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Al Makki Health Informatics Journal
Published by Al-Makki Publisher
ISSN : 30256518     EISSN : 30250501     DOI : -
Core Subject : Health,
Dentistry Health Professions Nursing Public Health Veterinary
l Makki Health Informatics Journal is an open-access scientific peer-review journal publishing. The Al Makki Health Informatics Journal focuses on exchanging information relating to intelligent computing and health informatics applied in industry, hospitals, government, and universities. All articles should include a validation of the idea presented, e.g. through case studies, experiments, or systematic comparisons with other approaches already in practice. Two types of papers are accepted: (1) A short paper that discusses a single contribution to a specific new trend or a new idea, and; (2) A long paper that provides a survey of a specific research trend using a systematic literature review (SLR) method, as well as a traditional review method. Topics of interest include, but are not limited to: Electronic health record E-Health Information Medical Image Processing & Techniques Data Mining in Healthcare Bioinformatics & Biostatistics Mobile applications for patient care Medical Image Processing & Techniques Hospital information systems Document handling systems Electronic medical record systems Standardization, and systems integration ICT in health promotion programmes e-health Guidelines and protocols E-learning & education in healthcare Telemedicine Software- Portals-Devices & Telehealth Public health & consumer informatics Data Mining & Knowledge Discovery in Medicine ICT for Patient empowerment ICT for Patient safety Medical Databanks-Databases & Knowledge Bases Healthcare Quality assurance Nursing Informatics Evaluation & Technology Assessment Home-based eHealth Health Management Issues Health Research Health Economics Issues Statistical Method for Computer Medical Decision Support Systems Medical Informatics or medicine in general Organizational, economic, social, clinical impact, ethical and cost-benefit aspects of IT applications in health care.
Arjuna Subject : Profesi Kesehatan - Terminologi Medis
Articles 81 Documents
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Normal Standards for Uric Acid, Blood Sugar, Blood Pressure, Body Mass Index as a Step to Control the Risk of Non-Communicable Diseases (NCDs) in the Kumelembuai Dua Village Community in South Minahasa Regency, North Sulawesi Province Rokot, Agus; M. Pandean, Marlyn; T. Watung, Agnes; T. Kawatu , Yozua
Al Makki Health Informatics Journal Vol. 3 No. 5 (2025): Al Makki Health Informatics Journal
Publisher : Al Makki Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/38rehb51

Abstract

Non-communicable diseases (NCDs) are often considered trivial and can trap humans due to ignorance within normal limits: uric acid, blood sugar, blood pressure, and body mass index, which can lead to disease. Abnormal conditions can trigger NCDs gradually but surely. These conditions, if not anticipated through symptom observation and control of normal levels, can cause death. The causes are diverse, including genetic factors and environmental influences such as diet, sleep, activity, and social environment. Data from Kumelembuai Village, South Minahasa Regency, North Sulawesi, shows that this research uses qualitative methods, following Basrowi & Suwandi (2014). Blood samples were taken in February-March 2025 to determine normal standards for uric acid, blood sugar, and BMI in adult men and women, mainly housewives, with a total of 72 respondents. The results show that women’s average uric acid level is 9.12 mg/dL, men’s 9.4 mg/dL; blood sugar averages are 98.02 mg/dL for women and 115.94 mg/dL for men; blood pressure averages are 135.34/79.21 mmHg for women and 151.56/80.25 mmHg for men; BMI averages are 26.46 for women and 24.75 for men. Overall, some values exceed normal thresholds, indicating a risk of NCDs. The conclusion is that these levels surpass standard normal limits and could lead to health issues. Early steps are necessary to prevent NCDs by paying attention to factors such as genetics, environmental influences, and lifestyle patterns, including eating, sleeping, activity, and social gatherings that may trigger the consumption of foods increasing disease risk.
Multisymptom Oral Presentation in Type II Diabetes Mellitus: A Case of Candidiasis, Xerostomia, and Burning Mouth Syndrome Shafia, Arina
Al Makki Health Informatics Journal Vol. 3 No. 5 (2025): Al Makki Health Informatics Journal
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/sbrbap90

Abstract

Background: Oral candidiasis is a fungal infection of the tongue and oral mucosa caused by Candida species, characterized by overgrowth and superficial tissue invasion. One of the main predisposing factors is an immunocompromised state such as type II diabetes mellitus. Fungal infections in diabetic patients may be associated with additional oral symptoms, including Burning Mouth Syndrome (BMS) and xerostomia. Case Presentation: A 53-year-old male presented with a three-day history of burning sensation localized to the left side of the tongue. The complaint had not been previously treated. The patient reported a reduced sense of taste, limited to salty and spicy sensations, and persistent dry mouth. Medical history revealed a diagnosis of type II diabetes mellitus for six years, with discontinuation of antidiabetic medication over the past three months. Management and Outcome: The treatment plan included chlorinated dioxide mouthwash (used three times daily), xylitol (taken three times daily), nystatin oral suspension (applied four times daily), a single dose of fluconazole 150 mg, and Becomzet (taken once daily). The patient was instructed to maintain strict adherence to the medication regimen, practice good oral hygiene, and attend regular follow-ups. Improvement in symptoms was observed after consistent use of the prescribed therapy. Conclusion: Effective management of oral candidiasis in patients with poorly controlled type II diabetes mellitus, particularly when accompanied by Burning Mouth Syndrome and xerostomia, requires a comprehensive treatment approach. Success is largely dependent on accurate drug selection and patient compliance with therapy and oral hygiene practices. This case highlights the importance of addressing systemic factors in conjunction with local treatment to ensure resolution of symptoms and prevent recurrence.
Efficacy and Safety of Acupuncture Compared with Standard Treatment in Migraine Without Aura: A Systematic Review of Randomized Controlled Trials Anggraini, Devanty; Albana, Rifki
Al Makki Health Informatics Journal Vol. 3 No. 5 (2025): Al Makki Health Informatics Journal
Publisher : Al Makki Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/4vxek311

Abstract

Introduction:Migraine without aura is a common neurological disorder that imposes a substantial global burden. While pharmacological therapy remains the cornerstone of treatment, limitations such as side effects, contraindications, and medication overuse highlight the need for complementary approaches. Acupuncture has been proposed as a potential alternative due to its neuromodulatory and analgesic effects. Methods: This systematic review followed PRISMA guidelines and the Cochrane Handbook for Systematic Reviews of Interventions. Searches were conducted in PubMed, ProQuest, SAGE Journals, and EuropePMC, including only randomized controlled trials comparing acupuncture with standard pharmacological treatments in migraine without aura. Outcomes of interest included headache frequency, intensity, acute medication use, quality of life, and safety. Risk of bias was assessed using the Cochrane RoB 2.0 tool. Results: Eight randomized controlled trials involving patients with migraine without aura were included. Acupuncture consistently reduced migraine frequency, with greater decreases in headache days and attack frequency compared with drugs such as flunarizine and valproic acid. Significant reductions in pain intensity were observed in several studies, with acupuncture showing either comparable or superior effects relative to pharmacological therapy. Acupuncture also led to earlier and more sustained reductions in acute medication use, potentially lowering the risk of medication overuse headache. Quality of life improvements were reported in domains of physical function, emotional well-being, and migraine-specific indices. Adverse events were generally mild and transient (e.g., local bleeding, discomfort), and occurred less frequently than with standard medications, which were associated with drowsiness, weight gain, or gastrointestinal symptoms. Discussion and Conclusion: Acupuncture demonstrates favorable efficacy and safety compared with standard pharmacological treatments in migraine without aura, offering reductions in frequency, intensity, and medication use, alongside improvements in quality of life. Given heterogeneity in protocols and some methodological limitations, further large-scale multicenter trials with standardized designs are warranted to confirm these findings and guide clinical practice.
The Role of the Four Pillars in Heart Failure with Reduced Ejection Fraction (HFrEF) and Heart Failure with Preserved Ejection Fraction (HFpEF): How Different? Wili Mahendra, Dentino
Al Makki Health Informatics Journal Vol. 3 No. 2 (2025): Al Makki Health Informatics Journal
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/hij.v3i2.49

Abstract

Heart failure (HF) remains a major clinical challenge, with two main phenotypes: heart failure with reduced ejection fraction (HFrEF) and heart failure with preserved ejection fraction (HFpEF). These conditions exhibit distinct pathophysiology, clinical manifestations, and therapeutic responses, requiring distinct management approaches. The four pillars of HFrEF therapy—renin-angiotensin system (RAS) inhibitors, β-blockers, mineralocorticoid receptor antagonists (MRAs), and sodium-glucose cotransporter-2 (SGLT2) inhibitors—have been shown to reduce mortality and morbidity. In contrast, HFpEF management focuses more on risk factor control and symptom-based therapy, with SGLT2 inhibitors being the only treatment that has shown significant clinical benefit. This literature review aims to evaluate the different roles of the four pillars of therapy in both phenotypes of heart failure and their implications for clinical practice. Although HFrEF treatment has made significant progress with strong clinical trial evidence, HFpEF management still requires further exploration to identify more effective strategies. Therefore, a deeper understanding of each phenotype's pathophysiology and therapeutic response is essential to improve patient outcomes and optimize heart failure management.
Antibacteria Susceptibility Test of Garlic (Allium sativum L.) Against Enterococcus faecalis As Root Canal Medicament Syaidah Ageng Kuswandi, Nabilla; Tarigan, Gita; Yuliadewi Rahmawati, Dicha
Al Makki Health Informatics Journal Vol. 3 No. 2 (2025): Al Makki Health Informatics Journal
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/hij.v3i2.50

Abstract

This study aims to investigate the effect of garlic extract (GE) on the inhibition of Enterococcus faecalis (EF) bacterial growth. This study is a laboratory experimental research with a true experimental post-test only control group design, conducted in vitro using the well diffusion method. The experimental group consists of EF bacteria treated with different concentrations of GE, while the control group consists of EF bacteria treated with 0.2% chlorhexidine (CHX) as the positive control (PC) and 10% dimethyl sulfoxide (DMSO) as the negative control (NC). This study aims to observe the inhibition zone diameter (IZD) of bacterial growth after treatment with different concentrations of GE or control agents, measured in millimeters using a caliper. Phytochemical test revealed that the GE used in this study contains secondary metabolite compounds such as phenolics, flavonoids, saponins, and steroids, resulting in an IZD of 5.85 ± 0.26 at 100% GE and 3.25 ± 0.27 at 75% GE. The IZD formed on PC was 17.34 ± 0.33, and no IZD was formed on 50% GE or NC. The effect of GE in inhibiting the growth of EF was observed by the presence of inhibition zones at 100% and 75% concentrations, although it was not yet able to match the effectiveness of 0.2% CHX.
A Pharmacogenomic Study to Predict Reverse Remodeling Afies, Mohammad
Al Makki Health Informatics Journal Vol. 3 No. 3 (2025): Al Makki Health Informatics Journal
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/hij.v3i3.51

Abstract

Cardiac remodeling refers to structural, functional, and molecular changes in the heart in response to stress or injury. These alterations, involving both cellular and interstitial changes, contribute to the progression of heart disease. Long-term activation of the autonomic nervous system (ANS) exacerbates these changes, leading to systemic vasoconstriction, sodium and water retention, and ventricular remodeling, which accelerates disease progression. Neurohormonal activation is essential in compensating for falling cardiac output in heart failure (HF), but it also plays a major role in the progression of the disease. This study explores the role of the renin-angiotensin-aldosterone system (RAA) and the sympathetic nervous system in cardiac remodeling, particularly in heart failure, and the influence of genetic factors on drug response. The research focuses on the ß2-Adrenergic Gln/Gln Receptor genotype, a key genetic variant relevant to pharmacogenomics in left ventricular hypertrophy (LVH) treatment. Using a comprehensive review of clinical and experimental data, this study highlights how genetic polymorphisms affect the pharmacokinetics and pharmacodynamics of drugs such as beta-blockers, ACE inhibitors, and ARBs. The findings indicate that while the ß2-Adrenergic Gln/Gln Receptor genotype significantly influences drug efficacy, the challenges in applying personalized treatments based on genetic data require significant time and cost investments. The study's implications emphasize the need for personalized therapies and enhanced pharmacogenomic research to improve treatment outcomes in heart failure management, particularly in drug response and disease progression.
The Effect of The Application of Head Coaching on The Work Motivation and Job Satisfaction of The Implementing Nurse at The Bandar Lampung Advent Hospital Gulo, Magdalena; Hastono, Sutanto Priyo; Wijayanti, Catharina Dwiana
Al Makki Health Informatics Journal Vol. 3 No. 3 (2025): Al Makki Health Informatics Journal
Publisher : Al Makki Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/hij.v3i3.52

Abstract

Nursing human resources today are experiencing a change in the generation of workers. The need for the role of the head nurse in carrying out coaching to support, collaborate, and facilitate nursing human resources of different generations in order to build effective working relationships, increase motivation, self-potential, and staff job satisfaction. The purpose of the study was to assess the impact of coaching training on nurses' motivation and job satisfaction. Quasi-experimental research design with one group pre-posttest design. Respondents in the research were implementing nurses, using questionnaire measuring tools. The results were obtained by the majority of respondents aged 20-30 years (42.9%), PK 2 career path (37.5%), nurse education (50.0%), and length of work 1-5 years (44.6%). Before the coaching training, the average motivation was 25.13 and job satisfaction was 23.73, while after the coaching training, the average motivation increased to 43 and job satisfaction increased to 35.98. The Paired Samples Test showed a significant effect of coaching training on motivation and job satisfaction with a p-value of 0.000, as well as an R square result of 0.838.  The need for the implementation of coaching by the head of the room to increase the motivation and work of nurses which will have an impact on the quality and effectiveness of nursing services.
Literature Review: Analysis and Validation of the Effectiveness of Antidiabetic Drugs in the Biological Matrix Using the HPLC (High Performance Liquid Chromatography) Method Aulia Fernanda, Syahwa; Tirsta Az-zahra, Naila; Savitri Setyoasih, Teresa; Najwa Akmila, Ghefira; Bekti Pertiwi, Sekar; Maharani, Sabrina
Al Makki Health Informatics Journal Vol. 3 No. 2 (2025): Al Makki Health Informatics Journal
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Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

High-Performance Liquid Chromatography (HPLC) is a widely used analytical method for the separation, identification, and quantification of compounds in complex biological matrices, such as plasma, serum, and urine. This article discusses the analysis and validation of the effectiveness of antidiabetic drugs using HPLC, focusing on sample preparation, column selection, mobile phase, and detectors used. Method validation is performed to ensure parameters such as specificity, linearity, precision, accuracy, limit of detection (LOD), and limit of quantification (LOQ) are met. Literature study from 18 journals showed that HPLC is a sensitive, specific, and efficient method for antidiabetic drug analysis. Preparation techniques such as protein precipitation and solid-phase extraction provide optimal results in minimizing biological matrix interferences. In addition, the Photodiode Array (PDA) detector proved superior in terms of sensitivity and analyzability at low concentrations compared to other detectors. By fulfilling all validation parameters, HPLC can be relied upon as a primary method for the analysis of antidiabetic drugs in biological matrices.
Hyperosmolar Hyperglycemic State (HHS) and Diabetic Kidney Disease (DKD) as Acute and Chronic Complications of Type 2 Diabetes Mellitus in End-Stage Chronic Kidney Disease (CKD): a Case Report Premaiswari Suparthika, Ni Putu Radha; Sutarka , Nyoman
Al Makki Health Informatics Journal Vol. 3 No. 3 (2025): Al Makki Health Informatics Journal
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/hij.v3i3.54

Abstract

Introduction: Hyperosmolar hyperglycemic state (HHS) is a life-threatening condition that often occurs in patients with type 1 and 2 diabetes mellitus characterized by hyperglycemic crises, hyperosmolarity, dehydration, with mild ketosis or no eketosis. Another chronic complication of Diabetes Mellitus is Diabetic Kidney Disease (DKD). Ni Putu Radha Premaiswari Suparthika1, I Nyoman Sutarka. Case Presentation: A 61-year-old male patient was referred with decreased consciousness since 5 days of SMRS. The patient has a history of type 2 diabetes mellitus since 20 years. In patients, signs were obtained in the form of decreased consciousness, severe hyperglycemia of 680 mg/dL, hyperosmolarity of 360 mOsm/kg, increase in anion gap >12, UTI complications as the trigger of HHS. In patients, moderate anemia was also found normochromic-normocyter, massive proteinuria, and decreased kidney function. Conclusion: In the 61-year-old male patient described in this case report, there are acute and chronic complications of Diabetes Mellitus that occur simultaneously and have caused high morbidity and mortality in patients.
The Relationship Between Stress And Adolescent Academic Perception Ability Based On Gender And Body Mass Index Alfiandari, A. Dhini; Ichsan, Rayhani; Aminuddin, Nurul Mutiah; Damry , Nurul Muf’idah
Al Makki Health Informatics Journal Vol. 3 No. 3 (2025): Al Makki Health Informatics Journal
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Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/hij.v3i3.55

Abstract

Stress in adolescents has the potential to impact various aspects of physical and mental health, including perceived academic ability. Differences in gender and nutritional status such as body mass index (BMI) can affect stress levels and academic perception abilities in adolescents. Objective: To assess the relationship between stress and academic perception abilities based on gender and BMI in high school-aged adolescents. Methods: An observational analytical study with a cross-sectional approach was conducted on 53 students aged ≤18 years at SMAN 2 Parepare. Data were collected through an online questionnaire using the Indonesian version of the PSS-10 instrument and the TASES scale. BMI was calculated from weight and height. Data were analyzed using the t-test, ANOVA, and Pearson correlation. Results: There were no significant differences in stress scores or academic perception abilities based on gender and BMI category (p>0.05). There was no significant relationship between stress and academic perception abilities (r=–0.02; p=0.901). Conclusion: Gender and BMI status do not significantly influence stress and academic perception abilities. Other factors such as coping strategies and social support need further investigation.

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