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Jurnal Kesehatan
Published by Universitas Islam Negeri Alauddin Makassar
ISSN : 20862555     EISSN : 26227363     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology Nursing Public Health
Jurnal Kesehatan is an academic journal that publishes medical and health scientific articles. We regularly publish the issues in June and December. The journal accepts research-based papers, literature/health research regarding of pharmacy, nursing public science and midwifery. This journal published by Medical and Health Science Faculty, Universitas Islam Negeri Alauddin Makassar.
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Articles 206 Documents
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PERAN GURU DAN KEJADIAN OBESITAS PADA SISWA SEKOLAH DASAR DI KOTA MEDAN Desty Adinda; Etti Sudaryati; Putra Apriadi Siregar
Jurnal Kesehatan Vol 13 No 1 (2020): JURNAL KESEHATAN
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v13i1.10898

Abstract

Saat ini banyak sekali ditemukan anak-anak yang mengalami obesitas Obesitas termasuk pada siswa sekolah dasar. Obesitas menjadi permasalahan yang sangat serius bagi siswa sekolah dasar karena akan dapat memicu terjadinya berbagai penyakit degeneratif kedepannya. Salah satu yang memiliki peran penting dalam pencegahan obesitas pada siswa sekolah dasar adalah guru, hal ini disebabkan guru memiliki waktu yang lama bersama siswa sekolah dasar di sekolah.Penelitian ini bertujuan untuk menganalisis peran guru dan kejadian obesitas siswa sekolah dasar di kota Medan. Jenis penelitian ini adalah kuantitatif dengan desain penelitian cross sectional. Populasi dari penelitian ini adalah anak sekolah dasar di Kota Medan dan sampel dalam penelitian ini adalah siswa sekolah dasar sebanyak 309 siswa kelas lima sekolah dasar di Kota Medan. Pengumpulan data dilakukan dengan menggunakan kuesioner kepada siswa sekolah dasar untuk menilai peran guru dan pengukuran antopometri IMT/U untuk tingkat obesitas. Analisis data yaitu univariat, bivariat dengan uji chi square.Hasil penelitian ini menunjukkan bahwa peran guru tidak berhubungan dengan kejadian obesitas anak sekolah (p=0,713). Terdapat hubungan antara perang orangtua dengan kejadian obesitas (p=0,016). Diharapkan kepada guru untuk memperhatikan siswa sekolah dasar yang obesitas dengan mengawasi kebiasaan makan anak yang berlebihan dan meningkatkan aktivitas fisik anak. Guru diharapkan dapat berkoordinasi dengan orangtua siswa sekolah dasar untuk menerapkan sarapan sehat dirumah agar mengurangi konsumsi jajan di sekolah.
HUBUNGAN KARAKTERISTIK INDIVIDU TERHADAP PERILAKU MENGENAI COVID-19 DI DESA GULINGAN, MENGWI, BALI Made Sindy Astri Pratiwi; Made Violin Weda Yani; Agus Indra Yudhistira Diva Putra; I Wayan Gita Mardiana; I Komang Ari Adnyana; Nyoman Manik Mas Genitri Putri; Ni Putu Sri Widi Adnyani Karang; I Putu Yudhi Setiawan
Jurnal Kesehatan Vol 13 No 2 (2020): JURNAL KESEHATAN
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v1i1.16340

Abstract

Covid-19 is a contagious infectious disease that continues to increase as a global pandemic. Everyone from all individual characteristic must have good behaviors to prevent Covid-19 as a pandemic. Until now, there has been no research that analyzes the relationship between individuals characteristic and the behavior of the Covid-19 pandemic in Bali. This research is a cross sectional observation located in Gulingan Village. The research subjects were 120 people aged 13-56 years who were selected by simple random sampling. The level of obedience behavior towards Covid-19 was assessed using a questionnaire. The collected data will be analyzed in univariate and bivariate ways. The subjects of this study were dominated by respondents aged ≥19 years (60%), female gender (52.5%), college (50%), student / college student (72.5%), low risk of infection status (95.8%), good obedience behavior level (52.5%). There is a significant relationship between gender and the level of behavior regarding Covid-19, but there is no significant relationship between age, education, occupation, and risk status on obedience behavior to Covid-19. Almost every individual has a relationship with behavior in facing Covid-19 due to various factors. Commitment to awareness, perception, and knowledge about health in each individual can influence good behavior in preventing Covid-19. Obedient behavior implementing health protocols is the key to prevent the transmission of Covid-19 transmission. This study shows a significant relationship between gender and behavior regarding the Covid-19 pandemic but not with age, education, occupation, and risk status.ABSTRAKCovid-19 adalah penyakit infeksi menular yang terus meningkat sebagai pandemi global. Setiap karakteristik individu dari berbagai lapisan masyarakat harus memiliki perilaku yang benar mengenai intervensi Covid-19 sebagai upaya preventif melawan pandemi ini. Hingga saat ini belum ada penelitian yang menganalisis hubungan antara karakteristik individu terhadap perilaku masyarakat terhadap pandemi Covid-19 di Bali. Penelitian ini merupakan observasi cross sectional yang berlokasi di Desa Gulingan. Subjek penelitian berjumlah 120 orang berusia 13-56 tahun yang dipilih dengan simple random sampling. Tingkat perilaku ketaatan terhadap Covid-19 dinilai menggunakan kuesioner. Data yang terkumpul akan dianalisis secara univariat dan bivariat. Subjek penelitian ini didominasi oleh responden berusia ≥19 tahun terdapat 60%, jenis kelamin perempuan 52,5%, perguruan tinggi 50%, bekerja sebagai siswa/mahasiswa 72,5%, status risiko infeksi rendah 95,8%, tingkat perilaku ketaatan baik 52,5%. Terdapat hubungan yang signifikan antara jenis kelamin dengan tingkat perilaku mengenai Covid-19, namun tidak didapatkan hubungan yang signifikan antara usia, pendidikan, pekerjaan, dan status risiko terhadap perilaku ketaatan terhadap Covid-19.Hampir setiap karakteristik individu memiliki keterkaitan dengan perilaku menghadapi Covid-19 karena adanya berbagai faktor. Komitmen kesadaran, persepsi, hingga pengetahuan mengenai kesehatan pada tiap individu dapat memengaruhi perilaku yang baik dalam mencegah Covid-19. Perilaku yang taat menerapkan protokol kesehatan merupakan kunci untuk mencegah transmisi penularan Covid-19. Penelitian ini menunjukkan adanya hubungan yang signifikan antara jenis kelamin dengan perilaku mengenai pandemi Covid-19 namun tidak dengan usia, pendidikan, pekerjaan, dan status risiko.
PERBANDINGAN AKTIVITAS PENGHAMBATAN ENZIM TIROSINASE OLEH FRAKSI ETIL ASETAT DAUN PATIKALA (Etlingera elatior) DAN HIDROKUINON SECARA In Vitro Selfyana Austin Tee; Apriyanto Apriyanto; Musdalipah Musdalipah; Elfirah Elfirah
Jurnal Kesehatan Vol 13 No 1 (2020): JURNAL KESEHATAN
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v13i1.10309

Abstract

Etlingera is one of the genus Zingiberacea which consists of 150 - 200 species in the world, and there are 48 species that grow in Sulawesi and 14 species of which are scattered in Sulawesi. Patikala (Etlingera elatior) has a bioactive compound in the form of flavonoids. Withdrawal of flavonoid compounds in plants is carried out using ethyl acetate solvents. One of the enzymes in the body is the tyrosinase enzyme. The tyrosinase enzyme is the main pathway in the pigmentation process, causing melanin pigment. This study aims to compare the inhibitory activity of the tyrosinase enzyme in the paticala fraction of ethyl acetate (Etlingera elatior) and hydroquinone in vitro. The research method used was a quasi experimental consisting of the treatment group and the control group with measurements made after the treatment was given (posttest only design with non equivalent group). Concentration of ethyl acetate fraction of patikala leaves used were 7.8125 µg / mL, 15,625 µg / mL, 31.25 µg / mL, 62.5 and 125 µg / mL with positive control of hydroquinone, respectively. Based on the results obtained, Inhibitory activity of the tyrosinase enzyme by the paticala leaf ethyl acetate fraction with a concentration of 125 μg. The inhibitory activity of the tyrosinase enzyme by both samples increased with increasing concentration
HUBUNGAN TINGKAT RELIGIUSITAS TERHADAP INTENSITAS KENAKALAN REMAJA ANAK SEKOLAH DI SMK YBKP3 GARUT Iwan Shalahuddin; Ahmad Yamin; Umar Sumarna
Jurnal Kesehatan Vol 14 No 1 (2021): JURNAL KESEHATAN
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v14i1.16504

Abstract

Juvenile delinquency among high school students is the result of those who have issues in mental or psychological development. The aim of this study is to relationship between religiosity and intensity of juvenile delinquency among high school students. This study used quantitative approach and the design applied was product-moment correlation. For bivariate analysis purposes, one-way ANOVA was used to test compare mean. The total population of this study was 387 teenage students who have both good and bad behavior in terms of religiosity. The instrument used had been valid with the value of point biseral correlation from 0.126 to 0.617 with the alpha of 0.05. The reliability value obtained was alpha 0.80. The results showed that there was no difference between the religious level and the anger level based on the student's age (P-value) = 0.967, student class (0.976) and gender (0.991). The conclusion obtained is that the religious level of students obtained is high or good as many as 192 students (49.6%). This shows that the subject believes and believes in things that are fundamental and dogma in religion. Recommendations are given to always maintain well-applied arrangements, and need to be developed to correct all deficiencies and mistakes in an effort to prevent delinquency among school children. 
MOUTHWASH JUS BUAH NANAS (Ananas comosus L. Merr) TERHADAP BAKTERI Streptococcus mutans Sri Wahyuningsih; Nielma Auliah; Salwi Salwi
Jurnal Kesehatan Vol 13 No 2 (2020): JURNAL KESEHATAN
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v13i2.16423

Abstract

This research aimed to determine the formulation of pineapple juice into mouthwash and to investigate antibacterial activity against Streptococcus mutans. This was an experimental design method, it started by formulating pineapple juice (Ananas comosus L.Merr) into mouthwash and testing the activity of bacteria using the agar diffusion method to determine the inhibition zone. The research result showed that pineapple juice (Ananas comosus L.Merr) can be formulated into mouthwash with a concentration of 5%; 10%; and 15% and there was no significant difference after the stability test. The mouthwash also has antibacterial activity against Streptococcus mutans with a zone of inhibition for a concentration of 5%; 10% and 15%, respectively 8.6 mm; 9.4 mm; and 9.7 mm. Antibacterial activity of pineapple juice mouthwash against Streptococcus mutans showed a moderate inhibition zone category.ABSTRAKPenelitian ini bertujuan untuk mengetahui jus buah nanas dapat diformulasi dalam bentuk sediaan mouthwash dan aktivitas antibakteri mouthwash terhadap bakteri Streptococcus mutans. Penelitian ini termasuk penelitian eksperimental laboratorium dengan memformulasi sediaan dan menguji aktivitas bakteri menggunakan metode difusi agar untuk mengetahui zona hambat sediaan mouthwash jus buah nanas (Ananas comosus L.Merr). Hasil penelitian menunjukkan bahwa jus buah nanas (Ananas comosus L.Merr) dapat diformulasi menjadi sediaan mouthwash dengan konsentrasi 5%; 10%; dan 15% dan tidak terjadi perbedaan signifikan setelah uji kestabilan. Mouthwash juga memiliki aktivitas antibakteri terhadap Streptococcus mutans dengan rata-rata zona hambat untuk konsentrasi 5%; 10% dan 15% masing-masing 8,6 mm; 9,4 mm dan 9,7 mm. Aktivitas antibakteri mouthwash jus buah nanas terhadap bakteri Streptococcus mutans menunjukkan kategori zona hambat sedang.
POTENSI LACTOBACILLUS PLANTARUM SEBAGAI INTERVENSI PENATALAKSANAAN KANKER KOLOREKTAL BERBASIS MODIFIKASI MIKROBIOTA USUS Anak Agung Bagus Putra Indrakusuma; I Gede Krisna Arim Sadeva; Putri Ayu Wulandari; I Gede Wikania Wira Wiguna; Ni Putu Sri Indrani Remitha; I Gusti Ayu Stiti Sadvika; I Gede Putu Supadmanaba; Desak Made Wihandani
Jurnal Kesehatan Vol 13 No 2 (2020): JURNAL KESEHATAN
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v13i2.17044

Abstract

Colorectal cancer is a cancer of the colon including the colon and rectum with symptoms such as blood in the stool, anemia, and abdominal pain. This is the third most common cancer worldwide and causes 30.017 cases in Indonesia on 2019. Current treatment of colorectal cancer includes the administration of chemotherapy, surgery, and radiotherapy. However, they are considerably expensive and have many side effects. Lactobacillus plantarum (L. plantarum) is known to have an anticancer effect by influencing carcinogenesis in cell proliferation, apoptosis, and stimulates anticancer immunity. This literature review aims to examine the potential of L. plantarum as an intervention in the management of colorectal cancer based on the modification of the gut microbiota. The writing method used is literature study by examining library sources from five research engines, namely Google Scholar, Pubmed, Plos ONE, Nature, and Sciencedirect. After going through the screening, 79 relevant sources were obtained which were then processed and compiled systematically. L. plantarum suppresses proliferation by inhibiting G1 phase in the cell cycle and targetting ErbB2 and ErbB3. In addition, L. plantarum induces cell death (apoptosis) by activating Bcl-2. These bacteria also stimulate Th1 and inhibit Th2 immune responses.ABSTRAKKanker kolorektal merupakan kanker pada usus besar meliputi kolon dan rektum dengan beberapa gejala seperti darah dalam tinja, anemia, dan nyeri perut. Kanker ini menempati peringkat ketiga di dunia dan menyebabkan 30.017 kasus di Indonesia pada tahun 2019. Penanganan kanker kolorektal saat ini meliputi pemberian obat anti-kanker, pembedahan, dan radioterapi. Akan tetapi, penanganan saat ini dinilai mahal dan menimbulkan efek samping. Salah satu mikrobiota usus, yaitu Lactobacillus plantarum (L. plantarum) diketahui memiliki efek antikanker dengan memengaruhi karsinogenesis pada proliferasi sel, apoptosis, dan sebagai imunoterapi. Metode penulisan yang digunakan adalah studi literatur dengan mengkaji sumber kepustakaan dari lima research engine yaitu Google Scholar, Pubmed, Plos ONE, Nature, dan Sciencedirect. Setelah melalui skrining diperoleh 79 sumber relevan yang kemudian diolah dan disusun secara sistematis. L. plantarum menekan proliferasi melalui mekanisme penghentian fase G1 pada siklus sel dengan target reseptor ialah ErbB2 dan ErbB3. Selain itu, L. plantarum mampu menginduksi kematian sel (apoptosis) dengan mediasi Bcl-2. Bakteri ini juga berperan dalam imunoterapi dengan menstimulasi Th1 dan menghambat Th2 pada host immune system. Literature review ini bertujuan untuk mengkaji potensi L. plantarum sebagai intervensi penatalaksanaan kanker kolorektal berbasis modifikasi mikrobiota usus. 
AKTIVITAS PENGHAMBATAN FRAKSI DAUN DELIMA (Punica granatum L.) TERHADAP BAKTERI Mycobacterium tuberculosis Afrisusnawati Rauf; Nurshalati Tahar; Resnia Resnia
Jurnal Kesehatan The 1st Alauddin Pharmaceutical Conference and Expo (ALPHA-C) 2019
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v0i0.18044

Abstract

Punica granatum L., commonly known as pomegranate, has emerged as a medicinal plant with potential antimicrobial activity. This study aims to identify this activity against the bacteria Mycobacterium tuberculosis. Pomegranate leaf extract is made using solvents (ethanol 96%), then partitioned using n-butanol solvents and fractionated using vacuum liquid chromatography method. After obtaining the fractional results, the inhibitory activity effect of the fraction was studied using the Mycobacterium tuberculosis H37RV strain and compared to commercial antibiotic Isoniazid using the MODS method. Pomegranate leaf fraction shows antibacterial activity against Mycobacterium tuberculosis at a concentration of 1000 ppm, as seen from the absence of cord at such concentrations. Therefore this plant can be an important source of new antimicrobial compounds to treat the bacteria Mycobacterium tuberculosis.
RESPIRATORY MUSCLES TRAINING (RMT) TO DYSPNEA SCALE OF COPD: A SYSTEMATIC REVIEW Imron Rosyadi; Shinta Dewi Kasih Bratha
Jurnal Kesehatan Vol 14 No 1 (2021): JURNAL KESEHATAN
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v14i1.16468

Abstract

SummaryBackground: COPD can decrease patients' activity because of dyspneaObjectives: To critically evaluate the effect of RMT as a treatment of COPD.Method: Five databases were found from 2008, a randomized clinical trials (RCTs) research will be a reference if they evaluated RMT against any type of control in patients with any form of respiratory muscle weakness.Result: Five trials met the inclusion criteria. One journal has the good of sampling technic by using the COPD patient from 3 hospitals. Only four journals show the significant effect of RMT to decrease dyspnea of COPD. The impact of RMT is going to increase the lung capacity, lung function, activity, respiratory muscle straightness, and minimize the effort of breathing. Only one journal does this intervention for 12 weeks.Conclusion: The evidence for the effect of RMT to decrease the dyspnea scale has a significant impact. For future studies, it will be better to use RMT longer to get a more considerable impact.  
EFEK ANTI-MIKROBIAL PADA EKSTRAK CINNAMOMUM VERUM (KAYU MANIS) SEBAGAI TERAPI ADJUVANT PADA MALARIA FALCIPARUM Isma Fadlilatus Sa'diyah
Jurnal Kesehatan Vol 14 No 1 (2021): JURNAL KESEHATAN
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v14i1.15819

Abstract

Malaria is a major public health problem in the world, especially in Indonesia. The prevalence of malaria in Indonesia reaches 6 percent, which is mostly caused by plasmodium falciparum. Various treatment options for malaria falciparum have been developed, but due to various factors, such as the adherence to taking medication from patients are not monitored so that it can increase the risk of resistance to current malaria therapy. Therefore, the researchers conducted further research on alternative malaria therapies. Cinnamomum verum or cinnamon is known to contain cinnamaldehyde compounds which have an antimicrobial effect. The purpose of this study was to determine the anti-microbial effect of Cinnamomum verum extract or cinnamon extract as adjuvant therapy in malaria falciparum. This type of study is a literature review with the method of collecting reading results from 25 articles of case reports, research articles, and literature reviews. This study concludes that the cinnamaldehyde compound in Cinnamomum verum extraction has an antimicrobial effect which can inhibit the denaturation potential of amino acids, inhibits β-hematin formation and activity of the reductase enzyme on Plasmodium falciparum enoyl-ACP reductase, where it is known that these four have an important role. in the pathogenesis of falciparum malaria.
STUDI AKTIVITAS INHIBITOR TIROSINASE DAN KADAR FENOLIK TOTAL EKSTRAK METANOL JAMUR TIRAM PUTIH (Pleurotus ostreatus) Nur Syamsi Dhuha; Nur Suci Suci Wahdaniya; Syamsuri Syakri
Jurnal Kesehatan THE 2nd ALAUDDIN PHARMACEUTICAL CONFERENCE AND EXPO (ALPHA-C) 2020
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/kesehatan.v1i1.18166

Abstract

Oyster mushroom (Pleurotus ostreatus) contains vitamin B, vitamin C and carbohydrates such as β-glucans, monoterpenoids, triterpenoids, potential sources of lignin and phenols. The presence of phenolic compounds indicates the ability of oyster mushrooms as potential antioxidants and anti-tyrosinases. Searching for depigmentation agents in cosmetics is necessary to ensure safety and reduce side effects. The aims of this study are to determine the inhibitory activity of tyrosinase and total phenolic levels of Pleurotus ostreatus methanol extract. Tyrosinase inhibitor activity was measured using the Enzyme Linked Immunosorbent Assay (ELISA) method at 490 nm with various concentrations, which were 55 ppm, 65 ppm, 75 ppm, 85 ppm and 95 ppm. Determination of total phenolic levels at a concentration of 100 ppm using a UV-Vis Spectrophotometer at 744.8 nm. Based on the research, the percentage of tyrosinase inhibitor of Pleurotus ostreatus methanol extracts at concentrations of 55 ppm, 65 ppm, 75 ppm, 85 ppm and 95 ppm were 17.6%, 19.5%, 22.2%, 25.9%, and 35.7%, respectively. The result of the IC50 and total phenolic content are 9.06% and 1.13%. These results exhibit that the methanol extract of Pleurotus ostreatus has a very strong tyrosinase inhibitor power.

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