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Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan
Published by Asosiasi Riset Ilmu Kesehatan Indonesia
ISSN : 3031013X     EISSN : 30310148     DOI : 10.61132
Core Subject : Health,
Health Professions Nursing Public Health
Organisasi Farmasi, Kedokteran, Kimia Organik Sintetis, Kimia Alam, Biokimia, Analisis Kimia, Kimia Fisika, Biologi, Mikrobiologi, Jaringan Budaya, Botani dan Hewan terkait Produk Farmasi, Keperawatan, Kebidanan, Analis Kesehatan, Gizi dan Kesehatan Masyarakat.
Arjuna Subject : Profesi Kesehatan - Farmasi
Articles 339 Documents
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Hubungan Tingkat Kecemasan Ibu Hamil Dengan Kesiapan Menghadapi Persalinan Di Puskesmas Dolatrayat Kabupaten Karo Provinsi Sumatera Utara Tahun 2022 Pretti Ginting; Eka Purnamasari; Srilina Br Pinem; Heny Rista
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 3 (2024): May : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i3.356

Abstract

Anxiety in pregnant women is felt since the first trimester, where anxiety is a result of adapting to physical changes in the body, the uterus starting to enlarge, and changes in the breasts as well as psychological changes. This anxiety continues in the next trimester until the third trimester so it is thought to cause less preparation for childbirth later. The aim of the research was to determine the relationship between pregnant women's anxiety levels and readiness for childbirth at the Dolarayat Health Center, Karo Regency, North Sumatra Province. The type of research is analytical with a cross sectional approach. The population is 62 husbands and a sample of 56 people determined based on criteria. Data collection through distributing questionnaires. Data were analyzed univariately and bivariately. The results of the study showed that the anxiety level of third trimester pregnant women was more moderate (73.2%), and the anxiety level was mild (12%), while the anxiety level was severe (14.2%). More prepared for childbirth (76.8%) and less prepared (23.2%). There is a relationship between the level of anxiety of pregnant women and preparation for childbirth (p 0.004 <0.05). It is hoped that health workers can provide education and motivation to husbands, especially pregnant women, about how to deal with anxiety during pregnancy to avoid disorders during pregnancy and childbirth.
Pengaruh Senam Hamil Terhadap Penurunan Nyeri Punggung Bawah Pada Ibu Hamil Trimester II Di Puskesmas Sonomartani Kec. Kualuh Hulu Kab. Labuhanbatu Utara Tahun 2022 Meydriana Theodora; Eka Purnama; Siska Suci Triana Ginting; Ester Simanullang
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 3 (2024): May : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i3.357

Abstract

Pregnancy is a continuous chain and starts from ovulation, release of ovum, migration of spermatozoa and ovum, conception process, nidation (implantation) of the endometrium, formation of the placenta and growth and development of the products of conception for approximately 280 days (40 weeks) and no more of 300 days (43 weeks). The length of pregnancy from ovulation to parturition is approximately 280 days (40 weeks) (Rukiah & Yulianti, 2014). The aim of this study was to determine the effect of pregnancy exercise on reducing lower back pain in second trimester pregnant women at the Sonomartani District Health Center. Kualuh Hulu District. North Labuhanbatu in 2022”. Experimental type of research. Experimental research is a research design used to look for causal relationships with the involvement of research in manipulating independent variables (Nursalam, 2019). The sample in this study were all second and third trimester pregnant women at the Sonomartani District Health Center. Kualuh Hulu District. North Labuhanbatu in 2022 there will be 35 people. . The data collected in the research is primary data, namely data obtained directly from respondents. The data analysis used is chi square. The results of the tabulation research show a relationship between the duration of using injectable contraceptives for 3 months and menstrual disorders in 3-month injectable contraceptive acceptors at the Melak District Health Center. West Kutai, East Kalimantan in 2023 with a p-value = 0.049. So Ho is rejected and Ha is accepted, which means there is a relationship between the length of use of 3-month injectable contraceptives and menstrual disorders in 3-month injectable contraceptive acceptors at the Melak District Health Center. West Kutai, East Kalimantan in 2023. Conclusion: Family planning acceptors can choose the right contraceptive method. Family planning acceptors can tell midwives or health workers about the various types of contraceptives before choosing the contraceptive method. Always monitor changes in side effects so that if there are complaints they can be addressed immediately.
Hubungan Inisiasi Menyusui Dini (IMD) Dengan Pemberian Asi Eksklusif Di Puskesmas Sonomartani Kecamatan Kualuh Hulu Kabupaten Labuhan Batu Utara Tahun 2022 Pratiwi Puji Lestari; Srilina Br Pinem; Febriana Sari; Lisa Putri Utami Damanik
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 3 (2024): May : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i3.358

Abstract

Early Breastfeeding Initiation is the process of allowing the baby to breastfeed on its own immediately after birth. This is nature and a gift from God that has been arranged for us. Doing it is also not difficult, it only takes about one to two hours. IMD must be carried out immediately at birth, without delaying weighing or measuring the baby. Babies should also not be cleaned, only dried except for their hands. This process must take place skin to skin between baby and mother. This research uses an analytical type of research with a retrospective research design. The research aims to determine the relationship between early initiation of breastfeeding (IMD) and exclusive breastfeeding at the Sonomartani Community Health Center. Based on the data in table 4.3, it can be seen that 5 respondents (38.5%) did not practice IMD but did not provide exclusive breastfeeding and 8 respondents (61.5%) did not practice IMD but did not provide exclusive breastfeeding. Carrying out IMD and providing exclusive breastfeeding was 21 respondents (95.5%). The statistical test results of the chi square test obtained a p value = 0.000, so it can be concluded that there is a significant relationship between Early Breastfeeding Initiation (IMD) and exclusive breastfeeding, namely Ha received. The importance of giving birth in a health service is to avoid sudden emergencies that can cause complications and to provide care according to procedures. This is in line with research by Norhana, Arifin and Yulidasari (2016) that mothers who give birth in health facilities are 15,167 times more likely to carry out IMD. Of the 20 respondents who successfully carried out IMD, 19 respondents (95%) were accompanied by their husbands and family when giving birth and 17 respondents (84%) of them succeeded in providing exclusive breastfeeding. Husband and family support play an important role in managing IMD and building maternal self-confidence. The relationship between early initiation of breastfeeding (IMD) and exclusive breastfeeding at the Sonomartani Community Health Center in 2022" with a total of 35 respondents and data processing that has been carried out using SPSS, it can be concluded that the chi square test value is p < 0.05, meaning that Ho is rejected and Ha is accepted: Based on the research results, the majority of respondents who carried out Early Breastfeeding Initiation (IMD) were 22 respondents (62.9%). Based on the research results, the majority who gave exclusive breastfeeding were 26 respondents (74.3%). Based on the research results, there is a relationship between carrying out IMD and providing exclusive breastfeeding. The statistical test results obtained a chi square test value (p < 0.05) with a value of 0.000.
Analisis Implementasi Tujuh Langkah Menuju Keselamatan Pasien di Ruang Rawat Inap Rumah Sakit Nisrina Nisrina
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 1 No. 6 (2023): November : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v1i6.360

Abstract

Patient safety is an absolute thing in the service of a hospital. Services that promote a sense of security and comfort are the hopes of every patient when receiving health services. However, the high number of unexpected events in health services at hospitals become an indication that the implementation of patient safety management, especially the seven steps towards patient safety, is not running well. The research method in this study was descriptive qualitative. The data collection techniques used were interviews, observation, and documentation study. From this study, it was found that the implementation of patient safety management on the seven steps towards patient safety has been carried out in hospitals, but there are still obstacles that resulted in the implementation that is not being maximized. Improvement efforts should be continued to implement the seven steps program towards patient safety optimally.
Uji Efektivitas Antiinflamasi Sediaan Krim Kombinasi Ekstrak Rimpang Kencur (Kaempferia galanga L.) Dan Daun Srikaya (Annona squamosa L.) Pada Tikus Yang Diinduksi Karagenin Akmal Aziz; Galih Samodra; Sunarti Sunarti
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 3 (2024): May : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i3.361

Abstract

Inflammation is the body's response when it experiences injury, infection, antigen or cell damage, so it is a sign of something that is harmful to the body or disease. Galangal rhizomes (Kaempferia galanga L.) and Srikaya leaves (Annona squamosa L.) are plants that contain flavonoid compounds which have anti-inflammatory potential by inhibiting the enzymes cyclooxygenase and lipooxygenase. The aim of this research was to determine the effectiveness of a combination cream preparation of galangal rhizome extract and srikaya leaf extract as an anti-inflammatory. The various combinations used are a combination of 15 grams of kecur rhizome extract and 10 grams of srikaya leaf extract, 12.5 grams of srikaya rhizome extract and 12.5 grams of srikaya leaf extract, 10 grams of srikaya rhizome extract and 15 grams of srikaya leaf extract. The anti-inflammatory test uses 1% carrageenin induction of 0.1 ml, then the swelling that occurs is measured using a plastinometer. Based on the results obtained, a good anti-inflammatory power value was a combination of 15 grams of kencur rhizome extract with 10 grams of srikaya leaf extract with a value of 21.6216%. The results of the One Way Annova analysis obtained a p-value >0.05, which means there is no significant difference. So it can be concluded that various combinations of galangal rhizome extract and srikaya leaves are effective in mice induced by carrageenin. A post hoc Tuckey test was carried out on the AUC value, obtaining a p-value >0.05, so it can be concluded that there was no significant difference in the positive controls for formulas 1, 2 and 3.
Uji Intensitas Warna Kuning pada Campuran Sari Kunyit-Daun Salam dan Temulawak Daun Salam Sebangai Pewarna Pangan Putri Intan Sari; Anny Sartika Daulay; Ridwanto Ridwanto; Haris Munandar Nasution
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 3 (2024): May : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i3.363

Abstract

Some food industries still use synthetic dyes. Synthetic dyes, if consumed, can harm your health. Turmeric can be used as a natural food coloring. This natural coloring is applied to sweet jelly. This natural coloring agent must be used in fresh juice. To extend the use time of the natural dyes turmeric-bay leaves, ginger-bay leaves, this research was carried out in a variety of storage conditions without using preservatives. The aim of the research was to determine the results of the content of secondary metabolite compounds in turmeric-laurel extract, curcuma-laurel extract, turmeric extract and curcuma extract, in making solid preparations using preservatives, namely citric acid, maltodextin and sucrose. This research uses experimental methods with Sari method is done on a mixture of turmeric-bay leaves and ginger-bay leaves using a water solvent using the distillation method. Determination of variations in storage conditions was carried out for 7 days and the effect of storage temperature. Color stability and intensity measurements were carried out using visible spectrophotometry and characterization methods. The results of this research were obtained. The absorbance intensity test on turmeric-bay leaves was carried out at a wavelength of 425.14 nm with a result of 0.442 (day 1), ginger-bay leaves had an absorbance of 0.490 ( day 1). In the color stability test, there was a change in color from day 3 at drying cupboard temperature, at refrigerator temperature and at room temperature, the color remained stable.
Efektivitas Sabun Cuci Tangan Ekstrak Daun Afrika ( Vernonia amygdalina Del.) Terhadap Bakteri Escherichia coli Panji Ratih Suci; Cikra Ikhda Nur H.S; Anita Candra Ningtyas; Annisa Lailatul Maghfiroh
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 3 (2024): May : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i3.364

Abstract

African leaf plants (Vernonia amygdalina Del.) is one of tradisional medicine and has pharmacological contain secondary metabolite such as Flavonoids, Saponin, Tanin and Alkaloid. This study aimed to determine the antibacterial activity of African leaf extract (Vernonia amygdalina Del.) in handsoap formulation on the growth of Escherichia coli. African left extract was obtained from maceration process with ethanol and phytochrmical screening was carried out.This study uses concentration of 0,5%, 1% and 2%. Antibacterial activity testing using scratch and disc diffusion methods. Tis study also evaluated the pyshical quality of the preparation which included organoleptic observation, homogeneity test, high foam test and antibacterial activity test. Antibacterial activity testing using scratch and disc disfusion methods. African pyctochemical screening was carried out. The result showed that the percentage of African leaf extract yield was 24,958%. The pH test gets a pH of 10-11 and 5-6 cm foam height test. The highest concentration of positive control of preparation containing alcohol (Dettol) with an average number og 4,72 mm ± 1,45 mm. Liquid soap preparation 1% with a diameter of inhibition of 3,93 mm ± 1,97 mm. The result of this study inhibit the growth of Eshcherichia coli bacteria.
Daya Hambat Staphylococcus Aureus Terhadap Ekstrak Metanol Daun Sirsak (Annona Muricata L.) Amjad Mohammad Nadlif; Muhammad walid
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 3 (2024): May : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i3.365

Abstract

The use of antibiotics can cause drug resistance if their use is not appropriate, so alternative treatment from plants is needed, one of which is soursop leaves (Annona muricata L.). Chemical substances contained in soursop leaves can prevent development until they can kill bacteria, one of which is flavonoids. The purpose of this study was to determine whether soursop leaf methanol extract (Annona muricata L.) at concentrations of 25%, 50%, 75% can inhibit the growth of Staphylococcus aureus bacteria and can determine at what concentration soursop leaf extract (Annona muricata L.) can effectively inhibit Staphylococcus aureus. The simplisia extract was done by maceration strategy using methanol as a solvent. The antibacterial testing method uses the disc diffusion method and uses clindamycin as a positive control and distilled water as a negative control. The results showed that Annona muricata L. extract can provide antibacterial action at concentration variants of 25%, 50% and 75% which is characterized by the presence of transparent areas with an average diameter of 8.97mm, 11.36 mm and 13.3mm respectively with positive control with a diameter of 23.25 and negative control with a diameter of 0 mm. Soursop leaf methanol extract (Annona muricata L.) is able to suppress the growth of Staphylococcus aureus bacteria with the most effective concentration variant of 75%.
Daya Hambat Bakteri Staphylococus Aureus Pada Ekstrak Metanol Daun Jambu Biji Merah (Psidium Guajava L. Var. Pomifera) Muhammad Irfan Zidni; Muhammad Walid
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 3 (2024): May : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i3.366

Abstract

Staphylococcus aureus infection is one of the causes of increasing number of diseases and deaths. It is estimated that currently around 2-3% of the general population has MRSA in their bodies. People with MRSA on their bodies are estimated to have a 64% higher chance of dying. The purpose of this study was to determine the antibacterial activity of red guava leaves against Staphylocoocus aureus bacteria and to determine the amount of inhibition of methanol extract from red guava leaves against the activity of Staphylocoocus aureus bacteria. This type of research is experimental research The object of this study is the inhibitory power of Staphylococcus aureus bacteria in methanol extract of red guava leaves. The sample used in this study was methanol extract of red guava leaves. This research was conducted using maceration extraction method with the solvent used is methanol. The measurement results showed that red guava leaf methanol extract at concentrations of 25%, 50%, 75% and 100% had an inhibitory zone on the antibacterial activity of Staphylococus aureus. The greatest bland result at a concentration of 50% of 0.49 mm. The lowest inhibitory power is at a concentration of 75% of 0.26 mm.
Studi Literatur: Penetapan Kadar Bahan Kimia Obat Natrium Diklofenak Pada Sediaan Jamu Menggunakan Metode Kromatografi Lapis Tipis Dan Spektrofotometri UV-Vis Jacinda Caroline Nathania; Siska Rusmalina
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 3 (2024): May : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i3.369

Abstract

Herbal medicine is a traditional medicine that is in great demand because it is made from natural ingredients with minimal side effects. This creates irresponsible producers who add BKO to increase sales. One of the medicinal chemicals that is often added is diclofenac sodium. The aim of this research is to review the journal of medicinal chemical analysis (BKO) of sodium diclofenac in herbal medicine in order to determine the effectiveness of the stationary phase and mobile phase in the thin layer chromatography method and the effectiveness of the solvent in UV-Vis spectrophotometry in the analysis of the medicinal chemical of sodium diclofenac in preparations herbal medicine. This research method is a literature study, by searching for articles on the Google Scholar database. Some of the keywords used include solvent optimization in the analysis of diclofenac sodium in herbal medicine preparations using the TLC method and UV-Vis spectrophotometry, optimization and validation of determining the levels of diclofenac sodium in herbal medicine preparations using the TLC method and UV-Vis spectrophotometry, analysis of diclofenac sodium in herbal medicine preparations. using the TLC method and UV-Vis spectrophotometry, and validation of determining the levels of diclofenac sodium in herbal preparations using the TLC method and UV-Vis spectrophotometry. The search strategy is limited by using several filters, including publication year between 2018 – 2023, selection of full text type and English and Indonesian. This research method is a literature study, by searching for articles on the Google Scholar database. Some of the keywords used include solvent optimization in the analysis of diclofenac sodium in herbal medicine preparations using the TLC method and UV-Vis spectrophotometry, optimization and validation of determining the levels of diclofenac sodium in herbal medicine preparations using the TLC method and UV-Vis spectrophotometry, analysis of diclofenac sodium in herbal medicine preparations. using the TLC method and UV-Vis spectrophotometry, and validation of determining the levels of diclofenac sodium in herbal preparations using the TLC method and UV-Vis spectrophotometry. The search strategy is limited by using several filters, including publication year between 2018 – 2023, selection of full text type and English and Indonesian.

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