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CERATA
Published by Universitas Muhammadiyah Klaten
ISSN : 20891458     EISSN : 26851229     DOI : https://doi.org/10.61902/cerata
Core Subject : Health,
Medicine & Pharmacology
Its Journal covers a lot of common problems or issues related to the Pharmaceutical sciences, including Pharmacetics, Biopharmacy, Drug Delivery Systems, Pharmaceutical Physics, Pharmaceutical Chemistry, Pharmaceutical Technology, Pharmaceutical Biotechnology and Microbiology, Pharmacology and Toxicology, Pharmacokinetics, Clinical and Community Pharmacy, Pharmaceutical Regulation and Marketing, Herbal Medicine.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 103 Documents
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Penetapan Kadar Asam Lemak Bebas (Alb) Pada Minyak Goreng Kemasan Dan Minyak Goreng Curah Dengan Perlakuan Berdasarkan Lama Waktu Pemanasan Khoirul Mahmudah; Vivin Nopiyanti
CERATA Jurnal Ilmu Farmasi Vol 10 No 1 (2019): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v10i1.67

Abstract

Cooking oil is one of the ingredients needed by the community, especially house wives and made from oi lpalm. Free fatty acids are not separated from cooking oil which causes bad effects on humans. This study aims to determine the levels of free fatty acids (FFA) in packagedcookingoilandbulkcookingoilbytreatmentbasedonheatingtime .This study uses the sample used in this study, bulk cooking oil taken from the markets of Mojosongo, Surakarta and 3 samples of packaged cooking oil which are sold in Surakarta Supermarket in January 2019. This research method uses acid base titration. The time used for analysisis 0 ', 15', 30 ', 45', 60 ', 75'at 160 and compares the levels with the Cooking Oil Quality Standards .The results of this study indicate the levels of free fatty acids in cooking oil, sample A heating to 0,1,2,3 was 0,16%; 0,20%; 0,22%; 0,25% according to SNI while heating to 4, 5 was 0,33%; 0,40% did not meet SNI standards. Sample B warmed up to 0,1,2,3,4,5 which were 0,12%; 0,14%; 0,15%; 0,17%; 0,21%; 0,24%, Sample C warmed up to 0,1,2,3,4,5 which were 0,12%; 0,16%; 0,19%; 0,21%; 0,22%; 0,24%; Sample D warms up to 0,1,2, 3,4,5 whichwere 0,12%; 0,14%; 0,16%; 0,18%; 0,21%; 0,24% according to the Cooking Oil Quality Standards.
Analisis Logam Merkuri (Hg) dalam Krim Pemutih Herbal Temulawak (Curcuma zanthorrhiza) dengan Metode Mercury Analyzer Anita Agustina Styawan; Lenny Apriyaningsih; Dwi Joko Yulianto
CERATA Jurnal Ilmu Farmasi Vol 10 No 1 (2019): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v10i1.68

Abstract

Temulawak herbal whitening cream is one of the herbal whitening creams containing curcumin rhizome extract containing curcumin, demetoksikurkumin and bidemetoksikurkumin which can reduce hyperpigmentation (the skin becomes too dark). Mercury is a dangerous metal that in even small concentrations can be toxic. The use of mercury in whitening creams can cause a variety of things, ranging from changes in skin color which will eventually cause black spots on the skin, allergies, skin irritation and can be carcinogenic. The results of the study qualitatively indicated that sample A was positive containing mercury marked by an orange-red precipitate. Quantitatively, using Mercury Analyzer in sample A, the levels of mercury were 7,470.52 mg / kg or 7,470.52 ppm. The conclusions indicate that sample A is inappropriate or should not be used because it contains more than 1 mg / kg or 1 ppm of mercury.
Penetapan Kadar Formalin Pada Tahu Di Pasar X Dengan Metode Spektrofotometri Visible Nanik Fitrianingsih; Choiril Hana Mustofa; Sunyoto
CERATA Jurnal Ilmu Farmasi Vol 10 No 1 (2019): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v10i1.69

Abstract

Tofu is a food product in the form of soft solids made through soy processing. Formalin is a clear liquid that is colorless or almost colorless with a pungent odor, its vapors stimulate the mucous membranes of the nose and throat, formalin is a dangerous, poisonous and carcinogenic substance which is usually added to food as a preservative. This research was conducted to determine the levels of formalin in white tofu sold in traditional markets X. This research was conducted with a qualitative test using Schiff reagents and quantitative tests with Visible Spectrophotometry at a wavelength of 410 nm. The results of the study qualitatively showed that the samples tested positive contained formalin with a change in color to pink. The results of Visible Spectrophotometry readings for formalin standard solutions obtained linear regression y = 0.0537x + 0.0134 with a correlation coefficient (r2) of 0.9995. The results of formaldehyde in sample A were 23.41 mg / kg, sample B 26.57 mg / kg, sample C 58.02 mg / kg, sample D 41.71 mg / kg, and sample E were 90.35 mg / kg kg
Analisa Kepuasan Pasien Pulang Tentang Pelayanankonseling Obat Oleh Petugas Instalasi Farmasidi Rsup dr. Soeradji Tirtonegoro Klaten Rahmi Nurhaini; Muchson Arrosyid; Ima Rohmawati
CERATA Jurnal Ilmu Farmasi Vol 10 No 1 (2019): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v10i1.71

Abstract

The purpose of this study was to determine the level of patient satisfaction with medical counseling services by the Pharmacy Installation Officer dr. Soeradji Tirtonegoro Klaten. The research design is descriptive research. The sample used was 103 respondents, taken based on accidental sampling technique. The instrument for collecting data uses questionnaires. Data processing using descriptive analysis in the form of frequency, percentage, cross tabulation. The results of the study concluded that from 103 respondents: (1) 62 patients / families of patients were satisfied with the drug counseling service by the Pharmacy Installation officer dr. Soeradji Tirtonegoro Klaten; (2) 68 patients / families of patients are satisfied with the reliability of drug counseling services byofficer; (3) 51 patients / families of patients are satisfied with the responsiveness of drug counseling services by officer ; (4) 60 patients / families of patients are satisfied with the guarantee of drug counseling services by officer ; (5) 50 patients / families of patients were satisfied with the empathy of drug counseling services by officer ; (6) 56 patients / families of patients are satisfied with the tangible service of drug counseling officer .
Optimasi Formula Masker Gel Peel Off Ekstrak Buah Mahkota Dewa (Phaleria macrocarpa (Scheff.) Boerl ) Dengan Variasi PVA Dan HPMC Menggunakan Metode Simplex Lattice Design Nurul Hidayati; Nanik Widyiastuti; Sutaryono
CERATA Jurnal Ilmu Farmasi Vol 10 No 1 (2019): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v10i1.72

Abstract

Mahkota Dewa (Phaleria macrocarpa (Scheff.) Boerl) is an effectiveplant against bacteria the causes of acne. To facilitate the application, it formulated in a peel off gel mask preparation. This study aims to determine the effect of the concentration of PVA as film forming and HPMC as a gelling agent on the physical properties of the peel off gel mask and determine the concentration of PVA and HPMC which produce the optimum formula.The Mahkota Dewa fruit was extracted by soxletation with ethanol 70%. The extract was made into 5 runs with variations in the concentration of PVA (10-16%) and HPMC (2-4%). The fifth run in the test of physical properties include organoleptic tests, homogenity, pH, viscosity, spreadability, adhesion and drying time. The optimum formula of peel off gel mask is obtained from software design expert version 6.0.8. simplex lattice design method with the studied response to viscosity, spreadability, and drying time.The results show that increasing the concentration of PVA can increase viscosity and drying time, and increasing the concentration of HPMC can increase the value of dispersion of the preparation. The optimum formula was obtained with a variation of PVA 13.09% and HPMC of 2.97%.
Kesiapan Apoteker dalam Memberikan Layanan Medication Therapy Management Heni Lutfiyati; Prasojo Pribadi; Setiyo Budi Santoso
CERATA Jurnal Ilmu Farmasi Vol 10 No 1 (2019): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v10i1.74

Abstract

Optimizing the implementation of the referral program is one of BPJS 'top programs. BPJS Health implements a referral program based on Medication Therapy Management. Medication therapy management interventions can reduce the frequency of drug-related problems, including non-compliance, and reduce health care costs. The purpose of this study was to evaluate the readiness of pharmacists in providing medication therapy management services This research uses a descriptive method by using a questionnaire as an instrument for data retrieval. The sampling technique is convenience sampling. The population is pharmacists who practice pharmaceutical services and are willing to fill out questionnaires. The result most pharmacists feel they have enough clinical knowledge and experience to provide MTM services. There are still many pharmacist workplaces (Puskesmas, Pharmacies and hospitals) that have not yet prepared to provide MTM services. Pharmacists think they have a desire to provide MTM services and have sufficient access to information in designing appropriate MTM services and pharmacists should be involved in providing MTM services. The obstacles faced by pharmacists in providing MTM services are insufficient time, insufficient human resources, limited space, limited information regarding MTM services, and the costs needed to implement MTM. Pharmacists are willing to provide Medication Therapy Management services but many obstacles remain. Training is needed so that pharmacists become more confident in providing clinical services
Faktor-Faktor Yang Mempengaruhi Kepatuhan Pasien Dalam Mengkonsumsi Obat Antihipertensi Di Puskesmas Jatinom Sri Handayani; Rahmi Nurhaini; Tri Jannah Aprilia
CERATA Jurnal Ilmu Farmasi Vol 10 No 2 (2019): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v10i2.75

Abstract

Many degenerative diseases occur because of an unhealthy lifestyle. One type of degenerative disease is hypertension. Hypertension is a disease that requires long-term therapy, so it requires patient coverage in the treatment needed to control blood pressure and reduce the risk of complications. This study discusses the factors that influence the consideration of patients in taking antihypertensive drugs.This research is a descriptive analytic research with cross sectional design. The population of the study amounted to 1215 with an average of 101 hypertension visits a month. The number of samples taken was 50 respondents by accidental sampling. Measurement of compliance was carried out using the MMAS (Modified Morisky Adherence Scale) questionnaire.The results of this study can be concluded that the factors of sex, level of last education, employment status, duration of hypertension, insurance participation, level of knowledge, access to health services, family support, the role of health workers, and motivation for treatment, have no relationship with compliance in taking antihypertensive drug
Penetapan Kadar Air Dan Kadar Protein Pada Biskuit Yang Beredar Di Pasar Banjarbaru Normilawati; Fadlilaturrahmah; Samsul Hadi; Normaidah
CERATA Jurnal Ilmu Farmasi Vol 10 No 2 (2019): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v10i2.77

Abstract

Many biscuits circulating in the community are not labeled and do not include the value of water and protein content in accordance with SNI. Therefore, it is necessary to determine the water content and protein content in the biscuits. Determination of water content and protein content in biscuits was carried out on 2 biscuit samples taken at the Banjarbaru Market. The water content test on the sample was carried out by the gravimetric method and the protein content test was carried out by the Kjeldahl method. The results obtained were the test of water content of 2 biscuit samples respectively at 4.43% and 3.84%. While the results of the protein content test from 2 samples are 5.31% and 6.89%, respectively. According to SNI 01-2973-2011 the water content limit does not exceed 5% while the protein content limit is a minimum of 5%. The results of 2 samples showed the water content and protein content in accordance with SNI.
Aktivitas Antibakteri Ekstrak Etanol Daun Ketapang (Terminalia Catappa L) Terhadap Bakteri Streptococcus Mutans Asnan Nugroho; Sholikhah Deti Andasari
CERATA Jurnal Ilmu Farmasi Vol 10 No 2 (2019): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v10i2.78

Abstract

Ketapang leaf (Terminalia catappa L) was a plant that has many benefits, one of which was antibacterial because it has active compounds such as alkaloids, flavonoids and tannins. The aimed of this study was to determine the effectiveness of the ethanol extract of ketapang leaf (Terminalia catappa L) as an antibacterial against Streptococcus mutans. This study used an experimental method, ketapang leaves as much as 500 grams macerated with ethanol 96% solvent for 5 days resulted in a yield of 8.68%. The ethanol extract of leaves obtained was tested for antibacterial effectiveness against Streptococcus mutans bacteria with variations in concentrations of 25%, 50%, and 75% by diffusion method. Determination of the inhibition zone was done by measuring the diameter of the clear zone formed around the disc. The results showed that at concentrations of 25%, 50% and 75% respectively 4.48 mm, 7.88 mm and 9.70 mm. Whereas the inhibitory zones in negative and positive controls are 0 mm and 19.70 mm respectively. The results show that the greater the concentration of extract the greater the inhibition zone formed. So, ethanol extract of ketapang leaves effectively inhibits the growth of Streptococcus mutans.
Analisis Kandungan Asam Retinoat Pada Sediaan Krim Malam Yang Beredar Di Toko X Kota Klaten Dengan Spektrofotometri UV-Vis Yenni Kusuma Wardhani; Anita Agustina Styawan; Choril Hana Mustofa
CERATA Jurnal Ilmu Farmasi Vol 10 No 2 (2019): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v10i2.79

Abstract

Whitening cosmetics are cosmetics that contain an active whitening ingredient to brighten the skin. Retinoic acid is prohibited from being used in whitening creams because it can cause dry, burning, carcinogenic and teratogenic skin. The purpose of this study was to determine the levels of retinoic acid contained in night creams. The sample in this study were 5 night cream products circulating in Klaten City X Store. This study was conducted to determine the content of retinoic acid in night creams using thin layer chromatography (TLC). Five positive samples contained retinoic acid by giving dark green spots and the concentration was determined by UV-Vis spectrophotometry.The results of this study indicate that in 5 samples of night cream circulating in Store X in the City of Klaten all positive for retinoic acid, that is, the average for sample A was 0.021%; sample B 0.014%; sample C 0.016%; sample D 0.025% and sample E 0.023%.

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