cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Current Biochemictry
Contact Email
current.biochemistry@gmail.com
Phone
-
Journal Mail Official
imart171@yahoo.com
Editorial Address
-
Location
Kota bogor,
Jawa barat
INDONESIA
Current Biochemistry
Published by Institut Pertanian Bogor
ISSN : 23557877     EISSN : 23557931     DOI : -
Core Subject : Science, Education,
Biochemistry, Genetics & Molecular Biology Education
Current Biochemistry (CB) publishes the results of original research that contribute significantly to the understanding of the chemical compound and reaction that occur within living organism. Preference will be accorded to manuscripts that develop new concepts or experimantal approaches, particularly in the advancing areas of biochemistry science. Manuscripts that are primarily theoretical in nature or in the field of bioinformatics must be directed toward explaining important results previously not understood, making important predictions that can be experimentally tested, or developing segnificant advances in theory of general interest to biochemists. Submission of manuscripts in emerging areas in biochemistry, chemical biology, biophysics, proteomics, model studies and structures, cellular and molecular biology, computational biochemistry, biotechnology, and new methods development is encouraged especially if they address basic biochemical mechanisms.
Arjuna Subject : -
Articles 111 Documents
 3   4   5   6   7 
Application of Liquid Organic Fertilizer (Bio-fertilizer) Enriched Consortium Bacteria and Golden Snail (Pamoacea canliculata) in Ciherang Rice Flowering Agus Setiawan; Maria Bintang; Syamsul Falah
Current Biochemistry Vol. 3 No. 2 (2016)
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Application of organic fertilizer today has become a necessity, benefits can be felt by farmers using organic fertilizers because increasing content of organic matter and soil nutrition so that increased productivity of agricultural land. Golden snail (Pomacea canaliculata) was introduced to Asia in the 1980s from South America as a potential food for humans. nutritional content of golden snails when added to other ingredients can be a good growth medium for growth of various types of bacteria (consortium) as basic ingredients of liquid organic fertilizer (Bio-fertilizer). Bio-fertilizer was made from golden snail plus consortium bacteria which then carried out isolation and calculation number of bacterial colonies that grow, test activity of phosphate solvent, nitrogen fixation and effectiveness of Ciherang rice flowering. Bio-fertilizer applications made in combination with solid organic fertilizers significantly increase plant height, number of tillers, multiply and accelerate flowering of Ciherang rice.
Antimicrobial activity and identification of bioactive compounds of Söfö-söfö (Acmella cf) leaf extract using GC-MS Maria bintang; Faoziduhu Bawamenewi; Mega Safithri; Fachriyan H Pasaribu
Current Biochemistry Vol. 3 No. 2 (2016)
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Söfö-söfö is a traditional medicinal plant from Nias Island that can cure fever, cough, diarrhea and fungal infections on the skin. However, the scientific basis of these plants is unknown. The aim of this research was to extract the Söfö-söfö leaf by maceration method using two solvents that were 70 % ethanol and ethyl acetate, to test the antimicrobial activity of the extract by Agar diffusion method against Staphylococcus aureus, Eschercia coli, and Candida albican, and analyze secondary metabolite compounds by fitochemistry test and to determine the components of bioactive compounds by GC-MS. The results showed that the best solvent for making Söfö-söfö extract as antimicrobial is ethyl acetate with a minimum inhibitory concentration of 4000 ppm to S. aureus (1.25 ± 0.35 mm), E. coli (1 mm) and C. albican 6000 ppm (1.5 mm). The secondary metabolite compounds of ethyl acetate extract were alkaloids, flavonoids and steroids. Bioactive compounds found in the Söfö-söfö ethyl acetate extract with potential antimicrobial activity were hexadecanoic acid, stigmasterol, neophytadiene, methyl ester, squalene and phytol.
Effect of Boiled Cassava Leaves (Manihot esculenta Crantz) on Total Phenolic, Flavonoid and its Antioxidant Activity Hasim Hasim; Syamsul Falah; Lia Kusuma Dewi
Current Biochemistry Vol. 3 No. 3 (2016)
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Cassava leaves (Manihot esculenta Crantz) widely used as vegetables in many regions. Cassava leaves contain many minerals such as Fe, Zn, Mn, Cu, Mg, Ca, P, K, S, contain crude protein, β-carotene and have an active compound of flavonoids, phenolic, and contain chlorophyll which is a natural antioxidant. The aims of this study were to analyze the effect of boiled cassava leaves on total phenolics, flavonoids, and its antioxidant activity. Cassava leaves extraction was done by maceration method to obtain the methanol extract and infundation method to get the water extract. Based on phytochemical test, cassava leaves contained alkaloids, flavonoids, phenolic, tannins, and saponins. The highest levels of total phenolics and flavonoids contained in the methanol extract of simplicia, 30.57 mg GAE/g and 881.33 mg RE/g, respectively. Cassava leaves extract had potential as an antioxidant with the highest inhibition of DPPH radicals produced by the methanol extract of simplicia with IC50 values of 92.10 mg/L and followed by methanol extract of boiled leaves, water extract of simplicia, and water extract of boiled leaves with IC50 144.28, 155.76 dan 170.71 mg/L , respectively. In conclusion, the process of boiling cassava leaves could reduce total phenolic, total flavonoids and antioxidant activcity.
Antibacterial Activity of Ethanol Extract from Stem Bark and Leaves of ­Berenuk (Crescentia cujete L.) Uswatun Hasanah; Desi Rosdiana; Syaefudin Syaefudin
Current Biochemistry Vol. 4 No. 1 (2017)
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Crescentia cujete L. (C. cujete) has been known as a medicine for various diseases that caused by microorganisms. This research was aimed to identify the phytochemical compounds and to determine the antibacterial activity of ethanolic extracts from stem bark and leaves of C. cujete. The phytochemical compounds in both extracts were identified by Harborne method, while antibacterial activity assay was performed by disc diffusion method with the concentration of bacteria 106 cfu/mL. Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) were used in antibacterial assay. Minimum Inhibitory Concentration (MIC) was obtained by using contact method. The phytochemical compounds analysis showed that ethanol extracts of C. cujete stem bark and leaves contained alkaloids, flavonoids, saponins, tannins, and steroids. The results of antibacterial activity test showed that both extracts have antibacterial activity with the highest inhibition showed by extracts with concentration of 100 %(w/v). The decreased percentage in the number of bacterial colonies on the extracts was less than 90 % so that the MIC value of both extracts against S. aureus could not be determined.
Aktivitas Antioksidan Ekstrak Etanol dari akar, batang, dan daun Sereh Wangi (Cymbopogon nardus L) Waras Nurcholis; Hartanti Hartanti; Hyakansa Hyakansa; Maria Magdalena; Tubagus Iqbal Maulana
Current Biochemistry Vol. 4 No. 2 (2017)
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

-
Uji Fitokimia dan Identifikasi Senyawa-Senyawa Metabolit Sekunder Ekstrak Etil Asetat, Etanol dan Air Tanaman Zingiber zerumbet Asal Pulau Timor Origenes Boy Kapitan; Laksmi Ambarsari; Syamsul Falah
Current Biochemistry Vol. 3 No. 3 (2016)
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

-
Antibacterial Activity and Phytochemical Analysis of Geranium homeanum Turez Leaves Fri Rahmawati; Maria Bintang; I Made Artika
Current Biochemistry Vol. 4 No. 3 (2017)
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Geranium homeanum Turez is a herbaceous plant used as an empirical medicine. This research was carried out to test the antibacterial activity and determine minimum inhibition concentration (MIC) to Staphylococcus aureus and Pseudomonas aeruginosa with agar diffution method and phytochemical analysis of geranium leaves  by Harbone method. The young and old geranium leaves were blended then filtrated. The obtained filtrate was divided into two parts, one part heated by autoclave and the other was unheated. Each filtrate was tested against to Staphylococcus aureus and Pseudomonas aeruginosa. Geranium leaves filtrate having the highest antibacterial activity was heated at 500C until it  become dry powder.  The powder was used to measure MIC and phytochemical analysis.The results showed that the antibacterial activity of young leaves filtrate was higher than the old leaves filtrat, and the unheated leaves filtrate was higher than heated filtrate one. MIC of S. aureus and P. aeruginosa, were as follows 15 mg/ml and 20 mg/mL respectively. The antibacterial activity of powder geranium’s leaves  filtrate was weaker than 100 µg/mL ampicilline. Phytochemical analysis of geranium leaves showed positive contents of alkaloid and triterpenoid.
Toxicity Extract and Faction of Surian Toona sinensis Leaf and Bark against Shrimp Larvae Artemia salina L. Rori Theresia; Syamsul Falah; Mega Safithri; Muhammad Assyar
Current Biochemistry Vol. 3 No. 3 (2016)
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Surian (Toona sinensis) is one of the herbs that contain many bioactive compounds. Part of surian plants that can be utilized as therapy is leaf and bark. This study aims to determine the toxicity of leaf and bark extract of Surian through Bhrine Shrimp Lethality Test (BSLT), then compare toxic concentration of water extract, and ethanol 70 %, and n-hexane, diethyl ether and ethyl acetate fractions to shrimp larvae (Artemia salina L). The results showed that water content of leaves simplicia was 8.08 % and bark was 6.26 %. The highest extract rendement value by ethanol solvent was 23 %. The result of BSLT test probit analysis showed that the extract of ethyl acetate bark fraction had the highest toxicity with LC50 value 405.641 ppm, while leaf water extract had the lowest toxicity with LC50 value 707.787 ppm.
The Usage of Momordica charantia as Face Cleansing Cosmetics: Momordica charantia Leaves Extract as Absorbent of Heavy Metal, Surface Tension Reducer and Skin Antibacterial Dimas Andrianto; Popi Asri Kurniatin; Silvy Aulya; Dewi Eriyanti
Current Biochemistry Vol. 3 No. 3 (2016)
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Momordica charantia (daun pare in Indonesian) is one of Indonesian herbal plants which useful property has not been explored. M. charantia contains chemical substances such as oil and saponin. Nowadays, the society possesses a high awareness regarding the risk of using artificial chemicals for skin care and more people are switching to use herbal cosmetics. The extract of M. charantiahas been proven to be able to be used as one of the active components of herbal based facial cleansing cosmetics. Its active properties include its ability to absorb heavy metal from air pollution and motor vehicles emission, decrease surface tension, and to act as an antibacterial agent.In the research, M.charantia was extracted using 4 (four) solvents, namely water, ethanol, methanol, and hexane. The research then examined the property of each extract in metal absorption (using Atomic Absorption Spectrophotometry / AAS), decreasing surface tension, and antibacterial activities. The result of the test showed that the water based extract was the most effective extract in reducing surface tension and in inhibiting the development of Escherichia coli and Staphylococcus aureus bacteria, while the ethanol based extract was the most effective one in absorption of Pb and Hg metals and in inhibiting the development of Staphylococcus epidermidis bacteria. The result indicated that M. charantiaextract has the potentials to be used as facial cleanser and can also counter the bacterial infection which could cause acnes.
Antibacterial Activities of Sirih Merah (Piper crocatum) Leaf Extracts Puspa Julistia Puspita; Mega Safithri; Nirmala Peni Sugiharti
Current Biochemistry Vol. 5 No. 3 (2018)
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Piper crocatum is one of medicinal herbal plants with a large number of benefits. Usually herbal plants have activity as antibacterial agent. Therefore, the objectives of this research were to obtain information on antibacterial activities of the leaf extracts of Piper crocatum againts four types of bacteria, in that Staphylococcus, Bacillus substilis, Escherichia coli, and Pseudomonas aeruginosa and then to analyze the phytochemistry of the leaf extracts of Piper crocatum. The leaves of Piper crocatum were extracted by maceration and reflux using ethanol 30%. The assays of the antibacterial activities and phytochemistry on the extracts were carried out using the method of Maria Bintang. Results showed that the yield of the extraction using ethanol by maceration method was 20.8%. Meanwhile, using the reflux method, the yield was obtained about 26.25%. The phytochemistry analysis showed that the leaf extracts of Piper crocatum contained alkaloid, steroid and tanin. According to this study, it was found that the leaf extract of Piper crocatum can be used to inhibit the growth of B. subtilis and P. aeuruginosa, but can not inhibit the growth of E.coli and S. aureus.

Page 5 of 12 | Total Record : 111

 3   4   5   6   7 

Filter by Year

2014 2025


Reset
Filter By Issues
All Issue Vol. 12 No. 1 (2025): Vol. 12 No. 1 (2025) Vol. 12 No. 1 (2025): 2025 Vol. 11 No. 1 (2024) Vol. 10 No. 2 (2023) Vol. 10 No. 1 (2023) Vol. 9 No. 2 (2022) Vol. 9 No. 1 (2022) Vol. 8 No. 2 (2021) Vol. 8 No. 1 (2021) Vol. 7 No. 2 (2020) Vol. 7 No. 1 (2020) Vol. 6 No. 2 (2019) Vol. 6 No. 1 (2019) Vol. 5 No. 3 (2018) Vol. 5 No. 2 (2018) Vol. 4 No. 3 (2017) Vol. 4 No. 2 (2017) Vol. 4 No. 1 (2017) Vol. 3 No. 3 (2016) Vol. 3 No. 2 (2016) Vol. 3 No. 1 (2016) Vol. 2 No. 3 (2015) Vol. 2 No. 2 (2015) Vol. 2 No. 1 (2015) Vol. 1 No. 3 (2014) Vol. 1 No. 2 (2014) Vol. 1 No. 1 (2014) More Issue