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INDONESIA
Ophthalmologica Indonesiana
ISSN : 01261193     EISSN : 2460545X     DOI : 10.35749
Core Subject : Health,
Ophthalmologica Indonesiana is an open accessed online journal and comprehensive peer-reviewed ophthalmologist journal published by the Indonesian Ophthalmologist Association / Perhimpunan Dokter Spesialis Mata (PERDAMI). Our main mission is to encourage the important science in the clinical area of the ophthalmology field. We welcome authors for original articles (research), review articles, interesting case reports, special articles, clinical practices, and medical illustrations that focus on the clinical area of ophthalmology medicine.
Articles 869 Documents
Successful Rate of Glaucoma Surgery in Secondary Glaucoma after Vitrectomy in Kariadi General Hospital Semarang 2020-2022: Oral Presentation - Observational Study - Resident Ismail, Nur Azizah Intan Putri; Maharani; Rahmi, Fifin L.; Puspasari, Denti
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/01mhar90

Abstract

Introduction & ObjectivesGlaucoma is one of the most frequent complications of vitrectomy surgery. It can cause a significantrise in intraocular pressure (IOP). Glaucoma surgery can be planned in medically uncontrolledglaucoma. Trabeculectomy and Glaucoma Drainage Device (GDD) implantation are the mostfrequent filtering surgeries used in these cases. This study aims to define the success rate ofglaucoma surgery in secondary glaucoma after vitrectomy. MethodsThis study is an analytical observational study with retrospective data collection held from medicalrecords of patients with secondary glaucoma after vitrectomy who underwent glaucoma surgery inKariadi General Hospital Semarang from 2020-2022. Surgical success defined by postoperative IOPreduced by>20% from baseline, with or without anti-glaucoma medication. ResultsThere were 16 eyes of trabeculectomy with 5-fluorouracil (5-FU), and 8 eyes of GDD implants. Themean preoperative IOP was 43.76+6.77 mmhg for trabeculectomy 5-FU, and 42.43+4.02 mmhg forGDD implant. IOP levels in both groups varied significantly after one day, one week, one month, andthree months after surgery (p<0.05). The success rate for the trabeculectomy 5-FU group was81.25% and the GDD implant group was 87.5% in 3 months. There was no statistically significantdifference in the success rate between the trabeculectomy 5-FU and GDD implant groups (p=0.839).The complication for the GDD implant group was 25%. No complications were found in thetrabeculectomy 5-FU group. ConclusionThere was no significant difference in the success rate between trabeculectomy 5-FU and the GDDimplant group. Both groups are viable for glaucoma surgery in secondary glaucoma after vitrectomysurgery.
Trabeculectomy Versus Tube Outcome in Neovascular Glaucoma: Oral Presentation - Observational Study - Resident Syahiqoh, Daisy Syakhsiatusy; Rahmi, Fifin Luthfia; Puspasari, Denti; Maharani
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/73qxtp82

Abstract

Introduction & ObjectivesNeovascular glaucoma (NVG) is known to be a refractory form of glaucoma, which frequentlyrequires the integrated use of medical, laser and incisional surgery. Tube-shunt implantation andtrabeculectomy with antifibrotic agent are the two most-popular incisional procedures for managingrefractory glaucoma. This study aims to compare surgical outcome between patients who underwenttrabeculectomy versus tube-shunt implantation for the treatment of NVG. MethodsA retrospective study was held of NVG patients that underwent trabeculectomy and tube-shuntimplantation between January 2020 - December 2022 at Dr. Kariadi Hospital, Semarang. IOPoutcome and success rate was measured at 3 months post operatively. Statistical analysis was usedto compare the outcome between groups, p<0.05 was considered significant. ResultsThere were no significant differences in characteristics between groups at baseline. Mean IOPmeasured at 3 months post operatively was 18.58 ± 5.53 and 15.94 ± 10.79 in trabeculectomy andtube group respectively (p=0.04), complete success rate was 18.8% in trabeculectomy and 25% intube group, qualified success rate was 37.5% in trabeculectomy and 56.3% in tube group. Greaterfailure rate was observed in trabeculectomy group (43.8%). ConclusionCompared to trabeculectomy, tube-shunt implantation has lower IOP at 3 months post operatively inNVG. Greater failure rate was observed in trabeculectomy.
COMPARISON OF SITA STANDARD 24-2 WITH SITA FASTER 24-2C PROGRAM ON HUMPHREY FIELD ANALYZER IN ASSESSING VISUAL FIELD DEFECTS OF GLAUCOMA PATIENTS: Oral Presentation - Observational Study - Resident Rianti, Nuzul; Satari, Karmelita; Gustianty, Elsa; Prahasta, Andika; Rifada, R. Maula; Umbara, Sonie
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/5a6xfs73

Abstract

Introduction & ObjectivesIntroduction: Periodical perimetry examination to detect and determine the rate of glaucomaprogression continues to be a challenging task, because it depends on many factors. Besides, thereis now a paradigm shift which central visual field defects occur earlier. SITA Standard (SS) 24-2 isthe clinical standard for glaucoma examination, but there were studies reporting on the prevalenceof central visual field defects not detected. SITA Faster (SFR) 24-2C was developed to addresscurrent shortcomings, but the performance has yet to be formally and independently assessed.Objectives: To compare the global indices (Mean Deviation, Pattern Standard Deviation, Visual FieldIndex) and test duration between SS 24-2 and SFR 24-2C program. MethodsThis is an analytical observational study with a cross-sectional design. Subjects aged >18 years whodiagnosed with glaucoma and whose visual fields unaffected by other condition besides glaucomawere included. All subjects underwent testing of both programs. ResultsThis study was conducted in 94 eyes of 66 patients. Comparison of global indices and test durationbetween the two programs was carried out by the Wilcoxon test. The mean results of MD and PSDglobal indices were not significantly different, however there was a difference in the mean VFI of1.5% between the two programs. The test duration of SFR 24-2C was 55.03% faster. ConclusionThere was no significant difference in the MD and PSD global indices, but there was a significantdifference in the VFI, as well as the test duration between the two programs.
Success Rate of Glaucoma Drainage Device Implantation in Kariadi General Hospital Semarang 2020-2022: Oral Presentation - Observational Study - Resident Apriliana, Rina; Rachmi, Fifin L; Puspasari, Denti; Maharani
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/270xg831

Abstract

Introduction & ObjectivesGlaucoma is a leading cause of irreversible blindness, and implantation of drainage devices is aneffective treatment option for patients with advanced glaucoma. The purpose of this study was toinvestigate success rate of glaucoma drainage devices implantation in Kariadi Hospital MethodsThis study was an observational analytic study with a retrospective design. All patients who receivedVirna implantation between January 2020 and December 2022 were included. Intraocular pressure(IOP) examination was performed at baseline and at the first day, seventh day, first month, and thirdmonth following surgery. The success rate was divided into three groups: complete success if IOPwas <21mmHg without medication, qualified success if IOP was <21mmHg with medication, andfailure if IOP was >21mmHg with medication. ResultsThis study included 42 patients (42 eyes) with an average age of 43.3 years. There were 16 male(38%) and 26 female (62%) patients in the group. Of these patients, 11 (26.2%) had primaryglaucoma and 31 (73.8%) had secondary glaucoma. There was significant decrease in IOP frompreoperative measurement (37.1±10.1mmHg) compared to IOP on first day (13.0±6.0mmHg),seventh day (15.4±3.8mmHg), first month (18.2±4.4mmHg), and third month (23.4±8.9mmHg) aftersurgery (p<0.05). At three-month follow-up, complete success was 14.29%, qualified success was50%, and failure was 35.71%. ConclusionGlaucoma drainage device implantation was found to successfully reduce IOP in patients withadvanced glaucoma. The qualified success rate was higher than complete success rate, suggestingthat some patients may require medication to achieve target IOP levels.
RELATIONSHIP BETWEEN DEGREE OF OPTICAL NERVE DAMAGE ON LEVEL OF DEPRESSION AND ANXIETY PATIENT WITH PRIMARY GLAUCOMA: Oral Presentation - Observational Study - Resident SETIAWAN, I KADEK AGUS; Rahayu, Ni Kompyang; Ariani, Ni Ketut Putri; Widiana, I Gde Raka; Kusumadjaja, I Made Agus; Juliari, I Gusti Ayu Made
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/qeatyj71

Abstract

Introduction & ObjectivesGlaucoma is one of the leading causes of irreversible global blindness and the second most commoncause of blindness in the world after cataracts. Depression and anxiety often occur in glaucomapatients when glaucoma is first diagnosed, the effect of decreased vision function in glaucoma, sideeffects of glaucoma therapy both medically and surgically and financial effects due to length oftreatment and loss of job due to limited vision. This study aims to determine the relationship of thedegree of optic nerve damage to the level of depression and anxiety in patients with primaryglaucoma. MethodsThis research is an analytic, prospective observational research with a cross-sectional studyapproach. The relationship between independent variables and dependent variables was analyzed. ResultsThe Man Whitney test found a significant difference in anxiety scores between the severe and mildto moderate groups with a p value of 0.020 . The ANCOVA test found that there was a relationshipbetween the degree of optic nerve damage in primary glaucoma and the level of anxiety aftercontrolling for control variables. ConclusionThis study can be concluded that there is a difference in the level of anxiety between the degree ofsevere and mild to moderate optic nerve damage. The level of anxiety itself corresponds to thedegree of damage to the optic nerve. The more severe the damage to the optic nerve, increased ofthe patient's anxiety score.
Comparison Between Results of Trabeculectomy With or Without Anti- Vascular Endothelilal Growth Factor in Patients With Neovascular Glaucoma at Undaan Eye Hospital Surabaya, Indonesia: Oral Presentation - Observational Study - General Practitioner Malika, Rosalia Adriani; Nuradianti , Lydia
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/gj027w51

Abstract

Introduction & ObjectivesNew intraocular medication, Anti-vascular endothelial growth factor (Anti-VEGF) agents has beendeveloped in the management of neovascular glaucoma and in glaucoma surgery. But there are nostudies comparing trabeculectomy with Anti-VEGF to no Anti-VEGF treatment in patients withneovascular glaucoma. This study aims to compare decrease of intraocular pressure (IOP) betweentrabeculectomy with Anti-VEGF and without Anti-VEGF in neovascular glaucoma. MethodsThis observational retrospective study comprised 30 medical records of neovascular glaucoma,divided to 15 medical records of patients with anti-VEGF before trabeculectomy and medical recordsof patients operated with trabeculectomy without anti-VEGF, monitored between January 2021 toDecember 2021. Patients with incomplete medical records were excluded. Data collected are age,gender, risk factor, intraocular pressure pre operative, and during 6 months follow-up IOP postoperative. Data analysis uses an Independent T test. ResultsFrom 30 samples, mean IOP in trabeculectomy with anti-VEGF group generally is 12,26 mmHg.Meanwhile, mean IOP in trabeculectomy without anti-VEGF group generally is 16,74 mmHg. Tindependent test between 2 groups shows that there are significant mean difference between themduring 1-5 months follow-up (1 month: p = 0,022; 2 months: p = 0,007; 3 months: p = 0,007; 4months: p = 0,042; 5 months: p = 0,029). ConclusionTrabeculectomy with prior administration of intravitreal anti-VEGF shows good IOP reduction andcan be implemented in NVG patients.
ASSOCIATION BETWEEN ESTROGEN LEVELS WITH INTRAOCULAR PRESSURE IN PRIMARY OPEN ANGLE GLAUCOMA PATIENT: Oral Presentation - Observational Study - Resident Rambe, Alvin; Sari, Masitha Dewi; Aldy, Fithria; Ashar, Taufik
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/697gtq43

Abstract

Introduction & ObjectivesThere are studies that state that estrogen deficiency can exacerbate visual disturbances in glaucomapatients. To determine the relationship between estrogen levels and intraocular pressure (IOP) inpatients with POAG. MethodsThis study used a case-control design in 30 POAG patients who came to the OphthalmologyPolyclinic at the University of North Sumatra Hospital and Network Hospital. The data collectionmethod in this study used a consecutive sampling technique starting from February 2022 until thesample was filled. The inclusion criteria in this study were all women with POAG who were ?40years old and willing to be the research sample. The exclusion criteria for this study were patientswith a history of secondary glaucoma or a history of optic nerve disease, a history of ocular surgery(except cataracts), a history of orbital trauma, menstrual disorders, or currently on hormonaltherapy, a history of systemic or autoimmune disease. Data is then collected and analyzed. ResultsOf the 30 patients with POAG, the majority were aged 45-65 years (46.7%) with an average age of55.87(±12.91) years and had suffered from POAG for an average of 1.62(±2.08) years. The averagepatient had an intraocular pressure of 25.07(±6.12) mmHg, MD -12.99(±8.28) dB, VCDR0.78(±0.13) mm, and estrogen levels 2.47(±2.11) pg/dL. There was no significant relationshipbetween estrogen levels and intraocular pressure (p=0.851). ConclusionThere was no significant association between estrogen levels and intraocular pressure in patientswith POAG.
COMPARISON OF ANGLE OPENING DISTANCE AND TRABECULAR IRIS SPACE AREA BEFORE AND AFTER LASER PERIPHERAL IRIDOTOMY IN ANGLE CLOSURE DISEASE: Oral Presentation - Observational Study - Resident Ramdhani, Rizki Fasa; Rifada, R. Maula; Irfani, Irawati; Gustianty, Elsa; Umbara, Sonie
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/05vxs382

Abstract

Introduction & ObjectivesLaser peripheral iridotomy (LPI) is the standard first-line therapy in angle closure disease toincrease anterior chamber angle width. Spectral Domain Anterior Segment Optical CoherenceTomography (SD AS-OCT) is an instrument that has a quantitative parameter to measure anteriorchamber angle. Angle opening distance (AOD) and trabecular iris space area (TISA) are quantitativeparameters in SD AS-OCT. The purpose of this study is to compare AOD and TISA before and oneweek after LPI in angle closure disease. MethodsThis is an analytical prospective study with a cross-sectional study design. Twenty-two eyes withangle closure disease that met inclusion and exclusion criteria underwent LPI and SD AS-OCT beforeand one week after LPI. Analysis was performed using SD AS-OCT parameters, such as AOD(AOD500, AOD750) and TISA (TISA500, TISA750) in the temporal, nasal quadrants, and average. ResultsTwenty-two eyes with angle closure are divided into nine eyes with primary angle closure suspect,seven eyes with primary angle closure, and six eyes with primary angle closure glaucoma. The meanage of participants was 57.86±7.63 years. There was a significant increase in AOD500, AOD750,TISA500, and TISA750 in the temporal and nasal quadrants, as well as in the average (P=0.0001)based on a paired t test or Wilcoxon as an alternative. Average AOD750 had the highest T-value (T=6.329) with a mean 0.20±0.096 before LPI and 0.31±0.144 one week after LPI. ConclusionThere was a significant increase in AOD and TISA after one week LPI in angle closure disease.
REDUCTION OF INTRAOCULAR PRESSURE POST MICRO PULSE TRANSSCLERAL CYCLOPHOTOCOAGULATION IN REFRACTORY GLAUCOMA PATIENTS: Oral Presentation - Observational Study - Resident Rahayu, Annisa; Gustianty, Elsa; Knoch, Andrew M.H; Rifada, Maula; Umbara, Sonie
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/tyq5vs98

Abstract

Introduction & ObjectivesCyclodestructive laser is one of the last resource managements for refractory glaucoma, especiallywith low visual potential. Conventional laser using CW-TSCPC showed unstable IOP reduction withcollateral tissue damage. MP-TSCPC using on and off cyclic waves is considered to have a gooddegree of IOP reduction and fewer complications. The purpose of this study is to assess the IOPreduction after the MP-TSCPC procedures for patients with refractory glaucoma. MethodsThis is a prospective observational study for refractory glaucoma patients treated with the MPTSCPClaser procedure. Measurement of IOP was carried out preoperatively and on postoperativedays 1, 7, and 30 with the gold standard Goldmann applanation tonometry. ResultsA total of 33 eyes from 33 patients were enrolled in this study. The mean baseline IOP was 48.45 ±12,79 mmHg. The mean degree of IOP reduction on follow-up days 1, 7, and 30 were 14.39 ±23.52%, 45,83 ± 24,80 and 27.09 ± 23.86% respectively. On the 30th day after the laser treatment,no complications were observed. The number of anti-glaucoma medication was reduced from 2.39 ±0.49 at the baseline to 1.91 ± 0.58 at one month follow up. ConclusionMicro-pulse transscleral cyclophotocoagulation laser showed a good degree of IOP reduction with noincidence of complication observed at day 30.
The Role of Tumor Necrosis Factor (TNF) Alpha with Visual Field Defects in Primary Open Angle Glaucoma (POAG): Oral Presentation - Observational Study - Resident Hutabarat, Muhammad Hendy Hasudungan; Sari, Masitha Dewi
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/19xr0h91

Abstract

Introduction & ObjectivesGlaucoma is a group of progressive optic neuropathy disease characterized by degeneration ofretinal ganglion cells. This causes changes in the optic nerve and loss of visual field. Several studieshave revealed that there is a role for TNF Alpha in glaucoma cases. To determine the role TumorNecrosis Factor (TNF) Alpha Levels between visual field defects in Primary Open-angle Glaucomapatients. MethodsThis study is Observational Analytical with cross sectional data collection method. Examination ofthe field of view using the Humphrey visual field perimetry. ResultsThe sample of this research was 30 people with 16 (53.3%) male and 14 people (46.7%) female.Using the Spearman correlation test, it showed that there was no significant correlation betweenTNF alpha and field of view (p = 0.119). ConclusionTNF Alpha level was not significantly related to visual field defects.