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Majalah Kedokteran Bandung
ISSN : 0126074X     EISSN : 23386223     DOI : 10.15395/mkb
Core Subject : Health,
Majalah Kedokteran Bandung (MKB)/Bandung Medical Journal publishes peer-reviewed original articles and case reports in basic medical research, clinical research, and applied medical science. This journal is published quarterly (March, June, September, and December) by Faculty of Medicine Universitas Padjadjaran. Articles are original research that needs to be disseminated and written in English. All submitted manuscripts will go through the double-blind peer review and editorial review before being granted with acceptance for publication.
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Articles 11 Documents
Search results for , issue "Vol 55, No 4 (2023)" : 11 Documents clear
Use of sEMG for Swallowing Muscles Activity Quantification in Acute Phase of Stroke Biben, Vitriana; Tanuwijaya, Andre; Wardhani, Ildzamar Haifa; Amalia, Lisda
Majalah Kedokteran Bandung Vol 55, No 4 (2023)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v55n4.3150

Abstract

Early diagnosis of dysphagia and aspiration risk is very important in minimizing the risk of various medical consequences. This study aimed to establish a scientific database for future sEMG-based dysphagia screening investigations by examining the electrical activity of swallowing muscles in acute stroke cases. A quantitative cross-sectional study was conducted on 61 stroke inpatients admitted to Dr. Hasan Sadikin General Hospital, Bandung, Indonesia, from July to November 2019. The objective of this study was to quantify electrical activities of the suprahyoid (SH) and infrahyoid (IH) muscles during swallowing. Patients participated in both dry swallowing and a 3 mL water swallowing task, with the sEMG used to measure electrical activity parameters (duration, swallowing initiation, time-to-peak, and amplitude) on both paretic and normal sides. The Wilcoxon test was used to compare the electrical activity parameters between the patients paretic and normal sides. Only amplitude showed a significant difference between the paretic and normal side (p=0.023) when performing the 3 mL water swallowing test. Other parameters did not exhibit significant differences in activity between muscle groups during both swallowing tests (p>0.05),  although varying water volumes led to distinct activities in both muscles. Despite the absence of a clear pattern in SH and IH contractions during swallowing, the result showed that the sEMG quantification method might become a promising method for screening dysphagia, complementary to FEES and VFSS. The non-invasive and cost-effective sEMG method can serve as an early screening tool for dysphagia in stroke patients. This study underscores the importance of further investigation on sEMG use, incorporating a larger sample size and diverse cohort results with various swallowing exercises (varying in volume and viscosity) to validate the use of sEMG in dysphagia screening.
Non-Metallic and Metallic Toxicant Exposures from Personal Care Products in Indonesian Male and Female Medical Students Putra, Alby Dwinanda; Syamsir, Elmatris; Yulistini, Yulistini; Khaira, Fathiyyatul; Asri, Ennesta; Ilmiawati, Cimi
Majalah Kedokteran Bandung Vol 55, No 4 (2023)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v55n4.3254

Abstract

Students can gain various benefits from their daily personal care products. However, the chemicals contained in these products may have adverse health effects. Regardless the inspection performed by regulatory agencies on these products, the products circulating in the market may still contain toxicants thus may jeopardize their safety for use. This study evaluated toxicant ingredients contained in personal care products used by male and female college students. This study was conducted from September to December 2022 on 23 male and 46 female college students of the Faculty of Medicine, Universitas Andalas, Indonesia. Data were collected using a 69-items validated questionnaire. Results were then presented as a distribution of products used categorized by body areas and potentially toxic metallic and non-metallic ingredients identified from their labels. Female college students used at least 10 personal care products, with a median of 19 products. Male students used at least four products and a median of eight products. Investigation on the label of skin, hair, eye, dental and oral, lips, and nail personal care products demonstrated the presence of metallic and non-metallic toxicants. Five metallic toxicants (aluminum, titanium, zinc, copper, and chromium) and 15 non-metallic toxicants (triclosan, talc, fragrance, parabens, butylated hydroxyanisole, butylated hydroxytoluene, diethanolamine, triethanolamine, butylene glycol, propylene glycol, polyethylene glycol, phthalates, benzophenone-3, acetone, and fluoride) were identified. Thus, numerous toxicants are present in marketed personal care products, and females are exposed more than males to these toxicants. Consumers need to be more critical in their choice of personal care products.
Correlation Between Physical Activity and Fitness Level Among Anesthesiology and Intensive Care Residents Firdaus, Wildan; Fuadi, Iwan; Erlangga, M. Erias
Majalah Kedokteran Bandung Vol 55, No 4 (2023)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v55n4.3007

Abstract

Anesthesiologists have a highly varied scope of work. Previous studies demonstrated that the physical activity of anesthesiologists and their residency program in the work environment does not meet the recommended standards. This study aimed to determine the relationship between physical activity and level of physical fitness among anesthesiology residents. This study was an analytical observational study with a cross-sectional design conducted on residents of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Padjadjaran, Indonesia, between January and April 2022. All anesthesiology residents were asked to fill out the International Physical Activity Questionnaire (IPAQ) and had their number of steps measured using a pedometer while the physical fitness level was assessed using the Harvard Step Test. Physical activity was assessed based on the IPAQ and pedometer. The results of IPAQ measurement showed that more subjects had low physical activity (n=44) compared to good physical activity (n=31). When measured using a pedometer, 38 subjects were classified as having low physical activity while 36 had good physical activity. Low fitness level (n=43) was associated with less physical activity on IPAQ (41 and 2)and pedometer (30 and 13). No residents had moderate or better fitness levels. Correlation analysis between physical activity and physical fitness showed a significantpositive correlation with a p-value <0.05 (Spearman Rho: 0.618). Thus,physical activity and fitness level are well-correlated among of Anesthesiology and Intensive Care residents.
Effect of Hypervirulent Strains, Antibiotic Resistance, and Host Characteristics on Mortality of Klebsiella pneumoniae Bacteremia Patients at a Tertiary Referral Hospital in Denpasar, Indonesia Adhy Candra, I Kadek Bayu; Suranadi, I Wayan; Darwinata, Agus Eka; Tarini, Ni Made Adi; Dharmika, Ida Ayu Gde Wahyudevi; Fatmawati, Ni Nengah Dwi
Majalah Kedokteran Bandung Vol 55, No 4 (2023)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v55n4.3297

Abstract

Klebsiella pneumoniae bacteremia is one of the leading causes of sepsis that has a high mortality rate. The effect of multidrug resistance and different virulence of Klebsiella pneumoniae on mortality is still controversial. This study aimed to determine the impact of hypervirulent K. pneumoniae (hvKp), MDR, and clinical characteristics on mortality of K. pneumoniae bacteremia patients. A retrospective cross-sectional study was conducted on  K.  pneumoniae bacteremia cases of patients hospitalized at Professor dr. I.G.N.G Ngoerah General Hospital from December 1, 2020, to May 31, 2021. A positive PCR of rmpA, iucA genes, and/or a positive string test was identified as hvKp. The mortality rate of 51 K. pneumoniae bacteremia patients samples (aged 0-74 years) was 72.5%, in which 9.8% (5/51) of them were hvKp and 51% of the isolates (26/51) produced the Extended Spectrum Beta Lactamase (ESBL). Furthermore, 9.8% (5/51) of the cases were carbapenem-resistant. Thus, hvKp, MDR, gender characteristics, and comorbidities do not significantly affect the mortality of K. pneumoniae bacteremia patients. Multivariate logistic regression analysis showed that sepsis (odds ratio (OR) 4.29; p=0.038) and adult age group (mean 50 years) (OR 3.75; p=0.039) are independent predictors with a significant effect on mortality of  K. pneumoniae bacteremia patients. Careful and integrated management of K. pneumoniae bacteremia patients is essential for better outcomes, especially in sepsis and elderly patients. Although hvKp prevalence is low, emerging MDR-hvKp in health facilities is a severe concern for further actions and research.
Accuracy of Kampala Trauma Score as a Predictor in Assessing the Prognostic Value of Multiple Trauma Usman, Nurhayat; Ruchimat, Tommy; Rahmawan, Andhika
Majalah Kedokteran Bandung Vol 55, No 4 (2023)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v55n4.3080

Abstract

Determining a trauma scoring system appropriate for certain conditions will help in predicting mortality and morbidity, and can determine the need for treatment in patients. Kampala Trauma Score (KTS) is a trauma scoring system that uses a decent number of assessment variables and can be used in all general groups. This study was a retrospective prognostic test conducted in Dr. Hasan Sadikin Hospital Bandung, Indonesia, from December 2021 to July 2022. Data obtained was processed using Microsoft Excel and SPSS spreadsheets. The respondents were 66 people with multiple trauma. Results showed that this study was dominated by patients with blunt trauma  (n=63, 95.45%). The mean KTS score in this study was 13.08±1.03. In 49 (74.24%) patients who survived, the mean KTS score was 13.41±0.89 and in 17 (25.76%) patients who died, the mean KTS score was 12.12±0.79. The greatest mortality accuracy was at the cutoff point of the KTS score >12 (81.82% accuracy; 70.59% sensitivity; 85.71% specificity). The accuracy value of the KTS score is in line with the ROC where the optimal KTS score is >12 (85.77%). In conclusion, the Kampala trauma score can be used as a predictor in assessing the prognostic value of multiple trauma patients with the obtained cut-point value as it has high accuracy, sensitivity, and specificity values.
Front Cover, Editorial Team, Table of Contents, and Back Cover Back, Front
Majalah Kedokteran Bandung Vol 55, No 4 (2023)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Etiology and Antifungal Sensitivity Test in Otomycosis Caused by Candida Sp Darmawan, Anton Budhi; Krisniawati, Nia; Widhi, Anriani Puspita Karunia Ning; Hestiyani, Rani Afifah Nur; Kurniawan, Dhadhang Wahyu; Darmayan, Bella Jovita
Majalah Kedokteran Bandung Vol 55, No 4 (2023)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v55n4.3337

Abstract

Otomycosis is a common fungal infection of the external auditory meatus frequently diagnosed in otolaryngology outpatient clinics. Resistance to antifungals is currently a significant concern, with intrinsic and acquired resistance increasing among isolates that cause fungal infections. The purpose of this research was to identify Candida species causing otomycosis and determine the pattern of antifungal susceptibility among these Candida species. A prospective study was conducted in the Margono Soekarjo General Hospital and Department of Microbiology, Faculty of Medicine, Universitas Jenderal Soedirman Purwokerto, Indonesia, from April – September 2022. Forty-seven (47) clinical samples of otomycosis were collected from 41 patients and then isolated bedside on fungal culture media and was prepared on an object glass for direct microscopic examination of the specimens. Fungal identification was performed using 10% potassium hydroxide (KOH) to observe fungal elements. Samples were cultured on Saboraud dextrose agar (SDA) media with chloramphenicol and Czapek dox agar. The Germ Tube Test was used to identify Candida while yeast-specific identification and antifungal susceptibility assay using a rapid commercial kit was applied for specific identification of the fungus. Antifungal susceptibility patterns were obtained using the Integral System Yeast Plus (ISYP) media pack. Candida parapsilosis was the most prevalent Candida species discovered in this study, accounting for approximately 41.66%, which was followed by Candida tropicalis (25%) and Candida krusei (12.5%), whereas Candida albicans only accounted for 4.1% of the specimens. All Candida species were sensitive to flucitosine and ketoconazole, whereas the voriconazole sensitivity rate reached 96%.  This study concludes that Candida parapsilosis is the most prevalent species of Candida in otomycosis, and that all Candida species are sensitive to Flucitosine, ketoconazole, and voriconazole.
Validity Test For C-Reactive Protein and Ferritin Level in Moderate and Severe Covid-19 Patients Kurnia, Chyntia Putriasni; Wasilah, Fajar; Lismayanti, Leni
Majalah Kedokteran Bandung Vol 55, No 4 (2023)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v55n4.3025

Abstract

Mild, moderate, severe, and critical COVID-19 are associated with hyperinflammation. The CRP and ferritin are acute phase proteins that marks incidence of inflammation and used as the paramaters of hyperinflammation. This study aimed to determine the validity of CRP and ferritin level examination in moderate and severe COVID-19 since the time of admission. This was a cross-sectional analytical retrospective study with on moderate and severe COVID-19 patients admitted to Dr. Hasan Sadikin General Hospital Bandung, Indonesia, during the period of March 2020 to December 2020. The CRP and ferritin levels were obtained since the beginning of admission to the fourth day since admission on patients without any history of anemia. Subjects in this study were divided into moderate and severe COVID-19 groups based on the 3rd edition of COVID-19 Prevention and Control Guideline issued by the Ministry of Health Republic of Indonesia. Each group consisted of 30 subjects. The cut-off value was 7.65 mg/dL (AUC 0.698) for CRP and 963.1 mcg/L (AUC 0.938) for ferritin. The validity of ferritin vs CRP were reflected respectively as follows:  93.3% vs 76.7% sensitivity; 80.0% vs 63.3% specificity; 82.4% vs 67.6% PPV; and 92.3% vs 73.1% NPV. The validity of ferritin was proven to be superior as it  significantly increases since day one, persisted longer and reaches its peak on  the16th day. Meanwhile, CRP increases within 6-8 hours and reaches its peak within 48 hours after inflammation, then declines soon afterwards.
Impact of Severe Preeclampsia on the Incidence of Low-Birth-Weight Babies Ferawati, Emi; Kuswandi, Kadar; Karmila, Nela
Majalah Kedokteran Bandung Vol 55, No 4 (2023)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v55n4.3277

Abstract

Infant birth weight is an important indicator of survival, growth potential, and developmental capacity. Maternal health plays an important role in determining the well-being of newborns. A complicated pregnancy, inclusive of conditions such as preeclampsia, elevates the risk of giving birth to a low birth weight (LBW) baby. This study aimed to compare the impact of severe preeclampsia on the incidence of LBW babies in Dr. Dradjat Prawiranegara General Hospital Serang, Indonesia. This case-control analysis included 148 parturients recruited randomly from June to October 2022. Logistic regression was used as the analytical tool, with P=0.000 considered as demonstrating a significant association. The incidence rates of LBW and severe preeclampsia in 2018 were 19.84% and 14.15%, respectively. The case group recorded LBW within the weight range of 1,000-2,450 g, with 38% of them were Small for Gestation Age (SGA), while 50% and 12% were Appropriate for Gestational Age (AGA), and Large for Gestational Age (LGA), respectively. In contrast, the control group, with birth weights ranging from 2,600-4,500 g, 13.50% were SGA, while 77% and 9.50% were AGA and LGA, respectively. Parity was a confounding factor influencing the incidence of LBW, while maternal age did not present a significant correlation. Pregnancies with severe preeclampsia were found to have a 29-fold increased likelihood of delivering LBW babies compared to the control group when controlling for parity (P=0.000, CI 95%). Hence, women with severe preeclampsia pregnancies have a higher risk for delivering LBW babies of 29 times higher than the control.
Giant Pyonephrosis Due to Calculus of Ureter: A Case Report Singgih, Nicholas Andrian; Lionardi, Stevan Kristian; Mintardi, Mintardi
Majalah Kedokteran Bandung Vol 55, No 4 (2023)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v55n4.2985

Abstract

Giant pyonephrosis (GP) is a rare and severe form of pyonephrosis characterized by a massive enlargement of the affected kidney due to the accumulation of infected fluid. This study presents case of a 51-year-old male patient with giant pyonephrosis who underwent nephrectomy as treatment. The clinical manifestations of giant pyonephrosis are nonspecific, necessitating the use of imaging and laboratory techniques to aid in diagnosis. Nephrectomy is the preferred treatment option for these patients. One week after nephrectomy, the laboratory results showed improvements. Making the right treatment decision is challenging in this particular case.

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