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Frontiers on Healthcare Research
ISSN : 30327725     EISSN : -     DOI : https://doi.org/10.63918/fhr.v2.n2
Core Subject : Health,
The principal aim of Frontiers on Healthcare Research is to catalyze advancements in healthcare research that directly inform and improve the efficacy of health system operations, enrich patient experiences, and guarantee fairness in health service access
Articles 44 Documents
Socioeconomic Status and Healthcare Support on Anti-Tuberculosis Medication Adherence Among Pediatric Tuberculosis Patients Sari, Nissa Prima
Frontiers on Healthcare Research Vol. 2 No. 1 (2025)
Publisher : Rumah Sakit Umum Pusat (RSUP) Dr. M. Djamil

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63918/fhr.v2.n1.p30-36.2025

Abstract

Background: Tuberculosis (TB) remains a major public health challenge, particularly among children in low- and middle-income countries. Adherence to anti-tuberculosis (anti-TB) medication is essential for treatment success, but socioeconomic factors and healthcare support significantly influence adherence rates. This study examines the association between socioeconomic status (SES), healthcare support, and medication adherence among pediatric TB patients in Solok, West Sumatera, Indonesia.  Methods: A cross-sectional study was conducted involving 57 pediatric TB patients. Data on SES, healthcare support, and medication adherence were collected through structured caregiver interviews and medical record reviews. Statistical analysis included Chi-square to identify factors influencing adherence. Results: The study found that 73.7% of pediatric TB patients were adherent, while 26.3% were non-adherent. Children from higher SES backgrounds were 3.5 times more likely to adhere to treatment (OR = 3.5; 95% CI: 1.8–6.8, p = 0.003). Additionally, those receiving better healthcare support were 2.8 times more likely to adhere (OR = 2.8; 95% CI: 1.5–5.2, p = 0.041).  Conclusion: Socioeconomic status and healthcare support significantly impact anti-TB medication adherence among pediatric patients. Strengthening health policies, financial support, and community-based healthcare programs can improve adherence rates and treatment outcomes. Public health strategies should focus on targeted interventions for low-income families to reduce treatment default rates. 
The Impact of SIMCAR LASTRI Development on Team Communication in the Implementation of the Nursing Career Ladder at RSUD Tanjungpinang Asmeriyanty, Asmeriyanty; Arif, Yulastri; Putri, Zifriyanti Minanda; Dorisnita
Frontiers on Healthcare Research Vol. 2 No. 1 (2025)
Publisher : Rumah Sakit Umum Pusat (RSUP) Dr. M. Djamil

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63918/fhr.v2.n1.p77-83.2025

Abstract

Background: The implementation of a career ladder system in hospitals is crucial for the professional development of nurses. However, communication barriers within nursing teams often hinder the effectiveness of this system. SIMCAR LASTRI was developed to enhance communication within nursing teams, ensuring a more structured and efficient career progression process. This study aims to analyze the impact of SIMCAR LASTRI on team communication in the implementation of the nursing career ladder at RSUD Tanjungpinang. Methods: This study employed a quantitative analytical approach with a quasi-experimental design, involving 76 nursing practitioners at RSUD Tanjungpinang. Data were collected using structured questionnaires and analyzed using the Wilcoxon signed-rank test to assess the impact of SIMCAR LASTRI on team communication in career ladder implementation. Results: The univariate analysis revealed that the majority of respondents were female (92.1%), aged 26-35 years (73.7%), with a vocational education background (84.2%) and 7-15 years of work experience (54%). Before the implementation of SIMCAR LASTRI, 43.4% of nurses were at the Pre-PK level, and 61.84% of respondents perceived career ladder implementation as suboptimal, with major obstacles in the credentialing process (50%), competency assessment (36.84%), and issuance of Clinical Assignment Letters (SPK) and Clinical Authority Details (RKK) (34.21%). The analysis showed that before SIMCAR LASTRI implementation, the mean team communication score was 34.09 (median 34.00, range 30-37), which significantly increased to 41.88 (median 42.00, range 39-42) after implementation. Bivariate analysis confirmed a statistically significant positive impact of SIMCAR LASTRI on team communication, with a p-value of 0.000, indicating that its implementation facilitated better coordination, improved information flow, and enhanced clarity in career progression for nurses. Conclusion: These findings suggest that SIMCAR LASTRI plays a crucial role in improving communication within nursing teams, thereby optimizing the implementation of the career ladder system in hospitals. Further research is recommended to explore its long-term effects on job satisfaction, professional development, and healthcare service quality.
Evaluating the Diagnostic Accuracy of Fine Needle Aspiration Cytology in Anaplastic Thyroid Carcinoma: A Case Report and Literature Review Oktavia, Ria; Musyarifah , Zulda
Frontiers on Healthcare Research Vol. 2 No. 1 (2025)
Publisher : Rumah Sakit Umum Pusat (RSUP) Dr. M. Djamil

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63918/fhr.v2.n1.p1-8.2025

Abstract

Background: Anaplastic thyroid carcinoma (ATC) is a rare and the most aggressive malignancies originating from the thyroid gland, characterized by rapid progression, local invasion, and a poor prognosis. Timely and accurate diagnosis of ATC is crucial for guiding appropriate management strategies and improving patient outcomes. Fine needle aspiration cytology (FNAC) is useful as a rapid  initial diagnostic tool for evaluating thyroid nodules and guiding subsequent clinical management. Methods: This case series aims to evaluate the diagnostic accuracy and correlation between FNAC and histopathological examination in cases of ATC. The study focuses on three patients, who were diagnosed with ATC from FNAC, followed by surgical resection with histopathological analysis. Results: . The patients, one male (44 years old) and two females (45 and 47 years old), exhibited cytological findings in Bethesda VI, malignant categories consistent with ATC. The histopathological examination revealed the tumor was Anaplastic Thyroid Carcinoma. Conclusion: This study demonstrates FNAC's have a consistent findings with histopathology in three patients. These serial cases showed that FNAC still valuable for initial diagnosis because exhibited consistent cytological and histopathological findings for diagnosis tool. A multimodal approach, clinical judgment and imaging, is recommended to enhance diagnostic precision.
Effect of Papaya Seed on Mortality and Midgut Histopathology in Aedes aegypti Larvaes Agustini, Cynthia; Hasmiwati, Hasmiwati; Afriwardi
Frontiers on Healthcare Research Vol. 2 No. 2 (2025)
Publisher : Rumah Sakit Umum Pusat (RSUP) Dr. M. Djamil

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63918/fhr.v2.n2.p66-75.2025

Abstract

Background: Indonesia is an endemic region for Dengue infection. The World Health Organization (WHO) reported Dengue as one of the top ten global health threats in 2020. Dengue is a viral infection transmitted primarily by the Aedes aegypti mosquito, causing Dengue Fever and Dengue Hemorrhagic Fever. Temephos 1.25% has been the WHO recommended standard larvicide. However, prolonged use and continuously increasing doses may result in resistance and toxicity, posing risks to the environment and human health. This necessitates the discovery of alternative larvicides that are effective in killing larvae with minimal side effects, particularly those derived from natural materials. Methods: This research intends to illustrate the impact of papaya seed extract on the death rate of larvae and the histopathological changes in the midgut of Ae. aegypti larvae. A genuine experimental framework featuring a control group with only post-testing was utilized for this investigation. The sample comprised 750 Ae. aegypti larvae, which were categorized into six groups: one negative control group (aquades), one positive control group (temephos 1. 25%), and four treatment groups using papaya seed extract at varying concentrations of 2 mg/ml (P1), 2. 5 mg/ml (P2), 3 mg/ml (P3), and 3. 5 mg/ml (P4). Results: The results showed that all larvaes died within 24 hours in the positive control, P1, P2, P3, and P4 groups. Probit analysis of papaya seed extract revealed LC50 at 2.599 mg/ml and LC90 at 4.776 mg/ml after 8 hours of exposure. Conclusion: This study concludes that papaya seed extract affects larval mortality and midgut histopathology alterations in Ae.aegypti larvae. These findings indicate that papaya seed extract holds great potential as a natural and environmentally safe as alternative larvicide to disrupt the development of dengue fever vectors.
Comparison of Rockall and Glasgow-Blatchford Scores in GI Bleeding Boğa, Erkan
Frontiers on Healthcare Research Vol. 2 No. 2 (2025)
Publisher : Rumah Sakit Umum Pusat (RSUP) Dr. M. Djamil

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63918/fhr.v2.n2.p1-9.2025

Abstract

Background: This study aimed to compare the clinical effectiveness of the Rockall score and the Glasgow-Blatchford Score (GBS) in patients presenting to the emergency department with suspected gastrointestinal bleeding. Methods: A retrospective cross-sectional study was conducted on 350 patients admitted to Esenyurt Necmi Kadıoğlu State Hospital between January 1, 2023, and December 31, 2024, with complete clinical data. The study evaluated the predictive performance of both scoring systems regarding 30-day mortality, rebleeding, need for blood transfusion, and intensive care unit (ICU) admission. Results: The GBS demonstrated superior performance over the Rockall score in early risk assessment and in guiding hospital admission or discharge decisions. Conversely, the Rockall score was more effective in predicting long-term prognosis and the risk of rebleeding. According to ROC analysis, GBS (AUC: 0.83) outperformed the Rockall score (AUC: 0.78) in predicting mortality. Subgroup analysis indicated that the predictive value of the Rockall score declined in patients on anticoagulant therapy, while both scores showed increased predictive accuracy in patients aged ≥65 years. Conclusion: The findings suggest that the GBS is more suitable for early clinical decision-making in the emergency setting, whereas the Rockall score should be considered for long-term risk evaluation in patients with gastrointestinal bleeding.
Coexistence of Infective Endocarditis and Recurrent Acute Rheumatic Fever: A Case Report Kino, Kino; Hariyanto, Didik; Fernando, Harben; Fahlevi, Indra
Frontiers on Healthcare Research Vol. 2 No. 2 (2025)
Publisher : Rumah Sakit Umum Pusat (RSUP) Dr. M. Djamil

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63918/fhr.v2.n2.p29-34.2025

Abstract

Background: Infective endocarditis (IE) and recurrent acute rheumatic fever (ARF) are two serious cardiovascular conditions frequently associated with rheumatic heart disease (RHD). Their coexistence complicates diagnosis and management due to overlapping clinical features such as fever, migratory arthritis, and valvular dysfunction. This case report aims to elucidate the clinical presentation, diagnostic challenges, and treatment strategies in a pediatric patient with coexisting IE and recurrent ARF.   Methods: A detailed clinical case study was conducted involving a 10-year-old boy with a history of RHD presenting with joint pain and intermittent fever. Diagnostic evaluations included physical examination, laboratory investigations (including blood cultures and antistreptolysin O titers), and serial transthoracic echocardiography. Therapeutic interventions combined targeted intravenous antibiotics, corticosteroids, and secondary prophylaxis with benzathine penicillin G. Multidisciplinary consultations were employed to optimize management. Results: The patient exhibited echocardiographic evidence of mitral valve vegetations along with severe mitral regurgitation. Blood cultures remained negative, likely due to prior antibiotic exposure. Elevated antistreptolysin O titers confirmed recent streptococcal infection supporting recurrent ARF diagnosis. Clinical improvement was observed with symptom resolution and reduction in vegetation size on follow-up echocardiography. Multimodal therapy was well-tolerated, preventing further complications. Conclusion: This case highlights the diagnostic complexity and therapeutic balancing act required in managing coexisting IE and recurrent ARF in children with RHD. Early recognition through comprehensive evaluation and integrated treatment combining antimicrobial and immunomodulatory approaches can improve outcomes. Continued vigilance and multidisciplinary care are essential for preventing morbidity in this high-risk population.
Single denture as a treatment for a patient with TMD: a case report Andi, Adytha Mutiah; Arsista, Dede; Aprianto, Dharma Satya; Priambodo, Agung
Frontiers on Healthcare Research Vol. 2 No. 2 (2025)
Publisher : Rumah Sakit Umum Pusat (RSUP) Dr. M. Djamil

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63918/fhr.v2.n2.p76-81.2025

Abstract

Background: Temporomandibular joint disorder is a chronic pain caused by various factors including trauma, occlusal condition, and stress. This case report will explain about TMD case in prosthodontic which is treated with a single denture. Methods: A 50-year-old woman came to the dental clinic with aches and pains in the jaw and muscles around the head and neck. She has been using a removable denture since two months ago, but she feels uncomfortable with it. We made a new denture with an appropriate vertical dimension for the patient, with the tooth arrangement as close to the compensating curves as possible. We also trained her to do some exercises for the head and neck muscle. Results: After wearing the new denture and doing a series of muscle therapy, the patient begins to feel that the aches and pains are starting to decrease. She can more easily open and close her mouth and her lower jaw no longer feels so vibrating. Conclusion: Based on the results of clinical and subjective examinations, apart from tooth loss, all the conditions experienced by the patient also seem to be related to emotional stress due to the problems encountered.
Incidence and Risk Factors of Stroke-Associated Pneumonia in Ischemic Stroke with Dysphagia: A Cross-Sectional Study Sukiandra, Riki; Maryanti, Yossi; Sucipto; Juananda, Desby; Trihardi, Rizfan; Risman, Salsa Wiratama; Qadriyyah, Lu’lu’ul; Ashiddiqi, Hafil
Frontiers on Healthcare Research Vol. 2 No. 2 (2025)
Publisher : Rumah Sakit Umum Pusat (RSUP) Dr. M. Djamil

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63918/fhr.v2.n2.p51-57.2025

Abstract

Background: Stroke-associated pneumonia (SAP) is a common and debilitating complication following stroke, typically occurring within the first 7 days of onset in about one-third of patients with acute ischemic stroke. SAP significantly contributes to increased morbidity, mortality, and healthcare costs due to prolonged hospitalizations. In Riau, the reported prevalence of stroke is 8.3%, which has been rising since 2013, alongside an increase in SAP cases. Dysphagia, defined as difficulty swallowing, is a major risk factor for SAP as it predisposes patients to aspiration, a leading cause of pneumonia. If left untreated, dysphagia can lead to dehydration and electrolyte imbalance. Despite the clinical importance of SAP, local data regarding its incidence and associated risk factors at Arifin Achmad General Hospital in Riau Province is lacking. This study aims to investigate the incidence and risk factors associated with SAP in ischemic stroke patients with dysphagia. The findings are expected to provide evidence-based references to improve neurointensive care and preventive strategies for SAP in this patient population. Methods: This cross-sectional study was conducted at Arifin Achmad General Hospital, Riau Province, from August to November 2023. Ischemic stroke patients who underwent the Water Swallow Test (WST) were included. Dysphagia, electrolyte imbalance, and SAP were the key variables. Data were collected from medical records and observation sheets. Statistical analysis was performed using the Chi-square test (p < 0.05) with SPSS version 25. Results: The study found that 37.5% (15 patients) of ischemic stroke patients developed stroke-associated pneumonia, while 42.5% experienced dysphagia. The majority of these patients were aged 51-60 years (41.2%), male (58.8%), had their first stroke attack (60%), and had multiple risk factors (73.3%). A significant number of dysphagia patients had low electrolyte levels. The most common lesion locations in dysphagia patients were bilateral (66.7%). There was a significant correlation between dysphagia and the incidence of SAP (p=0.000). Patients with dysphagia had 78.75 times higher odds of developing SAP (95% CI: 9.95-622.6) compared to those without dysphagia. Conclusion: SAP is a frequent complication in ischemic stroke patients. Future prospective studies should adopt a unified definition, strict inclusion criteria, and long-term follow-up to better identify the incidence, prognosis, and related factors of SAP.
Weighted Scoring Design for ART Healthcare Centre Devarakonda, Shiva; Vaghela, Arjunsinh; Chudasama, Jalpaba
Frontiers on Healthcare Research Vol. 2 No. 2 (2025)
Publisher : Rumah Sakit Umum Pusat (RSUP) Dr. M. Djamil

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63918/fhr.v2.n2.p18-28.2025

Abstract

Background: Antiretroviral Therapy (ART) centers are critical in providing medical, psychological, and social support to People Living with HIV (PLHIV), as per the National AIDS Control Organization (NACO) guidelines. However, many ART centers in India face infrastructural inefficiencies, including overcrowding, poor ventilation, inadequate sanitation, and non-compliance with updated regulations. The existing layout of a long-operational ART center, established in 2008, has demonstrated such inefficiencies, necessitating a strategic redesign to optimize operational flow and improve patient outcomes. Methods: This study employed a weighted scoring system to evaluate and compare three proposed layout alternatives against the existing design. The methodology included activity flowchart mapping, space utilization studies, stakeholder input, and multi-criteria decision analysis. Twelve design evaluation criteria were prioritized using weighted scores, including feasibility (11%), patient safety (10.5%), workflow efficiency (10%), and objective adherence (13%). Designs were assessed for spatial efficiency, safety, robustness, usability, and environmental impact. Results: Design 3 achieved the highest weighted score of 6.91, outperforming Design 2 (6.865), Design 1 (5.645), and the original layout (5.275). The optimal layout improved patient flow, integrated dedicated counseling areas, enhanced staff workspaces, and improved sanitation and ventilation. Correlation analyses highlighted critical interdependencies and trade-offs among feasibility, safety, and cost factors. Design 3 also demonstrated a 30–40% reduction in congestion, compliance with NACO standards, and enhanced operational efficiency. Conclusion: The weighted scoring methodology effectively identified the optimal ART center layout. Design 3 significantly improved spatial organization, privacy, hygiene, and workflow. Future work could incorporate IoT-based monitoring and AI-driven real-time optimization for adaptive facility management. This model can be extended to other healthcare infrastructure redesigns to enhance quality and compliance.
Comparing Postoperative Fentanyl Use: Ibuprofen VS Ibuprofen-Dexamethasone as Preemptive Analgesia Herman, Awanda; Hidayat, Nopian; Sukiandra, Riki; Johannas
Frontiers on Healthcare Research Vol. 2 No. 2 (2025)
Publisher : Rumah Sakit Umum Pusat (RSUP) Dr. M. Djamil

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63918/fhr.v2.n2.p45-50.2025

Abstract

Background: Fentanyl is the most frequently used opioid analgesic for managing postoperative pain. While effective, it is associated with various side effects. Postoperative pain is mainly due to acute tissue damage. Several studies have shown that administering preemptive analgesia before anesthesia can help reduce postoperative pain, thus decreasing the need for fentanyl and its side effects. Methods: This research employed a randomized controlled trial (RCT) with a double-blind design. Postoperative pain was measured using the Numeric Rating Scale (NRS). Patients with an NRS score above 6 received fentanyl. Statistical analysis was conducted to compare the impact of preemptive analgesia with Ibuprofen 800 mg alone versus Ibuprofen 800 mg combined with Dexamethasone 10 mg in patients undergoing postoperative gynecological abdominal surgery. Results: The findings revealed a significant difference in NRS pain scores between the groups. The group receiving the combination of Ibuprofen 800 mg and Dexamethasone 10 mg had a 69% reduction in the need for postoperative fentanyl compared to the group that received only Ibuprofen. Conclusion: Patients who received preemptive analgesia with Ibuprofen and Dexamethasone had lower pain scores and a reduced need for fentanyl in the postoperative period compared to those receiving Ibuprofen alone.