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INDONESIA
e-Journal Pustaka Kesehatan
Published by Universitas Jember
ISSN : 2355178X     EISSN : 27213218     DOI : -
Core Subject : Health, Science,
Health Professions Library & Information Science
e-Journal “Pustaka Kesehatan” merupakan jurnal elektronik ilmiah berISSN (ISSN: 2355-178X) yang menerbitkan artikel hasil penelitian di bidang kesehatan secara umum meliputi: Kedokteran, Kedokteran Gigi, Kesehatan Masyarakat, Farmasi, dan Ilmu Keperawatan. Artikel yang dikirim belum pernah dipublikasikan atau tidak dalam proses penerbitan dalam jurnal ilmiah lain. e-Journal “Pustaka Kesehatan” diterbitkan tiga kali dalam setahun, yaitu bulan Januari, Mei, dan September.
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Articles 621 Documents
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Efektivitas Ekstrak Etanol Daun Bayam Merah sebagai Hepatoprotektor terhadap Kadar ALP Serum Mencit yang Diinduksi Isoniazid (Hepatoprotective Activity of Red Spinach (Amaranthus tricolor L.) Leaves Ethanolic Extract on ALP Serum Mice Induced by Isoniazi Shinta Madyaning Wuri; Aris Prasetyo; Elly Nurus Sakinah
Pustaka Kesehatan Vol 5 No 3 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Isoniazid (INH) is metabolized become hidrazine that depleted glutation (GSH) in hepatocytes, resulted imbalance oxidant and antioxidant along with increased of free radicals, which can increase alkaline phosphatase (ALP). Ethanolic extract of red spinach (Amaranthus tricolor L.) leaves contains antioxidant which can donates the electron so free radical can be stabilized. The aim of this study was to investigate the effect of ethanolic extract of red spinach leaves on ALP levels of mice induced by INH and its effective dose. This research used 28 mices that divided into seven groups: K(N) was given normal saline, K(-) was given INH 100 mg/kgBW, K1, K2, K3, K4 and K5 group which given INH 100 mg/kgBW peroral and after 2 hours would be given ethanolic extract of red spinach leaves in the dose 1,05 mg/20gBW, 2,1 mg/20gBW, 4,2 mg/20gBW, 8,4 mg/20gBW and 16,8 mg/20gBW for ten days. ALP serum was measured on the day 11th.The result of average ALP levels were K(N) 41,36 U/L, K(-) 110,97 U/L, K1 79,26 U/L, K2 71,34 U/L, K3 66,51 U/L, K4 62,82 U/L and K5 47,21 U/L. In conclusion the ethanolic extract of red spinach leaves could prevent the increasing of ALP levels and the effective dose of the extract was 6,75 mg/20gBW. Keywords: red spinach leaves, ALP, INH
Penentuan Kadar Flavonoid pada Ekstrak Daun Tanaman Menggunakan Metode NIR dan Kemometrik (Determination of Flavonoid in Leave Extracts Using NIR and Chemometric) Hilmia Lukman; Lestyo Wulandari; Yuni Retnaningtyas
Pustaka Kesehatan Vol 4 No 1 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Flavonoids are a group of natural compounds with variety phenolic structures and are found in plants. The aim of this research was to study whether NIR and chemometric methods could be used to determine the flavonoid content. These methods were compared to UV-Vis spectrofotometry. Flavonoid was extracted from plant leaves by ultrasonic and maceration. NIR spectral data of selected leave extracts were correlated with flavonoid content using chemometric. In this study, the chemometric method that used for quantitative and qualitative analysis were Partial Least Square (PLS) and Linear Discriminant Analysis (LDA), respectively. The PLS R2 calibration was 0.9916499 and RMSEC was 2.1521897. In addition, the R2 of LOOCV and 2-Fold-Cross-Validation were 0.9986664 and 0.9823225, respectively. Furthermore, LDA gave accuracy of 100%. The significance of flavonoid content that have been measured by NIR and UV-Vis spectrofotometry was evaluated with paired samples t-test. In conclusion, flavonoid content that have been measured with both methods gave no significant difference. Keywords: flavonoid, chemometric, LDA, NIR, PLS
Gambaran Perkembangan Motorik Kasar pada Balita Usia 1-3 Tahun dengan Stunting di Wilayah Kerja Puskesmas Sumberjambe, Jember Nadia Farah Meidina; Lantin Sulistyorini; Peni Perdani Juliningrum
Pustaka Kesehatan Vol 7 No 3 (2019): Volume 7 No.3, 2019
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v7i3.10942

Abstract

The condition of stunting toddlers can affect the ability in aspects of gross motor development. Gross motor development of stunting toddlers is also influenced by optimal nutritional status between the balance of intake and nutritional needs. This study aims to determine the description of gross motor development in stunted infants aged 1-3 years (toddler) in Sumberjambe Health Center, Jember Regency. This study used a descriptive design with a cross sectional approach. Respondents within this study were 200 stunted toddlers with purposive sampling method. The data collection was carried out using the Denver II observation sheet. Data analysis was performed by descriptive analysis by describing data in table form. The results of gross motor development found that 144 infants (72,0%) had normal gross motor development, 43 toddlers (21,5%) had suspected, and 13 toddlers (6,5%) had abnormal gross motor development. The role of parents, family, and the environment is expected to be able to be involved and directly control the condition of toddlers by frequently interacting to determine motor skills in achieving gross motoric development that is optimal in stunted toddlers.
Pengaruh Pajanan Radiasi Sinar-X dari Radiografi Panoramik terhadap pH Saliva (The Effects of Panoramic Dental X-Ray Radiation Exposure on Salivary pH) Nungky Tias Susanti; Swasthi Prasetyarini; Amandia Dewi Permana Shita
Pustaka Kesehatan Vol 4 No 2 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Background: Panoramic radiograph is a dental radiodiagnosis which is often used to assist in establishing diagnosis and determining treatment plans using low dose x-ray radiation exposure.The basic working principle of panoramic radiograph is using ionizing radiation which causes ionization reactions on the affected objects. Radiation area in patients undergoing panoramic radiograph involves salivary glands, thus it generates certain impacts in the quality and quantity of saliva produced. Aim: To analyze the effects of panoramic dental x-ray radiation exposure on salivary pH. Research Method: This study used quasi experimental research method with pre and post test only control group design. Eight people were chosen as samples based on inclusion and exclusion criteria. Saliva testing was performed to the chosen samples pre and post panoramic dental x-ray radiation exposure. The research data were measured using paired t-test statistical analysis. Result: There wassignificant difference on salivary pH pre and post panoramic dental x-ray radiation exposure (p<0,05). Conclusion: Panoramic dental x-ray exposure can decrease salivary pH. Keywords: Panoramic radiograph, Salivary pH
Perbedaan Kualitas Hidup Lansia yang Tinggal di Komunitas dengan di Pelayanan Sosial Lanjut Usia (The Different of Quality of Life Among the Elderly who Living at Community and Social Services) Amalia Yuliati; Ni'mal Baroya; Mury Ririanty
Pustaka Kesehatan Vol 2 No 1 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Quality of life is a very board concept that was affected by individual physical condition, psychological, level of independence, and individual's relationship with the environment. This research aimed to determine differences in the quality of life of the elderly who living at community and Social Services, according to the physical, psychological, social, and environmental domain. This research was analytically studies using cross sectional design. The number of sample was 210 respondent. Mann Whitney and Kruskal Wallis test (alpha 0,05) was applied to analyze the data. There were not significant difference between quality of life of the elderly living at community and at Social Services in Jember (p=1.000). Based on domain quality of life, the were significant difference between physical, psychological, social, and environmental domain of the elderly living at community and Social Services in Jember.   Keywords: elderly people, quality of life, community, Social Services  
Uji Efektivitas Beras Herbal Forte terhadap Penurunan Kadar Glukosa Darah Pasien Diabetes Melitus Tipe 2 (Study of the Herbal Rice Forte Effectiveness on Decreasing Blood Glucose of Diabetes Mellitus Type 2 Patient) Gema Akbar Wakhidana; Ancah Caesarina Novi Marchianti; Ali Santosa
Pustaka Kesehatan Vol 6 No 1 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i1.6789

Abstract

Diabetes mellitus is metabolic diseases characterized by hyperglycemia caused by disturbances in insulin secretion or insulin activity. Herbal Forte Rice is rice synthetic material composed of main purple sweet potato and corn flour. It contains antioksidan, fiber, resistant starch and having moderate glycemic index. This study aimed to determine the effectivity of Herbal Forte Rice on decreasing blood glucose levels of patients type 2 DM. It used a cross-over design, the role of research subjects was both as control and treatment groups. Total sample of this research consisted of 60 samples. The treatment group was given Herbal Forte Rice for 7 days in 2 consecutive meals, while the control group did not receive any intervention. The results showed the average level of Fasting Blood Glucose (FBG) beginning and end of the treatment group 179.76 mg/dL and 138.7 mg/dL; FBG beginning and end of the control 180.87 mg/dL and 187.63 mg/dL; 2 hours post prandial Blood Glucose (2hppBG) levels of beginning and end of the treatment group 284.37 mg/dL and 183.8 mg/dL; 2hppBG levels beginning and end of the control 280.57 mg/dL and 284.13 mg/dL. This study concludes that Herbal Forte Rice effective on decreasing blood glucose levels of patients type 2 DM. Keywords: diabetes mellitus, Rice Herbal Forte, GDP and GD2PP
Pengalaman Kehamilan Perempuan Primigravida dengan Riwayat Menikah Usia Dini di Desa Baletbaru Kecamatan Sukowono Kabupaten (The Experience of Primigravida Pregnancy with Child Marriage in Baletbaru Village of Sukowono District) Rona Gitayanti; Lantin Sulistyorini; Ratna Sari Hardiani
Pustaka Kesehatan Vol 4 No 1 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

A Woman health which need to be understood and undertaken in line with health care services. One of health problems that a Woman often experiences is child marriage. Child marriage is one of the phenomena of Woman health problem in Jember Regency. This research purposes to obtain the experience of primigravida pregnancy with child marriage in the Baletbaru Village. The research used qualitative method, with descriptive phenomenological study design. The sampling technique used purposive sampling with the number of participants as many as 4 people. The study is identifying 8 themes: the desire, assessment of early marriage, a representation of early marriage, normal complaints, pathological complaints, general feeling, special feeling, and the health care what use for. The research results indicated that unreadiness primigravida in physically and psychologically to face child marriage and pregnancy. This research are expected to be the bases for developing policy of marriage and Woman healthcare service. Keywords : Primigravida, Child marriage, Pregnancy experience
Uji Sitotoksisitas dan Proliferasi Senyawa 1-(4-nitrobenzoiloksi- metil)-5-fluorourasil terhadap Sel Kanker Payudara MCF-7 (Cytotoxicity and Proliferation Studies of 1-(4-nitrobenzoyloxy- methyl)-5-fluorouracil) on Breast Cancer Cells MCF-7) Eka Mustika Wati; Ayik Rosita Puspaningtyas; Dian Agung Pangaribowo
Pustaka Kesehatan Vol 4 No 3 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

1-(4-nitrobenzoyloxymethyl)-5-fluorouracil (4-NFU) is a derivative of anticancer drug 5-fluorouracil (5-FU) which has been substituted by alkyl, ester, benzene, and nitro groups at N1 position. 4-NFU has been synthesized by Kurnia but anticancer study has not been reported. This research aims to compare the cytotoxicity and antiproliferative activity between 4-NFU and 5-FU on MCF-7 cells. The cytotoxicity and antiproliferative activity were studied by MTT method. The cytotoxicity study was done for 24 hours. The antiproliferative study was done for 24, 48, and 72 hours. The result showed that cytotoxicity activity of 4-NFU (IC50 = 134.039 μM) was higher than 5-FU (IC50 = 4211.508 μM) on MCF-7 cells. Based on the unpaired t test, there was a significant difference between IC50 of 4-NFU and 5-FU (α<0.05). The antiproliferative study showed that there was a growth inhibition on MCF-7 cells. The doubling time value of 4-NFU was 290.51 hours at ½ IC50; 350.97 hours at IC50; and 418.2 hours at 1½ IC50. The doubling time value of 5-FU was 185.99 hours at ½ IC50; 214 hours at IC50; and 220.63 hours at 1½ IC50. The doubling time value of 4-NFU was higher than 5-FU so that antiproliferative activity of 4-NFU was higher than 5-FU on MCF-7 cells. Keywords: 1-(4-nitrobenzoyloxymethyl)-5-fluorouracil, cytotoxicity, proliferation, MCF-7
Determinan Unmet Need KB Pada Wanita Menikah di Kecamatan Klabang Kabupaten Bondowoso (Determinants for Family Planning Among Married Women at Klabang Sub District in Bondowoso) Ratna Katulistiwa; Ni'mal Baroya; Dwi Martiana Wati
Pustaka Kesehatan Vol 2 No 2 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Unmet need for family planning is a multidimentional problem because it is influenced byvarious factors. Unmet need for family planning at East Java in 2013th was decrease from14,89% become 13,44%. But, the unmet need issue was enough higher than anotherprovince. Although, the unmet need issue in Bondowoso was high and Klabang sub districtwas higher than another distric in Bondowoso. This research aim to determine of unmetneed for family planning among married women, according to the demographiccharacteristic, social economic, and access in family planning services. This research wasanalytically, using cross sectional design. The number of samples was 219 respondentswho chosen by proportional random sampling technique. Bivariable analysis by Chi Squaretest and multivariable analysis by logistic regression (α=5%). There is a significant relationbetween the number of living children (OR=0,08), wealth status (OR=3,7), geographic orphysical accessibility (OR=0,19), psychosocial accessibility (OR=0,23), and cognitiveaccessibility (OR=3,84) with unmet need for family planning among married women.Keywords: Married women, unmet need, family planning
Prevalensi dan Distribusi Penderita Stomatitis Aftosa Rekuren (SAR) di Klinik Penyakit Mulut RSGM FKG Universitas Jember pada Tahun 2014 (Prevalence and Distribution of Patients Recurrent Aphthous Stomatitis ( RAS ) in Oral Medici Annisa Sulistian; Sri Hernawati; Ayu Mashartini P
Pustaka Kesehatan Vol 4 No 3 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Background: Recurrent Aphthous Stomatitis (RAS) is a disorder characterized by recurring ulcers confined to the oral mucosa with no other signs of disease. RAS is classified according to three classification, there are RAS minor, RAS mayor, and RAS herpetisformis. RAS prevalence of general population ranges from 5%-66%. Purpose: This study aimed to obtain the prevalence and distribution of patients suffering from RAS in Oral Medicine Departement of Dental Hospital, Dentistry Faculty, University of Jember in 2014. Method: This study used descriptive study with retrospective approach and purposive sampling. The population of this study is all patients of Oral Medicine Departement of Dental Hospital, Dentistry Faculty, University of Jember in 2014 as many as 1073 peoples. Result and Conclution: The result showed that 146 patients suffer SAR (14%) from 1037 patients in Oral Medicine Departement of Dental Hospital, Dentistry Faculty, University of Jember on January until December 2014. There were 97% of patients had RAS minor, 3% of patients had RAS mayor, and 0% of patients had RAS herpetisformis from 146 patients with RAS. RAS can occur in women or men and children or adults, the result of this research showed that RAS was most common in women, that was 70% and the age groups of 12-24 years was 54%. Keywords: Distribution, Prevalence, Recurrent Aphthous Stomatitis (RAS)

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