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Lombok Medical Journal
Published by Universitas Mataram
ISSN : -     EISSN : 28277686     DOI : -
Core Subject : Health, Science, Engineering,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Mechanical Engineering Public Health
Lombok Medical Journal (LMJ) is a peer-reviewed and open access journal that focuses on promoting medical sciences generated from basic sciences, clinical, community or public health research, and medical education to integrate researches in all aspects of human health. This journal publishes original articles, reviews, and case reports. Brief communications containing short features of medicine, latest developments in diagnostic procedures, treatment, or other health issues that is important for the development of health care system are also acceptable. Focus and Scope of Lombok Medical Journal (LMJ): Basic Science, Clinical Research, Community or public health research, Medical Education
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 156 Documents
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Tenosynovial Giant Cell Tumor pada Wanita Usia 32 Tahun : Sebuah Laporan Kasus Ilham, Lalu Fahril; Lalu Fauzan Adi Yuliansyah
Lombok Medical Journal Vol. 3 No. 3 (2024): Lombok Medical Journal Volume 3 Nomor 3
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v3i3.3655

Abstract

Tenosynovial giant cell tumors are a group of benign soft tissue tumors of synovial origin with characteristic histologic features. In general, based on the growth pattern, it can be divided into local and diffuse types, and based on the location of the growth, it can be divided into intra-articular and extra-articular. Local type tumors generally develop slowly, while diffuse type tumors develop more aggressively and often affect the patient's quality of life. Recent developments show that tenosynovial giant cell tumor is a clonal neoplastic tumor driven by overexpression of Colony Stimifying Factor 1 (CSF1) in the synovial area, thus forming a mass. In this case report, we report a case of localized tenosynovial giant cell tumor and recent developments regarding its pathogenesis.
Endovaskular Repair pada Isolated Stabil Ruptur Aneurisma Arteri Iliaka : Sebuah Laporan Kasus Langka Ilham, Lalu Fahril; Sanditias Putrawan; I Made Arya Winata; Arif Zuhan; I Komang Yose Antara; Muhammad Farizka Firdaus; Mervin Arifianto Manginte
Lombok Medical Journal Vol. 3 No. 3 (2024): Lombok Medical Journal Volume 3 Nomor 3
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v3i3.3657

Abstract

An iliac aneurysm is a bulging and weakness in the wall of the iliac artery, a group of arteries located in the pelvis. The development of the disease is not progressive and the diagnosis is often accidental. In some cases, the diagnosis is made after complications occur, the most serious of which is aneurysm rupture. Intervention for a ruptured aneurysm can cause total circulatory collapse and has a high risk of perioperative morbidity and mortality ≤50%. The incidence of this case is around 0.4% of all abdominal aneurysms. This case is a challenge to handle because the anatomical location and surgical procedure are considered difficult. Open surgery and endovascular intervention are the definitive therapies for iliac artery aneurysms.
Keamanan Kontrasepsi Hormonal sebagai Faktor Risiko Meningioma Briliansy, Briliansy; Harahap, Herpan Syafii
Lombok Medical Journal Vol. 3 No. 1 (2024): Lombok Medical Journal Volume 3 Nomor 1
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v3i1.3661

Abstract

Meningioma, yang timbul dari meningen, merupakan tumor otak primer yang paling umum terjadi pada orang dewasa. Meskipun sebagian besar bersifat sporadis, faktor genetik, termasuk mutasi pada gen berkontribusi terhadap perkembangannya. Tinjauan ini mengeksplorasi interaksi yang kompleks antara pengaruh genetik dan lingkungan terhadap patogenesis meningioma, menekankan perlunya penilaian risiko dan konseling genetik. Selain itu, tinjauan ini juga menggali potensi hubungan antara penggunaan kontrasepsi hormonal, khususnya estrogen dan progestin, dengan risiko meningioma. Studi epidemiologi memberikan temuan yang beragam, dengan beberapa di antaranya menunjukkan peningkatan risiko yang tidak terlalu besar, terutama di antara pengguna jangka panjang. Adanya reseptor hormon pada meningioma menggarisbawahi pengaruh hormon terhadap pertumbuhan tumor. Namun, bukti-bukti yang ada belum meyakinkan, sehingga memerlukan interpretasi yang hati-hati dan menyoroti pentingnya penelitian lebih lanjut untuk memperjelas hubungan ini. Berdasarkan bukti-bukti yang ada, makalah ini merekomendasikan penilaian individual terhadap risiko dan manfaat penggunaan kontrasepsi hormonal, terutama bagi perempuan dengan riwayat meningioma atau faktor risiko lainnya. Penelitian yang sedang berlangsung sangat penting untuk pengambilan keputusan yang tepat dalam kesehatan reproduksi.
The Karakteristik Anemia pada Pasien Hemodialisis Rutin di RSUD Provinsi NTB : Karakteristik Anemia pada Pasien Hemodialisis Rutin di RSUD Provinsi NTB Ni Putu, Yunandari; Ima Arum Lestarini; I Gede Yasa Asmara3
Lombok Medical Journal Vol. 3 No. 1 (2024): Lombok Medical Journal Volume 3 Nomor 1
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v3i1.3693

Abstract

Abstract Background: The most common complication in End Stage Renal Disease (ESRD) undergoing hemodialysis (HD) is anemia. Anemia increases mortality and morbidity. This study aims to determine the characteristics of anemia in ESRD patients undergoing HD. Method: This research is a cross-sectional observational analytical study and the sample is ESRD patients undergoing HD at the NTB Provincial Regional Hospital in 2021, taken consecutively. Data came from medical records and were analyzed univariately and bivariately using the Chi-Square test. Result: The prevalence of anemia in HD patients was 66.3%. Characteristics of ESRD patients undergoing HD include female gender (52.7%), middle age (61.4%), anemia (71.9%), mild anemia (72.7%), normocytic morphology (77.3%), normal serum iron (79.1%), normal TIBC (99.1%), and normal ferritin (82.7%), received iron therapy (29.1%), received erythropoietin (EPO) (86.4%), and had a blood transfusion (15.5%). In bivariate analysis, it was found that there was no significant relationship between the incidence of anemia and gender (p=0.084) and age (p=0.980). There was no relationship between the degree of anemia and iron therapy (p=0.672). There was a significant relationship between the degree of anemia with EPO therapy (p<0.001), and the degree of anemia with blood transfusion (p<0.001). Conclusion: The characteristics of anemia in regular HD patients are dominated by men, middle-aged adults, mild anemia, normocytic morphology, normal iron status, and the therapy given includes serum iron, EPO, and blood transfusions. Keywords: anemia, hemodialysis, characteristics
Tata Laksana Diabetes Melitus Tipe 1 dengan Ketoasidos Diabetik pada Anak 7 Tahun dengan Sindrom Down dan Gizi Buruk di Rumah Sakit dengan Layanan Terbatas: Case Report Padmita Utami, Ida Ayu; William Cheng; Ni Made Reditya Noviani
Lombok Medical Journal Vol. 3 No. 2 (2024): Lombok Medical Journal Volume 3 Nomor 2
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v3i2.3695

Abstract

The incidence of children with Type-1 Diabetes Mellitus (T1DM) is increasing both worldwide and in Indonesia. The Indonesian Pediatric Society (IPS) recorded 1120 pediatric patient with T1DM in 2018. Potential complication of type 1 DM is Diabetic ketoacidosis (DKA). Diabetic ketoasidosis is a terminal condition in metabolic abnormalities caused by severe insulin deficiency. Patients with Down syndrome (DS) have an increased risk of developing autoimmune diseases such as Type 1 Diabetes Mellitus (T1DM). This is a rare case of a Down Syndrom patient with a clinical profile of severe malnutrition, which can lead to serious complication.
A Gambaran Kadar Asam Urat pada Pasien Hemodialisis rutin di RSUD Provinsi NTB: Gambaran Kadar Asam Urat pada Pasien Hemodialisis rutin di RSUD Provinsi NTB Miraditi, Ni Komang Miraditi; I Gede Yasa Asmara; Raehanul Bahraen
Lombok Medical Journal Vol. 3 No. 3 (2024): Lombok Medical Journal Volume 3 Nomor 3
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v3i3.3716

Abstract

According to the United States Renal Data System, there were 124,411 patients with end-stage renal disease (ESRD) in 2015, and the number is estimated to increase by 20,000 cases per year. The decline in kidney function in ESRD patients leads to various clinical conditions, one of which is an increase in blood uric acid levels. Studies on patients who have not undergone hemodialysis (HD) found that 86.7% of patients experienced hyperuricemia, compared to 73.3% of patients who had already undergone HD. This study aims to describe the uric acid levels in ESRD patients undergoing HD at the NTB Provincial Hospital. This research used an analytical observational method with a cross-sectional study design based on secondary data (medical records) of ESRD patients undergoing HD at the NTB Provincial Hospital from January to August 2021. The sampling technique used was consecutive sampling. The data obtained were then analyzed using the Statistical Package for Social Sciences (SPSS). Among the 127 samples, the average uric acid level in HD patients was found to be 8.0 mg/dl, with 83 patients (65.4%) having hyperuricemia. More male patients (43 or 51.8%) had hyperuricemia compared to female patients (40 or 48.2%), and the highest incidence of hyperuricemia was found in patients aged 40-59 years, accounting for 67.5%. Bivariate chi-square analysis showed no significant association between uric acid levels and gender (p=0,590), age (p=0,152), duration of HD (p=0,730), or history of anti hyperuricemic treatment (p=0,613). This study concludes that the incidence of hyperuricemia in HD patients is high. Uric acid levels are not associated with age, gender, duration of hemodialysis, or history of anti-hyperuricemic treatment.
Peran Neurorestorasi pada Pasien Post Stroke Susilawati, Ni Nyoman Ayu; Rizqi Al Kasiron; Hidzul Mahidza Falah; Rizkia Wiyani Putri; Siska Julia Cindy W; Herpan Syafii H; Catur Ari Setianto
Lombok Medical Journal Vol. 3 No. 3 (2024): Lombok Medical Journal Volume 3 Nomor 3
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v3i3.3960

Abstract

Stroke penyebab utama kecacatan dan kematian ketiga setelah penyakit jantung dan keganasan (Feigin dkk, 2022). Prevalensi stroke di Indonesia (Riskesdas 2018) meningkat 56% dalam 5 tahun (7 kasus/1000 penduduk tahun 2013 menjadi 10,9 kasus/1000 penduduk tahun 2018). Dengan meningkatnya harapan hidup dan faktor risiko stroke, perkiraan jumlah penderita stroke mencapai lebih dari 1 juta orang pada tahun 2050 (Dirjen Yankes, 2024). Neurorestorasi merupakan proses untuk memulihkan, meningkatkan, atau mempertahankan integritas fungsi neurologis dengan strategi neurorestoratif, termasuk fisik (elektronik atau magnetik), kimiawi (obat atau agen kimia), biologis (terapi sel, molekul, bioteknologi, dan rekayasa jaringan), bedah, atau jenis intervensi lainnya, yang dapat memulihkan struktur dan/atau fungsi saraf secara bersamaan. Mekanisme neurorestoratif dalam sistem saraf pusat (SSP) meliputi neuroprotektif, neuromodulasi, neuroplastisitas (neurosinapsis, sirkuit saraf, atau rekonstruksi jaringan), imunomodulasi, regenerasi aksonal, remielinasi, neuroregenerasi (neurogenesis) dan angiogenesis (Huang dan Chen, 2015; Gunduz dkk, 2023).Berbagai metode terapi neurorestorasi dan neurorehabilitasi pasca stroke dapat digunakan meningkatan neuroplastisitas seperti non invasive brain stimulation repetitive transcranial magnetic stimulation (rTMS), transcranial direct current stimulation (tDCS), terapi Stem cell, deep brain stimulation, virtual reality (VR), terapi musik, terapi kovensional seperti terapi fisik, terapi wicara. Terapi kombinasi berbagai modalitas terapi ini terbukti lebih signifikan memberikan hasil yang lebih baik dibandingkan terapi tunggal atau terapi konvensional
Faktor Predisposisi Stigma dan Diskriminasi serta Upaya Peningkatan Kualitas Hidup Pasien terdiagnosis HIV/AIDS Ni Wayan Puspa Wijaya Suryantarini
Lombok Medical Journal Vol. 3 No. 2 (2024): Lombok Medical Journal Volume 3 Nomor 2
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v3i2.3990

Abstract

HIV/AIDS menjadi salah satu kondisi yang menemui hambatan dalam upaya peningkatan kualitas hidup pasien yakni dengan masih berkembangnya stigma dan diskriminasi HIV/AIDS di kalangan masyarakat. Di samping progresi penyakit yang berdampak terhadap kesehatan fisik dan kehidupan sosial pasien, tekanan akibat stigma dan diskriminasi mengisolasi pasien dengan perasaan takut dan stres yang berlebihan. Masyarakat memiliki sejumlah karakteristik yang menjadi faktor predisposisi munculnya stigma dan diskriminasi tersebut. Peran menyeluruh sektor kehidupan dalam memerangi gejolak stigma dan diskriminasi akan sangat membantu mempercepat penyembuan pasien termasuk memberikan kehidupan yang lebih baik bagi pasien terdiagnosis HIV/AIDS. Dukungan masyarakat dapat berupa peningkatan kesadaran dan pengetahuan melalui sosialisasi, komunitas, dan kampanye terkait HIV/AIDS. Tinjauan pustaka ini merangkum sejumlah bentuk stigma dan diskriminasi yang kerap dihadapi pasien terdiagnosis HIV/AIDS, faktor-faktor di masyarakat yang berhubungan dengan hal tersebut, serta faktor dan upaya peningkatan kualitas hidup pasien melalui penghapusan stigma dan diskriminasi dengan dukungan dari pemerintah, pelayanan kesehatan, dan masyarakat umum.
Visual Impairment in High Flow Carotid-Cavernous Fistula: Case Report Putri, Setyawati Asih; Wiracakra, I Gusti Lanang Krisna
Lombok Medical Journal Vol. 3 No. 2 (2024): Lombok Medical Journal Volume 3 Nomor 2
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v3i2.4499

Abstract

Carotid-cavernous fistula (CCF) is the most common abnormal connection between the carotid artery and the cavernous sinus. There are 2 types of CCF: direct and indirect. Direct CCF is a high-flow fistula that occurs due to a tear in the carotid artery, most often caused by penetrating or nonpenetrating head trauma. Visual disturbances can be one of the symptoms of CCF in post-traumatic patients. With proper diagnosis and management, the patient's condition can significantly improve. A 22-year-old man came with symptoms of bilateral chemosis and bilateral proptosis, which had developed progressively for 1 month. The patient had a history of a traffic accident 2 months before with mandibular trauma. The patient had undergone mandibular surgery, but at that time, no neurological symptoms had appeared. Physical examination revealed bilateral chemosis, bilateral proptosis, blurred vision and oftalmoplegi with diplopia. Magnetic Resonance Angiography (MRA) of the head showed features that led to a diagnosis of carotid-cavernous fistula. Cerebral angiography was performed and confirmed there was a high-flow carotid-cavernous fistula. Endovascular intervention was performed, and a decision was made to perform balloon embolization. Four months after the procedure, the patient's complaints improved, blurred vision decreased, and proptosis disappeared. Based on this case report, carotid-cavernous fistula can be used as a differential diagnosis for the cause of visual impairment in post-head trauma patients. Appropriate management can treat the patient's clinical symptoms
Patofisiologi Ensefalitis pada Rabies Wahyudi, Safat; Landapa, Raditya Rachman
Lombok Medical Journal Vol. 3 No. 2 (2024): Lombok Medical Journal Volume 3 Nomor 2
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v3i2.4527

Abstract

Rabies, disebabkan oleh Rabies Lyssavirus, virus neurotropik yang menargetkan neuron dan menyebar sepanjang sel saraf, menghasilkan disfungsi neuronal. Virus ini menunjukkan neurotropisme dan neuro-invasivitas yang kuat, menyebabkan manifestasi neurologis yang parah. Penularan penyakit ini biasanya melalui gigitan hewan yang terinfeksi, memungkinkan virus masuk ke dalam tubuh dan bereplikasi sebelum mencapai otak atau medula spinalis. Rabies muncul dalam dua bentuk yang berbeda, yaitu ensefalitik dan paralitik, dengan rabies ensefalitik lebih umum dan ditandai dengan gejala klasik seperti hidrofobia dan aerofobia. Tanda-tanda awal dapat mencakup kesemutan pada anggota tubuh tanpa gangguan kognitif. Pemahaman terhadap patofisiologi serta interaksi antara virus Rabies dan host, antara lain mekanisme masuknya virus, replikasi, dan penyebaran dalam sistem saraf sangat penting untuk menjelaskan tentang proses perjalanan penyakit, termasuk perubahan perilaku yang terjadi. Pencegahan rabies melibatkan vaksinasi yang tepat waktu setelah paparan, sementara pengobatan pasca-infeksi yang adekuat hingga saat ini masih menjadi tantangan.

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