscle mass is often associated with low quality of life. Quality of life is an assessment of several aspects of life. Hemodialysis therapy will affect quality of life including lack of energy, fatigue and stress. Quality of life can be measured using the SF-36 questionnaire. This study was to regulate the correlation among muscle mass levels and the level of quality of life of routine hemodialysis patients at RSUD Ulin Banjarmasin. The research method uses analytical observational with a cross-sectional approach. The technique for taking subjects was simple random sampling of 60 subjects. Data collection was carried out by direct measurements and interviews of muscle mass levels and quality of life. Data analysis used the Komolgorov-Smirnov normality test and continued with test called Pearson correlation test. The results of data analysis showed a strong significant correlation (p=0.000, r=0.706). The results of the study concluded that muscle mass levels had a significant correlation with the level of quality of life of hemodialysis patients at RSUD Ulin Banjarmasin. Keywords: Muscle mass, quality of life, hemodialysis, BIA (Bioimpedance analysis), questionnaire QOL Short Form-36. Abstrak: Penyakit ginjal kronis (PGK) didefinisikan sebagai kerusakan ginjal atau penurunan laju filtrasi gromerulus yang terjadi selama 3 bulan atau lebih bermanifestasi sebagai kerusakan ginjal dan memerlukan terapi pengganti ginjal yaitu hemodialisis. Penderita PGK sering mengalami ketidakseimbangan energi akibat anoreksia yang meningkatkan kebutuhan energi sementara asupan energi cadangan habis. Kadar massa otot berfungsi sebagai organ penggerak tulang. Massa otot dapat diukur salah satunya dengan menggunakan alat BIA (Bioimpedance analysis). Rendahnya massa otot kerap dihubungkan dengan rendahnya kualitas hidup. Kualitas hidup merupakan penilaian beberapa aspek dalam kehidupan. Terapi hemodialisis akan mempengaruhi kualitas hidup meliputi kekurangan energi, kelelahan, dan stress. Kualitas hidup dapat diukur salah satunya menggunakan kuesioner SF-36. Tujuan penelitian ini adalah untuk mengetahui korelasi kadar massa otot dan kualitas hidup pasien hemodialisis rutin di RSUD Ulin Banjarmasin. Metode penelitian menggunakan observasional analitik dengan pendekatan cross-sectional. Teknik pengambilan subjek dengan simple random sampling sebanyak 60 subjek. Pengambilan data dilakukan dengan pengukuran dan wawancara langsung kadar massa otot dan kualitas hidup. Analisis data menggunakan uji normalitas Komolgorov-Smirnov dan dilanjutkan dengan uji korelasi Pearson. Hasil analisis data terdapat korelasi bermakna kuat (p=0,000, r=0,706). Hasil penelitian menyimpulkan kadar massa otot terdapat korelasi bermakna dengan kualitas hidup pasien hemodialis di RSUD Ulin Banjarmasin. Kata-kata kunci: Massa otot, kualitas hidup, hemodialisis, BIA (bioimpedance analysis), kuesioner QOL Short form-36.
TINGKAT PEMAHAMAN MALPRAKTIK MAHASISWA FAKULTAS KEDOKTERAN SEMESTER AKHIR ANGKATAN 2019 Uyun, Andi Quratul; Nirmalasari, Nila; Husairi, Ahmad; Aflanie, Iwan; Panghiyangani, Roselina
Homeostasis Vol 6, No 3 (2023)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v6i3.11443

Abstract

Malpractice is not only limited to the health profession but can also occur in other professions. Medical malpractice can be committed by doctors, nurses, midwives or other health workers whose actions deviate from medical standards.The problem of malpractice in health services today is being interesting topic for many people among various groups. It is proved by the many malpractice cases handled by the Honorary Council of Indonesian Medical Discipline (MKDKI). One of the reasons lies on the lack of communication between doctors or medical personnel and patients. One of the purposes of this research is to measure the level of understanding of doctor candidates about malpractice so that it is easier to follow up on it. his research used observation research method by taking data from medical students 2019 who are in the final semester to determine the students’ level of malpractice understanding. The sample of this research were decided by using purposive sampling in non-probability sampling technique. The results showed that there are 8 students (13%) in the high level,47 students (78%) in moderate level and 5 students (8%) in deficient level of malpractice understanding in the final semester students of medicine faculty at University of Lambung Mangkurat.
DAYA HAMBAT OPTIMUM KOMBINASI EKSTRAK Eichhornia crassipes DAN Pistia stratiotes TERHADAP Candida albicans Putri, Putri; Budiarti, Lia Yulia; Kaidah, Siti
Homeostasis Vol 6, No 3 (2023)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v6i3.11467

Abstract

Candida albicans (C. albicans) is an opportunistic pathogenic fungus that causes candidiasis. Eichhornia crassipes (EC) and Pistia stratiotes (PS) are known to contain antifungal bioactive compounds. This study aims to analyze the effect of the combination of EC and PS extracts on C. albicans, which produces optimum inhibition. The design of this study used a post-test only with in-vitro control group design. Combination treatment of EC and PE extracts 25%, 50%, 75%, and 100% (ratio 1:1), control of ketoconazole and 10% DMSO. Data analysis used Duncan's One-way Anova and post-hoc tests. The diameter of the inhibition zone resulting from the EC+PS combination treatment was moderate (8,63 ± 0,50 mm) to very strong (21,12 ± 0,002 mm). There was a significantly different effect between the EC+PS combination treatments (p>0,05). The inhibition zone in the EC100%+PS100% combination treatment was the largest and the effect was equivalent to that of ketoconazole (p<0,05). In conclusion, the EC+PS combination treatment produced varying optimum inhibition against C. albicans which was in line with the concentration of the EC+PS combination.
HUBUNGAN DUKUNGAN KELUARGA DENGAN KEPATUHAN KONTROL Septiana, Selfea; Heriyani, Farida; Al Audhah, Nelly
Homeostasis Vol 7, No 1 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v7i1.12408

Abstract

Abstract: Hypertension is an increase in blood pressure above normal, systolic ≥140 mmHg and diastolic ≥90 mmHg. Hypertension is a chronic disease that requires long-term treatment and must be controlled regularly to avoid complications. Family support is needed so that hypertension sufferers have regular blood pressure checks at health facilities. This study aims to determine the relationship between family support and compliance with the control of hypertension sufferers at the Kubur Jawa Community Health Center, Hulu Sungai Tengah Regency. This research is an analytical observational study with a cross-sectional approach. The research population was hypertension sufferers who visited the general polyclinic of the Kubur Jawa Community Health Center with a total of 90 research subjects selected using a simple random sampling technique. Data analysis used the chi-square test. The research results showed that 62% of control compliance was low and 52% of family support was not good with a p-value = 0.001. The research conclusion is that there is a relationship between family support and compliance with the control of hypertension sufferers at the Kubur Jawa Community Health Center, Hulu Sungai Tengah Regency. Keywords: hypertension, control compliance, family support Abstrak: Hipertensi adalah suatu peningkatan tekanan darah di atas normal, sistolik ≥140 mmHg dan diastolik ≥90 mmHg. Hipertensi merupakan penyakit kronis yang memerlukan jangka panjang dalam proses pengobatan dan harus di kontrol rutin agar tidak terjadi komplikasi. Dukungan keluarga diperlukan agar penderita hipertensi melakukan pemeriksaan tekanan darah secara rutin di fasilitas kesehatan. Penelitian ini bertujuan mengetahui hubungan dukungan keluarga dengan kepatuhan kontrol penderita hipertensi di Puskesmas Kubur Jawa Kabupaten Hulu Sungai Tengah. Penelitian ini merupakan penelitian observasional analitik dengan pendekatan cross-sectional. Populasi penelitian adalah penderita hipertensi di poliklinik umum Puskesmas Kubur Jawa dengan total subjek penelitian 90 orang dipilih dengan teknik simple random sampling. Analisis data menggunakan uji chi-square. Hasil penelitian didapatkan sebanyak 62% kepatuhan kontrol rendah dan sebanyak 52% dukungan keluarga tidak baik dengan hasil p-value = 0,001. Kesimpulan penelitian terdapat hubungan dukungan keluarga dengan kepatuhan kontrol penderita hipertensi di Puskesmas Kubur Jawa Kabupaten Hulu Sungai Tengah. Kata-kata kunci: hipertensi, kepatuhan kontrol, dukungan keluarga
HUBUNGAN INDEKS MASSA TUBUH DENGAN FRAILTY PADA LANSIA DI PPRSLU BUDI SEJAHTERA BANJARBARU Ansharullah, M Rifky; Cahyawati, Wiwit Agung Sri Nur; Yasmina, Alfi; Noor, Zairin; Wahyuni, Wahyuni
Homeostasis Vol 7, No 1 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v7i1.12380

Abstract

Abstract: Frailty is a sign of physiological and functional vulnerability in the elderly. One of the risk factors for frailty is BMI. This study aimed to determine the relationship between BMI and frailty in the elderly, using cross-sectional method. The research subjects were elderliesliving in PPRSLU Budi Sejahtera Banjarbaru, using total sampling method according to the inclusion and exclusion criteria. The independent variable was BMI and the dependent variable was frailty. Frailty was measured by physical frailty phenotype. The relationship between BMI and frailty was analyzed using the logistic regression test. A total of 40 elderlies were included; most were women with an average age of 69.8 ± 8.6 years and an average BMI of 23.4 ± 4.6 kg/m2. There were no robust/fit elderlies. Elderlies with underweight and normal BMI tended to be frail, while elderlies with overweight and obese BMI tended to be pre-frail. Increasing BMI was associated with a lower incidence of frailty compared with the pre-frail incidence, but this relationship was not significant (OR 0.53, 95%CI = 0.24-1.17). The conclusion of this research is that there is no significant relationship between BMI and frailty in the elderlies living in PPRSLU Budi Sejahtera Banjarbaru. Keywords: frailty, body mass index, elderly, physical frailty phenotype. Abstrak: Frailty merupakan tanda kerentanan fisiologis dan fungsional pada lansia. Salah satu faktor risiko frailty adalah IMT. Penelitian ini bertujuan mengetahui hubungan IMT dengan frailty pada lansia, dengan metode cross-sectional. Subjek penelitian yaitu lansia di PPRSLU Budi Sejahtera Banjarbaru, menggunakan metode total sampling sesuai kriteria inklusi dan eksklusi. Variabel bebas adalah IMT dan variabel terikatnya frailty. Frailty diukur dengan physical frailty phenotype. Hubungan IMT dan frailty dianalisis dengan uji logistic regression. Sebanyak 40 lansia diinklusi; sebagian besar perempuan dengan rerata usia 69,8±8,6 tahun dan rerata IMT 23,4±4,6 kg/m2. Tidak didapatkan lansia yang robust/fit. Lansia dengan IMT underweight dan normal cenderung frail, sedangkan lansia IMT overweight dan obesitas cenderung pre-frail. Peningkatan IMT berhubungan dengan kejadian frailty yang lebih rendah dibanding kejadian pre-frail, namun hubungan ini tidak bermakna (OR 0,53, 95%CI = 0,24-1,17). Simpulan penelitian ini adalah tidak terdapat hubungan yang signifikan antara IMT dan frailty pada lansia di PPRSLU Budi Sejahtera Banjarbaru. Kata-kata kunci: frailty, indeks massa tubuh, lansia, physical frailty phenotype
NILAI KOEFISIEN FENOL DAN DAYA HAMBAT KOMBINASI INFUS EKSTRAK DAUN SIRIH (Piper betle Linn) DAN AKAR KUNING (Fibrauera tinctoria Lour) TERHADAP Escherichia coli ATCC 25922 Amalya, Khalida Zikra; Budiarti, Lia Yulia; Biworo, Agung
Homeostasis Vol 7, No 2 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v7i2.13232

Abstract

Abstract: Transmission of infection by Escherichia coli (E.coli) can be prevented with antiseptics such as alcohol. Natural antiseptics in combination dosage forms can produce stronger antibacterial effects. Betel leaves (P.betle) and yellow roots (F.tinctoria) contain antibacterial properties. The aim of this research is to test the effect of a combination of P.betle and F.tinctoria infusion (PB+FT) on E.coli ATCC 25922. This posttest-only with control group design uses the parameters of the phenol coefficient and inhibition zone values. The treatments in the phenol coefficient test were PB+FT, 70% alcohol control, and 5% phenol in serial dilutions of 1:20-1:250. In the inhibition test using PB+FT, concentrations of 6.25%, 12.5%, 25%, 50%, 75% and 100% as well as 70% alcohol and sterile distilled water were used. The results of calculating the average value of the phenol coefficient from PB+FT, obtained a value >1 and control <1. The results of statistical tests showed that the effect in the form of an average inhibition zone was influenced by the concentration of PB+FT. The average inhibition zone of PB+FT75% is not significantly different from 70% alcohol and PB+FT100% produces a very strong inhibition zone. Conclusion, PB+FT infusion produces a strong effect against E.coli. Keywords: Fibrauera tinctoria lour roots, Piper betle Linn leaves, Escherichia coli, phenol coefficient, zone of inhibition Abstrak: Penularan infeksi oleh Escherichia coli (E.coli) dapat decegah dengan antiseptik seperti alkohol. Antiseptik alami pada bentuk sediaan kombinasi dapat menghasilkan efek antibakteri lebih kuat. Daun sirih (P.betle) dan akar kuning (F.tinctoria) memiliki kandungan bersifat antibakteri. Tujuan penelitian ini yaitu menguji efek kombinasi infus P.betle dan F.tinctoria (PB+FT) terhadap E.coli ATCC 25922. Rancangan penelitian posttest-only with control group design ini menggunakan parameter nilai koefisien fenol dan zona hambat. Perlakuan pada uji koefisien fenol yaitu PB+FT, kontrol alkohol 70%, dan fenol 5% pada serial pengenceran 1:20-1:250. Pada uji daya hambat menggunkan PB+FT menggunakan konsentrasi 6,25%, 12,5%, 25%, 50%, 75%, dan 100% serta alkohol 70% dan akuades steril. Hasil perhitungan nilai reta-rata koefisien fenol dari PB+FT, diperoleh nilai >1 dan kontrol <1. Hasil uji statistik, didapatkan efek berupa rata-rata zona hambat dipengaruhi oleh konsentrasi PB+FT. Rerata zona hambat dari PB+FT75% tidak berbeda nyata dengan alkohol 70% dan PB+FT100% menghasilkan zona hambat tergolong sangat kuat. Kesimpulan, infus PB+FT menghasilkan efek yang kuat terhadap E.coli. Kata-kata kunci: akar Fibrauera tinctoria lour, daun Piper betle Linn, Escherichia coli, koefisien fenol, zona hambat.
HUBUNGAN INTRAVESICAL PROSTATIC PROTRUSION DENGAN Q MAX UROFLOWMETRI Al-fath, Muhammad Fauzan; Sutapa, Hendra; Istiana, Istiana; Rahman, Eka Yudha; Panghiyangani, Roselina
Homeostasis Vol 6, No 3 (2023)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v6i3.11458

Abstract

Benign prostatic hyperplasia (BPH) is a benign tumor that is often found in men. IPP is a protrusion of the prostate starting from the neck of the bladder into the cavity of the bladder which results in a ball valve mechanism in the neck of the bladder thereby disrupting the flow of urine past the neck of the bladder. Uroflowmetry test is the simplest test to measuring the amount of urine that is urinated divided by the duration of micturition (ml/second). This research aims to analyze the relationship between IPP and q max of uroflowmetry measurements in BPH patients with LUTS at Ulin General Hospital, Banjarmasin. This research is analytic observational with cross sectional method. The research subjects were BPH patients at Ulin General Hospital, Banjarmasin who met the inclusion and exclusion criteria. The independent variable is Intravesical Prostatic Protrusion. The dependent variable is the results of the Uroflowmetry q max examination. Data analysis used Spearman's rank correlation test. The results showed that the average size of enlarged prostate was 8.623 ± 5.694 mm and the average q max uroflowmetry was 9.945 ± 4.238 ml/second. Conclusion In this study p = 0.029 indicating that there is an adequate correlation and has a negative relationship between Intravesical Prostatic Protrusion and q max uroflowmetry. The higher the Intravesical Prostatic Protrusion measurement, the lower the q max uroflowmetry.
HUBUNGAN ANTARA LAMA SIKLUS MENSTRUASI DAN KADAR GLUKOSA DARAH PADA MAHASISWA PSKPS ULM Anisa, Anisa; Huldani, Huldani; Biworo, Agung
Homeostasis Vol 7, No 1 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v7i1.12359

Abstract

Abstract: Menstrual cycle can affected blood glucose levels. Every woman has a different length of menstrual cycle, generally due to variations in the follicular phase of the cycle. In the follicular phase the hormone estrogen is higher than in the luteal phase. The hormone estrogen can increase insulin sensitivity and reduce levels of blood glucose. This research aims to explain the relationship between the length of the menstrual cycle and blood glucose levels in PSKPS ULM students class 2020-2022. This research use an analytical observational method with a cross sectional approach using purposive sampling techniques. Research subjects were asked to fill out a research question and answer sheet via Google form. There were 32 PSKPS ULM students who met the inclusion and exclusion criteria and had their blood glucose levels measured. Data analysis used the Spearman correlation statistical test. The results of data analysis showed that there was no significant relationship between the length of the menstrual cycle and blood glucose levels in PSKPS ULM students. (r=-0.091, p=0.622) Keywords: length of menstrual cycle, blood glucose, PSKPS ULM students. Abstrak: Siklus menstruasi dapat mempengaruhi kadar glukosa darah. Lama siklus menstruasi setiap wanita berbeda-beda, umumnya terjadi karena variasi pada fase folikuler siklus. Pada fase folikuler hormon estrogen lebih tinggi dibandingkan pada fase luteal. Hormon estrogen dapat membuat kadar glukosa darah meningkat karena pengaruhnya terhadap peningkatan sensitivitas insulin. Penelitian ini bertujuan menjelaskan hubungan antara lama siklus menstruasi dan kadar glukosa darah pada mahasiswa PSKPS ULM angkatan 2020-2022. Metode observasi analitik cross sectional digunakan dalam penelitian ini. Pemilihan subjek penelitian dengan menggunakan teknik purposive sampling Subjek penelitian diminta untuk mengisi lembar tanya jawab penelitian melalui google form. Terdapat 32 orang mahasiswa PSKPS ULM yang memenuhi kriteria inklusi dan eksklusi dan melakukan pengukuran kadar glukosa darah. Uji statistik korelasi Spearman’s digunakan untuk menganalisis data pada penelitian ini. Kesimpulan dari hasil analisis didapatkan bahwa tidak terdapat hubungan yang signifikan antara lama siklus menstruasi dan kadar glukosa darah pada mahasiswa PSKPS ULM.  (r=-0,091, p=0,622) Kata-kata kunci: lama siklus menstruasi, glukosa darah, mahasiswa PSKPS ULM
AKTIVITAS REPELEN EKSTRAK ETANOL DAUN SIRIH MERAH (Piper ornatum) TERHADAP NYAMUK Aedes aegypti Bangsawan, Bucek Ibrahim; Joharman, Joharman; Widyamala, Erida
Homeostasis Vol 7, No 2 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v7i2.13216

Abstract

Abstract: The red betel leaf (Piper ornatum) contains secondary metabolites such as flavonoids, alkaloids, and tannins, which hold potential as repellents. This study aims to examine the repellent activity of the red betel leaf extract (Piper ornatum) against Aedes aegypti mosquitoes. The research design is a true experimental post-test only with a control group, comprising six treatments: extract concentrations of 12.5%, 25%, 50%, and 100%, a negative control (aquadest), and a positive control (DEET 15%). Treatments are applied to the lower arm of the subjects and exposed to mosquitoes for 5 minutes at 0, 60, 120, 180, and 240 minutes. The Shapiro-Wilk and Levene's tests at minutes 0, 60, 120, and 240 showed that the data were not normally distributed and not homogeneous, while at minute 180, the data were normally distributed. Subsequently, the One-Way ANOVA and Kruskall Wallis tests resulted in a p-value of <0.05, suggesting significant differences among treatments. The research findings indicate that at a concentration of 100%, the red betel leaf extract exhibits a repellent efficacy of ≥90% at 0, 60, 120, and 180 minutes. Thus, the red betel leaf extract demonstrates repellent activity at each minute of testing. Keywords: Piper ornatum, red betel leaf, repellent, Aedes aegypti Abstrak: Sirih merah (Piper ornatum) memiliki metabolit sekunder seperti flavonoid, alkaloid, dan tanin yang berpotensi sebagai repelen. Tujuan penelitian ini untuk menganalisis aktivitas repelen ekstrak daun sirih merah (Piper ornatum) terhadap nyamuk Aedes aegypti. Desain penelitiannya adalah eksperimen dengan pascates saja dan kelompok kontrol dengan enam perlakuan yaitu konsentrasi ekstrak 12,5%, 25%, 50%, 100%, kontrol negatif (aquades), dan kontrol positif (DEET 15%). Perlakuan dioleskan pada lengan bawah probandus, dipaparkan selama 5 menit pada nyamuk dimenit ke-0, 60, 120, 180, dan 240. Pada Shapiro-Wilk dan Levene’s dimenit 0, 60, 120, 240 data tidak terdistribusi normal dan homogen, sedangkan menit ke-180 data terdistribusi normal.  kemudian pada One-Way ANOVA dan Kruskall Wallis didapatkan nilai p<0,05 yang disimpulkan terdapat perbedaan signifikan. Hasil penelitian menunjukkan pada konsentrasi 100% memiliki persentase daya tolak ≥90% dimenit pengujian dan ekstrak sirih merah memiliki aktivitas repelen di setiap menit pengujian. Kata-kata kunci: Repelen Piper ornatum, daun sirih merah, Aedes aegypti