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Alchemy : Journal of Chemistry
Published by Universitas Islam Negeri Maulana Malik Ibrahim Malang
ISSN : 20861710     EISSN : 24606871     DOI : http://dx.doi.org/10.18860/al
Core Subject : Science, Engineering,
Chemical Engineering, Chemistry & Bioengineering Chemistry Energy Materials Science & Nanotechnology
ALCHEMY: Journal of Chemistry (eISSN 2460-6871) is a scientific journal that focus on chemistry. This journal publishes a scientific article that cover research and review articles. Research topics for this journal such as natural science, physical chemistry, inorganic chemistry, organic chemistry, environment, biochemistry, marine, energy and other related-sciences. ALCHEMY: Journal of Chemistry also accepts article about halal products and chemistry on Islamic perspectives.
Arjuna Subject : Kimia(semua kategori) - Kimia (Lain-Lain)
Articles 8 Documents
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Search results for , issue "Vol 12, No 1 (2024): ALCHEMY: JOURNAL OF CHEMISTRY" : 8 Documents clear
Pemetaan Komponen Metabolit Sekunder Utama dari Tanaman Berkhasiat terhadap Paru paru menurut Al-Qanun fi at-Tibb 2 karya Ibnu Sina djamain, nelly suryani; Nurkholiza, Zahara Faiziah; Saibi, Yardi Yardi; Betha, Ofa Suzanti; Dahlizar, Sabrina Sabrina; Dillasari, Estu Mahanani
ALCHEMY:Journal of Chemistry Vol 12, No 1 (2024): ALCHEMY: JOURNAL OF CHEMISTRY
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/al.v12i1.21469

Abstract

Al-Qanun fii at-Tibb 2 is a medical text book by Ibn Sina, which contains monographs of various natural materials, especially plants that have properties for organs including the lungs. In this book there is no data regarding the secondary metabolite content of these plants and this study aims to conduct a literature review of the main secondary metabolite components of these plants. and see the correlation between the major components and their efficacy on the lungs. This research was conducted using the literature review method through various databases by extracting from 124 scientific journals information about 58 plants that are efficacious for lung organs according to Al Qanun Fi'l Tibb and data has been produced in the form of the content of the main secondary metabolites of these plants, namely flavonoids, terpenes, tannins, lignans., saponins, anthraquinones, glucosinolates, phenolic acids, sekoiridoids, steroids, and alkaloids as the major components. Based on the results of this review, the main components of secondary metabolites are known to have reported beneficial bioactivities in the treatment of the respiratory system and lung organ.
Sediaan Gel dari Kombinasi Ekstrak Buah Gandaria (Bouea macrophylla Griff.) dan Ekstrak Belimbing Wuluh (Averhoa bilimbi L) dan Bioaktivitasnya Jayantie, Dhyneu Dwi; Khaerunnisa, Arini; Renaldy, Renaldy; Suryani, Nani; Rudiana, Tarso
ALCHEMY:Journal of Chemistry Vol 12, No 1 (2024): ALCHEMY: JOURNAL OF CHEMISTRY
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/al.v12i1.23451

Abstract

Melanin is the main pigment thfunctions to protect the skin from exposure to ultraviolet light, excessive melanin synthesis can cause skin hyperpigmentation. A. bilimbi and B. macrophylla fruits have bioactive compounds such as phenolics, flavonoids that function as antioxidants and tyrosinase inhibitors. This study aims to formulate a gel preparation of a combination of fruit extracts of A. bilimbi and B. macrophylla, test antioxidant activity using the DPPH method, and test tyrosinase inhibition enzymes. Three formulas were made, namely F0 (Basis), FI (50x extract), and FII (100x extract). Physical evaluation includes organoleptic, homogeneity, pH, adhesion, spreadability, viscosity, viscosity and irritation. Test of antioxidant activity and tyrosinase enzyme inhibition. Then the data were analyzed descriptively and statistically. The results of the evaluation of homogeneous preparations, dispersion, pH, viscosity, mandatory, meet the standards. Adhesion below standard, irritation test (mild irritation). The results of IC50 antioxidants were F0 (2,352 ppm), FI (1,448 ppm), FII (419,74 ppm) and gel brand x (77,429 ppm). The results of the tyrosinase inhibition test were the highest concentration of 10% F0 (7.828%), a concentration of 10% FI (18.245%), a concentration of 10% FII (25.814) kojic acid gel (brand x) as a comparison with a concentration of 10% (51.211%). The higher the concentration used, the greater the inhibition of the tyrosinase enzyme produced
Phytochemistry and Antibacterial Activity of the Water Extract from Paraserianthes falcataria Masruri, Masruri; Wiryawan, Adam; Ikhtiarini, Nur; Nurravida, Elvira
ALCHEMY:Journal of Chemistry Vol 12, No 1 (2024): ALCHEMY: JOURNAL OF CHEMISTRY
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/al.v12i1.24234

Abstract

Chemotaxonomic and phylogenetic studies show that sengon wood (Paraserianthes falcataria) has the potential to produce secondary metabolites with diverse structures and are bioactive. This research aims to study the chemical composition of the water extract and the bioactivity for inhibiting bacteria of Sengon (Paraserianthes falcataria). The method involves extraction by maceration, and analysis the extract by LCMS/MS methodology. In addition, the extract was evaluated to inhibit the Escherichia coli and Staphylococcus aureus. It was found that indohoki77 menggunakan teknologi enkripsi terbaru untuk memastikan bahwa data pribadi dan transaksi finansial para pemain aman dari ancaman pihak ketiga the water extract gives a viscous brown liquid, and the identified compound indicate the present of glycosidic compound, amino-alcohol structure, and fatty acid ester. Moreover, the antibacterial evaluation was able to inhibit the growth of E. coli 8.685 ± 4.876 mm, and toward the S. aureus bacteria 14.120 ± 4.418 mm, respectively.
Bioinformatics Approach: Evaluating the Antiviral Potential of Flavonoid Compounds from Phyllanthus urinaria against Foot-and-Mouth Disease in Livestock Animals Nugroho, Endik Deni; Sururi, Ahmad Misbakhus; Ardiansyah, Reza; Rahayu, Dwi Anggorowati; Ainiyah, Roisatul; Fathurrohman, Amang; Ahwan, Zainul; Dayat, Muhammad; Wibisono, Mulyono; Aji, Fatit Rahmar; Kasiman, Kasiman
ALCHEMY:Journal of Chemistry Vol 12, No 1 (2024): ALCHEMY: JOURNAL OF CHEMISTRY
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/al.v12i1.23575

Abstract

Foot-and-mouth disease is a severe problem that must be faced in the livestock sector. This disease has a negative impact on various aspects, especially the economy. One way to develop herbal medicinal compounds is through local Indonesian wild plants, meniran (Phyllanthus urinaria). This research aims to determine the potential of the wild plant P. urinaria as an antiviral agent for FMD using an in silico approach using molecular docking. The compounds used as ligands are flavonoid compounds in P. urinaria, namely, routine, quercetin 7-methyl ether, quercetin 3-O-β-D-glucoside, quercetin, rhamnocitrin, astragalin, and kaempferol. This study used the control drug ribavirin as a comparison. The research stage began with the preparation of the RdRp protein from the FMD virus with Discovery Studio, ligand preparation with the Lipinski druglikeness test and minimization using OpenBabel, followed by docking and visualization. The research results found that the six flavonoid compounds in P. urinaria have potential as antiviral FMD by inhibiting RdRp, with the most potent compound being quercetin (-7.9 kcal/mol). Further research is needed, including in vitro and in vivo testing, to provide confidence in the potential of this wild plant as an antiviral for FMD.
Synthesis of Smart Packaging from Cellulose Acetate with The Addition of AgNO3 as An Antibacterial Substance Febryanti, Amalyah; Benu, Marlon; Aferta, Lusi; Siswara, I.M; Mulijani, Sri; Alif, Alfiah
ALCHEMY:Journal of Chemistry Vol 12, No 1 (2024): ALCHEMY: JOURNAL OF CHEMISTRY
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/al.v12i1.13019

Abstract

Synthesis of smart packaging from cellulose acetate with the addition of AgNO3 as an antibacterial substance has been investigated. The purpose of this study is to fabricate smart packaging from cellulose acetate with the addition of AgNO3 as an antibacterial substance. The method used was solution casting. In addition, this study was also characterizing the smart packaging, they included tensile strength and elongation percent test, antibacterial test, morphology analysis using SEM, and biodegradability test. The plastics obtained were clearly yellow, not easily damaged, a little thick, and the smooth surface and slightly bubbly. The largest tensile strength of plastic was 0.0661 MPa, it found in sample No. 2, while the smallest tensile strength was 0.027 MPa, it found in sample No. 1. The greatest elongation value at break was 5% found in sample No. 4, while the smallest elongation value at break was 3.5% in sample No. 3. The result of antibacterial test reported that the freshest mangoes were shown by samples No. 1 and No. 2; while the fast-rotting mangoes were shown in the sample No. 3 and No. 4. The results of the SEM test showed the presence of nano-sized particles that spreaded in the plastic body. The greatest degradability degree were sample No. 4 about 0.0009 g/day with the percentage of mass loss about 17.38%. Futhermore, cellulose acetate can be used as a basic material for making plastics. The addition of AgNO3 in plastic synthesis can help to delay the process of fruit spoilage caused by bacteria.
Elemental Composition of Sand Puya Processed through Alkali Fusion with Sodium Hydroxide Zaharah, Titin Anita; Lestari, Agustina Duwan; Sembiring, Albert; Silalahi, Imelda Hotmarisi
ALCHEMY:Journal of Chemistry Vol 12, No 1 (2024): ALCHEMY: JOURNAL OF CHEMISTRY
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/al.v12i1.23017

Abstract

Puya sand is a well-known name by people in West Borneo, for remainder sand from gold mining conducted by local people, contains a mixture of minerals consist of elements, such as zirconium, silicon, iron, titanium and rare earth metals.  In order to recover and separate the minerals, an initial chemical process, i.e., alkali fusion reaction with sodium hydroxide has been conducted.  Puya sand that have been pre-treated, called magnetic sand (pasir tertarik magnet, PTM) was reacted with NaOH in various mass of PTM:NaOH 1:0.5, 1:1 and 1:2 as well as various temperature of 550 °C, 600 °C , 700 °C and 800 °C for each concentration variants. The X-ray diffraction (XRD) analysis showed that the main mineral found in PTM is zirconium silicate, ZrSiO4 which is crystalline, however it became an amorph material after it was reacted with NaOH at 550 °C. In a mass ration of PTM:NaOH of 1:2 at 550 °C, the reaction product calcinated at 800 °C appeared to form hematite, zirconia and silica shown by the XRD analysis. The analysis of X-ray fluorescence (XRF) demonstrated a different elemental composition in a different reaction condition. Zirconium silicate likely was decomposed to zirconate and silicate assigned by a high Zr/Si ratio, seen more obvious at the temperature of 700 °C, in which the highest Zr/Si ratio was found at the mass ratio of PTM:NaOH, 1:2. The fusion reaction between PTM and NaOH at 600 °C and PTM:NaOH of 1:2 resulted in a material with the highest concentration of iron element relative to other elements. Reaction undertaken at 700 °C and mass ratio of PTM:NaOH of 1:0.5 gave a product with the highest concentration of titanium elements or oxide. Depends on the mineral target aimed to decompose, the condition of alkali fusion reaction is an important aspect to take into account.
Analisis Kandungan Formalin dan Protein pada Ikan serta Uji Kesegarannya Isa, Ishak; Iyabu, Hendri; Nento, Tia Dwi Lestari
ALCHEMY:Journal of Chemistry Vol 12, No 1 (2024): ALCHEMY: JOURNAL OF CHEMISTRY
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/al.v12i1.21054

Abstract

Ikan merupakan bahan pangan yang mengandung protein tinggi yang menyebabkan terjadinya pembusukan oleh mikroorganisme. Oleh sebab itu, proses pengawetan perlu dilakukan. Salah satu bahan yang biasa digunakan yaitu formalin. Penelitian ini bertujuan untuk mengetahui keterkaitan antara protein, TVB-N dan organoleptik serta untuk mengetahui kandungan formalin dan protein pada ikan. Analisis kualitatif formalin menggunakan pereaksi Schiff serta analisis protein menggunakan metode Biuret dengan instrumen Spektrofotometer UV-Vis. Hasil analisis 8 sampel ikan menunjukkan bahwa seluruhnya negatif mengandung formalin dan kadar protein dalam ikan sebesar 15,85-32,45%. Untuk uji kesegaran ikan menggunakan TVB-N. Hasil uji TVB-N pada ikan sebesar 0,81-7,18 mgN%. Berdasarkan hasil penelitian bahwa semakin tinggi TVB ikan, protein semakin rendah dan kualitas ikan semakin rendah. Sebaliknya, semakin rendah TVB ikan, protein semakin tinggi dan kualitas ikan semakin baik.Kata Kunci: Formalin, protein, Spektrofotometer UV-Vis, TVB-N
Analisis Sidik Jari Kromatografi Lapis Tipis Secara Kemometrik Daun Tumbuhan Anting-Anting (Acalypa Indica L.) Berdasarkan Lokasi Tumbuh Hidayaty, Alfianita Nuril; Hayati, Elok Kamilah
ALCHEMY:Journal of Chemistry Vol 12, No 1 (2024): ALCHEMY: JOURNAL OF CHEMISTRY
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/al.v12i1.22130

Abstract

Anting-anting plant (Acalypha indica L.) is a tropical plant with abundant secondary metabolite content, so its content can be used as traditional medicine. One of the secondary metabolites is influenced by the location of growth in different groups of compounds and levels. Information related to secondary metabolites can be used for quality control. This study aims to determine the effect of differences in growing locations on levels and secondary metabolites in the Tuban, Bojonegoro, and Ngawi regions. The method used is Thin Layer Chromatography (TLC) followed by the Orange 3.32 Principal Component Analysis (PCA) chemometric method to obtain the grouping and concentration of each sample. The results of the TLC separation obtained 10 sample spots from the Tuban area, 10 sample spots from the Bojonegoro area, and 13 sample spots from the Ngawi area. PCA multivariate analysis explained that the total data variation was 91% (PC 1= 52.5%; PC 2= 38.5%). These results indicate that there are differences in the levels and groups of active compounds with different Area Under Curve (AUC) values for each sample of the earring leaf extract.

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