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Nanang Khosim Azhari
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Jurnal Ventilator: Jurnal Riset Ilmu Kesehatan dan Keperawatan
Published by Sekolah Tinggi Ilmu Kesehatan Kesdam IV, Diponegoro
ISSN : 2986786X     EISSN : 29867088     DOI : 10.59680
Core Subject : Health,
Health Professions Nursing Public Health
Bidang kesehatan dan keperawatan termasuk penelitian dasar dalamkesehatan dan keperawatan, keperawatan manajemen, keadaan darurat, dan keperawatan kritis, keperawatan medis-bedah, keperawatan kesehatan mental, keperawatan maternitas, keperawatan Anak, gerontologis keperawatan, keperawatan komunitas, keperawatan pendidikan keperawatan keluarga, pengobatan komplementer dan alternatif (CAMs, Complementary and alternative medicines) dalam keperawatan.
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 426 Documents
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Efek Minuman Ringan Berkarbonasi terhadap Struktur Histopatologi Ginjal pada Tikus Putih Jantan (Rattus Norvegicus) Inne Fioren Monica; Hasna Dewi; Raihanah Suzan; Fairuz Quzwain; Zahra Frizki Asty
Jurnal Ventilator Vol. 4 No. 3 (2026): September : Jurnal Ventilator
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/ventilator.v4i3.2715

Abstract

Consumption of carbonated soft drinks continues to increase in Indonesia. These beverages contain high levels of fructose, phosphoric acid, and various additives that may induce kidney damage through oxidative stress and metabolic dysfunction. This study aimed to evaluate the effects of carbonated soft drink administration at different doses on the renal histopathological structure of male white rats (Rattus norvegicus). This experimental study involved 24 male Wistar rats divided into four groups: a negative control (distilled water), treatment 1 (3 mL/day), treatment 2 (7 mL/day), and treatment 3 (10 mL/day) for 30 days. Renal histopathological examination was performed using hematoxylin–eosin staining at 400× magnification. Data were analyzed using the Kruskal Wallis test followed by the Post Hoc Mann-Whitney test. Significant differences in renal histopathological changes were observed between the control group and all treatment groups (p < 0.001). The observed changes included inflammatory cell infiltration, Bowman’s space edema, and tubular epithelial cell swelling. However, no significant differences were found among the treatment groups (p > 0.05). These findings indicate that carbonated soft drinks can induce renal histopathological changes even at the lowest dose, although increasing the dose did not produce a linear dose–response relationship.
Review Artikel: Drug Related Problems pada Penyakit Kronis: Implikasi Klinis dan Upaya Intervensi Nadira Khaerunnisa; Wulan Desi Rahmayanti; Anisa Zanuba; Zilfia Rahayu; Ditha Zanetti Octavia; Tuhfatul Ulya
Jurnal Ventilator Vol. 4 No. 3 (2026): September : Jurnal Ventilator
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/ventilator.v4i3.2720

Abstract

Chronic diseases such as type 2 diabetes mellitus, hypertension, asthma, and chronic kidney disease require long-term therapy that often involves multiple medications, increasing the risk of Drug Related Problems (DRPs). This review article summarizes patterns of DRPs and the contributing factors based on recent studies. The findings indicate that common DRPs include inappropriate dosing, drug interactions, drug use without indication, untreated indications, and ineffective therapy. In chronic kidney disease, DRPs frequently arise from inadequate dose adjustment in response to declining renal function, while in asthma, suboptimal medication use and incorrect inhaler technique are dominant causes. Overall, DRPs negatively affect therapeutic outcomes, increase the incidence of adverse effects, and elevate the risk of complications. Therefore, pharmacist-led interventions such as regular medication reviews, counseling, dose adjustment, and patient education are essential to prevent DRPs and improve treatment safety and effectiveness in chronic disease management.
Hubungan Aktivasi Pasien dengan Perilaku Self-Management Diet Cairan pada Pasien Penyakit Ginjal Kronis yang Menjalani Hemodialisis Fitri Adella; Rizqa Wahdini; Nia Rosliany
Jurnal Ventilator Vol. 4 No. 3 (2026): September : Jurnal Ventilator
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/ventilator.v4i3.2740

Abstract

Chronic kidney disease requires patients undergoing hemodialysis to adhere to fluid and dietary self-management in order to maintain their health condition. Patient activation is considered an important factor in improving patients’ ability to independently manage their health. This study aimed to analyze the relationship between patient activation and fluid diet self-management among patients with chronic kidney disease undergoing hemodialysis at Husada Hospital, Jakarta. A correlational analytic method with a cross-sectional design was used, involving 124 respondents selected through purposive sampling. Data were collected using the Patient Activation Measure-13 (PAM-13) and the Fluid Control in Hemodialysis Patients Scale (FCHPS). The data were analyzed using the Spearman Rank Correlation test. The results showed that 93.5% of respondents had good patient activation, while 75.8% demonstrated good fluid diet self-management. Statistical analysis revealed a significant positive relationship between patient activation and fluid diet self-management (p < 0.001; r = 0.326). These findings indicate that higher patient activation is associated with better fluid diet self-management among chronic kidney disease patients undergoing hemodialysis.
Pengaruh Terapi Intradialysis Exercise terhadap Terjadinya Kram Otot Pasien Hemodialisis di Ruang Hemodialisa RS BaliMed Denpasar Ni Made Thania Apriliawati; Komang Yogi Triana; Ni Luh Putu Dian Yunita Sari
Jurnal Ventilator Vol. 4 No. 3 (2026): September : Jurnal Ventilator
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/ventilator.v4i3.2742

Abstract

Muscle cramps are a common complication experienced by patients undergoing hemodialysis, resulting from changes in fluid balance, electrolytes, and muscle perfusion. This condition causes pain and discomfort and compromises the adequacy of hemodialysis, necessitating effective non-pharmacological interventions such as intradialysis exercise. This study aimed to determine the effect of intradialysis exercise therapy on the occurrence of muscle cramps in hemodialysis patients at the Hemodialysis Unit of BaliMed Hospital, Denpasar. A pre-experimental design specifically a one-group pretest-posttest design was employed. The study sample consisted of 23 respondents selected via purposive sampling. Muscle cramp severity was measured using the Cramp Questionnaire Chart before and after the intradialysis exercise intervention. Data were analyzed using the Wilcoxon Signed-Rank Test. The results showed that prior to the intervention, the majority of respondents experienced moderate muscle cramps, whereas after the intervention, most respondents did not experience muscle cramps. The Wilcoxon Signed-Rank Test yielded a p-value of 0.001 (p<0.05), thus it can be concluded that intradialysis exercise therapy has a significant effect on reducing the incidence of muscle cramps among hemodialysis patients at the Hemodialysis Unit of BaliMed Hospital, Denpasar.
Association of Polypharmacy and Drug-Related Problems with Quality of Life in Hypertensive Patients with Comorbidities Kartini Hasballah; Zaki Mubarak; Heldi Candra; Fifin Oktaviani
Jurnal Ventilator Vol. 3 No. 2 (2025): Jurnal Ventilator
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/ventilator.v3i2.2811

Abstract

Hypertension frequently coexists with comorbidities such as type 2 diabetes, dyslipidaemia, and chronic kidney disease. That mix produces polypharmacy and raises the risk of drug-related problems (DRPs), which in turn can erode quality of life (QoL). This study set out to examine the relationship between polypharmacy, DRPs, and QoL in hypertensive patients with comorbidities. An observational cross-sectional study was carried out at the outpatient internal medicine clinic of X Hospital, Batam, from January to June 2024. Consecutive sampling yielded 130 patients meeting the inclusion criteria. Polypharmacy was defined as the concurrent use of five or more medications. DRPs were classified with the Pharmaceutical Care Network Europe (PCNE) V9.1 tool, Bahasa Indonesia version. QoL was measured using the validated Indonesian SF-36 questionnaire. Data were analysed with Spearman rank correlation and multivariate logistic regression. Polypharmacy was present in 63.1% of patients, and DRPs were identified in 76.2%, most commonly drug interactions (31.4%) and dose-selection issues (24.8%). Polypharmacy correlated negatively with total QoL scores (r = -0.542; p < 0.001), as did DRPs (r = -0.418; p < 0.001). Multivariate analysis confirmed polypharmacy (AOR 3.24; 95% CI 1.62-6.48) and DRPs (AOR 2.87; 95% CI 1.41-5.85) as independent predictors of poor QoL. Integrated pharmaceutical care with an explicit focus on medication review is critical for mitigating DRPs and improving QoL in this population.
Analisis Kebutuhan Tempat Tidur Tersedia untuk Implementasi Kelas Rawat Inap Standar (KRIS-JKN) di Rumah Sakit Bhayangkara Tk. I Pusdokkes Polri Leny Malinda; Mieke Nurmalasari; Hozisah Hozisah; Witri Zuama Qomarania
Jurnal Ventilator Vol. 4 No. 3 (2026): September : Jurnal Ventilator
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/ventilator.v4i3.2719

Abstract

The implementation of Kelas Rawat Inap Standar (KRIS) within the Jaminan Kesehatan Nasional (JKN) program requires hospital readiness, particularly in meeting efficient and standardized inpatient bed capacity. This study aims to analyze trends in bed utilization and forecast inpatient bed requirements as a basis for planning KRIS-JKN implementation. This research employs a quantitative method to calculate bed requirements and a qualitative approach to assess readiness for KRIS-JKN implementation at Rumah Sakit Bhayangkara Tk.I Pusdokkes Polri. The data used are secondary data obtained from inpatient recapitulation reports from the Medical Record Unit during the period 2022–2025, including the number of available beds, number of discharged patients, and total inpatient days. The research utilized Tableau Public with a data mining approach following the CRISP-DM (Cross Industry Standard Process for Data Mining) framework. The results present forecasting of bed requirements using BOR scenarios of 60%, 70%, and 80%. The forecasts show that for January–March 2026, bed requirements range from 233–347 units for Class I, 78–146 units for Class II, and 250–487 units for Class III. These findings provide a basis for hospital planning to support efficient and standardized KRIS-JKN implementation.

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