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Andri Putra Kesmawan
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INDONESIA
Health & Medical Sciences
Published by Indonesian Journal Publisher
ISSN : -     EISSN : 30263867     DOI : https://doi.org.10.47134/phms
Core Subject : Health,
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health
Pubmedia Health & Medical Sciences uses an online submission and peer review platform, which allows authors to track the progress of their manuscript and enables shorter processing times. Amidst the trend in attempting to constantly provide answers in problems or phenomena in our reality for a better health condition, Pubmedia Digital Series strive to publish a factual and applicable research result through the publication of journals from a wide arrange of field of studies such as in medicine, pharmacy, biology and the like. Focus and Scope Physiology Pharmacology Toxicology Genetics Neuroscience Tissue Engineering Regenerative Medicine Hematology Immunology Oncology Dentistry
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 110 Documents
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Rationality of Drug Administration in Patients with Diabetes Mellitus at Royal Prima Hospital Medan Lubis, Graida Tsuraiya; Simanjuntak, Nerly Juli Pranita; Razoki
Health & Medical Sciences Vol. 2 No. 4 (2025): August
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v2i4.436

Abstract

Acute and chronic diseases caused by poor lifestyle choices or genetics are becoming more common over time and do not seem to be decreasing each year.  This study aims to determine whether the treatment of type 2 diabetes mellitus patients with or without hypertension at Royal Prima Medan Hospital is appropriate.  Descriptive research methodology, namely cross-sectional data, was used in this study.  Retrospective data collection was conducted using information from medical records at one of the Royal Prima Medan University Hospitals from November 2023 to April 2024. Based on 93 medical records, the findings showed that the right drug, right indication, and right dose were all 100% rational.  Moderate drug interactions accounted for 67% of all drug interactions, major interactions 18%, and minor interactions 15%.  In conclusion, Royal Prima University Hospital in Medan had 100% rational medical data for the period November 2023-April 2024.
Efektivitas Intervensi Psikoedukasi dalam Mengurangi Gejala Postpartum Blues Meidora, Alfiani Hana; Purnamawati, Dewi
Health & Medical Sciences Vol. 2 No. 4 (2025): August
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v2i4.447

Abstract

Postpartum blues adalah gangguan emosional awal yang umumnya terjadi pada ibu pascapersalinan dan, jika tidak ditangani, dapat berkembang menjadi depresi pascapersalinan. Ketidakstabilan emosi, kelelahan, dan kurangnya dukungan sering kali memperparah kondisi ini. Psikoedukasi dianggap sebagai salah satu intervensi non-farmakologis yang efektif untuk meningkatkan kesadaran dan mekanisme koping ibu dalam menghadapi masa transisi pascapersalinan. Penelitian ini menggunakan desain quasi eksperimental dengan pendekatan kelompok kontrol pre-test dan post-test. Populasi penelitian adalah ibu nifas hari ke-3 sampai hari ke-10 di wilayah kerja dua puskesmas. Sebanyak 60 ibu nifas dipilih dengan menggunakan purposive sampling, dibagi rata menjadi kelompok intervensi dan kelompok kontrol. Intervensi yang diberikan berupa sesi psikoedukasi yang mencakup perubahan emosi setelah melahirkan, manajemen stres, dan peran dukungan sosial. Data dikumpulkan dengan menggunakan Edinburgh Postnatal Depression Scale (EPDS) yang telah dimodifikasi. Analisis statistik dilakukan dengan menggunakan uji-t berpasangan dan uji-t independen. Mayoritas responden berusia 20-35 tahun (88,3%), multipara (56,7%), berpendidikan menengah (63,3%), dan merupakan ibu yang tidak bekerja (71,7%). Pasca intervensi, rata-rata skor postpartum blues menurun secara signifikan pada kelompok intervensi (p <0,05), sementara tidak ada perubahan signifikan pada kelompok kontrol. Terdapat pengaruh yang signifikan secara statistik dari intervensi psikoedukasi dalam mengurangi gejala postpartum blues pada ibu pasca melahirkan. Integrasi intervensi ini ke dalam perawatan postpartum standar direkomendasikan untuk meningkatkan kesehatan mental ibu.
Studi Farmakodinamik Infusa Daun Mimba dan Daun Nangka sebagai Kandidat Antipiretik Alami pada Tikus putih galur Wistar Haryanto; Astuti, Sri; Azzahra, Andi; Damayanti, Arfina; Aulia, Besse; Nurdiake, Besse; Ahmad, Najwa; Zulkifli; Putri, Ulfa
Health & Medical Sciences Vol. 2 No. 4 (2025): August
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v2i4.453

Abstract

Demam merupakan kondisi yang umum diatasi dengan sediaan antipiretik, namun penggunaan obat sintetik secara berlebihan dapat menimbulkan resistens, serta gangguan fungsi hati, sehingga diperlukan alternatif dari bahan alami. Penelitian ini bertujuan untuk mengevaluasi dan membandingkan efek antipiretik dari berbagai sediaan obat baik sintetik maupun herbal terhadap tikus putih (Rattus norvegicus) yang telah diinduksi demam. Penelitian dilakukan di Laboratorium Farmakologi dan Toksikologi FKIK Universitas Muhammadiyah Makassar. Induksi demam dilakukan menggunakan larutan pepton 5% secara intraperitoneal, kemudian hewan uji diberikan perlakuan berupa paracetamol, ibuprofen, natrium diklofenak, ekstrak daun nangka, ekstrak daun mimba, serta Na-CMC sebagai kontrol negatif. Suhu tubuh diukur melalui rektal secara berkala setiap 30 menit selama 2,5 jam. Data dianalisis menggunakan perangkat lunak SPSS melalui uji normalitas dan homogenitas. Hasil menunjukkan bahwa ibuprofen, paracetamol, infusa daun nangka, dan daun mimba secara berurutan memberikan penurunan suhu yang cukup signifikan dibandingkan sediaan lain, natrium diklofenak menunjukkan efektivitas yang lebih rendah. Na-CMC sebagai kontrol tidak memberikan efek antipiretik yang berarti. Namun demikian, hasil analisis statistik menunjukkan bahwa terdapat perbedaan efek yang signifikan antar kelompok perlakuan (nilai signifikansi < 0,05). Sedangkan uji lanjutan menunjukkan hasil yang nonsignifikan antara perlakuan obat ibuprofen, paracetamol, infusa daun nangka dan daun mimba yang berarti bahwa kedua sediaan infusa memiliki efek antipiretik.
Characteristics of External Respiratory System Parameters in School-Age Children under the Environmental Conditions of the Republic of Karakalpakstan Sevaraxon, Masharipova
Health & Medical Sciences Vol. 2 No. 4 (2025): August
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v2i4.456

Abstract

This study is  aimed at assessing the indicators of the external respiratory system in school-aged children living under the environmental conditions of the Republic of Karakalpakstan. A cross-sectional observational study was conducted involving 300 children aged 7 to 14, using spirometry to measure lung vital capacity (VLC) and peak expiratory flow rate (PEFR), pulse oximetry to assess blood oxygen saturation (SpO₂), and structured questionnaires to collect data on environmental and behavioral factors. The results showed that around 60% of the participants had reduced VLC and PEFR, and the average SpO₂ was 95%, indicating early signs of respiratory dysfunction. Environmental factors, such as high levels of dust and agrochemical use, were significantly correlated with reduced respiratory function. Furthermore, climatic conditions like low humidity and temperature fluctuations exacerbated these effects. Social and behavioral factors, including low physical activity and poor nutrition, were also linked to respiratory impairment. Comparative analysis with other Central Asian regions revealed a 15–20% higher prevalence of respiratory disorders among Karakalpak children. The findings highlight the urgent need for preventive interventions, including enhanced air quality monitoring, promotion of physical activity, improved nutrition, and regular medical screenings. These measures are essential to reduce the risk of chronic respiratory diseases and improve long-term health outcomes for children in environmentally vulnerable areas.
Hubungan Layanan Petugas Laboratorium terhadap Kepuasan Pasien Rawat Jalan di Laboratorium Patologi Klinik Rsud Dr Kanujoso Djatiwibowo Anisa, Rifka; Parwati, Putu; Andini, Ns.
Health & Medical Sciences Vol. 2 No. 4 (2025): August
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v2i4.461

Abstract

Kualitas layanan laboratorium merupakan faktor penting dalam menentukan kepuasan pasien. Pelayanan laboratorium yang baik dipengaruhi oleh waktu tunggu, sikap, dan keterampilan petugas, yang secara langsung berdampak pada kepuasan pasien. Penelitian ini bertujuan untuk mengetahui hubungan antara layanan petugas laboratorium, yang meliputi waktu tunggu, sikap, dan keterampilan, terhadap kepuasan pasien rawat jalan di Laboratorium Patologi Klinik RSUD Dr. Kanujoso Djatiwibowo. Penelitian ini menggunakan pendekatan kuantitatif dengan metode survei dan melibatkan 282 responden yang dipilih menggunakan teknik accidental sampling. Data dikumpulkan melalui kuesioner dan dianalisis secara statistik. Hasil penelitian menunjukkan bahwa 88,65% responden menilai waktu tunggu pelayanan sudah tepat (≤140 menit), 97,87% menyatakan puas terhadap sikap petugas, dan 98,23% menilai keterampilan petugas sangat baik. Tingkat kepuasan pasien juga tinggi pada seluruh dimensi yaitu: tangible (81,9%), reliability (78,4%), responsiveness (76,2%), assurance (79,1%), dan empathy (77,3%). Uji Spearman menunjukkan terdapat hubungan signifikan antara waktu tunggu (p = 0,000; r = 0,636), sikap petugas (p = 0,000; r = 0,684), dan keterampilan petugas (p = 0,000; r = 0,674) terhadap kepuasan pasien. Hasil ini mengindikasikan bahwa semakin baik layanan yang diberikan oleh petugas laboratorium, semakin tinggi pula tingkat kepuasan pasien. Penelitian ini memberikan masukan penting bagi manajemen rumah sakit untuk terus meningkatkan mutu layanan laboratorium guna menciptakan pengalaman pasien yang positif.
Evidence-Based Management Approach In Health Service Policy Decision-Making At Clinic of Plantation Company X Hidayat, Asep; Wardani, Ratna; Agustin
Health & Medical Sciences Vol. 2 No. 4 (2025): August
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v2i4.460

Abstract

The research comprehensively examines the application of Evidence-Based Management (EBMgt) in decision-making for health service policies at Clinic of Plantation Company X. The main focus is on the influence of six types of evidence: Scientific and Research Evidence, Hospital Facts and Information, Political-Social Development Plans, Professional Managerial Expertise, Ethical-Moral Evidence, and Stakeholder Values and Expectations on policy decisions in the clinic. This study uses a quantitative method with a Structural Equation Modeling (SEM) approach based on Partial Least Squares (PLS). Data were collected through structured questionnaires from 110 respondents comprising managers and decision-makers at the clinic. Instrument validity and reliability were tested before conducting the measurement and structural model analysis. The findings show that all six evidence dimensions significantly affect policy decision-making (p < 0.05). The measurement model met convergent and discriminant validity criteria with AVE and composite reliability values above 0.70. Integrating these evidence dimensions enhances the quality, effectiveness, and accountability of managerial decisions at the clinic. The research highlights the importance of a holistic EBMgt approach combining empirical data, professional expertise, and ethical-social aspects to support effective and responsible policy decisions in healthcare services. The study recommends strengthening the use of multiperspective evidence in clinic policy management to achieve better and sustainable service outcomes.
Hubungan Pengetahuan Ahli Teknologi Laboratorium Medis Terhadap Perilaku Penggunaan Alat Pelindung Diri Di Rumah Sakit Kota Sangatta Santi, Rasmiati; Ni Luh Gede Puspita Yanti; Nyoman Sudarma
Health & Medical Sciences Vol. 2 No. 4 (2025): August
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v2i4.457

Abstract

Laboratorium merupakan tempat kerja dengan tingkat resiko bahaya tinggi karena melibatkan bahan-bahan kimia yang berbahaya. Tujuan penelitian untuk mengetahui hubungan tingkat pengetahuan ahli teknologi laboratorium medis terhadap perilaku penggunaan APD di Rumah Sakit Kota Sangatta. Metode penelitian ini adalah deskriptif korelasional dengan melibatkan seluruh Ahli Tenaga Laboratorium rumah sakit se-kota Sangatta sebagai responden. Instrumen penelitian menggunakan kuisioner yang berisi pernyataan terkait pengetahuan dan perilaku penggunaan APD. Data hasil penelitian diperoleh sebagian besar dengan pengetahuan tinggi yaitu 48 (85,8%) responden dan perilaku penggunaan APD baik sebanyak 29 (52,2%) responden. Dengan hasil yang di dapat pada uji Chi Square 0,465; α=0,05 menunjukan pengetahuan Ahli Teknologi Laboratorium Medik terhadap APD tidak ada hubungan yang signifikan antara tingkat pengetahuan dengan perilaku penggunaan APD. Hasil uji statistik menyatakan bahwa tidak ada hubungan diantara keduanya. Tingginya tingkat pengetahuan Ahli Teknologi Laboratorium Medis tentang APD ternyata tidak sejalan dengan peningkatan perilaku penggunaan APD dengan baik
Effect of Traditional and Commercial Yoghurt Consumption on Blood Glucose Levels in Young Adults S. Ajil , Anwar; M. Ali , Alyaa; J. Jaber , Hiba; S. Najem , Noor; F. Mzael , Noura; Marzouk, Alaa; Al-Salhi, Ahmed; Al-Shatty, Sabah
Health & Medical Sciences Vol. 2 No. 4 (2025): August
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v2i4.471

Abstract

This study aimed to evaluate traditionally fermented yoghurt in comparison with selected commercially imported brands in Iraq (Kalleh, Pegah, Ramak), focusing on their chemical, microbiological, and physiological characteristics. The analyses included qualitative detection of starch and lactose, pH measurement, enumeration of lactic acid bacteria, and assessment of postprandial glycemic responses in healthy young adults over four weeks. The findings demonstrated that commercial yoghurts contained residual starch and lactose, attributable to the addition of thickening agents and the incomplete utilisation of lactose resulting from the inactivation of viable bacteria by heat treatment or irradiation. In contrast, traditional fermented yoghurt was free of such residues and exhibited significantly higher counts of active bacteria, which contributed to a notable decrease in pH during storage. From a physiological perspective, consumption of traditional yoghurt was associated with the lowest glycemic response, with peak blood glucose reaching 110 mg/dL and returning rapidly to baseline levels (95–100( mg/dL. Conversely, commercial yoghurts produced higher glycemic peaks ranging from )130 – 138( mg/dL, reflecting their higher simple sugar content and variations in processing methods. Such pronounced glycemic elevations may place additional strain on pancreatic β-cells and, if consumed regularly, could increase the risk of insulin resistance.
Evaluation of Good Distribution Practice (GDP) Implementation at the Provincial Pharmacy and Health Logistics Installation (IFLK) of Riau Nofriyanti; Devi Safitri; Nurzakyya Tinnisa; Ramona, Paula
Health & Medical Sciences Vol. 2 No. 4 (2025): August
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v2i4.495

Abstract

This study aimed to evaluate the implementation of Good Distribution Practice (GDP) at the Provincial Pharmacy and Health Logistics Installation (IFLK) of Riau. The research employed direct observation, document review, and active participation in pharmaceutical management activities, including planning, procurement, storage, distribution, recording, and monitoring. The evaluation focused on three key areas: general drug management, cold chain products, and controlled substances such as narcotics and psychotropics. The results showed that all assessed aspects of GDP were properly implemented at IFLK Riau, including the application of FIFO and FEFO principles, well-maintained cold chain facilities, secure storage for controlled drugs, and systematic stock documentation. Overall, the implementation of GDP at IFLK Riau was considered optimal and compliant with national standards, ensuring the quality, safety, and availability of medicines within the region. These findings emphasize the critical role of pharmacists in maintaining the integrity and sustainability of the pharmaceutical distribution system.
Leafy Vegetables as Natural Sources of Minerals and Vitamins and Their Role in Human Health: A Review Alhafadhi, Arshed; Alnassrallah, Rakhaa; Alobaidi, Ahmed; Almansarawi, Ali; Alshemari, Nada; Al-Salhi, Ahmed Ali Al-Salhi; Al-Shatty, Sabah
Health & Medical Sciences Vol. 2 No. 4 (2025): August
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/phms.v2i4.498

Abstract

This review aims to assess the nutritional composition and health-promoting effects of selected leafy green vegetables—celery, basil, arugula, garden cress, and radish—and their potential contribution to preventing chronic diseases. Recent scientific evidence (2020–2025) was analyzed from clinical, epidemiological, and biochemical studies highlighting the physiological effects of these vegetables. The review methodology focused on identifying bioactive compounds, including nitrates, flavonoids, vitamins, and minerals, and evaluating their effects on key health outcomes such as cardiovascular performance, metabolic regulation, and digestive function. Results indicate that regular consumption of nitrate-rich leafy vegetables significantly contributes to lowering blood pressure, improving vascular elasticity, and reducing oxidative stress. Bioactive components such as flavonoids and polyphenols enhance lipid metabolism, decrease LDL cholesterol, and support antioxidant defense systems. Furthermore, dietary fiber and phytochemicals from arugula, celery, and basil positively influence gut microbiota composition and intestinal health, while compounds in radish and garden cress demonstrate glucose-regulating and anti-inflammatory properties.Overall, incorporating a diverse range of leafy green vegetables into daily diets serves as an effective, low-cost nutritional strategy to improve cardiovascular, metabolic, and digestive health. The findings underscore the need for further controlled clinical trials to determine optimal intake levels, synergistic effects among different species, and precise biochemical pathways underlying these health benefits.

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