cover
Contact Name
I Wayan Sudarsa
Contact Email
sudarsa@unud.ac.id
Phone
-
Journal Mail Official
globalpharmatechnology@gmail.com
Editorial Address
India
Location
Kota denpasar,
Bali
INDONESIA
Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 2,439 Documents
Dominating Energy in products of intuitionistic fuzzy graphs Shaik Sharief Basha; A kalimulla; R Vijayaragavan
Journal of Global Pharma Technology .
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The concept of energy of an Intuitionistic Fuzzy Graph is extended to dominating Energy in various products in Intuitionistic Fuzzy Graph. In this paper, We have obtained the value of dominating Energy in different products such as ring Sum, Cartesian Product, Lexicographic Product, Tensor product  and Strong Product between two intuitionistic Fuzzy graphs. Also we study the relation between the dominating Energy in the various products in two Intuitionistic Fuzzy Graphs.
Emerging Developmental Genetic Model Platform in Holometabolous Insects Rehal Jehad Husain
Journal of Global Pharma Technology Volume 11 Issue 01.
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The wide variety on grasshopper kind up to expectation is bent according to practical genetic studies is thriving rapidly then affords much instant research possibilities between developmental yet evolutionary biology. Nanotechnology is an interdisciplinary research field. The holometabolous bugs characterize a disproportionate percentage regarding brute diversity yet are for that reason well positioned after grant model species because of a large variety of developmental processes. Here we discuss emerging holometabolous fashions or review some recent breakthroughs. Nanoparticle-mediated cloth shipping according to flora then superior biosensors because of directness farming are viable only through nanoparticles yet Nano chips. Nano encapsulated conventional fertilizers, pesticides, and herbicides help within the gradual and sustained launch about nutrients yet agrochemicals ensuing of the precise degree to the plants. Nanotechnology-based drive into viral disease detection kits are also turning into popular and are useful of fast then promptly detection of viral diseases. In that article, the strong usage or benefits regarding nanotechnology between directness agriculture are discussed. The contemporary nanotechnology-based equipment yet techniques hold the potent in accordance with address the variety of problems regarding conventional agriculture then can revolutionize this sector.
Saccharomyces cerevisiae Immobilisation in Sodium Alginate for Red Dragon Fruit Winemaking N. P. Minh
Journal of Global Pharma Technology Volume 11 Issue 08 (2019) Aug. 2019
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Red dragon fruit is rich in sugar, organic acids and minerals and other nutrients. It has good processing properties; it is used in the production of fruit juice, jam, and preserved fruit. Its economic value in local market is quite low. Making wine is not only converting the fruit into wine, but also improves its economic value of dragon fruit. Objective of this study focused on the effect of encapsulation of Saccharomyces cerevisiae in sodium alginate complexed with calcium chloride in red dragon fruit wine fermentation. Different technical parameters such as sodium alginate concentration (2.0%, 4.0%, 6.0%, 8.0%, 10%), bead size (2mm, 4mm, 6mm, 8mm, 10mm), bead loading (5 g/100ml, 10 g/ 100ml, 15 g/100ml, 20 g/ 100ml, 25 g/ 100ml), initial total soluble solid (10, 12, 14, 16, 18oBrix), clarifying agent (gelatin, bentonite, wheat gluten, egg white, kieselsol and kaolin) in wine making. Results showed that the best wine quality based on ethanol content (19.38%v/v) and sensory score were recorded by encapsulation of Saccharomyces cerevisiae in 6% sodium alginate, bead size 6mm, bead loading 20 g/ 100ml, initial soluble solid 16%, gelatin as clarifying agent.Keywords: Dragon fruit, Sodium alginate, Calcium chloride, Saccharomyces cerevisiae, Encapsulation, gelatin, Wine.
DNA METHYLATION IN THYROID-STIMULATING HORMONE GENE: PREDICTOR OF GRAVE’S DISEASE RECURRENCE IN INDONESIA Luluk yunaini; Dwi Anita Suryandari; Trisia Lusiana Amir; Dwi Yanti; Fatimah Eliana
Journal of Global Pharma Technology Volume 10 Issue 06: (2018) June 2018
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Thyroid-stimulating hormone receptor (TSHR) has a critical role in Graves’ disease (GD). GD is an autoimmune disease which is multifactorial. Environmental factors can affect the epigenetic, a changes in gene expression without any changes in base sequence of the DNA. One of the epigenetic types is methylation. This study aims to determine the status of DNA methylation in TSHR gene in patients with GD to be one of the predictors of recurrence. This study used a case control design with 58 samples of GD patients divided into 29 groups of recurrence and 29 groups of non-recurrence. DNA methylation examination used methylation-specific PCR (MSP) method. Our result found that DNA methylation profile of GD in Indonesia were 5% with complete DNA methylation, 17% complete DNA unmethylation and 78 partial DNA methylation. Statistical analysis showed no significant different between recurrence and non-recurrence group (p>0.05). Nevertheless, our result showed no patient with complete status DNA methylation was found in recurrence group. This shows that in recurrence occur a reduction of DNA methylation resulting in increasing of TSHR production. Thus, DNA methylation in TSHR gene might be has a role in the risk of recurrence GD.
Evaluation and Comparison the Antibacterial Activity of Silver Nano Particles (AgNPs) and Silver Nitrate (AgNO3) on Some Pathogenic Bacteria Halah Dawood Salman
Journal of Global Pharma Technology Volume 9 Issue 10
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Resistance of bacteria to some antibiotics increased tremendously therefore demanding for solutions and new medicine becomes essential as this problem related to human health. For this purpose, using of nanoparticles increased rapidly during the last years. In this study, the effect of silver nanoparticles (AgNPs) and silver nitrate (AgNO3) on bacteria had been evaluated and compared.  Commercial purchased silver nanoparticles (with the particles size 20nm and Scanning Electron Microscopy (SEM) image) were characterized by X-ray diffraction (XRD). Antimicrobial activity of nanoparticles Silver and  silver nitrate were evaluated on some pathogenic bacteria including  samples  including: Streptococcus pyogenes  and Staphylococcus aureus (Gram Positive Bacteria)and Escherichia coli , Klebsiella pneumonia, Salmonella  typhi, Acine to bacter baumannii  and Vibrio cholerae   (Gram Negative Bacteria).In this research,  antibacterial activity for nanoparticle silver and silver nitrate at different concentrations started from 10 to 150μg ml−1against bacterial isolates was measured by agar diffusion technique and Minimum Inhibitory Concentration (MIC)/ Minimum bactericidal Concentration (MBC).These pathogens caused different hazardous infections and some of these bacteria are multi-drug resistant, the results exhibited  remarkable antibacterial activity of silver nanoparticles (AgNPs) compared to moderate effect of silver nitrate (AgNo3) against most tested isolates including serious Gram Negative Bacteria resistant bacteria K.pneumonia , S.  typhi and V. cholerae , the exception was A. baumannii as these bacteria didn’t affected definitely by any concentrations of Ag NPs or AgNo3 in the detection tests  of  MIC and MBC.  Keywords: Silver Nan particles, Silver Nitrate, Pathogenic Bacteria
Differential-Pulse Polarography Method for Evaluation of Diclofenac Sodium in Pharmaceuticals Heba Y. Ahmed
Journal of Global Pharma Technology Volume 10 Issue 10: 2018
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

A reliable DPP process has been developed and applied for the estimation of Diclofenac sodium in pharmaceuticals form with DME versus Ag/AgCl. The best peak response was established a cathodic peak -1.14V in 0.002 M acetate buffer at pH5and 0.1M KCl as supporting electrolyte with four electrons transferred in irreversible process. To attain the highest sensitivity, instrumental and experimental and parameters were examined including the type and concentration of supporting electrolyte, pH, buffer solutions, pulse amplitude, and voltage step time. Diffusion current was in direct proportion to Diclofenac sodium concentration and with a linear relationship with the drug concentration in the range of (5 - 30 μg. mL-1) i.e. (1.57 × 10-5-9.4× 10-5 mol·L–1) with a correlation coefficient (r= 0.9993), detection limit (S/N = 3) was 0.85 μg. mL-1(i.e.2.67 × 10-6 mol·L–1) and the values of precision, in terms of RSD% ranged between 1.28- 4.11%.The established DPP methods offers excellent analytical figures of merits as well as applied to examine the commercial drug olfen capsule and Diclofenac sodium injection for the determination of Diclofenac sodium and found to be 99.8 mg, 76.9 mg compared to the stated value of 100mg and 75 mg respectively.Keywords: Differential-pulse polarography; Diclofenac sodium.
Effects of Binahong (Anredera Cordifolia) Leaf Ethanol Extracts on Blood Glucose Levels and Pancreas Histopathology in Hyperglycemic Rats Sri Wahjuni
Journal of Global Pharma Technology Volume 11 Issue 04.
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: The use of binahong leaf has been carried out for medical purposes for centuries. Severalstudies have shown that binahong contain alkaloids, saponins, tannins, glycosides, and terpenes,which can be known to have effects to reduce blood sugar levels. Objective: This study to determinethe effect of binahong leaf ethanol extract in reducing blood glucose and histopathological change inhyperglycemic rats. Method: This study was an experimental study using Wistar rats that weredivided into five groups. The normal group was given with distilled water (P0), the positive controlgroup received glibenclamide (P1), and intervention group was given orally binahong leaf extract ofethanol with a dose of 10mg/kg (P2), 15 mg/kg (P3) and 20 mg/kg (P4). Blood sugar level wasevaluated from the initial day of measurement to two weeks. Pancreas tissue was obtained toevaluate the histopathological change. Results: Mean blood sugar level in each group respectively94.28±6.19 mg/dL, 133.61±47.05 mg/dL, 117.56±26.73 mg/dL, 124.77±37.05 mg/dL, and 136.57±47.55mg/dL. The result of Kruskal-Wallis test was p=0.011. Multiple comparison test showed significantresult between P4 with P0 (p=0.011). Conclusion: Binahong leaf ethanol extract with a dose of 20mg/kg significantly reduce blood glucose level in the hyperglycemic rat.Keywords: Binahong, Anredera cordifolia, Blood glucose, Hyperglycemic rat.
The Implementation of Ergo-Learning 2.0 Strategy in Reducing Fatigue and Improving Speed, Thoroughness and Constancy of Vocational School Students in Semarapura City, Bali I Wayan Sudiarsa
Journal of Global Pharma Technology Volume 12 Issue 02 (2020) Feb. 2020
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The ergo-learning strategy 2.0 is a combination between e-learning 2.0 and the principles of ergonomics, so that a humanistic learning process can be generated. This learning strategy was implemented in the form of improving the redesign of the classroom, lighting arrangements, learning media, active break, and stretching using Systemic-Holistic-Interdisciplinary-Participatory (SHIP Approach). This study was an experimental study, conducted using a Randomized Pre- and Post-test Control Group Design. Each group (control and treatment) consisted of 12 people. General fatigue data were collected using a 30 items of rating scale questionnaire with a Likert scale, while speed, thoroughness and constancy data were collected using the Bourdon Wiersma test. The results showed that the ergo-learning strategy 2.0 could reduce fatigue as seen from a decrease in general fatigue by 28.09%, an increase in student speed by 65.91%, an increase in student thoroughness by 50.88% and an increase in student constancy by 48.11%. It is recommended to teachers to implement the ergo-learning 2.0 strategy in learning and to policy makers in schools to consider applying the principles of ergonomics in the management of Education.Keywords: Ergo-Learning 2.0, fatigue, Speed, Thoroughness, Constancy, Ergonomics.
In-vitro Study of Layer Double Hydroxide Nanoparticles as Effective Carrier to Fight Breast Cancer Growth Mohammed S. K. Albermani
Journal of Global Pharma Technology .
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Vinblastine is well known alkaloid chemotherapy to treat various types of cancer including breast cancer, merging the field of nanotechnology and therapeutic drugs have brought a great interest. However nanodrugs delivery system has been given great attention in this field especially cancer-drug delivery system due to its significant properties which can be increased drug loading, reduced side effect of the drug and suppress cancer proliferation. Layers of magnesium and aluminum layered double hydroxide nanoparticles (LDH) have been synthesized by co-precipitation method with 25 to 50 nm size as SEM has revealed. Vinblastines have been intercalated in to LDH by ion exchange. Breast cancer cell line  MCF-7 have been  used to determine the cytotoxicity of Vin-NPs via MTT survival assay at different time interval 24 hrs, 48 hrs and 72 hrs. Cell viability of MCF-7 through MTT assay suggests drug intercalated LDHs has better drug delivery vehicle for cancer cell line against poor bioavailability of the pure Vinblastine. These observations clearly demonstrate that Vinblastine intercalated LDH NPs is a potential drug delivery vehicle for anticancer drugs which can increase drug efficiency , reduce the side effects and reduce the cost of the drug as well.Keywords:  LDH nanoparticles, Vinblastine sulfate, MCF-7 cell line and MTT assay.
Depression Prevalence Among Students of Jahrom University of Medical Sciences navid kalani
Journal of Global Pharma Technology Volume 08 Issue 06
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Depression has been known as one of four leading disorders and one of most prevalent disabilities throughout the world. Due to their close involvement with and responsibility for patients’ health and, students of different fields related to medical sciences are more liable to be exposed with depression. This investigation is aimed to explore the prevalence of depression among medical students of Jahrom University of Medical Sciences through 2013-2014. Methods & Materials: This study was a cross-sectional and descriptive study done on360 students of Jahrom University of Medical Sciences during 2013-2014. Data were obtained by Beck depression test and analyzed by SPSS software version 15.   Results:Results associated with the prevalence of depression in medical studentsin terms of the severity showed that 47 students (13.1%) had moderate depression and 32 students (18.9%) had severe depression. Fisher's accurate testdid not reveal any statically differences betweenfamily history of the disorder with depression disorder of students (P=0.21). Conclusion: In accordance to our finding, a number of policies should be taken into account to reduce factors conducive to depression and prevent its consequences through quick and timely diagnosis. Keywords: Depression, students of Medical Sciences, Beck depression test, prevalence.

Page 89 of 244 | Total Record : 2439


Filter by Year

2010 2026


Filter By Issues
All Issue Volume 18 Issue 01 (2026) Jan. 2026 Volume 17 Issue 12 (2025) Dec. 2025 Volume 17 Issue 11 (2025) Nov.2025 Volume 17 Issue 10 (2025) Oct. 2025 Volume 17 Issue 04 (2025) April 2025 Volume 17 Issue 03 (2025) March 2025 Volume 17 Issue 02 (2025) Feb. 2025 Volume 17 Issue 01 (2025) Jan 2025 Volume 16 Issue 12 (2024) Dec. 2024 Volume 16 Issue 11 (2024) November 2024 Volume 16 Issue 10 (2024) October 2024 Volume 16 Issue 09 (2024) September 2024 Volume 16 Issue 08 (2024) August 2024 Volume 16 Issue 07 (2024) July 2024 Volume 16 Issue 06 (2024) June 2024 Volume 16 Issue 05 (2024) May 2024 Volume 16 Issue 04 (2024) April 2024 Volume 16 Issue 03 (2024) March 2024 Volume 16 Issue 02 (2024) February 2024 Volume 16 Issue 01 (2024) January 2024 Volume 14 Issue 05 (2022) May 2022 Volume 13 Issue 05 (2021) May 2021 Volume 13 Issue 04 (2021) April 2021 Volume 13 Issue 03 (2021) March 2021 Volume 13 Issue 02 (2021) Feb. 2021 Volume 13 Issue 01 (2021) Jan. 2021 Volume 12 Issue 12 (2020) Dec. 2020 Volume 12 Issue 11 (2020) Nov. 2020 Volume 12 Issue 10 (2020) Oct. 2020 Volume 12 Issue 09 (2020) Sept. 2020 Volume 12 Issue 08 (2020) Aug. 2020 Volume 12 Issue 07 (2020) July 2020 Volume 12 Issue 06 (2020) June 2020 Volume 12 Issue 05 (2020) May 2020 Volume 12 Issue 04 (2020) April 2020 Volume 12 Issue 03 (2020) March 2020 Volume 12 Issue 02 (2020) Feb. 2020 Volume 12 Issue 01 (2020) Jan. 2020 Volume 12 Issue 08 Volume 11 Issue 12 (2019) December 2019 Volume 11 Issue 11 (2019) November 2019 Volume 11 Issue 10 (2019) October 2019 Volume 11 Issue 09 (2019) September 2019 Volume 11 Issue 09: (2019) September 2019 Volume 11 Issue 08 (2019) Aug. 2019 Volume 11 Issue 07 (2019) July 2019 Volume 11 Issue 06 (2019) June 2019 Volume 11 Issue 05 (2019) May 2019 Volume 11 Issue 04 (2019) April 2019 Volume 11 Issue 03 (2019) March. 2019 Volume 11 Issue 02 (2019) Feb. 2019 Volume 11 Issue 01 (2019) Jan. 2019 Volume 11 Issue 2: 2019 Volume 10 Issue 12. Volume 11 Issue 6. Volume 10 Issue 12 (2018) December 2018 Volume 10 Issue 11 (2018) November 2018 Volume 10 Issue 10 (2018) October 2018 Volume 10 Issue 09: (2018) September 2018 Volume 10 Issue 08: (2018) August 2018 Volume 10 Issue 07: (2018) July 2018 Volume 10 Issue 06: (2018) June 2018 Volume 10 Issue 05: (2018) May2018 Volume 10 Issue 04: (2018) April 2018 Volume 10 Issue 02: (2018) Feb 2018 Volume 10 Issue 01: (2018) Jan. 2018 Volume 10 Issue 10: 2018 Volume 10 Issue 01 Volume 09 Issue 12 Volume 09 Issue 11 Volume 9 Issue 11 . Vol. 9 Issue 7 : 2017 Volume 9 Issue 10 Volume 09 Issue 09 Volume 09 Issue 08 Volume 9 Issue 07 Volume 09 Issue 05 Volume 09 Issue 04 Volume 09 Issue 03 Volume 09 Issue 02 Volume 08 Issue 11 Volume 08 Issue 07 Volume 08 Issue 06 Volume 08 Issue 05 Volume 08 Issue 04 Volume 08 Issue 03 Volume 08 Issue 02 Volume 08 Issue 01 Volume. 9 Issue 6 Volume 08 Issue 10: (2016) October 2016 Volume 08 Issue 09: (2016) September 2016 Volume 12 Issue 01 Volume 11 Issue 07 Volume 11 Issue 05. Volume 11 Issue 04. Volume 11 Issue 03 Volume 11 Issue 01. Volume 08 Issue 08 Volume 04 Issue 02: (2012) February 2012 Volume 03 Issue 06: (2011) June 2011 Volume 03 Issue 04: (2011) April 2011 Volume 02 Issue 10: (2010) Oct.2010 Volume 02 Issue 07: (2010) July 2010 Volume 02 Issue 05: (2010) May 2010 Volume 02 Issue 03: (2010) March 2010 More Issue