cover
Contact Name
Amin Harahap
Contact Email
adminijhet@afdifaljournal.com
Phone
+6285257133690
Journal Mail Official
adminijhet@afdifaljournal.com
Editorial Address
Jl. Sempurna Perum. AA Residence Blok B. No. 8 Aek Tapa.
Location
Unknown,
Unknown
INDONESIA
International Journal of Health, Engineering and Technology
ISSN : -     EISSN : 28298683     DOI : https://doi.org/10.55227/ijhet.v1i1
International Journal of Health, Engineering and Technology (IJHET) is to provide research media and an important reference for the progress and dissemination of research results that support high-level research in the field of Health, Engineering and technology. Original theoretical work and application-based studies, which contribute to a better understanding of all areas of Health, Engineering and Technology , the journal publishes articles six times a year in May, July, September, November, January and March. Scope: International Journal of Health, Engineering and Technology (IJHET) is to provide a research medium and an important reference for the advancement and dissemination of research results that support high-level research in the fields of Health, Engineering and Technology Research. Original theoretical work and application-based studies, which contributes to a better understanding all fields of Health, Engineering and Technology Research. Healt : Clinical Nutrition, Community Nutrition, Institutional Nutrition, Food Technology, Food Security, Pediatric Physiotherapy, Geriatric Physiotherapy, Cardiovascular and Pulmonary Physiotherapy, Musculoskeletal Physiotherapy, Sports Physiotherapy, Public Health, Community Sanitation, Environmental Health, Nursing, Biology, Medicine, Pharmacy. Engineering : The field of mechanical Engineering include expertise in energy conversion, construction machinery, manufacturing and materials. The field of Electrical Engineering which includes skills power engineering, telecommunications engineering and information, as well as control and instrumentation. The field of Chemical Engineering which includes expertise in the field of new and renewable energy, the environment field. The field of Civil Engineering which includes expertise in the fields of structural, geotechnical, transportation and water. The field of Metallurgical Engineering which includes expertise in extraction, manufacturing and characterization of materials. The field of Industrial Engineering which includes enterprise management system, working system and the ergonomics and manufacturing systems. Technology: Open Source Application, Information Management, Information System, IT & Social Impact, Geographical Information System, Web Engineering, Database Design & Technology, Data Warehouse, Network Security, Data Mining, Computer Architecture Design, Mobile Programming.
Articles 417 Documents
Analysis Of The Relationship Between Pharmacists' Knowledge, Attitude, And Perception Levels Towards Telepharmy Implementation In Sukoharjo Regency Fiska Febriani Fikri; Kharisma Jayak Pratama; Hidayah Apriliawan
International Journal of Health Engineering and Technology Vol. 4 No. 6 (2026): IJHET MARCH 2026
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55227/ijhet.v4i6.660

Abstract

The Covid-19 pandemic has accelerated the adoption of technology in healthcare services, including the implementation of telepharmacy. The success of telepharmacy implementation depends on the readiness of pharmacists in terms of their knowledge, attitudes, and perceptions. This study aims to analyze the relationship between the level of knowledge, attitudes, and perceptions of pharmacists towards the implementation of telepharmacy in the Sukoharjo Regency. This study is a qualitative descriptive study with a cross-sectional approach. The study sample consisted of 30 pharmacists working in pharmacies and community health centers in Sukoharjo Regency, selected using purposive sampling. Data were collected using a questionnaire that had been tested for validity and reliability, as well as in-depth interviews. Data analysis included univariate and bivariate analysis with chi-square. The results showed that the majority of pharmacists had a good level of knowledge (mean 76.7%), indicating that pharmacists had a good understanding. Pharmacists' attitudes were in the adequate category (mean 60%), and pharmacists' perceptions were in the adequate category (mean 70%). Statistical analysis using chi-square indicated that there was a significant relationship between pharmacists' knowledge and perceptions, with a p-value of 0.014 (p <0.05). There was a significant relationship between the variables of attitude and perception, as indicated by a p-value of 0.001 (p <0.05). The conclusion of the implementation of tele-pharmacy is not only in terms of knowledge, but also in strengthening positive attitudes through supportive infrastructure, technical training, and clear regulations.
Evaluation Of Sun Protection Factor Value Of Water, Ethyl Acetate, And N-Hexane Fractions Of Ethanolic Extract Of Crystal Guava Fruit (Psidium Guajava. L.) By UV-VIS Spectrophotometry Farida Kumalasari; Rahmat Hidayat; Tiara Ajeng Listiyani
International Journal of Health Engineering and Technology Vol. 4 No. 6 (2026): IJHET MARCH 2026
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55227/ijhet.v4i6.661

Abstract

Excessive exposure to ultraviolet (UV) rays can cause various skin damage, so an effective and safe sunscreen preparation is needed. Natural ingredients, especially crystal guava fruit (Psidium guajava L.), are known to contain secondary metabolite compounds such as flavonoids that have the potential as natural photoprotective agents. Crystal Guava Fruit (Psidium guajava L.) contains several secondary metabolite compounds, namely flavonoids, saponins, and terpenoids. The content of secondary metabolites plays a role as a Sun Protection Factor, because these compounds are able to absorb UV A and UV B rays well. This study aims to determine the Sun Protection Factor (SPF) value of ethyl acetate, n-Hexane, and water fractions from crystal guava fruit (Psidium guajava L.) in vitro using the UV-Vis spectrophotometry method and to determine the fraction with the best sunscreen activity. The extract was prepared by maceration using 96% ethanol solvent, then the extract was fractionated in stages using n-Hexane, ethyl acetate, and water. SPF values ​​were determined in vitro using UV-Vis spectrophotometry at a wavelength of 290-320 nm. Each fraction was prepared in several concentrations: 200, 400, 600, 800, and 1000 ppm. The study showed that all fractions had sunscreen activity with SPF values ​​that increased with increasing concentration. The ethyl acetate fraction showed the highest activity with an SPF value of 24.249 at a concentration of 1000 ppm which is included in the ultra protection category. This study shows that the water, ethyl acetate, and n-Hexane fraction of crystal guava fruit (Psidium guajava L.) have the potential as SPF because they are in the range 2-4 (minimum category).
Antibacterial Activity Test Of Ethanol Extract And N-Hexane Fraction, Ethyl Acetate, Moringa Leaf Water (Moringa Oleifera L) Against Streptococcus Mutans ATCC 25175 Bacteria Wahdah Sri Rahayu; Tatiana Siska Wardani; Tiara Ajeng Listyani
International Journal of Health Engineering and Technology Vol. 4 No. 6 (2026): IJHET MARCH 2026
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55227/ijhet.v4i6.662

Abstract

Dental caries remains a major oral health problem globally and in Indonesia, triggered by Streptococcus mutans biofilm. Chemical agents such as chlorhexidine have side effects, encouraging the use of natural alternatives from Moringa oleifera L. leaves. This study aims to evaluate the antibacterial activity of ethanol extracts and n-hexane, ethyl acetate, and water fractions against Streptococcus mutans ATCC 25175, identify the most active fraction, and determine the MIC and MBC. This quantitative study used diffusion and dilution methods. Bacteria: Streptococcus mutans ATCC 25175; samples: ethanol extract of Moringa oleifera L. leaves and n-Hexane, ethyl acetate, and water fractions. Data analysis used SPSS 25 One-Way ANOVA, Tukey (p<0.05). Results showed that the ethyl acetate fraction was the most active with 12.36 mm inhibition at 45%; MIC and MBC were 30% ANOVA significant (p=0.000). The ethyl acetate fraction has strong caries prevention potential, supporting herbal development.
Antibacterial Activity Test Of Extract, N-Hexane Fraction, Ethyl Acetate And Water Of Kesum Leaves (Polygonum Minus H) Against Escherichia Coli ATCC 25922 Bacteria Wahana Ayu Saputri; Tatiana Siska Wardani; Anna Fitriawati
International Journal of Health Engineering and Technology Vol. 4 No. 6 (2026): IJHET MARCH 2026
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55227/ijhet.v4i6.663

Abstract

Diarrheal disease caused by Escherichia coli is a serious health problem in Indonesia, especially in toddlers, with increasing antibiotic resistance. Kesum leaves (Polygonum minus H.) have antibacterial potential because they contain flavonoids, phenols, alkaloids, and saponins. To evaluate the antibacterial activity of 70% ethanol extract and fractions of n-hexane, ethyl acetate, and kesum leaf water against E. coli ATCC 25922, to identify effective concentrations, and to determine the MIC and MBC of the most active fraction. Laboratory experimental study with 70% ethanol maceration extraction and liquid-liquid fractionation. E. coli ATCC 25922 population, 7 kg of simplex samples from Sambas, West Kalimantan. Instruments include an incubator, SPSS 25. Analysis techniques: disc diffusion, liquid/solid dilution, ANOVA.  The ethyl acetate fraction was the most effective (inhibition zone 12.36 mm, at a concentration of 40%, strong category), followed by the extract (inhibition zone 11.31 mm, at a concentration of 30%, medium category), n-hexane (10.46 mm), water (8.86 mm). MIC and MBC of the ethyl acetate fraction were 30%. The extract and fraction of kesum leaves have moderate to strong antibacterial activity against E. coli ATCC 25922, supporting the development of anti-diarrhea herbal medicine.
Troponin Profile Of Clopidogrel And Ticagrelor With Old Generation PPIs In Myocardial Infarction Patients Erlisa Ika Yuni Pramesti; Kharisma Jayak Pratama; Hidayah Apriliawan
International Journal of Health Engineering and Technology Vol. 4 No. 6 (2026): IJHET MARCH 2026
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55227/ijhet.v4i6.664

Abstract

Myocardial infarction is a leading cause of cardiovascular death in Indonesia with an increasing prevalence. The interaction of clopidogrel-ticagrelor with older-generation PPIs can affect antiplatelet efficacy and troponin levels. This study aims to describe troponin levels in the use of clopidogrel and ticagrelor with older-generation PPIs and their relationship to patient characteristics and lipid profiles. A retrospective descriptive observational method was conducted on 76 myocardial infarction patients at March eleventh University Hospital (November 2024-November 2025) using medical record data. Univariate (frequency, mean) and bivariate (Chi-Square, p<0.05) analyses were processed using SPSS. The results showed that the majority of patients were male (66%), aged 46-65 years (64%). There was no significant association between gender (p=0.542), age (p=0.415), clopidogrel-PPI (p=0.346), ticagrelor-PPI (p=0.368), and LDL (p=0.100) with troponin, but triglycerides were significantly associated (p=0.040). The average troponin of clopidogrel was 9.465 ng/L, higher than that of ticagrelor (3.879 ng/L). It was concluded that triglycerides significantly influenced troponin, while patient characteristics and the combination of antiplatelet-PPI did not.
Verification Of the Analysis Method For Determining Cetirizine HCl Levels in Cetirizine Syrup Preparations By High-Performance Liquid Chromatography According To The Compendial Method Of The Indonesian Pharmacopoeia, VIth Edition, 2020 Nanda Putri Kamilah; Hasriyani Hasriyani; M. Khudzaifi
International Journal of Health Engineering and Technology Vol. 4 No. 6 (2026): IJHET MARCH 2026
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55227/ijhet.v4i6.666

Abstract

Cetirizine Hydrochloride is a second-generation antihistamine that is effective for allergy therapy and is widely used in syrup dosage forms. The quality of drug preparations requires a valid assay analysis method to ensure the active substance content meets the requirements. This study aims to verify the analysis method for determining the content of Cetirizine Hydrochloride in syrup preparations using High Performance Liquid Chromatography (HPLC) in accordance with the Indonesian Pharmacopoeia Edition VI 2020 standards. The study was conducted at the Quality Control Laboratory of PT. X using an HPLC system equipped with an L10 column and UV detector set at 233 nm. Method verification parameters include system suitability testing, specificity, accuracy, precision, as well as linearity and range in determining the content of Cetirizine Hydrochloride. The results demonstrated that all verification parameters met the acceptance criteria. The system suitability test gave good results with an area RSD value of 0.232% and a tailing factor of 1.389. The method was proven to be specific with a retention time of 24.842 minutes without interference from the matrix. The accuracy of the assay method was confirmed with an average recovery value of 101.06% in the concentration range of 80–120% of the nominal concentration, and excellent precision with an RSD value of 0.31%. Linearity and range tests showed an excellent linear relationship in the concentration range of 80–120% with a correlation coefficient (r) of 0.9996. Based on these results, the analysis method for determining the content of Cetirizine Hydrochloride in syrup preparations was declared valid and suitable for use in routine quality control analysis.
Formulation Of Antifungal Solid Soap From 96% Ethanol Extract Of Neem Leaves (Azadirachta Indica A.Juss) Against Malassezia Furfur ATCC 14251 Diyah Nurayuni; Anna Fitriawati; Annie Rahmatillah
International Journal of Health Engineering and Technology Vol. 4 No. 6 (2026): IJHET MARCH 2026
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55227/ijhet.v4i6.667

Abstract

Fungal skin infections are still a health problem in tropical regions, especially those caused by Malassezia furfur, so alternative natural skin cleansing preparations are needed that are safe and effective. Neem leaves (Azadirachta indica A. Juss) are known to have antifungal activity and have the potential to be developed into solid soap preparations. This study aims to formulate an antifungal solid soap made from 96 percent ethanol extract of neem leaves, evaluate the physical quality of the preparation, and test its antifungal activity against Malassezia furfur. This study is a laboratory experimental study with a pretest-posttest only control group design. The study population was neem leaves obtained from Mount Pati District, Semarang, with simplicia samples selected using a purposive sampling technique. The research instruments included formulation equipment, physical quality tests based on SNI 3532:2016, and antifungal activity tests using the well diffusion method, while data analysis was carried out using nonparametric statistical tests. The results showed that all soap formulas met the physical quality requirements, and the formulation with a 10 percent extract concentration produced the largest inhibition zone diameter against Malassezia furfur, although it was still relatively weak. The conclusion of this study is that neem leaf extract solid soap has potential as a natural skin cleanser with antifungal activity, but further development and optimization of the formulation are needed to increase its effectiveness.
The Relationship Of Antibiotic Rationality To Clinical Outcomes In Adult UTI Patients Using The Gyssens Method At The Inpatient Unit Of PKU Muhammadiyah Hospital, Surakarta Nabilla Aulia Khorifatunnisa; Aprilia Puteri Santika; Annie Rahmatillah
International Journal of Health Engineering and Technology Vol. 4 No. 6 (2026): IJHET MARCH 2026
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55227/ijhet.v4i6.668

Abstract

Urinary Tract Infection (UTI) is a common infection with a high risk of antibiotic resistance due to irrational use. This study evaluated the rationality of antibiotics on the clinical outcomes of adult UTI patients using the Gyssens method at PKU Muhammadiyah Surakarta Hospital. To analyze the profile, rationality of antibiotics, and their relationship with clinical improvement. Retrospective descriptive study on 77 adult UTI inpatients from January to December 2024, purposive sampling, medical record instruments, Gyssens and Chi-Square analysis (SPSS 25). Rationality 53.25% (category 0), Cefuroxime most (38.96%), normal leukocytes 92.2%, p = 0.006 indicating a significant relationship between rationality and clinical improvement. Rational use of antibiotics significantly improves the clinical outcomes of UTI, supporting antimicrobial stewardship.
Antibacterial Activity Test Of Extract And Fraction Of N-Hexane, Ethyl Acetate And Water Of Pineapple Peel (Ananas Comosus (L.) Merr.) Against Staphylococcus Epidermidis ATCC 12228 Bacteria Nadia Nurul Wachida; Tatiana Siska Wardani; Rahmat Hidayat
International Journal of Health Engineering and Technology Vol. 4 No. 6 (2026): IJHET MARCH 2026
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55227/ijhet.v4i6.670

Abstract

Staphylococcus epidermidis is a bacteria that causes mild skin infections accompanied by abscesses, with a high  prevalence in Indonesia, requiring natural alternatives due to antibiotic resistance. This study aimed to evaluated antibacterial activity of 96% ethanol extract and n-hexane, ethyl acetate, water fractions of pineapple peel (Ananas comosus L. Merr.) against S. epidermidis ATCC 12228 and to determined MIC/MBC of the most active fraction. This quantitative and experimental study used the disk diffusion and liquid/solid dilution. methods. Population: pineapple peels from Blitar, East Java; sample: 700 g Simplicia powder. The nstruments included rotary evaporator, incubator, autoklaf, laminar air flow; data were analyzed using the Kruskal-Wallis (SPSS 25). Results showed that extract produced inhibition zones ranging from 5.63–11.43 mm, ethyl acetate fraction 3.80–7.55 mm, water 2.35–6.88 mm, n-hexane was inactive. The MIC and MBC values of the extract were 25%; ethyl acetate fraction MIC and MBC were 50%. Extract, ethyl acetate, and water fractions exhibited antibacterial activity aginst S. epidermidis, with extract being the most effective.
The Relationship Between Severity Level And Quality Of Worship Among Muslim Patients Undergoing Hemodialysis At PKU Muhammadiyah Hospital, Gamping Siti Nurhaliza; Ruhyana Ruhyana; Aini Inayati
International Journal of Health Engineering and Technology Vol. 4 No. 6 (2026): IJHET MARCH 2026
Publisher : CV. AFDIFAL MAJU BERKAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55227/ijhet.v4i6.671

Abstract

The quality of worship is related to the level of devotion and spiritual appreciation in daily life. Chronic kidney failure is a condition that progressively affects kidney function and requires hemodialysis as replacement therapy. This condition can affect the ability of Muslim patients to perform their daily worship. Although spiritual aspects are important in health care, research on the relationship between disease severity and quality of worship in hemodialysis patients is still limited, especially in Indonesia. This study aims to analyze the relationship between disease severity and the quality of worship among Muslim patients undergoing hemodialysis at PKU Muhammadiyah Gamping General Hospital. This study used a descriptive correlational method with a cross-sectional approach. A total of 62 respondents were selected using random sampling. Data were collected using a research instrument that had been tested by three experts. Data analysis was performed using Spearman's rank correlation. The results showed that there was no significant relationship between disease severity and the quality of worship among Muslim patients undergoing hemodialysis (r = 0.174; p = 0.175). This study indicates that disease severity does not affect the quality of worship among hemodialysis patients, meaning that patients can maintain their worship practices despite experiencing severe illness.