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intan juniarmi
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Journal of Pharmacopoeia
Published by PT Anagata Sembagi Education
ISSN : -     EISSN : 30474469     DOI : 10.62872/cgkqdb72
Core Subject : Health, Education,
Medicine & Pharmacology Veterinary Other
Journal of Pharmacopoeia is an international peer-reviewed and open access journal established to invite scientists and educators around the world to exchange and disseminate theory and practice orientated pharmaceuticals. All submitted manuscripts will be reviewed by the editors and then evaluated by a minimum of two International Reviewers through a double-blind review process. This is to ensure the quality of manuscripts published in the journal.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 20 Documents
 1   2 
Use of Kaolin in the Pharmaceutical and Cosmetic Industries Nurul Fadhilah
Journal of Pharmacopoeia Vol. 1 No. 1 (2024): MARET-JP
Publisher : Pt. Anagata Sembagi Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62872/0wbz8c85

Abstract

Kaolin, a white clay mineral composed mainly of kaolinite with the chemical formula Al2O3.2SiO2.2H2O, has been a subject of interest since the days of medieval western literature. This interest increased especially after the advent of a more empirical approach to pharmacology, the establishment of pharmacopoeias, and developments in mineralogy, chemistry, as well as pharmaceutical technology. The use of kaolin in pharmaceutical (both topical and oral) and cosmetic applications has become important. Although it has long been recognized as a remedy in traditional medicine, the use of kaolin as an active ingredient for various diseases continues to be researched. Unfortunately, research focused on the use of kaolin in pharmaceuticals and cosmetics is still fairly limited. Therefore, this article aims to highlight the role and benefits of kaolin in both fields. Kaolin has been shown to have antibacterial, antiviral, and antidiarrheal properties when administered orally, as well as serve as a skin-protective agent when used topically. Aside from being an active ingredient, kaolin is also often used as an excipient in pharmaceutical formulations, acting as a filler, emulsifier, suspending agent, and crusher. In the cosmetic world, kaolin is often used as a sunscreen and to treat the skin. This article is organized based on a literature review of various articles and journals relevant to the topic discussed.
Assessment of Pediatric Skin Patient Satisfaction with Pharmacy Services at Basmalah Clinic Jambi Sefiani Dwi Azmi
Journal of Pharmacopoeia Vol. 1 No. 1 (2024): MARET-JP
Publisher : Pt. Anagata Sembagi Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62872/kk38m017

Abstract

The purpose of this study is to evaluate the level of satisfaction of pediatric skin patients with the pharmaceutical services provided at the Basmalah Jambi Clinic. The clinic is known as a primary health care provider in Jambi city and has a pharmacy unit that provides medicines for patients. Methods The research conducted was descriptive with an observational approach. The observational method is a collection technique on research subjects. The qualitative method in the study of Pediatric Satisfaction Assessment of Pharmaceutical Services at the Basmalah Jambi Clinic refers to a research approach that focuses on an in-depth understanding of patients' experiences, perceptions, and views of the pharmaceutical services they receive at the clinic. The results of this study indicate that pharmaceutical services at the Basmalah Jambi Clinic have met the needs and expectations of pediatric skin patients in general. However, there are some areas that need to be improved to enhance service quality and ensure continued patient satisfaction in the future.
The Role of Traditional Medicines as Chemopreventive and Suppressive Agents in Cancer Treatment Deanova Insiratu Nurul Andini; Gilang Kurniawan; Nahla Akila Fikria
Journal of Pharmacopoeia Vol. 1 No. 1 (2024): MARET-JP
Publisher : Pt. Anagata Sembagi Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62872/yhfqm859

Abstract

The purpose of this study was to determine the role of traditional medicine as a chemopreventive and suppressive agent in the treatment of Deanova Insiratu Cancer. This study is a qualitative study, this study will use a retrospective and prospective observational approach. Data will be collected from the medical records of patients who have used Deanova Insiratu previously, as well as from direct observation and interviews with individuals who are currently using or have experience with this traditional medicine.  Research Results Cancer or malignant tumors can occur due to the growth of body tissue cells that proliferate abnormally. Cancer prevention can be done with healthy living habits and avoiding risk factors that can cause cancer. Cancer treatment can be done in 4 ways, namely by surgery, radiotherapy, immunotherapy and chemotherapy. Cancer screening can be done with mammography, ultrasonography (USG), and Magnetic Resonance Imaging (MRI). Natural ingredients that have effects as cancer prevention and help cancer treatment include Soursop leaves (Annona muricata), Celery leaves (Apium graveolans linn), Red Atai Spike leaves (Angiopteris ferox copel), Benalu Kepel (Dendrophthoe pentandra (L.) Miq.), and Tapak Dara leaves (Catharanthus roseus).
Nanoteknologi Farmasi Ziprasidone Nanocrystals By Wet Media Milling Followed By Spray Drying AndLyophilization: Formulation And Process Parameter Optimization Mutiara Deas Tantia; Nahla Akila Fikria; Vio Agister Risanl
Journal of Pharmacopoeia Vol. 1 No. 1 (2024): MARET-JP
Publisher : Pt. Anagata Sembagi Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62872/n14vp920

Abstract

lyophilisation. The research methods used include the preparation of Ziprasidone nanosuspension using size reduction technique, optimisation of process parameters, formulation of media milling technique, and evaluation of the physical stability of the optimised nanosuspension. The results of this study are expected to provide a better understanding of the use of nanocrystals in improving the solubility and bioavailability of drugs with poor solubility such as Ziprasidone. In addition, this study is also expected to provide new insights into the use of spray drying and lyophilisation technologies to improve the physical stability of drug nanosuspensions. In conclusion, this study highlights the importance of using nanocrystals in improving the solubility and bioavailability of drugs with poor solubility such as Ziprasidone. Spray drying and lyophilisation methods have been shown to be effective in improving the physical stability of drug nanosuspensions. This research can serve as a foundation for the development of more effective drug formulations that can be used in wider clinical applications.
Biofarmasetics and Pharmacokinetics Study Analysis of Paracetamol Excretion Through Urine and Saliva Nahla Akila Fikria
Journal of Pharmacopoeia Vol. 1 No. 1 (2024): MARET-JP
Publisher : Pt. Anagata Sembagi Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62872/ct7faz89

Abstract

The purpose of this study was to determine that Paracetamol, also known as acetaminophen, is a commonly used analgesic and antipyretic drug to relieve pain and reduce fever. The process of metabolism and elimination of paracetamol from the body is important to understand, especially in the context of the safe use of this drug. This study aims to analyze the biopharmaceutics and pharmacokinetics studies of paracetamol excretion through urine and saliva as important indicators in understanding the metabolic and elimination processes of this drug. Paracetamol is rapidly and efficiently absorbed through the gastrointestinal tract, reaches the highest concentration in plasma in a short time, and is dispersed throughout the body fluids. The metabolic process of paracetamol mainly occurs in the liver, through two main phases: oxidation and conjugation with glucuronic and sulfuric acids.  Excretion of drugs and their metabolites can occur through urine and saliva, with the kidney as the main organ in the excretion process. Qualitative analytical methods were used in this study to identify paracetamol metabolite compounds in urine and saliva samples and to evaluate the metabolic pathways involved. Glucoronide, sulfate, and phenol conjugate assays were used to detect the presence of paracetamol metabolites in the samples. The assay results showed that urine was more effective in excreting paracetamol compared to saliva. In conclusion, this study provides a better understanding of the metabolic process and elimination of paracetamol from the human body through the analysis of biopharmaceutics and pharmacokinetics studies. These results are important for understanding the therapeutic effects and toxicity of paracetamol as well as for developing more effective and safe drug use management strategies.
Effectiveness of Soursop Leaf Extract in Reducing Glucose Levels in Diabetes Mellitus Patients: Literature Study Elisa Issusilaningtyas; Nikmah Nuur Rochmah
Journal of Pharmacopoeia Vol. 1 No. 2 (2024): SEPTEMBER-JP
Publisher : Pt. Anagata Sembagi Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62872/36x6v823

Abstract

Alternative treatment for lowering sugar levels can be done through the use of herbal plants such as soursop leaves. This study aims to evaluate the effectiveness of soursop leaf extract (Annona muricata L.) in reducing blood glucose levels in Diabetes Mellitus (DM) patients. This research uses a literature study method, with data taken from scientific articles or journals within the last five years. Data was collected using the Google Scholar search engine with the keywords "diabetes mellitus," "soursop leaf extract," and "reducing sugar levels". Research shows that soursop leaf extract (Annona muricata L.) contains flavonoids, tannins, alkaloids, and saponins which are effective in lowering blood glucose levels through various mechanisms, including inhibiting sugar absorption, increasing glucose tolerance, stimulating insulin release, and regulating carbohydrate metabolism enzymes. The results of clinical and in silico trials support the effectiveness of this extract, making it a potential herbal treatment alternative amidst the current high costs of diabetes care. This research encourages the use of soursop leaves as a promising therapy and recommends further research to optimize its benefits.
Pharmaceutical involvement in Infectious Disease control: Strategies, Challenge and Solutions Norma Winata; Dadang Muhammad Hasyim; Brevmana Anugrah Primulyanto
Journal of Pharmacopoeia Vol. 1 No. 2 (2024): SEPTEMBER-JP
Publisher : Pt. Anagata Sembagi Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62872/rtag4g06

Abstract

This study aims to explore the role of the pharmaceutical sector in controlling infectious diseases, focusing on strategies, challenges, and solutions that can be implemented. The research method used is Systematic Literature Review (SLR) to collect and analyze data from related literature. Inclusion criteria include articles published in the last ten years, using English or Indonesian, and discussing pharmaceutical strategies in controlling infectious diseases. The literature search process was carried out through scientific databases such as PubMed, Scopus, and Google Scholar. The results of this study are Infectious disease control strategies involve the development of new vaccines and drugs, efficient drug distribution, and public education. The pharmaceutical sector plays an important role in creating medical solutions and implementing vaccination campaigns. The main challenge is antimicrobial resistance, which is caused by the unwise use of antibiotics. To overcome this challenge, public education, strict supervision in health facilities, and the development of new drugs are needed. The application of digital technology, such as AI-based applications, can also help monitor drug use and provide early warnings about the spread of disease. The role of pharmacists is vital in providing information and education about disease prevention, correct drug use, and the importance of vaccination. With innovative solutions such as the development of emergency pharmaceutical packages, the implementation of e-prescription, and technology-based training for pharmacists, it is hoped that the global health system can be more resilient in dealing with infectious disease outbreaks. Collaboration between the pharmaceutical sector, governments, and international organizations is essential in strengthening infectious disease control efforts and improving the readiness of the global health system.
Evidence-Based Pharmacy: Integration of Data and Research in the Development of more Effective and Safer Drugs Dadang Muhammad Hasyim; Liza Rastiti
Journal of Pharmacopoeia Vol. 1 No. 2 (2024): SEPTEMBER-JP
Publisher : Pt. Anagata Sembagi Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62872/29d66p06

Abstract

The main objective of this study was to collect, evaluate, and synthesize findings from relevant studies on the use of evidence-based data in drug development. The method used was a Qualitative Systematic Literature Review (SLR), which focused on understanding in-depth how the integration of data from clinical trials, big data, and laboratory studies can improve drug efficacy and safety. Through this approach, the study identified experiences, perceptions, and findings in the literature on drug development, and how this evidence supports decisions in drug selection and testing. The results showed that evidence-based pharmacy has great potential to improve the efficacy and safety of therapies by leveraging the integration of data from various sources and advanced analytical technologies. This approach can address key challenges in modern pharmacy, such as drug resistance and patient response variability, and result in more personalized and effective therapies. However, the implementation of evidence-based pharmacy requires support from various stakeholders, including academia, industry, and policy makers. Challenges such as data interoperability and privacy protection need to be addressed to ensure wider adoption. With a strategic and collaborative approach, evidence-based pharmacy can be the foundation for better precision medicine in the future, providing significant benefits to patients worldwide.
Ethics and Responsibility in Pharmaceutical Practice: Facing Moral Dilemmas in the Modern Era Imam Jayanto; Untung Gunawan; Moh. Yaqya
Journal of Pharmacopoeia Vol. 1 No. 2 (2024): SEPTEMBER-JP
Publisher : Pt. Anagata Sembagi Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62872/eec2e850

Abstract

Pharmacy practice plays a crucial role in the modern healthcare system, providing access to safe and effective medicines for the public. However, in carrying out their profession, pharmacists are often faced with complex moral dilemmas. The modern era, with technological advances and commercial pressures, further complicates ethical decision-making. This article aims to examine ethical responsibilities in pharmacy practice and how pharmacists deal with conflicts of interest between economic gain and patient interests. Using a Systematic Literature Review (SLR) approach, this study identifies the main challenges faced by pharmacists in maintaining professional integrity while meeting regulatory demands and social expectations. The results suggest that pharmacists must adopt a balanced, value-based approach, where priority is given to patient welfare without neglecting the business aspects that are an integral part of healthcare. The discussion also explains the importance of developing ethical guidelines that are adaptive and relevant to the challenges of the digital era. The conclusion of this study is that a collaborative approach between government, professional organizations, and educational institutions can help create a stronger framework to support pharmacists in dealing with moral dilemmas in the workplace.
Pharmacological Effects of Curcumin in Chronic Inflammatory Therapy Muntasir, Muntasir; Faradina, Anggia; Wuryandari, Tutik; Cendekiawan, Khrisna Agung
Journal of Pharmacopoeia Vol. 2 No. 1 (2025): MARCH-JP
Publisher : Pt. Anagata Sembagi Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62872/r1y2wm33

Abstract

Herbal plants Herbal plants in Indonesia have an important role in traditional medicine and public health. The study aims to evaluate the effectiveness and mechanism of action of curcumin in chronic inflammatory therapy. This study employs the Systematic Literature Review (SLR) methodology.. This study uses a database from Scopus of 9 Scopus articles from the range of 2020 to 2025. There are three stages carried out in mapping the effectiveness and mechanism of action of curcumin in chronic inflammatory therapy, namely data harvesting, screening data and Data Analysis and Visualization. The results obtained are that curcumin is effective in chronic inflammatory therapy by inhibiting the main inflammatory pathways (NF-ƙB and JAK/STAT), has antioxidant effects, accelerates tissue regeneration, and functions as an immunomodulator. However, the limited bioavailability of curcumin presents a significant challenge in its application. Nanoformulation technology and its combination with compounds like CMPs can enhance its effectiveness in clinical therapy.The implications of this research are directed to researchers, the community and the government

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