cover
Contact Name
livana ph
Contact Email
livana.ph@gmail.com
Phone
+6289667888978
Journal Mail Official
livana.ph@gmail.com
Editorial Address
Jln Laut 31 Ngilir
Location
Kab. kendal,
Jawa tengah
INDONESIA
Indonesian Journal of Global Health Research
ISSN : 27149749     EISSN : 27151972     DOI : https://doi.org/10.37287/ijghr
Core Subject :
Indonesian Journal of Global Health Research is a open access, peer reviewed and refereed international journal. Indonesian Journal of Global Health Research aim to publish original research paper devoted to various area of all health sciences. Indonesian Journal of Global Health Research provides a forum for sharing timely and up-to-date publication of scientific research, health care and promoting the development of nursing, public health, community, environmental and occupational health. The journal publishes original research papers of health sciences. High priority will be given to articles on public, nursing, adolescent, community, environmental and occupational health, pharmaceutical technology, social pharmacy, traditional medicine, pharmacology, and so on.
Arjuna Subject : -
Articles 1,005 Documents
Chronic Bullous Disease of Childhood in A Resource-Limited Setting: A Diagnostic Challenge Jeniffer Handiokho; Prima Kartika Esti
Indonesian Journal of Global Health Research Vol. 8 No. 6 (2026): Indonesian Journal of Global Health Research: December 2026
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i6.2502

Abstract

Chronic Bullous Disease of Childhood (CBDC) is a rare autoimmune blistering disease that predominantly affects young children. Its diagnosis is often challenging because of clinical overlap with infectious and other autoimmune blistering disorders, particularly in resource-limited settings where direct immunofluorescence (DIF), the diagnostic gold standard, is unavailable. Objective: To describe the diagnostic approach and management of a pediatric patient with CBDC using clinicopathological correlation and systematic exclusion of differential diagnoses in the absence of DIF. This case report was based on comprehensive history taking, physical examination, medical record review, laboratory investigations, histopathological examination, treatment evaluation, and clinical follow-up of a 4 year old girl presenting with generalized blistering lesions. The clinical and laboratory findings were analyzed descriptively through clinicopathological correlation, systematic comparison with relevant differential diagnoses, and assessment of the patient's clinical response to therapy. The patient presented with a one-month history of generalized tense bullae involving the forehead and extremities, with some lesions demonstrating the characteristic cluster of jewels pattern. Histopathological examination revealed subepidermal and intraepidermal blister formation with neutrophilic and eosinophilic inflammatory infiltrates. Although DIF could not be performed because of limited institutional resources, the diagnosis was established through clinicopathological correlation, systematic exclusion of differential diagnoses, and a favorable response to dapsone therapy. Marked clinical improvement was observed within two weeks after dapsone. A structured clinicopathological approach, combined with careful exclusion of differential diagnoses and therapeutic response, can facilitate timely diagnosis and appropriate management of CBDC in resource-constrained settings where immunopathological confirmation is unavailable.
Global Research Trends on Digital Applications for Reducing Family Anxiety in Operating Room Waiting Areas: A Bibliometric Analysis Sugiono Sugiono; Wastu Adi Mulyono
Indonesian Journal of Global Health Research Vol. 8 No. 5 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i5.2514

Abstract

Family members waiting during surgical procedures often experience anxiety due to uncertainty and limited access to information. The rapid development of digital health technologies provides opportunities to support family-centered perioperative care, yet the global research landscape on this topic remains unclear. This study aimed to map global research trends, identify major research themes, and explore research gaps related to digital applications for reducing family anxiety in operating room waiting areas. A bibliometric analysis was conducted using publications retrieved from PubMed, Crossref, and Google Scholar published between January and June 2026. A total of 752 records were identified, comprising PubMed (n = 199 results), Crossref (n = 412 results), and Google Scholar (n = 141results). After duplicate removal and screening according to the PRISMA 2020 guidelines, 8 publications were included in the final bibliometric analysis. The selected records were analyzed using VOSviewer version 1.6.20 to examine keyword co-occurrence, network visualization, overlay visualization, density visualization, as well as the most productive authors and contributing countries. The analysis identified four major research clusters, including perioperative and operating room management, mental health and family well-being, evidence-based interventions, and perception and qualitative experience. Overlay visualization revealed a shift in research trends from technical operating room management toward mental health and family-centered care. Density visualization showed that studies remain concentrated on perioperative services and patient care, whereas digital applications for family anxiety reduction are still limited. The most productive authors and contributing countries demonstrate strong multidisciplinary and international collaboration, although research specifically focusing on digital interventions for family anxiety remains scarce. Research on digital applications for reducing family anxiety in operating room waiting areas is still emerging. The integration of digital health, family-centered perioperative care, and psychological support represents an important research gap and offers significant opportunities for future innovation. Developing digital applications to provide education, communication, and emotional support for families may contribute to improving perioperative healthcare services.
Efficacy and Safety of Anifrolumab in Patients with Cutaneous Lupus Erythematosus: A Systematic Review Gede Yoga Utama Putra; Anak Agung Ari Agung Kayika Silayukti; Tjokorda Istri Amrita Rosvanti; Anak Agung Istri Saraswati Dewi; Made Hemina Laksmi
Indonesian Journal of Global Health Research Vol. 8 No. 5 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i5.2515

Abstract

Cutaneous lupus erythematosus (CLE) significantly impacts patient quality of life, and many cases remain refractory to standard-of-care treatments such as antimalarials and corticosteroids. Anifrolumab, a type I interferon receptor antagonist, has shown efficacy in systemic lupus erythematosus (SLE), but its specific impact on diverse CLE subtypes in real-world settings requires further synthesis. To systematically review the clinical efficacy, safety, and steroid-sparing potential of anifrolumab in patients with CLE. A systematic literature search was conducted across PubMed, ScienceDirect, and Cochrane Library for articles published between 2021 and 2026. From an initial yield of 217 articles, 5 studies reporting on anifrolumab treatment for CLE subtypes were ultimately included after rigorous screening. Data on clinical response, specifically the cutaneous lupus erythematosus disease area and severity index (CLASI) scores and onset of action, were extracted and synthesized. Five studies involving a total of 40 patients were included. The majority of patients had failed multiple prior therapies. Results consistently showed a rapid and significant decrease in CLASI activity scores, often within the first 4 to 12 weeks of aniflorumab treatment. Notably, one major cohort reported that 50% of patients were able to discontinue prednisone entirely. Efficacy was observed across various subtypes, including discoid lupus erythematosus (DLE) and subacute CLE (SCLE) cases. Adverse events were consistent with previously reported safety profiles. Real-world evidence suggests that anifrolumab is a potent and rapid-acting treatment for refractory CLE, offering significant clinical improvement and a vital steroid-sparing effect. These findings support its use in patients failing conventional therapies, though large-scale prospective trials specifically for CLE are warranted.
Topical Hexylresorcinol, Alpha-Arbutin, and Tranexamic Acid for Melasma: A Systematic Review and Evidence Map of Efficacy, Safety, and Mechanisms Aulia Lukito Wardhani
Indonesian Journal of Global Health Research Vol. 8 No. 5 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i5.2519

Abstract

Melasma is a chronic, relapsing facial hypermelanosis sustained by photic exposure, melanocyte hyperactivity, inflammation, oxidative stress, vascular signaling, and dermal remodeling. Interest in non-hydroquinone therapies has increased because irritation and recurrence often limit long-term care. Objective to systematically evaluate the efficacy, safety, formulation characteristics, and mechanistic PubMed/MEDLINE, Scopus, Web of Science, Embase, CENTRAL, ScienceDirect, ClinicalTrials.gov, and WHO ICTRP were searched from database inception to 19 July 2026. The included studies were published between 2012 and 2025. The search identified 455 records; after duplicate removal and screening, 35 full-text reports were assessed for eligibility and 12 studies were included in the qualitative synthesis. Randomized and non-randomized clinical studies evaluating the eligible active ingredients as monotherapy or interpretable combinations were included. Risk of bias was assessed using RoB 2, ROBINS-I, or Joanna Briggs Institute tools, and certainty of evidence was evaluated using GRADE. Clinical and formulation heterogeneity precluded meta-analysis; therefore, structured narrative synthesis and evidence mapping were performed. Twelve studies met the eligibility criteria and were included in the qualitative synthesis. Seven evaluated topical tranexamic acid, three assessed alpha-arbutin-containing interventions, and two investigated hexylresorcinol-containing formulations. Nine studies directly enrolled patients with clinically diagnosed melasma, one included a mixed population of women with melasma or facial dark spots, and two provided indirect evidence from general facial or body hyperpigmentation. Topical tranexamic acid, generally administered at concentrations of 3–5% for 8–12 weeks, showed the most consistent reductions in MASI or mMASI and frequently produced short-term responses that were not significantly different from those obtained with hydroquinone, while generally causing fewer local irritant reactions. Alpha-arbutin-containing regimens improved pigmentation, but most involved co-active ingredients or enhanced-delivery systems. Hexylresorcinol reduced pigmentation in randomized dyspigmentation studies, although melasma-specific evidence remained limited. No factorial trial demonstrated clinical synergy among the three agents. Topical tranexamic acid has the strongest, although low-certainty, evidence. Alpha-arbutin and hexylresorcinol are promising, but ingredient-specific efficacy, durability, and synergy remain unconfirmed.
Analysis of Factors Associated with Patient Satisfaction among Patients with Hypertension Sahyana Sahyana; Sutrisno Sutrisno; Surmiasih Surmiasih; Riska Hediya Putri; Feri Kameliawati
Indonesian Journal of Global Health Research Vol. 8 No. 5 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i5.2529

Abstract

Hypertension is a major non-communicable disease requiring long-term management and continuous healthcare services. Patient satisfaction is an important indicator of healthcare service quality, yet evidence regarding multiple service-related factors among patients with hypertension remains limited. This study aimed to analyze the factors associated with patient satisfaction among patients with hypertension at Batin Mangunang Regional General Hospital, Tanggamus. This quantitative study employed an observational analytic design with a cross-sectional approach. The study was conducted from January to March 2026 and included 131 patients with hypertension selected using accidental sampling. Data were collected using a validated and reliable structured questionnaire and analyzed using univariate analysis, the Chi-square test, and multiple logistic regression. Overall, 54.2% of respondents reported being satisfied with the healthcare services received. Bivariate analysis showed that waiting time, medication availability, healthcare professionals’ competence, and information provision were significantly associated with patient satisfaction (p<0.05). In the multivariable analysis, all four variables remained significantly associated with patient satisfaction: waiting time (p=0.015; OR=2.558; 95% CI: 1.199–5.435), medication availability (p=0.026; OR=2.353; 95% CI: 1.105–5.000), healthcare professionals’ competence (p=0.030; OR=2.841; 95% CI: 1.107–7.299), and information provision (p=0.021; OR=2.141; 95% CI: 1.121–4.082). Healthcare professionals’ competence had the largest odds ratio in the final model. Patient satisfaction among patients with hypertension was associated with multiple dimensions of healthcare service quality. Improving healthcare professionals’ competence, reducing waiting time, ensuring medication availability, and strengthening information provision are important strategies for enhancing patient satisfaction and supporting patient-centered hypertension care.
Recurrent Ischemic Stroke in A Young Woman with Non-Adherence to Secondary Prevention: A Case Report Aeni Fikriya; Eka Afrima Sari; Hesti Platini
Indonesian Journal of Global Health Research Vol. 8 No. 5 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i5.2539

Abstract

Recurrent ischemic stroke at a young age is a relatively rare condition but carries a high risk of long-term disability. This case report aimed to describe the clinical presentation, management, and outcomes of recurrent ischemic stroke in a young woman with non-adherence to secondary prevention. A case report approach was used to describe the patient's clinical condition, assessment, interventions, and outcomes during hospitalization. Clinical data were obtained from direct patient assessment, medical records, and observations throughout the five-day hospitalization. A 27-year-old woman with a third episode of recurrent ischemic stroke presented with left hemiparesis after discontinuing treatment and routine follow-up for seven months. Neurological examination revealed muscle strength of 3/5 in the left upper and lower extremities, with paresthesia and headache. Her blood pressure on admission was 146/105 mmHg. A head CT scan demonstrated an acute ischemic infarction in the right basal ganglia. The assessment identified non-adherence to secondary prevention as a contributing factor to stroke recurrence. Management focused on stabilizing the acute phase and providing comprehensive secondary prevention education to the patient and family. After five days of treatment, muscle strength improved from 3/5 to 4/5, headache decreased, blood pressure decreased to 130/86 mmHg, and active range of motion in the left extremities improved. The patient and family also demonstrated improved understanding of and commitment to secondary prevention following discharge. This case underscores the importance of structured education, family involvement, and discharge planning in supporting adherence to secondary prevention and reducing the risk of recurrent ischemic stroke.  
Empowering Children to Assess Their Nutritional Status: The Effectiveness of A Nutrition Education Module Firnaliza Rizona; Nurna Ningsih; Zesi Aprillia; Romy Suwahyu
Indonesian Journal of Global Health Research Vol. 8 No. 5 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i5.2546

Abstract

Various forms of malnutrition occur among school-aged children, including undernutrition, overnutrition, and micronutrient deficiencies. Assessing nutritional status is essential to identify appropriate strategies for preventing more severe nutritional problems. However, many children do not know how to detect their nutritional status early, one of which can be done through anthropometric measurements. This study aimed to determine the effect of the Nergizi Module on improving students’ skills in measuring nutritional status. Method: This study employed a pre-experimental design using a one-group pretest–posttest approach. Respondents were selected through purposive sampling, involving 60 elementary school students in Palembang City, South Sumatra. The intervention was conducted three times through educational sessions using the Nergizi Module developed by the research team. Data were collected by assessing students’ skills in determining nutritional status before and after the intervention using an observation checklist. Univariate analysis was used to describe respondent characteristics, and bivariate analysis was performed using McNemar test. The results showed an improvement in students’ skills after the intervention, where initially only 12 students were categorized as having good skills, increasing to 46 students after the intervention, with a p-value of 0.001 using McNemar test. Health education using educational modules can improve students’ skills in assessing nutritional status through anthropometric measurements. The findings of this study are expected to enhance students’ ability to identify their nutritional status, thereby helping to prevent nutritional problems.
Comparison of Clinical Characteristics and Cardiac Parameters in Children with Heart Failure Due to Congenital and Acquired Heart Disease Kadir Gani; Tina Christina Lumban Tobing; Sri Sofyani; Juliandi Harahap; Tiangsa Sembiring; Cynthea Prima Destarian
Indonesian Journal of Global Health Research Vol. 8 No. 6 (2026): Indonesian Journal of Global Health Research: December 2026
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i6.2549

Abstract

Heart failure in children is a serious clinical syndrome caused by congenital heart disease (CHD) and acquired heart disease (AHD). Differences in clinical profiles and cardiac parameters between these two etiologies are important for accurate diagnosis and appropriate management. The primary objective of this study was to compare the clinical characteristics and cardiac parameters in children with heart failure due to congenital heart disease (CHD) and acquired heart disease (AHD). An analytic observational retrospective cross-sectional study was conducted using medical records of 26 children with heart failure (13 CHD and 13 AHD) at H. Adam Malik General Hospital, Medan, from January to May 2026. Variables included age, sex, nutritional status, Ross classification, dominant symptoms, as well as left ventricular ejection fraction (LVEF), fractional shortening (FS), tricuspid annular plane systolic excursion (TAPSE), troponin, valvular involvement, left atrial enlargement, QRS duration, and QTc interval. Descriptive and bivariate analyses were performed according to data distribution. There were no significant differences in age, sex, and nutritional status between groups, with most patients being undernourished. The predominant symptom was dyspnea/tachypnea, and Ross classification did not differ significantly, although AHD more often presented in higher Ross classes. Median LVEF (63.1 vs 59, p=0.005) and FS (35 vs 30, p=0.007) were significantly higher in the CHD group, whereas QTc interval prolongation was more common in AHD. TAPSE, troponin, QRS duration, valvular involvement, and left atrial enlargement did not differ significantly between groups. Clinical manifestations of pediatric heart failure due to CHD and AHD are similar and insufficient to distinguish etiology, but AHD tends to be associated with more severe left ventricular systolic dysfunction.
Topical Baby Oil Therapy for Chronic Kidney Disease-Associated Pruritus During Hemodialysis Initiation: A Case Report Nadila Ramdhiani; Sri Hartati Pratiwi; Nursiswati Nursiswati
Indonesian Journal of Global Health Research Vol. 8 No. 5 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i5.2562

Abstract

Hemodialysis initiation is a critical transitional period for patients with chronic kidney disease (CKD) and is frequently accompanied by CKD-associated pruritus (CKD-aP), one of the most distressing symptoms that can impair patient comfort, sleep quality, and adaptation to long-term dialysis. This case report aimed to evaluate the application of topical baby oil therapy for reducing CKD-associated pruritus in a patient with stage V CKD undergoing hemodialysis initiation. A descriptive case study using the nursing process approach was conducted in a 36-year-old man with stage V CKD undergoing hemodialysis initiation. The intervention consisted of once-daily topical application of baby oil in the evening for eight consecutive days. Pruritus intensity was evaluated daily using the Numeric Rating Scale (NRS), while the multidimensional impact of pruritus was assessed before and after the intervention using the 5-D Itch Scale. Pruritus intensity gradually decreased, with the NRS score improving from 9 on the first day to 6 on the final day of the intervention. The total 5-D Itch Scale score also decreased from 21 to 14, indicating improvements in pruritus duration, severity, direction, disability, and distribution.
Correlation of Leukocyte Count and Degree of Thrombocytopenia with Disease Severity in Patients with Dengue Hemorrhagic Fever Hospitalized Habil Algadrie; Isti Noviani; Mohamad Luthfi
Indonesian Journal of Global Health Research Vol. 8 No. 6 (2026): Indonesian Journal of Global Health Research: December 2026
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i6.2585

Abstract

Dengue hemorrhagic fever remains a major health problem requiring appropriate clinical and hematological monitoring. Abnormal leukocyte and platelet counts are frequently observed in affected patients, but evidence regarding their correlations with disease severity remains inconsistent. To determine the correlations of leukocyte count and degree of thrombocytopenia with disease severity among patients with dengue hemorrhagic fever hospitalized at Waled Regional General Hospital in 2025. This observational analytic study used a retrospective cross-sectional design based on medical record data. A total of 204 patients were selected through consecutive sampling. Leukocyte and platelet counts were obtained from the first complete blood count at hospital admission, while disease severity was classified according to the 2009 WHO criteria. Bivariate analysis was performed using the Spearman rank correlation test.The largest age group was children aged 6–11 years, comprising 93 patients (45.6%), and most patients were male, comprising 107 patients (52.5%). Leukopenia was found in 90 patients (44.1%), moderate thrombocytopenia in 60 patients (29.4%), and dengue with warning signs in 115 patients (56.4%). No statistically significant correlation was found between leukocyte count and disease severity (r = 0.017, p = 0.809). A statistically significant weak positive correlation was found between the degree of thrombocytopenia and disease severity (r = 0.377, p < 0.001). Leukocyte count was not significantly correlated with disease severity, whereas the degree of thrombocytopenia showed a statistically significant weak positive correlation. Greater thrombocytopenia severity tended to be associated with greater disease severity.

Page 97 of 101 | Total Record : 1005