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Ophthalmologica Indonesiana
Published by Perhimpunan Dokter Spesialis Mata Indonesia
ISSN : 01261193     EISSN : 2460545X     DOI : 10.35749
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
Ophthalmologica Indonesiana is an open accessed online journal and comprehensive peer-reviewed ophthalmologist journal published by the Indonesian Ophthalmologist Association / Perhimpunan Dokter Spesialis Mata (PERDAMI). Our main mission is to encourage the important science in the clinical area of the ophthalmology field. We welcome authors for original articles (research), review articles, interesting case reports, special articles, clinical practices, and medical illustrations that focus on the clinical area of ophthalmology medicine.
Arjuna Subject : Kedokteran - Ophthalmology
Articles 869 Documents
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Microinvasive Glaucoma Surgery using Goniotomy as A Potential Surgical Treatment Modality in Indonesia: A Descriptive Study and Literature Review: Oral Presentation - Observational Study - Resident Wetarini, Krisnhaliani; Rahayu, Ni Kompyang; Kusumadjaja, I Made Agus; Suryaningrum, I Gusti Ayu Ratna
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/2y3b6478

Abstract

Introduction & ObjectivesMicro-invasive glaucoma surgery with goniotomy is a recent surgical treatment modality that targetsthe trabecular outflow to maintain intraocular pressure. This study aims to describe the clinicaloutcomes of excisional goniotomy using KDB and to review the published literature regarding amodified goniotomy technique as a potential surgical treatment modality in Indonesia. MethodsA cross-sectional descriptive study was conducted in patients that underwent goniotomy stand-aloneor combined with cataract surgery. Main outcome parameters consist of visual acuity, intraocularpressure (IOP), number of glaucoma medications, and complications during post-operative follow-up. ResultsA total of 7 patients (8 eyes) were included in the study, consisting of 5 (71,4%) males and 2 (28,6%)females. The mean age of the subjects was 47.7 years. Subjects consisted of primary,pseudoexfoliative, steroid-induced, and angle-recess glaucoma. Mean pre-operative IOPmeasurements showed 20.74 mmHg with visual acuity consisting of 1 (14.3%) mild visualimpairment and 7 (85.7%) severe visual impairment. Postoperatively there was progressiveimprovement in the mean IOP to 13.81 and 11.31 mmHg on first-day and one-week follow-up,respectively. Visual improvement was observed in 2 (28.5%) with mild visual impairment, 3 (42.6%)with severe visual impairment, and 2 (28.5%) with hand movement due to complications of cornealedema following phacoemulsification. A week later, visual acuity improved to 4 (57.1%) with mildvisual impairment and 3 (42.9%) with moderate visual impairment. ConclusionGoniotomy is a simple surgical method that may be applied in Indonesia as a novel technique toprovide an effective intraocular pressure-lowering effect.
Surgery Outcomes of Glaucoma Drainage Device Implantation in Refractory Glaucoma Patients at Sardjito General Hospital: Oral Presentation - Observational Study - Resident Saputra, Yuandani; Jati, Krisna Dwi Purnomo; Ekantini, Retno; Gani, Tatang T
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/2fz26x42

Abstract

Introduction & ObjectivesGlaucoma drainage device (GDD) implantation was an effective surgical procedure in treatinguncontrolled intraocular pressure (IOP) of glaucoma patients in certain complicated conditions. GDDimplants were classified into valved and non-valved in which its surgical outcomes in different typesof device and various etiologies were not similar. This study aimed to evaluate the surgery outcomesof GDD implantation in patients with refractory glaucoma at Sardjito General Hospital. MethodsAll 12 eyes of 11 patient’s medical records who underwent GDD implantation during 2022 at SardjitoGeneral Hospital was reviewed. Baseline data include age, gender, eye laterality, type of glaucoma,IOP and visual acuity. The IOP and visual acuity (LogMAR) were measured at week 1, month 1, 2and 3. Type of GDD implants, postoperative glaucoma medications, complications and need forfurther glaucoma surgery were documented. ResultsThe mean IOP at baseline was 44 ± 14.2 mmHg with 3.4 ± 0.6 glaucoma medications. It decreasedafter surgery into 19.1 ± 11.2 mmHg (p=0.003) at 3 months follow up with 0.7 ± 1.7 (p=0.002)glaucoma medications. The mean initial visual acuity was 1.9 ± 0.6 and changed insignificantly to1.7 ± 0.8 (p=0.624) at last follow up. Six eyes (50%) were implanted with valved implant. The mostcommon early postoperative complications were recurrent high IOP (4 eyes, 33.3%) associated toripcord of non-valved implant (p=0.025). Five eyes (41.7%) needed additional surgery related tonon-valved implant type (p=0.003). ConclusionGDD implantation especially valved type appears to be safe and effective surgical option in treatingrefractory glaucoma patients.
SECONDARY GLAUCOMA AFTER VITREORETINAL SURGERY: A RETROSPECTIVE OBSERVASIONAL STUDY: Oral Presentation - Observational Study - Resident Gunawan, Liani Mulasari; Rifada, R. Maula; Gustianty, Elsa; Umbara, Sonie
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/49ss4368

Abstract

Introduction & ObjectivesSecondary glaucoma is the most common complication after vitreoretinal surgery. Pars PlanaVitrectomy (PPV) is a common surgical procedure aimed at removing vitreous gel and replacing itwith variety of substances denominated tamponades. Vitreous removal and replacement may causeincreased intraocular pressure (IOP). The IOP can be reduced with medical treatment or surgery.The purpose of this study is to describe the characteristics of secondary glaucoma after vitreoretinalsurgery in National Eye Center Cicendo Hospital from January 2019 - December 2020. MethodsThis study was a retrospective descriptive study which data were obtained from medical records.Data such as age, gender, vitrectomy tamponades, IOP, onset of glaucoma, and glaucoma treatmentwere collected. ResultsOne hundred fifty-three eyes were referred to Glaucoma Unit with increasing IOP after vitreoretinalsurgery. PPV with tamponade was done in 141 eyes (92.16%) and silicone oil (SO) 1000 centistokes(cSt) was the most used tamponade in 101 eyes (66.07%). Secondary glaucoma with open angle wasthe most common type in 124 eyes (81.04%). Secondary glaucoma developed in 4-7 weeks aftersurgery, with the highest IOP recorded at 31-40 mmHg. The IOP decreased after SO evacuation withinitial glaucoma treatment in 121 eyes (79.09%), and glaucoma surgery was performed in 32 eyes(20.91%). ConclusionSilicon oil as a tamponade agent after PPV may cause rise IOP in the post-operative period.Evacuation SO needs to be done after retinal adhesion to prevent secondary glaucoma. Therefore,timely detection and anti-glaucoma treatment are important to decreased IOP, or filtration surgerycan be performed.
THE EFFECT OF ORAL VITAMIN D ON TUMOR NECROSIS FACTOR-? EXPRESSION IN TRABECULAR MESHWORK OF WISTAR GLAUCOMA MODEL: Oral Presentation - Experimental Study - Resident ERINA, RIKHA; Ariesti, Andrini; Hendriati
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/vrszrr85

Abstract

Introduction & ObjectivesElevated intraocular pressure (IOP) is a risk factor for the development and progression of glaucomathat can induces inflammation in the trabecular meshwork through the production of proinflammatorycytokines such as TNF-?. Inflammation induce mechanical stress and changes in theextracellular matrix in the trabecular meshwork, resulting in hypertonicity and resistance toaqueous humor outflow. Vitamin D can modulate cytokine production by suppressing TH1 cellexpression and inducing TH2 cell expression. The production of pro-inflammatory cytokines can besuppressed by the presence of vitamin D. MethodsAn experimental study of 30 wistar glaucoma model were divided into 3 groups, non treatmentgroup ( A and B) and the oral vitamin D (1200 IU/kg/day) group (C) for 14 days. TNF-? expressionsin trabecular meshwork were measured by immunohistochemical staining. Group A was measuredon day 3, while group B and C were measured on day 14. The differences between the three groupswere analyzed statistically using one way ANOVA test. Significantly different if the p<0.05. ResultsThe mean expression of TNF- ? in the trabecular meshwork of wistar glaucoma model in group A, B,and C was 22,2 ± 2,51%, 39,1 ± 3.98%, 34.2 ± 3,19 % respectively. There was significantlydifference in TNF-? expressions between the three groups (p<0.001). ConclusionVitamin D per oral can decrease TNF-? expression in the trabecular meshwork of wistar glaucomamodel on day 14 . Studies in wistar and humans are still needed to assess the effect of vitamin D onothers pro-inflammatory cytokines in glaucoma.
The Correlation between Retinal Nerve Fibre Layer Thickness, Optic Nerve Head Parameter, and Related Risk Factor in Glaucoma Patient: Oral Presentation - Observational Study - Resident Wardhana, Arif Kusuma; Ekantini, Retno; Gani, Tatang Talka; Jati , Krisna Dwi Purnomo
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/87d2ce77

Abstract

Introduction & ObjectivesTo investigate the correlation between retinal nerve fibre layer (RNFL) thickness and the past RNFLthickness, related risk factor (gender, age, myopia, intraocular pressure (IOP), blood pressure). AndRNFL parameter (symmetricity and four quadrants RNFL thickness) and optic nerve head parameter(rim area and vertical cup disc ratio) Methods39 right eyes of both sex and various age underwent examination including IOP measurement,subjective refraction for determining refractive error, and optical coherence tomography (OCT) forRNFL and ONH analysis. The follow up were done after one year. ResultsThe RNFL symmetricity, superior, nasal, inferior, temporal RNFL thickness showed significancecorrelation with RNFL thickness (R= 0.487, p= 0.002), (R= 0.915, R= 0.749, R= 0.897, R= 0.702with p= <0.001), but not showed significance correlation with rim area and vertical cup disc ratio(R= 0.175, p= 0.286) and (R= -0.093, p= 0.574). A significance correlation also showed withincreasing age, gender, and systolic blood pressure (R= -0.387, p= 0.015), (R= 0.441, p= 0.005) and(R= -0.418, p= 0.008). But not showed significance correlation with history of past RNFL thickness,refractive error, IOP, and diastolic blood pressure (R= 0.258, p= 0.113), (R= 0.005, p= 0.975), (R=-0.234, p=0.152), and (R= 0.060, p=0.717). ConclusionRNFL thickness measurements showed significance correlation with RNFL parameter. It is not clearif past RNFL thickness, refractive error and IOP related with RNFL thickness even showedsignificance correlation with age, gender, and systolic blood pressure.
The Outcomes of Trabeculectomy following Anti-VEGF Treatments in Neovascular Glaucoma : A Systematic Review and Meta-Analysis: Oral Presentation - Observational Study - General practitioner Dewi, Ni Putu Ayu Pande Arista
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/dyvqfy09

Abstract

Introduction Neovascular glaucoma (NVG) is a secondary glaucoma that potentially causes blindness due to proliferation of fibrovascular tissue in the anterior chamber angle. Ischemia in retinal triggers a cascade of various angiogenic factors including vascular endothelial growth factor (VEGF) and interleukin-6 which lead to neovascularization. It was known that anti-VEGF inhibits the primary mediators of neovascularization and control intraocular pressure (IOP) in NVG. Objective To summarize outcome of anti-VEGF with trabeculectomy and applied in clinical practice. Methods PRISMA guideline was followed and analyzed the comparison with Revman (version 5.4). We used databases and professional websites published on eye conditions between 2013-2023 in English. All interventional and observational studies with 95% confidence interval (CI) were used. Risk of bias was measured using funnel plot. Outcomes measured were IOP, Best Corrected Visual Acquity (BCVA), neovascularization iris (NVI) recurrence before and after trabeculectomy. Result Six studies (199 eyes) showed a significant difference in IOP (MD=25.84, 95%CI 24.08-27.60, p< 0.00001) and NVI recurrence (RD=0.94, 95%CI 0.86-1.01, p<0.00001). While four studies (143 eyes) found there was a significant difference in BCVA (MD=0.21, 95%CI 0.06-0.37, p=0.008). The result of NVI should be interpreted with caution and not considered as definitive statement since the data was moderately heterogenic (I2=68% p=0.009). Conclusion It could be concluded there was a significant difference in IOP, BCVA, and NVI recurrence after given anti-VEGF with trabeculectomy. We could not conclude which anti-VEGF gave better result since there were lack of studies, low of studies quality, and heterogen data for NVI recurrence.
INTRAOPERATIVE MITOMYCIN-C, 5-FLUOROURACIL, RETROBULBAR TRIAMCINOLON ACETONIDE, IS IT EQUALLY EFFECTIVE TO DECREASE INTRA OCULAR PRESSURE AFTER TRABECULECTOMY? Sari, Yessi Primanda; Ekantini, Retno; Gani, Tatang Talka; Jati, Krisna Dwi Purnomo
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/4e85px09

Abstract

Introduction & ObjectivesTo evaluate the effect of mitomycin-C (MMC), 5-fluorouracil (5-FU), and retrobulbar triamcinoloneacetonide (TA) on the surgical result of trabeculectomy. MethodsAll consecutive trabeculectomies with releasable sutures performed in Sardjito General Hospitalbetween January 2022 and December 2022 were retrospectively reviewed from medical records.Patients without any intraoperative metabolite (control group, n=5) were compared to those withretrobulbar TA (n=5), MMC group (n=19), and 5-FU group (n=11) in terms of surgical success.Successful surgery results were defined as IOP between 5 - 21 mm Hg without any furthermedications or surgical intervention and fewer complications. Results40 eyes of 35 patients (15 male, 25 female, mean age 52.4 years) were included in the study. Patientwas observed until post-operation day (POD) 90. There were no significant differences of intraocularpressure at POD 1, 7, 30, 60, and 90 between control group compared to TCA, MMC, and 5-FUgroup. Intraocular pressure pre- and post-operation in each group was significantly different(p<0.05). The lowest mean intraocular pressure of POD 90 was in 5-FU group (13.64 ± 4.08).Complication after trabeculectomy in TCA group was 21%, MMC group was 27%, 5-FU group was10%, and control group was 42%. ConclusionMMC, 5-FU, and TCA in this study are equally effective to decrease IOP after trabeculectomy.
Relationship Between Mean Deviation Slope with Related Risk Factors and Foveal Sensitivity of Humphrey Field Analyzer Test in Open Angle Glaucoma: Oral Presentation - Observational Study - Resident Rizki, Hanis Fatkhul; Gani, Tatang Talka; Ekantini, Retno; Jati , Krisna Dwi Purnomo
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/hcfjcs46

Abstract

Introduction & ObjectivesTo analyze relationship between mean deviation (MD) slope with related risk factors and fovealsensitivity of Humphrey field analyzer (HFA) in open angle glaucoma. Patient and MethodsThis study was retrospective and consecutive sampling during a year follow up period in SardjitoGeneral Hospital. A total 95 eyes from 95 patient were exemained the MD slope by HFA (SITAstandard, 24-2 program) being follow up and compared first examination with the final VF test.Relation of MD slope with risk factors and HFA parameters were correlatively analyzed. ResultsMean Deviation slope was observed in 48/95 patients (50.52 %) and no progression was observed in47/95 patients (49.47 %). The related risk factors gender, age, spherical equivalent and IOP do notshowed significant correlation with MD slope (R= 0.02, P= 0.89), (R=0.10, p=0.47), (R=-0.27, p=0.06) and (R=-0,13, p= 0.35). Foveal sensitivity test in HFA parameter do not showed significantcorrelation with MD slope (R= 0.14, p=0.32). ConclusionWorsening value of spherical equivalent and IOP showed negative correlation to MD slope, butstatistically do not showed significant correlation caused there are not much differences betweenprogress and non progress group.
A systematic review comparing Mytomicyn-C subtenon injection to sponge during trabeculectomy in open angle glaucoma: Oral Presentation - Observational Study - General practitioner Ethelind, Rachel; Puspa, Prizka Avilia; Santoso, Wildan Iman
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/x94ab172

Abstract

Introduction & ObjectivesMitomycin-C (MMC) is an effective agent to prevent scarring during the healing process followingtrabeculectomy procedure by inhibiting the multiplication of cells producing scar tissue. The aim ofthis study is to compare the efficacy of Mitomycin-C (MMC) delivered by either subtenon injection orsponge application during trabeculectomy surgery in open angle glaucoma patients. MethodsA systematic search was done using several databases including Pubmed, Medline, Embase, Scopus,and Jstor. Inclusion criteria were open angle glaucoma patients underwent trabeculectomy surgery,given either MMC via subtenon or sponge application, article in English, Randomized ControlledTrial (RCT) studies which published in the last 10 years. Intra-Ocular Pressure (IOP), EndothelialCell Counts (ECC) and Bleb Morphologic features with at least 1 month follow-up were evaluated. ResultsTwo RCT studies were included in this study. Both studies demonstrated that sub-tenon injectionand sponge application has no significant difference regarding IOP reduction from the baseline.Regarding morphologic features, both studies favor subtenon to conventional sponge application.Lastly, ECC in both studies conclude that there was no marked differences. ConclusionThe outcome of administration of MMC through subtenon injection and sponge application werecomparable to one another. However, less vascularization are shown in subtenon injection group.
CORRELATION BETWEEN PLATELET PARAMETERS AND THE SEVERITY OF PRIMARY OPEN ANGLE GLAUCOMA Gunanegara, Abdi Sastra; Yuliawati, Putu; Kusumadjaja, I Made Agus
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/x2jvs545

Abstract

Introduction & ObjectivesPrimary open angle glaucoma (POAG) is a chronic optic neuropathy characterized by slowlyprogressive visual function loss. Platelet activation as well as its interaction with vascularendothelium and plasma components, play an important role in the vascular pathophysiology ofPOAG. Platelet aggregation in glaucoma tends to increase. This change has negative impact on smallvessel circulation in the eye, such as branches of short ciliary arteries supplying the optic nerve. Inthis study, we will assess the correlation between platelet parameters and the severity of POAG. MethodsThis study is an analytical observational study. Data were obtained retrospectively and prospectivelywith a cross sectional study approach conducted at Sanglah Hospital, Denpasar. The study samplewas 62 eyes selected consecutively. Data was analyzed using SPSS. Descriptive data presentednumerically or categorically, bivariate analysis using Pearson and Spearman correlation tests andmultivariate analysis using logistic regression. ResultsResults showed that the mean age of the research subjects was 66.71 ± 9.795 years, with themajority was male (70.6%). Bivariate analysis, showed no significant correlation between plateletparameters (PLT, PDW, MPV) and the severity of POAG. Multivariate analysis found that age ? 68years, 9,850 times more likely to develop moderate to severe glaucoma, compared to patients < 68years old (OR 9,850, 95% CI, p = 0.009). ConclusionPlatelet parameters showed no significant correlation with the severity of POAG, meanwhile olderage is more at risk of developing moderate to severe POAG.

Page 36 of 87 | Total Record : 869

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