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PharmaCine : Journal of Pharmacy, Medical and Health Science
Published by Universitas Singaperbangsa Karawang
ISSN : 27464199     EISSN : 27464199     DOI : https://doi.org/10.35706/pc.v3i2.8034
Core Subject : Humanities, Health, Science,
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health
PharmaCine: Journal of Pharmacy, Medical and Health Science merupakah media untuk publikasi ilmiah mengenai aspek farmasi, medis dan kesehatan. PharmaCine diterbitkan 2 kali dalam setahun sebagai wadah untuk mahasiswa, farmasis, tenaga medis dan tenaga kesehatan lainnya dalam update keilmuan dan bahan literatur ilmiah. PharmaCine mempublikasikan artikel meta analisis, artikel penelitian, artikel review, dan laporan kasus. Artikel yang masuk diperiksa oleh mitra bestari (peer-reviewed) yang sesuai dengan bidang keilmuannya. Ruang Lingkup: Ruang lingkup Jurnal PharmaCine meliputi aspek farmasi, medis dan kesehatan dengan topik sebagai berikut: Farmakologi, Farmakoterapi, Farmasi Klinik, Teknologi Farmasi, Farmasi Herbal, Farmasi Sosial , Manajemen Farmasi, Biokimia Klinik, Farmakogenetik, Kimia Farmasi, Biologi Farmasi, Ilmu Kesehatan Masyarakat (Public Health)
Arjuna Subject : Profesi Kesehatan - Farmasi
Articles 63 Documents
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Gambaran Kadar Albumin pada Penderita Diabetes Melitus Tipe II di RSUD H. A. Sulthan Daeng Radja Kabupaten Bulukumba Putri, Jusnita; Ridwan, Asriyani; Asdinar, Asdinar
PharmaCine : Journal of Pharmacy, Medical and Health Science Vol 5 No 1 (2024): PharmaCine: Journal of Pharmacy, Medical and Health Science
Publisher : Bachelor of Pharmacy Study Program, Faculty of Health Sciences, Universitas Singaperbangsa Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35706/pc.v5i1.10557

Abstract

Background: Type II diabetes mellitus is a metabolic disorder characterized by insulin resistance. Where this diabetic state affects plasma protein metabolism in the body, one of which is albumin. The occurrence of a decrease or increase in albumin levels is strongly influenced by several things including protein intake, alcohol, osmotic pressure, hormones and physiological factors.  Objective: to know the picture of albumin levels in patients with type II diabetes mellitus at H. A. Sulthan Daeng Radja Hospital, Bulukumba Regency. Method: this is a descriptive research with a cross sectional approach. Results: Showed that out of 28 patients, there were 7 people with low albumin levels and 21 people with normal albumin levels. The antioxidant potential of albumin shows that it is associated with diabetes mellitus. Theoretically, uncontrolled diabetes mellitus patients have low albumin levels Based on gender, respondents were male with low albumin levels as many as 3 people (43%) and female as many as 4 people (57%). Based on age where the percentage in the age range of 30-50 years as many as 13 people (46%), for ages 51-65 years as many as 12 people (43%), and ages 66-75 years as many as 3 people (11%). Conclusion: Obtained at low albumin levels in patients with type II diabetes mellitus who are female as many as 4 people (57%) and male sex as many as 3 people (43%). Keywords:  Diabetes mellitus, hypoalbuminemia, serum albumin levels
Pengembangan Potensi Konsentrat Buah Pare (Momordica charantia L.) sebagai Pencegahan Hiperkolesterol pada Mencit Jantan (Mus musculus) Sulistyaningtyas, Farah; Oktraiani, Zestyla
PharmaCine : Journal of Pharmacy, Medical and Health Science Vol 5 No 1 (2024): PharmaCine: Journal of Pharmacy, Medical and Health Science
Publisher : Bachelor of Pharmacy Study Program, Faculty of Health Sciences, Universitas Singaperbangsa Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35706/pc.v5i1.10913

Abstract

Background: Hypercholesterolemia is a condition characterized by an increase in cholesterol levels in the blood above the normal limit. Parsley contains some phytochemicals such as niacin, vitamin C, vitamin E, flavonoids, and saponins that are believed to lower blood cholesterol levels. This study aimed to determine the anti-cholesterolemia activity and dose concentration of ethanol concentrate steam in male rat scratches to prevent hypercholesterolemia. Pre-test and post-test research design using random sampling techniques. Animal trials used used twenty-five pairs of scissors, divided into five groups. One control group was given a standard diet and 0.2 ml NaCMC suspension, and four treatment groups were given additional oral treatment with standard diets and a dose of 0.02 ml suspension. Simvastatin, an ethanol concentrate of pear fruit, is given in doses of 0.5 ml/day, 1 ml/day, and 1.5 ml/day for 7 days—total cholesterol analysis using a cholesterol strip. The data obtained were analyzed using the ANOVA one-way test in SPSS 23. The administration of simvastatin and ethanol concentrate in the treatment group decreased total cholesterol levels compared to controls at all doses. The third dose concentration was ethanol concentrate of the fruit, with a dose of 1.5 ml/day, because it lowered the overall cholesterol level compared with the control group, treatment 2, and treatment 3. Based on the table of the one-directional ANOVA test, the results were achieved when the probability value (p) = 0,000 or the value (P) < 0,05. The resulting conclusion was that there was an average significant difference between normal cholesterol, high fat, and post-treatment. Keywords:  Cholesterol, Hypercholesterolemia, Simvastatin, Ethanol concentrate of bitter melon (Momordica charantia L)
Gambaran Kadar Kreatinin Darah pada Penderita Jantung Koroner Berdasarkan Jenis Kelamin Metode Jaffe Reaction di RSUD H.A Sulthan Daeng Radja Kab. Bulukumba Tahun 2022 Nurfadilah, Lely; Arwie, Dzikra; Muriyati, Muriyati
PharmaCine : Journal of Pharmacy, Medical and Health Science Vol 5 No 1 (2024): PharmaCine: Journal of Pharmacy, Medical and Health Science
Publisher : Bachelor of Pharmacy Study Program, Faculty of Health Sciences, Universitas Singaperbangsa Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35706/pc.v5i1.11000

Abstract

Background: Coronary0heart0disease is a condition in which the arteries experience narrowing due to the accumulation of fat on the artery walls. Creatinine is the end product of creatinine metabolism. High or low blood creatinine levels are used0as0an important0indicator to find out whether0a person0has impaired-kidney function, because blood creatinine examination can be used as an indicator of the development of coronary heart disease which can cause kidney failure in a person. The Jaffe Reaction is the reaction between creatinine and picric acid in alkaline conditions to form an orange yellow compound which is measured using a spectrophotometer. Aim: To determine the description of blood creatinine0levels in0patients with0coronary0heart0disease based on the gender of the jaffe reaction method at H. A Sulthan0Daeng Radja0Hospital, Kab.0Bulukumba. Method: This research is a quantitative research with a cross-sectional descriptive design. The sample of this study were coronary heart patients at H. A Sulthan Daeng Radja Hospital, Kab. Bulukumba in August 2022, with a total of 42 sufferers. Result: The results obtained from 42 samples of blood creatinine levels increased in coronary heart disease patients, 7 men (54%) and 6 women (46%) with a total increase of 13 people. While normal creatinine levels in coronary heart patients were 16 men (55%) and 13 women (45%) with a normal total of 29 people. Conclusion: Based on the sex characteristics of coronary heart patients, it is known that out of a total of 42, 22 people were male, and 20 were female. Meanwhile, based on the age characteristics of the research subjects, there were 10 young people aged 35-50, 19 people 51-65, 11 people aged 66-75, 76-85 2 people. Based on examination of blood creatinine levels of 42 patients with coronary heart disease, there were 13 people who had increased blood creatinine levels, where a higher increase occurred in men, 7 people had blood creatinine levels (> 0.7-1.3 mg/dl). Meanwhile, 6 women had increased blood creatinine levels (>0.6-1.1 mg/dl). Keywords:  Coronary heart disease, blood creatinine levels
Kasus Temuan Produk Obat dan Makanan Ilegal Yang Dijual Melalui E-Commerce dan Korelasinya dengan Peraturan Badan Pengawas Obat dan Makanan Nomor 8 Tahun 2020 Hanum, Nissa; Nafisa, Siti; Rohmah, Siti; Nihan , Yumareta Anggun; Ariyanto, Elvira Julia
PharmaCine : Journal of Pharmacy, Medical and Health Science Vol 5 No 1 (2024): PharmaCine: Journal of Pharmacy, Medical and Health Science
Publisher : Bachelor of Pharmacy Study Program, Faculty of Health Sciences, Universitas Singaperbangsa Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35706/pc.v5i1.11066

Abstract

Background: The advancement of information and communication technology has led society to rely on the use of communication devices and the internet. The global increase in e-commerce, coupled with the growth of digital health services, provides direct access to healthcare for patients, as well as globalization of production and distribution of medications. However, it is important to note that these activities can become illegal if e-commerce actors or involved institutions lack the necessary business permits and fail to comply with certification, licensing, registration, and other legal requirements. Aim: This article explores findings of illegal drug products within the context of online drug circulation through e-commerce. Method: The approach employed in this research is qualitative, utilizing descriptive analysis methods and data collection techniques through literature review. Result: It has been revealed that the sale of illegal drugs online occurs on the Marketplace through accounts using official pharmacy names. The illegal drugs and food products discovered do not adhere to good manufacturing standards and have unknown dosages. This poses a serious risk to public health if consumed. The identified types of illegal products include drugs specifically for men, illegal weight loss products, fake health supplements, illegal cosmetics, and counterfeit processed foods. Conclusion: The misuse of e-commerce platforms for the sale of illegal products must be taken seriously to safeguard the health and overall safety of the public. Keywords:  Illegal drugs, Online distribution, Supervision, Prevention, Legality
Deteksi Dini HIV (Human Immunodefeciency Virus) Menggunakan Metode Immunochromatography pada Remaja di Desa Bonto Bulaeng Tiana, Kasratul; Aryandi, Rahmat; Muriyati , Muriyati
PharmaCine : Journal of Pharmacy, Medical and Health Science Vol 4 No 2 (2023): PharmaCine: Journal of Pharmacy, Medical and Health Science
Publisher : Bachelor of Pharmacy Study Program, Faculty of Health Sciences, Universitas Singaperbangsa Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35706/pc.v4i2.11086

Abstract

Background: Human immunodeficiency virus (HIV) is a virus that weakens the human immune system, making people with the virus unable to fight various diseases that attack their bodies. Di sisi lain, Acquired Immunodeficiency Syndromes (AIDS) are symptoms that result from HIV infection that weakens the human immune system. Symptoms resulting from a weakening of the Human Immune System caused by HIV infection. The causes of Human Immunodeficiency Virus (HIV) are sexual intercourse, use of non-sterile syringes among drug users, use of piercings or tattoos, blood transfusions containing the HIV virus. Aim: The aim of the research is to determine the results of early detection of HIV (Human Immunodeficiency Virus) using the immunochromatography method in adolescents in BontoBulaeng Village. Method: This research method is descriptive research. This research was preceded by administering a questionnaire to obtain criteria in accordance with the research, HIV testing was carried out on adolescents using the immunochromatography method. This research began by giving questionnaires to respondents to obtain criteria that were appropriate to the research. Data analysis in this study used the SPSS frequency descriptive statistical test. Result: The results of this research were HIV tests on 30 teenagers, negative results were obtained (100%). Conclusion: Early detection of HIV using the immunochromatography method in adolescents in Bonto Bulaeng Village showed negative results for 30 samples (100%). Keywords: HIV, Teenager, Immunochromatografi
Pengaruh Sumber Asam Basa terhadap Sifat Fisik dalam Formulasi Granul Effervescent : Tinjauan Pustaka Pratama, Reza; Hasanah, Ida; Nurasih, Widya; Sagita, Novaliana Devianti
PharmaCine : Journal of Pharmacy, Medical and Health Science Vol 5 No 1 (2024): PharmaCine: Journal of Pharmacy, Medical and Health Science
Publisher : Bachelor of Pharmacy Study Program, Faculty of Health Sciences, Universitas Singaperbangsa Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35706/pc.v5i1.11229

Abstract

Background: Indonesia has abundant natural resources, including types of herbal plants. Herbal plants in Indonesia have various health benefits and have been widely processed in the form of functional drinks. Aim:. To reduce the often undesirable taste and odor characteristics of herbal medicine, it can be further processed into derivative products that taste good and have a longer shelf life. One way is to process it into an effervescent preparation. Method: Searching and collecting journal information is carried out electronically, namely by accessing international and national journal search sites such as online from Pubmed, Google Scholar and Sciencedirect. by using the keywords "Effervescent Granules" and "Effervescent Herbal Drinks". Result: In effervescent granules there are acids and bases, the acids used are citric acid and tartaric acid which are acid components commonly used in effervescent granules. The use of a single acid will cause difficulties in its manufacture. The combination of citric acid and tartaric acid in effervescent granule preparations aims to simplify the process of making effervescent granule formulations. Conclusion: The results of existing literature studies show that the combination of acids in effervescent preparations greatly facilitates the process of forming effervescent granules. The use of different combinations of acid sources affects the physical properties of effervescent granules, including flow rate, dissolution time, pH and others. Sodium bicarbonate as a base source has the most significant influence on water content. The acid combination commonly used in making effervescent granules is citric acid and tartaric acid. Keywords: Effervescent granules, citric acid, tartaric acid, sodium bicarbonate
Minimalisasi Biaya Obat Antihipertensi Lisinopril Atau Candesartan Pada Pasien Hipertensi Disertai Gagal Ginjal Kronik Di Instalasi Rawat Inap RSUD Dr. H. Abdul Moeloek Septiani, Anastya Devi; Rooswita, Putri Amelia; Handayani, Kiki Yuli
PharmaCine : Journal of Pharmacy, Medical and Health Science Vol 5 No 1 (2024): PharmaCine: Journal of Pharmacy, Medical and Health Science
Publisher : Bachelor of Pharmacy Study Program, Faculty of Health Sciences, Universitas Singaperbangsa Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35706/pc.v5i1.11239

Abstract

Hypertension can damage blood vessels, which if not handled properly can cause kidney damage. Chronic Kidney Disease (CKD) is the most common comorbid in hypertensive patients in Indonesia with a percentage of 51%. The successful treatment of hypertension accompanied by CKD can be supported by administration of antihypertensives. The variety of antihypertensive therapy alternatives makes pharmacoeconomic studies necessary in order to obtain cost-effective therapy. The purpose of this study was to find out which antihypertensive drug is the most cost-minimizing between lisinopril and candesartan used in the treatment of hypertension accompanied by CKD (ICD-10 I12.0) in the Inpatient Installation based on the perspective of RSUD Dr. H. Abdul Moeloek in 2022. This research is a non-experimental observational with a purposive sampling technique. Data collection was carried out retrospectively from tracking secondary data originating from medical records, drug details in the Hospital Information System (SIRS), and details of direct medical costs in the Hospital Finance Department. Costs collected are in the form of direct medical costs which include antihypertensive drug costs, supporting drug costs, accompanying drug costs, laboratory costs, ICU, emergency room, hemodialysis, and hospitalization. The study showed that the average total cost of treating antihypertensive therapy for lisinopril was higher than candes artan, with lisinopril amounting to Rp 3.778.163 while candesartan was Rp 3.307.740. These results indicate that use of the antihypertensive candesartan is more cost-minimizing compared to lisinopril with a saving value of IDR Rp 470.423. Keywords: Pharmacoeconomics; CMA; hypertension with CKD; lisinopril; candesartan
Uji Kandungan Formalin pada Sampel Ikan Asin dan Ikan Segar yang Dijual di Pasar Tradisional Haetami, Kiki; Karlina, Lina; Junianto, Junianto
PharmaCine : Journal of Pharmacy, Medical and Health Science Vol 5 No 1 (2024): PharmaCine: Journal of Pharmacy, Medical and Health Science
Publisher : Bachelor of Pharmacy Study Program, Faculty of Health Sciences, Universitas Singaperbangsa Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35706/pc.v5i1.11339

Abstract

Background: Fish is a commodity that quickly deteriorates and spoils. One method commonly used to extend the shelf life of fish is by storing at low temperatures and salting. However, both methods are relatively expensive, so many sellers prefer to use formalin as a preservative for food products. Aim: This study aims to determine the use of formalin in salted fish and fresh fish in traditional markets. Methode: Testing was carried out qualitatively and quantitatively using the MERCK formalin test kit. Results: Test results on the formalin content of wais salted fish, skinned shark salted fish and salmon from the upper market of Cimahi obtained positive results in all three samples. Each formalin level is 0.10 mg/l; 0.80 mg/l; and 0.25 mg/l. Conclusion: The use of formalin in food products in traditional markets is still carried out by fish sellers. Keywords:  Formalin, Salted Fish, Fresh Fish, Traditional Market
Identifikasi Kandungan Bakteri Vibrio cholerae pada Produk Olahan Pepes Ikan Tuna (Thunnus sp.): Identification of the Bacterial Content of Vibrio cholerae On Tuna Fish Pepes (Thunnus sp.) Haetami, Kiki; Hanun, Inas Maya Tamimah
PharmaCine : Journal of Pharmacy, Medical and Health Science Vol 5 No 2 (2024): PharmaCine: Journal of Pharmacy, Medical and Health Science
Publisher : Bachelor of Pharmacy Study Program, Faculty of Health Sciences, Universitas Singaperbangsa Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35706/pc.v5i2.12009

Abstract

Tuna (Thunnus sp.) is one of the potential fishery products because it has a high protein content. Tuna fish can be processed into various kinds of processing, one of which is pepes ikan which is a traditional Indonesia dish. Processed fishery products such as pepes can also experience a decrease in quality, one of which can be caused by the presence of bacteria, such as Vibrio cholerae bacteria. Vibrio cholerae is an opportunistic pathogen in estuarine and marine environments. These bacteria can be transferred into the food matrix causing illness if consumed by humans. The purpose of this study is to identify the content of Vibrio cholerae bacteria in tuna fish pepes processed products. The results of biochemical tests based on SNI 01-2332.4-2006 show that tuna fish pepes originating from one MSME in the Special Region of Yogyakarta does not contain or are negative for Vibrio cholerae so that it is suitable for marketing and human consumption. Keywords: Microbiology, Fishery Products, Processed Products, Tuna Fish, Vibrio cholerae.
Faktor Perilaku Yang Berhubungan dengan Kejadian Hipertensi di Puskesmas Serpong I, Kota Tangerang Selatan: Behavioral Factors Associated with the Incidence of Hypertension at Serpong I Primary Health Care, South Tangerang City Raditya, Muhammad Nurul; Alnur, Rony Darmawansyah
PharmaCine : Journal of Pharmacy, Medical and Health Science Vol 5 No 2 (2024): PharmaCine: Journal of Pharmacy, Medical and Health Science
Publisher : Bachelor of Pharmacy Study Program, Faculty of Health Sciences, Universitas Singaperbangsa Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35706/pc.v5i2.12081

Abstract

Background: Hypertension is frequently regarded as a significant health concern. This is corroborated by the annual increase in hypertension cases. Behavioral factors, including smoking, physical activity, consumption of salty foods, and consumption of fatty foods, have been identified as risk factors for hypertension. Objective: The objective of this study is to examine the behavioral factors associated with the incidence of hypertension at the Serpong I Primary Health Care in South Tangerang City in 2024. Methods: The study employed a quantitative research design with a cross-sectional study structure and an analytic approach, utilizing the Chi-square test was conducted to examine the relationship between the independent variables and the incidence of hypertension. The study was conducted over a period of six months, from February to August 2024. The population under investigation in this study consisted of all individuals who visited the Serpong I Primary Health Care in South Tangerang City. The sample size for this study was 101 individuals, selected using the purposive sampling technique. The data were subjected to univariate and bivariate analyses. Results: The frequency distribution demonstrated that a greater proportion of respondents did not smoke (74, 73.3%), engaged in sufficient physical activity (72, 71.3%), consumed excessive amounts of salty foods (53, 52.5%), and consumed fatty foods (53, 52.5%). The results of the Chi-square test indicate that the variable most strongly associated with the incidence of hypertension (Pvalue <0.05) is the consumption of salty foods (P-value <0.001). While variables that are not associated (Pvalue > 0.05) include smoking (Pvalue = 0.661), physical activity (Pvalue = 0.173), and consumption of fatty foods (Pvalue = 0.079). Conclusion: The findings indicate a correlation between excessive sodium consumption and the prevalence of hypertension at the Serpong I Primary Health Care in South Tangerang in 2024. It is recommended that respondents to reduce the consumption of foods with high sodium content. Keywords: Hypertension; Risk Factors; Behavior;Primary Health Care.

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