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Mandala of Health : A Scientific Journal
Published by Universitas Jenderal Soedirman
ISSN : -     EISSN : 26156954     DOI : https://doi.org/10.20884/1.mandala
Core Subject : Health,
Dentistry Health Professions Public Health
Mandala of Health : A Scientific Journal is a medical scientific journal with open access published by the Faculty of Medicine, Jenderal Soedirman University, containing research articles, systematic reviews, and case reports in all areas of basic medical science, clinical medicine, biomedical science, medical biotechnology, and public health.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 140 Documents
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CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY: A COMPREHENSIVE REVIEW OF PATHOPHYSIOLOGY, CLINICAL MANIFESTATIONS AND MANAGEMENT STRATEGIES Aulia, Rashieka Salma; Indriawan, Ramses
Mandala Of Health Vol 18 No 2 (2025): Mandala of Health: A Scientific Journal
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mandala.2025.18.2.17802

Abstract

Chemotherapy-induced peripheral neuropathy (CIPN) is a side effect of chemotherapy that damages peripheral nerves, causing sensory, motor, and autonomic abnormalities that significantly decrease the quality of life for cancer patients. Characterized by symptoms such as numbness and tingling, the incidence of CIPN can reach 68% in the first month post-therapy. The severity of this condition often forces a dose reduction or discontinuation of chemotherapy, which can compromise the effectiveness of cancer treatment. Based on this literature review of the last 10 years, CIPN is a significant clinical challenge. Therefore, comprehensive clinical guidelines for its diagnosis, symptom management, and prevention are needed to optimize cancer therapy outcomes
THE EFFECT OF BABY MASSAGE WITH LAVENDER OIL ON QUALITY OF BABY SLEEP (AGE 6-12 MONTHS) IN MARUKANGAN VILLAGE, SANDARAN DISTRICT EAST KUTAI REGENCY Utari, Adinda Dewi; Sulistyorini, Chandra; Hadiningsih, Eka Frenty; Tripertiwi, Sucita
Mandala Of Health Vol 19 No 1 (2026): Mandala of Health: A Scientific Journal
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mandala.2026.19.1.15768

Abstract

Background: Sleep is a basic need of living things that is important for physical, emotional recovery, and strengthening the body. However, 33% of babies in the world are reported to experience sleep disorders that can affect their cognitive and physical development. One of the non-pharmacological interventions used to improve the quality of infant sleep is baby massage using lavender oil. Objective: This study aims to determine the effect of baby massage with lavender oil on improving the quality of sleep of infants aged 6-12 months in Marukangan Village, Sandaran District, East Kutai. Method: Quantitative research with a quasi-experimental research method using a pre-test and post-test with control group design, sampling using a purposive sampling method with a sample size of 52 infants divided into intervention and control groups. The intervention group was given massage therapy using lavender oil for 45 minutes, while the control group did not receive similar treatment. Data were analyzed using the Wilcoxon test. Results: The results showed a significant increase in the quality of infant sleep in the intervention group, infants experienced good sleep quality after being given therapy, namely with a p-value of 0.003 (p-value <0.05). In contrast, the control group showed a lower increase. This proves that baby massage with lavender oil is effective in improving the quality of baby sleep. Conclusion: Baby massage with lavender oil can be an effective complementary intervention to improve the quality of baby sleep. It is expected that this method can be applied by midwives and parents as a non-pharmacological solution to overcome baby sleep disorders.
ULTRASOUND GUIDED PERIPHERAL NERVE BLOCK FOR TRIGEMINAL NEURALGIA: A CASE REPORT Sulistyo, Bambang; Pramono, Wisnu Budi
Mandala Of Health Vol 19 No 1 (2026): Mandala of Health: A Scientific Journal
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mandala.2026.19.1.17754

Abstract

Background: Trigeminal neuralgia (TN), also known as tic douloureux, is a severe neuropathic pain disorder characterized by recurrent unilateral facial pain. Although pharmacological therapy remains the first-line treatment, a significant proportion of patients experience inadequate pain control or adverse effects. Alternative minimally invasive approaches are therefore needed. Case Presentation: A 26-year-old woman presented with a one-year history of severe, paroxysmal, electric shock-like pain on the left side of her face, with a Visual Analog Scale (VAS) score of 6. The pain was triggered by daily activities such as talking, eating, and brushing teeth. Clinical and laboratory examinations showed no abnormalities, and the patient was diagnosed with trigeminal neuralgia. Pharmacological treatment with paracetamol and pregabalin provided only temporary relief. The patient declined invasive procedures targeting the trigeminal ganglion. Intervention and Outcome: The patient underwent ultrasound-guided peripheral nerve block targeting the supraorbital, infraorbital, and mental nerves using lidocaine and dexamethasone. Immediately after the procedure, the patient reported complete pain relief (VAS score 0). At 7 days follow-up, the patient discontinued medication without recurrence of symptoms. At 3 months follow-up, the patient remained pain-free. Conclusion: Ultrasound-guided peripheral nerve block may serve as an effective and minimally invasive alternative for managing trigeminal neuralgia, particularly in patients who do not respond to pharmacological therapy or refuse more invasive procedures.
ANALYSIS OF THE IMPACT OF TRANSVERSUS ABDOMINIS PLANE BLOCK AND INTRATHECAL MORPHINE AS POST-CESAREAN Sulistyo, Bambang; Pramono, Wisnu Budi; Wahyudin, Wahyudin
Mandala Of Health Vol 19 No 1 (2026): Mandala of Health: A Scientific Journal
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mandala.2026.19.1.17755

Abstract

Background: Surgical wound pain 24 hours after cesarean section is still a problem found in obstetric patients. Many drugs are used to reduce pain scores both orally, intravenously, transdermally and others. However, it is necessary to pay attention to the dosage of the drug so that it does not harm the postoperative patient. Other methods that can be used include preoperative administration of intrathecal morphine and administration of transversus abdominis muscle blocks. Methods :The study's experimental design uses a post-test only control group. Three groups were created from 108 cesarean patients who had no problems. As per standard protocol, the control group (K) had a cesarean section with intravenous analgesia after the procedure. The Intrathecal Morphine (M) group got preoperative intrathecal morphine in addition to the same treatment as the K group. Apart from receiving the same treatment as group K, the Transversus Abdominis Plane Block (B) group also underwent bilateral transversus abdominis muscle blocks guided by ultrasonography. SPSS for Windows Release 26.0 was used to process the data, and differences with a significance level of 0.05 were examined using the One-Way ANOVA test analysis and the Bonferroni Post Hoc test. Outcomes: Group B differed significantly from group K on the visual analogue scale (p value = 0.000). Similar results were obtained for Group M compared to Group K (p value = 0.000). Group B and group M differ significantly from one another, as can be shown, Compared to group M, group B's visual analogue scale is lower (p=0.000). Conclusion: Intrathecal morphine and transversus abdominis block are effective in reducing post-cesarean section pain. Obtained a lower pain score in the administration of transversus abdominis block compared to intrathecal morphine with a significant difference.
SILENT TEARS BEHIND RECYCLED OBNOXIOUS TRADITIONAL WIDOWHOOD PRACTICES IN NIGERIA: AN INTERPRETIVE PHENOMENOLOGICAL ANALYSIS AKINDUYO, Tosin Emmanuel
Mandala Of Health Vol 19 No 1 (2026): Mandala of Health: A Scientific Journal
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mandala.2026.19.1.19193

Abstract

This study investigated the silent tears behind recycled obnoxious traditional widowhood practices in Nigeria. The age-long widowhood practices are embedded in trauma-laced traditional norms, negatively affecting the well-being of widows in Nigeria. This study adopted an Interpretative Phenomenological Analysis (IPA) qualitative design. Twenty-five (25) widows voluntarily participated in this study using snowball sampling techniques from different widows’ support groups. A semi-structured interview was used to obtain information from all participants. This enables widows to share their lived experiences of various traditional widowhood practices, which were regarded as obnoxious and dehumanizing to them. Data collection was conducted in seven (7) steps, using semi-structured interviews. It was concluded that recycled obnoxious traditional widowhood practices in Nigeria, as expressed by widows, are cruel treatments, financial constraints, loss of companions, disinheritance, sexual concerns, and assault/exploitation. It was recommended, among others, that, in line with Sustainable Development Goal 5, there should be a well-grounded legal framework that promotes gender equality, eradicates gender-based discrimination, and empowers all women.
COMPARISON OF RICERCA INDEX VALUES AS A SCREENING METHOD FOR BETA THALASSEMIA MINOR AND IRON DEFICIENCY ANEMIA AT PROF. DR. MARGONO SOEKARJO HOSPITAL Amadea, Talitha Daffa; Fitrianto, Agus; Lestari, Tri
Mandala Of Health Vol 19 No 1 (2026): Mandala of Health: A Scientific Journal
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mandala.2026.19.1.19477

Abstract

Beta thalassemia minor and iron deficiency anemia (IDA) are the most common causes of microcytic hypochromic anemia with similar laboratory features but require different management approaches, making differentiation between these two conditions often challenging. The Ricerca index is a simple screening method based on RDW and RBC parameters that can distinguish beta thalassemia minor from IDA. To analyze the optimal cut-off, sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and diagnostic accuracy of the Ricerca index in differentiating beta thalassemia minor from iron deficiency anemia at Prof. Dr. Margono Soekarjo Regional General Hospital. This was an analytical observational study with cross-sectional design using consecutive sampling from secondary data of medical records of patients aged ≤18 years during the 2020-2025 period, obtaining 40 subjects with beta thalassemia minor and 40 subjects with IDA. The Ricerca index value was calculated using the RDW/RBC formula. Diagnostic test analysis of the Ricerca index was performed using Receiver Operating Characteristic (ROC) curve. There were significant differences in the distribution of subject age, Hb and RBC values, and Ricerca index values between both groups (ρ<0.001). The optimal cut-off value of the Ricerca index was <4.3 for beta thalassemia minor and >4.3 for IDA. The Area Under the Curve (AUC) value was 0.861 (95% CI: 0.776-0.945; ρ<0.001). The sensitivity, specificity, PPV, and NPV of the Ricerca index for beta thalassemia minor were 77.50%, 80.00%, 79.49%, and 78.05%, respectively, while for IDA they were 80.00%, 77.50%, 78.05%, and 79.49%, with a Youden index of 0.58. The Ricerca index has good diagnostic performance with an accuracy of 86.1%, making it suitable for use as a screening method to differentiate beta thalassemia minor from IDA.
RISK FACTORS FOR PREECLAMPSIA INCIDENTS AT PROF. DR. MARGONO SOEKARJO HOSPITAL AUGUST 2023 – JULY 2024 Syahrinto, Keysa Putra; Wibowo, Yudhi; Priyanto, Edy; Sumawan, Herman; Muhaimin, Amalia
Mandala Of Health Vol 19 No 1 (2026): Mandala of Health: A Scientific Journal
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mandala.2026.19.1.19682

Abstract

Background: Preeclampsia is the leading cause of maternal death in Central Java in 2023. Preeclampsia is known to be associated with risk factors such as gemelli, maternal age, gravida, parity, diabetes mellitus (DM), and maternal nutritional status before pregnancy, although there are still differences in the relationship values ​​​​in several research center. Therefore, research is needed to determine the relationship of preeclampsia risk factors with the incidence of preeclampsia at RSUD Prof. Dr. Margono Soekarjo. Objective: This study aims to determine the relationship between maternal nutritional status before pregnancy, DM, maternal age, gravida, parity, and gemelli with the incidence of preeclampsia at RSUD Prof. Dr. Margono Soekarjo August 2023 – July 2024. Methodology: This study was conducted using a cross-sectional study design with a sample of 392 pregnant women. The independent variables in this study were gemelli, maternal age, gravida, parity, DM, and maternal nutritional status before pregnancy, the dependent variable was the diagnosis of preeclampsia, and the potential confounding variable controlled was bacteriuria. Results: The results of multivariate analysis showed that gemelli (p= 0.008), age <20 years (p= 0.009), age >35 years (p<0.001), overweight (p<0.001), obesity (p<0.001), chronic energy defficient (p<0.001), nulliparous (p<0.001), and multiparous or grandemultiparous (p<0.001) were significantly associated with the incidence of preeclampsia at RSUD Prof. Dr. Margono Soekarjo in August 2023 – July 2024. Conclusion: Gemelli were the risk factor that most influenced the incidence of preeclampsia at RSUD Prof. Dr. Margono Soekarjo in August 2023 – July 2024.
DIETARY HABITS AS INDEPENDENT PREDICTORS OF ANEMIA AMONG FEMALE ADOLESCENT STUDENTS AT SENIOR HIGH SCHOOL 1 AJIBARANG Khairunnisa, Difa Ifa; Hafiidhaturrahmah, Hafiidhaturrahmah; Lestari, Tri; Santosa, Qodri
Mandala Of Health Vol 19 No 1 (2026): Mandala of Health: A Scientific Journal
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mandala.2026.19.1.19847

Abstract

Anemia remains a major public health problem, affecting approximately 29.9% of adolescents globally. Dietary habits are a major modifiable risk factor; however, their role as an independent predictor in rural Southeast Asian settings is not yet fully documented. This study aimed to identify dietary habits and evaluate them as an independent predictor of anemia among female adolescents at Senior High School 1 Ajibarang, Central Java, Indonesia. A cross-sectional study was conducted involving 261 participants (aged 14–17 years) recruited through total sampling. Dietary habits were assessed using a semi-quantitative Food Frequency Questionnaire (FFQ), while anemia status was determined by hemoglobin levels measured via a Point of Care Testing (POCT) device. The prevalence of anemia was 41.0%, with 58.2% of respondents exhibiting poor dietary habits. Bivariate analysis showed a significant association between dietary habits and anemia (p = 0.027; OR = 1.777; 95% CI: 1.067–2.962). The multivariate logistic regression analysis, adjusted for age and socioeconomic confounders, revealed that dietary habits emerged as the sole independent predictor of anemia (p = 0.024). Respondents with poor dietary habits were 1.79 times more likely to be anemic compared to those with good habits (AOR = 1.793; 95% CI: 1.075–2.991). In conclusion, dietary habits are the primary independent predictor of anemia among female adolescents in this rural Indonesian setting.
THE INFLUENCE OF LEPROSY LITERACY ON COMMUNITY PARTICIPATION IN CONTROL AND ELIMINATION PROGRAMS Najia, Sofia; Hapsari, Yunita; Dilaga, Marisa Syavitri; Rizki, Mohammad
Mandala Of Health Vol 19 No 1 (2026): Mandala of Health: A Scientific Journal
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mandala.2026.19.1.19945

Abstract

Leprosy, or Morbus Hansen’s disease, remains a critical neglected tropical disease, with Indonesia consistently ranking among the top three global contributors, reporting up to 15,000 new cases annually. Despite national elimination efforts, high-endemic clusters persist with a high prevalence of multibacillary cases, which significantly increase the risk of complications and permanent disability. The primary challenge to effective control lies in low public awareness and pervasive social stigma, which lead to delayed diagnosis and the concealment of the disease. This study aims to analyze the relationship between leprosy literacy defined as the level of understanding regarding causes, symptoms, and transmission and community participation in elimination programs. Using a scoping review design based on the Arksey and O’Malley framework, a systematic search was conducted across five major databases for literature published between 2016 and 2026. The findings reveal that basic knowledge remains critically low due to entrenched traditional myths, though formal education, younger age, and direct interaction with health workers are significant predictors of higher literacy. Stigma is identified as the most substantial barrier to community engagement; however, culturally sensitive education and the involvement of local leaders have proven effective in increasing early case detection and treatment adherence. Ultimately, high leprosy literacy is a key determinant for mobilizing community resources and reducing psychological barriers to health-seeking behavior. The study concludes that literacy serves as the foundation for collective behavioral change. Integrating health communication strategies with local wisdom and digital platforms, supported by local government policy, is essential for fostering inclusive environments and achieving sustainable disease elimination and socio-economic recovery for affected individuals in Indonesia.
THE AVOIDANT PERSONALITY DISORDER AS A VULNERABILITY FACTOR IN MIXED ANXIETY AND DEPRESSIVE DISORDER: A CASE REPORT Sitopu, Jeanne Meilisa; Gracia, Elsy Emmily; Sinaga, Mirna Lidiya Yosefa
Mandala Of Health Vol 19 No 1 (2026): Mandala of Health: A Scientific Journal
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mandala.2026.19.1.19926

Abstract

Background: The prevalence of Avoidant Personality Disorder has been estimated at approximately 3.3%, with one study reporting a lifetime prevalence of 9.3% among women older than 25 years. Avoidant Personality Disorder is an enduring personality pattern characterized by social avoidance, feelings of inadequacy, and hypersensitivity to negative evaluation. These characteristics may function as psychological vulnerability factors for affective psychopathology, particularly Mixed Anxiety and Depressive Disorder. Methods: This study employed a qualitative descriptive case report approach. Data were obtained through comprehensive psychiatric history-taking, mental status examination, clinical observation, and psychometric assessment using the Hamilton Anxiety Rating Scale (HARS), Hamilton Depression Rating Scale (HDRS), Minnesota Multiphasic Personality Inventory-2 (MMPI-2), and Millon Clinical Multiaxial Inventory-IV (MCMI-IV). Diagnosis was established in accordance with the Indonesian Classification and Diagnostic Guidelines for Mental Disorders, Third Edition (PPDGJ III). Results: Mrs. RM, a 29-year-old woman, presented with complaints of anxiety, marked difficulty engaging in social interactions due to fear of rejection, impaired concentration, and difficulty initiating sleep, accompanied by palpitations, tremulousness, and cold extremities for the preceding three months. The patient experienced significant psychosocial stressors, including family dysfunction and marital relationship difficulties, which were exacerbated by underlying avoidant personality disorder pathology. Psychometric evaluation revealed moderate anxiety and depressive symptoms, while personality assessment demonstrated a persistent avoidant personality pattern. The patient was diagnosed with Mixed Anxiety and Depressive Disorder with comorbid Avoidant Personality Disorder. Clinical improvement was observed following treatment with fluoxetine 20 mg once daily, clobazam 10 mg once daily, supportive psychotherapy, and Cognitive Behavioral Therapy (CBT). Conclusion: Avoidant Personality Disorder served as a major vulnerability factor and enduring personality pattern contributing to the development and persistence of Mixed Anxiety and Depressive Disorder, thereby prolonging and complicating the therapeutic course. Appropriate psychotherapeutic intervention, particularly CBT, is therefore essential in the management of such cases.

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