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INDONESIA
Jurnal Farmasi Indonesia
Published by Ikatan Apoteker Indonesia
ISSN : 14121107     EISSN : 2355696X     DOI : https://doi.org/10.35617/jfionline
Core Subject : Health,
Medicine & Pharmacology
Jurnal Farmasi Indonesia adalah jurnal nasional (peer-reviewed) yang diterbitkan oleh Ikatan Apoteker Indonesia dua kali dalam setahun sebagai sarana diseminasi ilmu pengetahuan di bidang farmasi, yaitu: farmasi klinis, farmasi masyarakat/komunitas, kimia farmasi, biologi farmasi/famakognosi, farmakologi, pengembangan obat/kimia medisinal, formulasi dan bidang terkait. Artikel yang dipublikasi berupa hasil penelitian dan mini-review. JFIOnline telah mulai diterbitkan sejak tahun 2009 dalam edisi cetak. Pada tahun 2014 mulai dibuat edisi online. Akses artikel pada jurnal tidak berbayar, tetapi dikenakan biaya proses publikasi untuk penulis (open access journal). Mulai bulan Juli 2019 jurnal ini dapat diakses di alamat yang baru yaitu www.jfi-online.org dari alamat sebelumnya www.jfionline.org.
Arjuna Subject : Profesi Kesehatan - Farmasi
Articles 149 Documents
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PERBEDAAN EFEKTIVITAS EDUKASI BEYOND USE DATE MELALUI BUKU SAKU DAN VIDEO TERHADAP TINGKAT PENGETAHUAN Veronica, Elsa Ignatia; Arrang, Sherly Tandi; Notario, Dion
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 13 No. 2 (2021): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (334.339 KB) | DOI: 10.35617/jfionline.v13i2.14

Abstract

The stability of drug preparations is very important to maintain because it can affect the quality, effectiveness, and safety of these drug preparations. If the product's primary packaging is opened, the stability of the preparation is changed. The product's stability duration is correlated with the expiration date. The expiration date of the product after opened from its original packaging or mixed with other preparations is known as the beyond-use date (BUD). Research on the level of public knowledge about BUD still needs to be improved, and the results of several studies show that the community needs to learn and understand BUD. Therefore, a study was conducted to assess differences in the effectiveness of educational media (pocketbook and video) on knowledge related to BUD. Quasi-experimental research design with the type of pre-test & post-test two groups. The number of respondents in this research was 70, divided into two: pocketbooks (35 respondents) and videos (35 respondents). Based on the analysis results, it was found that there was a change in the respondents' knowledge after being given education. As many as 60% of respondents in the pocketbook group had insufficient knowledge before being given education, and after being given education, 74% of respondents had good knowledge (p=0.01). In the video group, there was an increase in the good knowledge respondent group; namely, before being given education, the number was 37%, increasing to 43% after being given education (p=0.01). The regression analysis showed that educational media significantly influenced respondents' knowledge related to BUD (p=0.04). The ducation with a pocketbook and video increases knowledge about BUD, but videos provide a better increase in knowledge.
LAPORAN KASUS-METRONIDAZOLE TABLET MENYEBABKAN PERUBAHAN WARNA URINE Sherly Tandi Arrang
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 12 No. 2 (2020): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (686.979 KB) | DOI: 10.35617/jfionline.v12i2.15

Abstract

Seorang pasien wanita usia 38 tahun mengalami keputihan dan diberikan terapi metronidazole. Pasien mengalami efek samping obat berupa warna urin menjadi gelap kemudian merah beberapa jam setelah penggunaan metronidazole oral 500 mg tablet. Hubungan antara tablet metronidazole dan perubahan warna urin dinilai menggunakan Skala Naranjo. Berdasarkan dari penilaian efek samping obat menggunakan instrumen Naranjo Scale, dari 10 pertanyaan didapatkan total skor tujuh (7), yang artinya metronidazole kemungkinan penyebab warna urin menjadi lebih gelap/merah. Perubahan warna urin menjadi gelap atau kemerahan disebabkan oleh pigmentasi dari metabolit metronidazole. Metronidazole dikaitkan dengan warna urin menjadi gelap/kemerahan, dan warna urin kembali normal setelah obat dihentikan.
Assesment of Health-Related Quality of Life with Patient Chronic Kidney Disease Fajriansyah Fajriansyah; Mujriah; Zulfahmidah
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 12 No. 2 (2020): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (320.157 KB) | DOI: 10.35617/jfionline.v12i2.16

Abstract

Measuring the quality of life can be used as a reference for the success of an action or therapy as well as initial data in formulating the right action for the patient. This study aims to provide an overview of the quality of life of patients with chronic renal failure who seek treatment at the Hasanuddin University hospital. The research design used was an observational cross-sectional design with data collection carried out by filling out a questionnaire prospectively. The subjects of the study were chronic renal failure patients undergoing hemodialysis who met the inclusion criteria and were selected using a non-random sampling technique by means of total sampling. The patient's quality of life was measured using the Kidney Disease Quality of Life Short Form (KDQOL-SF™) Indonesian version 1.3 questionnaire. A total of 30 patients were willing to participate in this study. The results of the study on 30 patients with chronic renal failure, there were 7 out of 19 scale/item having a not good, namely burden of kidney disease, work status, sleep, physical functioning, role-physical, pain, and general health. The average value of 19 scale/item shows an average score of> 59.37, which is 63.86 which belongs to the good quality of life category.
Pengaruh Asuhan Kefarmasian Terhadap Outcome Klinis Dan Kualitas Hidup Pada Pasien Diabetes Melitus Tipe 2 Khairunnisa; Rawitri, Kiki; Wiryanto; Wahyuni, Sri
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 13 No. 2 (2021): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (418.72 KB) | DOI: 10.35617/jfionline.v13i2.18

Abstract

The role of pharmacists in pharmaceutical care has been shown to improve therapeutic outcomes in patients with diabetes mellitus (DM) in various countries. This study aims to implementation of pharmaceutical care and determine its impact on clinical outcomes and quality of life of type 2 DM patients at the community pharmacies. This study used a comparative experimental method with a prospective cohort study design before and after intervention on 38 types 2 DM patients who met the inclusion criteria at one of the community pharmacies in Medan city in August-December 2020. Clinical outcome data included random blood glucose (RBG) levels and HbA1c values ​​were obtained from direct examination of the patient, and quality of life data was obtained using the EQ-5D-3L questionnaire. The data were analyzed using the Wilcoxon Signed-Rank test and the Friedman test in the SPSS V22.0. program The results showed that the mean RBG value before the intervention was 278.58 ± 75.278 mg/dl and after the intervention, there was a decrease of 179.68 ± 14.008 mg/dl (α<0.05), the HbA1c value was 9.021 ± 1.029% to 8.368 ± 1.049% (α<0.05). There was a significant increase in the average quality of life index before the intervention from 0.849 ± 0.1266 and after the intervention to 0.967 ± 0.0657 (α <0.05). Based on the results of the study, it was concluded that the implementation of pharmaceutical care had an impact on improving clinical outcomes and quality of life in type 2 DM patients at community pharmacy
Faktor Yang Mempengaruhi Kejadian Diare Pada Balita Di Wilayah Kerja Puskesmas Panambungan Makassar Fattah, Nurfachanti; Zulfahmidah, Zulfahmidah; Darma, Sidrah; Syahruddin, Febie Irsandy; Bakri, Sri Intan Akmal
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 14 No. 1 (2022): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (419.844 KB) | DOI: 10.35617/jfionline.v14i1.19

Abstract

Diarrhea is a bowel disorder characterized by defecation more than 3 times a day with the consistency of liquid stools may be accompanied by blood. The World Health Organization (WHO) in 2017 stated that diarrheal disease is the main cause of child mortality and morbidity in the world. The purpose of this study was to analyze the factors related to the incidence of diarrhea in children under five in the work area of ​​the Panambungan Health Center Makassar City in 2021. Method in this type of research was an analytical observational study with a cross sectional type of research, with a sample size of 91 mothers under five with purposive sampling technique. The results of chi-square analysis were that there was a relationship between the incidence of diarrhea under five and mother's knowledge (p = 0.000), hand washing behavior (p = 0.000) and there was no relationship between the incidence of diarrhea under five and nutritional status (p = 0.174) and water sources net (p=0.269). In conclusion, there is a relationship between the level of mother's knowledge and handwashing behavior with the incidence of diarrhea in toddlers in the working area of ​​the Panambungan Makassar Health Center in 2021.
The THE PARE FRUIT ACTIVITY (Momordica charantia L.) AS HERBAL ANTI-HYPERGLYCEMIC FOR DIABETES MELLITUS CONDITIONS: LITERATURE REVIEW: AKTIVITAS BUAH PARE (Momordica charantia L.) SEBAGAI HERBAL ANTI HIPERGLIKEMIA PADA KONDISI DIABETES MELITUS: LITERATURE REVIEW Ikhwan Yuda Kusuma; Yuli Yuli Maesaroh
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 12 No. 2 (2020): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (309.876 KB) | DOI: 10.35617/jfionline.v12i2.20

Abstract

Diabetes mellitus (DM) is a metabolic disorder characterized by high blood glucose (hyperglycemia) and impaired carbohydrate, fat, and protein metabolism due to effects on insulin secretion and insulin sensitivity. Oral antidiabetic is one of the therapeutic options to control blood glucose although its use has the potential for side effects and is very detrimental, especially in long-term use. Complementary therapies made from herbs such as bitter melon (Momordica charantia L.) are potential aspects to be alternative therapies because of the potential for lower side effects and affordable costs. This study describes the activity of bitter melon (Momordica charantia L.) as an antihyperglycemic agent. This type of research is a literature review which is described descriptively. The literature search method uses international and national journals conducted by online and identified using electronic databases from PubMed, Science Direct and Google Scholar. The data collection process uses the PICO (Population, Intervention, Compare, Outcome) approach. The results of this study showed that bitter melon (Momordica charantia L.) contains antidiabetic compounds including charantin and polypeptide-p. Bitter gourd, both in extract and non-extract form and in single or in combination, has been shown to reduce blood glucose levels, increase insulin sensitivity and levels, normalize HbA1c levels, improve lipid profiles and reduce oxidative stress. The conclusion of this study is that bitter melon has the potential as an antihyperglycemic herb in diabetic conditions.
Potensi POTENSI DAUN KELOR (Moringa oleifera) SEBAGAI AGEN ANTI-HIPERGIKEMIA : STUDI LITERATUR REVIEW: POTENTIAL OF MORINGA LEAF (Moringa oleifera) AS ANTI-HYPERGLICEMIC AGENT: A LITERATUR REVIEW Ikhwan Yuda Kusuma; Yuyun Pujiarti; Galih Samodra
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 12 No. 1 (2020): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (343.846 KB) | DOI: 10.35617/jfionline.v12i1.21

Abstract

Diabetes Melitus (DM) dikenal sebagai gangguan metabolisme karbohidrat yang ditandai dengan tingginya kadar gula dalam darah (hiperglikemia). Menurut data International Diabetes Federation (IDF) 2017, jumlah diabetisi mencapai 415 juta jiwa dan diperkirakan akan terus meningkat pada tahun 2040 sekitar 642 juta jiwa (55%). Salah satu alternatif pengobatan untuk menanggulangi penyakit diabetes yaitu tanaman herbal diantaranya daun kelor (Moringa oleifera) yang kaya akan nutrisi, seperti phytochemical, karoten, senyawa flavonoid, senyawa phenoid, kalsium, besi, protein, vitamin serta memiliki kandungan antioksidan yang dapat menstabilkan radikal bebas sehingga dapat dijadikan proteksi terhadap diabetes melitus. Tujuan Penelitian ini yaitu untuk mengetahui potensi daun kelor (Moringa oleifera) dalam menurunkan kadar gula darah berdasarkan data ilmiah yang dikumpulkan. Metode penelitian ini menggunakan metode literatur Review dengan pencarian jurnal ilmiah secara online pada database Science Direct dan Google Scholar terbitan tahun 2010-2020 dengan teknik pengumpulan data menggunakan pendekatan PICO (Population, Intervention, Comparasion, Outcome). Hasil tinjauan literatur beberpaa jurnal, daun kelor (Moringa oleifera) berpotensi sebagai penurun kadar glukosa darah yang sangat efektif, selain itu daun kelor (moringa oleifera) menunjukkan pengaruh yang signifikan terhadap profil lipid, resistensi insulin, penurunan glukosa darah, dan penurunan berat badan secara signifikan. Hal ini menunjukkan bahwa daun Moringa oleifera terbukti memiliki efek dapat menurunkan kadar gukosa dalam darah.
Aktivitas AKTIVITAS ANTIKOLESTEROL KOMBINASI EKSTRAK EKSOKARP BUAH SEMANGKA (Citrullus Lanatus (Thunb.)) DAN EKSTRAK DAUN SALAM (Syzygium polyanthum) PADA MENCIT JANTAN GALUR balb/c: ANTICHOLESTEROL ACTIVITY OF WATERMELON EXOCARP EXTRACT (Citrullus Lanatus (Thunb.)) AND BAY LEAF EXTRACT (Syzygium Polyanthum) IN MALE MICE OF balb/c STRAIN Ikhwan Yuda Kusuma; Noryana; Peppy Octaviani
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 12 No. 1 (2020): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (365.887 KB) | DOI: 10.35617/jfionline.v12i1.22

Abstract

Penelitian ini bertujuan untuk mengetahui perbandingan efek ekstrak eksokarp buah semangka (citrullus lanatus (thunb.)) dengan ekstrak daun salam (syzygium polyanthum) serta kombinasi keduanya dalam menurunkan kadar kolesterol. Induksi hiperkolesterolemia dilakukan dengan pemberian suspensi propiltiourasil (PTU). Metode penelitian ini dilakukan secara eksperimental dengan rancangan Pre-test dan Post-test with control group. Mencit dibagi menjadi 6 kelompok yaitu kelompok perlakuan (1, 2, dan 3) dan kontrol negatif (K-), kontrol positif (K+), dan kontrol normal. Dosis yang digunakan yaitu K1 ekstrak eksokarp buah semangka 500 mg/kgBB, K2 ekstrak daun salam 400 mg/kgBB, dan K3 kombinasi ekstrak eksokarp buah semangka dan ekstrak daun salam 500;400 mg/kgBB. Sedangkan kelompok K- diberikan Na-CMC 1%, K+ diberikan Simvastatin 10 mg/kgBB, dan kontrol normal tanpa perlakuan. Hasil penelitian ini menunjukkan pada kelompok kontrol positif menunjukkan penurunan kadar kolesterol total mencit yaitu 50.67± 35.82mg/dL, kontrol negatif menunjukkan penurunan kadar kolesterol hanya 2.67±1.89mg/dL, sedangkan pada kelompok normal (tanpa perlakuan) menunjukan peningkatan kadar kolesterol yaitu 6,66±4.70mg/dL. K1 menunjukan penurunan kadar kolesterol yaitu 51±36.06 mg/Dl, sementara K2 menunjukan penurunan kadar kolesterol sebesar 50.33±35.59 mg/dL, dan K3 menunjukan penurunan kadar kolesterol sebesar 86.67±61.28mg/dL. Berdasarkan hasil dari tiga kelompok tersebut menunjukkan adanya pengaruh dalam menurunkan kadarr kolesterol total pada mencit.
Monitoring of Medication Compliance in Type 2 Diabetes Mellitus Patients with Media Adherence Pill Box Unit Daily Dose Tresnowati, Gulita Indah; Kusuma, Ikhwan Yuda; Sunarti, Sunarti
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 14 No. 2 (2022): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (843.245 KB) | DOI: 10.35617/jfionline.v14i2.23

Abstract

Diabetes melitus (DM) merupakan suatu kelompok penyakit metabolik dengan karakteristik hiperglikemia yang terjadi karena kelainan sekresi affront, kerja affront atau kedua-duanya. Manajemen dan tatalaksana DM merupakan bagian dari asuhan kefarmasian untuk mengurangi penyebab ketidakpatuhan pasien dalam minum obat yang berakibat komplikasi. Salah satu cara untuk mencegah ketidakpatuhan adalah dengan menyediakan alat bantu berupa Adherence Pill Box Unit Every day Measurements. Tujuan dari penelitian ini adalah mengetahui pengaruh media Adherence Pill Box Unit Daily Dose dalam meningkatkan kepatuhan pengobatan pasien DM tipe 2. Penelitian ini menggunakan metode eksperimental dengan tipe one gather pre-post test plan. Information dianalisis menggunakan Wilcoxon rank test dari kuesioner MMAS- 8 mengenai kepatuhan pengobatan serta kadar gula darah sewaktu sebelum dan setelah diberikan Adherence Pill Box Unit Daily Dose. Hasil penelitian ini menunjukkan nilai skor MMAS – 8 nilai sig. 0.002 < 0.05, Kesimpulan dari penelitian ini adalah adanya pengaruh media Adherence Pill Box Unit Daily Dose dalam meningkatkan kepatuhan pengobatan pada pasien yang berpengaruh pada penurunan kadar glukosa darah sewaktu pasien DM tipe 2.
Preventive Health Behaviors Pada Caregiver Pasien Lansia Dan Hubungannya Dengan Kepatuhan Pengobatan Di Sulawesi Selatan Anggriani, A.; Rahmawati, Fita; Wahab, Izyan Abdul
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 13 No. 1 (2021): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (318.661 KB) | DOI: 10.35617/jfionline.v13i1.24

Abstract

Pasien lanjut usia atau geriatri rentan terhadap berbagai masalah klinis yang timbul akibat proses degeneratif dan berpengaruh dalam menjalankan kegiatan pribadi sehingga membutuhkan bantuan dari orang lain yang disebut caregiver. Seorang caregiver, selain membantu kegiatan pribadi pasien geriatri, juga berperan penuh dalam proses penyembuhan pasien. Hal ini dapat mengakibatkan caregiver akan memiliki beban mental yang harus diperhatikan agar proses caregiving pada pasien lanjut usia dapat berjalan dengan lancar. Penelitian ini dilakukan untuk mengidentifikasi aspek penguasaan emosional individu caregiver serta menelaah perannya dalam proses pengobatan pasien geriatri, terutama pada kepatuhan penggunaan obat. Penelitian ini menggunakan rancangan cross sectional yang melibatkan 131 responden. Pengumpulan data dilakukan melalui wawancara terhadap caregiver pasien usia lanjut yang mendapatkan layanan kesehatan di Puskesmas daerah Sulawesi Selatan. Instrumen kuesioner Pearlin Mastery Score digunakan untuk mengukur penguasaan emosional individu caregiver, dan pill count method untuk mengetahui tingkat kepatuhan pasien. Analisis data menggunakan statistik deskriptif terkait data demografi pasien dan caregiver serta Spearman-rho untuk mengetahui hubungan antar variabel. Hasil analisis menunjukkan angka koefisien korelasi sebesar 0,417** yaitu tingkat hubungan antara variabel penguasaan emosional caregiver terhadap tingkat kepatuhan pasien geriatri adalah sebesar 0,417 atau korelasi sedang dengan hubungan antar variabel searah dan bernilai signifikan (p<0,05). Semakin tinggi tingkat penguasaan emosional caregiver maka semakin tinggi tingkat kepatuhan pasien geriatri. Kata kunci: Geriatri, Caregiver, Preventive Health Behaviour, Kepatuhan Penggunaan Obat

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